Tag: M.W=350-400

Ding, Yun published the artcileDesign and Synthesis of Biaryl DNA-Encoded Libraries, HPLC of Formula: 363186-06-5, the publication is ACS Combinatorial Science (2016), 18(10), 625-629, database is CAplus and MEDLINE.

DNA-encoded library technol. (ELT) is a powerful tool for the discovery of new small-mol. ligands to various protein targets. Here we report the design and synthesis of biaryl DNA-encoded libraries based on the scaffold of 5-formyl 3-iodobenzoic acid. Three reactions on DNA template, acylation, Suzuki-Miyaura coupling and reductive amination, were applied in the library synthesis. The three cycle library of 3.5 million diversity has delivered potent hits for phosphoinositide 3-kinase α (PI3Kα).

ACS Combinatorial Science published new progress about 363186-06-5. 363186-06-5 belongs to esters-buliding-blocks, auxiliary class Boronic acid and ester,Amine,Benzene,Amide,Boronate Esters,Boronic Acids,Boronic acid and ester,Boronate Esters, name is Benzyl (4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate, and the molecular formula is C20H24BNO4, HPLC of Formula: 363186-06-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Li, Ming published the artcilePhotochromic holo-cellulose wood-based aerogel grafted azobenzene derivative by SI-ATRP, Synthetic Route of 135529-02-1, the publication is Carbohydrate Polymers (2021), 117736, database is CAplus and MEDLINE.

Wood is actually a natural polymers composite that is easy to process, mainly constituted of cellulose, hemicellulose and lignin. However, most wood-based functional materials are prepared by phys. methods, which undoubtedly limit the application of wood-based materials. Herein, the wood aerogel (WA) was obtained from wood by delignification and freezing dried. The WA then was fabricated into an unexpected photochromic wood aerogel (PWA) via surface-initiated atom transfer radical polymerization (SI-ATRP) covalently grafting poly{6-[4-(4-methoxyphenyl-azo)phenoxy]hexyl methacrylate} (PMAZOM). Both WA and PWA showed good compression resilience. The hydrophobicity of PWA was obviously enhanced because of the surface modification. The color of PWA can change from yellow to orange-red after being irradiated by UV light for 30 s. The color of sample can be reversibly changed to yellow under sunlight for 200 s. The lightweight and photosensitive wood aerogel is potential to apply for optical information storage materials and photosensitive devices.

Carbohydrate Polymers published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C23H28N2O4, Synthetic Route of 135529-02-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hale, Dylan J. published the artcile(PSiP)Ni-Catalyzed (E)-Selective Semihydrogenation of Alkynes with Molecular Hydrogen, Application In Synthesis of 1448637-05-5, the publication is ACS Catalysis (2022), 12(1), 146-155, database is CAplus.

It was reported that the bis(phosphino)silyl Ni hydride complex (ⁱPr-PSiP^Ind)NiH, I is an effective pre-catalyst for the (E)-selective semihydrogenation of a broad range of diaryl alkynes and SiMe₃-protected terminal alkynes. Complex I exhibited this reactivity under mild conditions (1 atm H₂, 25-50°C, and 1-2.5 mol % Ni) to afford the corresponding (E)-alkenes with high selectivity. Stoichiometric experiments revealed that facile alkyne insertion and subsequent alkene isomerization led to the observed selectivity.

ACS Catalysis published new progress about 1448637-05-5. 1448637-05-5 belongs to esters-buliding-blocks, auxiliary class Alkynyl,Boronic acid and ester,Benzene,Ester,Boronate Esters,Boronic Acids,Boronic acid and ester,, name is Methyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)benzoate, and the molecular formula is C22H23BO4, Application In Synthesis of 1448637-05-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Yingying published the artcileSelf-assembly and photo-responsive behavior of novel ABC₂-type block copolymers containing azobenzene moieties, Category: esters-buliding-blocks, the publication is Soft Matter (2012), 8(11), 3131-3138, database is CAplus.

The self-assembly behavior and photo-responsive properties of novel azobenzene based copolymers poly(ethylene oxide) monomethyl ether-block-polystyrene-block-{poly[6-(4-methoxy-azobenzene-4′-oxy)hexyl methacrylate]}₂ [MPEO-b-PS-b-(PMMAZO)₂] with various block lengths of PMMAZO segments in aqueous media were studied by means of transmission electron microscopy (TEM), SEM, laser light scattering (LLS) and UV-Vis spectrophotometry. It was found that the critical water content for the aggregate formation increases with the PMMAZO weight fraction. By tailoring the mol. structure and copolymer concentration, various self-assembled aggregates were obtained. At a lower concentration, all the copolymers self-assembled into simple vesicles. With increasing the polymer concentration, large compound vesicles were formed. The photo-sensitive properties of the formed aggregates were also studied. Upon irradiation with a polarized light, the aggregates were elongated. Large compound vesicles were found to deform into compact spindles with a very large axial ratio.

Soft Matter published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C18H15N3O3, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xie, He-Lou published the artcileControlling domain orientation of liquid crystalline block copolymer in thin films through tuning mesogenic chemical structures, Related Products of esters-buliding-blocks, the publication is Journal of Polymer Science, Part B: Polymer Physics (2017), 55(6), 532-541, database is CAplus.

Controlling the macroscopic orientation of nanoscale periodic structures of amphiphilic liquid crystalline block copolymers (LC BCPs) is important to a variety of tech. applications (e.g., lithium conducting polymer electrolytes). To study LC BCP domain orientation, a series of LC BCPs containing a poly(ethylene oxide) (PEO) block as a conventional hydrophilic coil block and LC blocks containing azobenzene mesogens is designed and synthesized. LC ordering in thin films of the BCP leads to the formation of highly ordered, microphase-separated nanostructures, with hexagonally arranged PEO cylinders. Substitution on the tail of the azobenzene mesogen is shown to control the orientation of the PEO cylinders. When the substitution on the mesogenic tails is an alkyl chain, the PEO cylinders have a perpendicular orientation to the substrate surface, provided the thin film is above a critical thickness value. In contrast, when the substitution on the mesogenic tails has an ether group the PEO cylinders assemble parallel to the substrate surface regardless of the film thickness value. © 2017 Wiley Periodicals, Inc.J. Polym. Sci., Part B: Polym.Phys. 2017.

Journal of Polymer Science, Part B: Polymer Physics published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C15H21BO2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Qiu, Nannan published the artcileA photo- and thermo-responsive star-shaped diblock copolymer with a porphyrin core prepared via consecutive ATRPs, Safety of 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, the publication is RSC Advances (2016), 6(53), 47912-47918, database is CAplus.

A star-shaped and diblock copolymer poly(6-[4-(4-methoxyphenylazo)phenoxy]hexylmethacrylate)s-b-poly(N-isopropylacrylamide)s with a zinc-porphyrin core (PAzo-b-PNIPAM) is synthesized via consecutive atom transfer radical polymerizations (ATRPs). The synthesis involves the preparation of the intermediate poly(6-[4-(4-methoxyphenylazo)phenoxy]hexylmethacrylate) with a zinc-porphyrin core (por-PAzo) via ATRP, and then por-PAzo is used as a macroinitiator to polymerize N-isopropylacrylamide (NIPAM) via ATRP to gain PAzo-b-PNIPAM. The structures of the target products are characterized by FT-IR, ¹H NMR and UV-vis spectra, and the polydispersity index (PDI) indicates that the mol. weight distribution is narrow and the polymerization is well controlled. Furthermore, the photo- and thermo-responsive properties are also investigated in detail, which demonstrate that the star-shaped diblock copolymer PAzo-b-PNIPAM has a potential application in targeted photodynamic therapy and photo-electro informational storage.

RSC Advances published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C23H28N2O4, Safety of 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xue, Xiaoqiang published the artcilePreparation and characterization of thermal- and light-triggered self-healing azobenzene polymer, Recommanded Product: 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, the publication is Polymers for Advanced Technologies (2022), 33(4), 1328-1340, database is CAplus.

Both temperature- and light-triggered self-healing azobenzene polymer was successfully synthesized via radical copolymerization of 4-(furan-maleimide ethyl) Me methacrylate (MMA-FMI), 4′-(oxyhexyl methacrylate)-4-(oxyfuran-2-carbomethoxy) azobenzene (MMA-FAzo) and 6-(4′-methoxy-4-oxyazobenzene)-hexyl methacrylate at 50°C. The structure of the polymer was characterized by proton NMR (¹H-NMR) spectroscopy, Fourier transform IR spectroscopy, and gel permeation chromatog. Interestingly, furan and maleimide thermally reversible groups were introduced into the polymer. After the furan rings on the MMA-FMI were removed at high temperatures, the exposed maleimide groups were further added with the furan rings on the MMA-FAzo to form a crosslinked network. The crosslinked polymer film was still soluble in the anisole after heating, which could further illustrate the thermal reversibility of the polymer film and realized the recyclability and reworkability of the side-chain azobenzene polymer. ¹H-NMR could prove that the crosslinked polymer was completely decrosslinked and the polymer was thermoreversible. UV-visible (UV-Vis) absorption spectra showed rapid photoisomerization of the polymer, and surface-relief grating formed on the crosslinked PAzo film was also investigated using illumination from a linearly polarized Kr⁺ laser beam. The surface modulation depth and grating spacing were about 149 nm, and 1.7μm, resp. What is more, the polarized light microscopy showed that the crosslinked polymer film could be self-repaired under the combined action of UV light and heating.

Polymers for Advanced Technologies published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C12H9N3O4, Recommanded Product: 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Zhijie published the artcileLigand-Directed Reticular Synthesis of Catalytically Active Missing Zirconium-Based Metal-Organic Frameworks, Product Details of C22H23BO4, the publication is Journal of the American Chemical Society (2019), 141(31), 12229-12235, database is CAplus and MEDLINE.

The ligand-directed reticular syntheses and isoreticular expansion of Zr-based metal-organic frameworks (Zr-MOFs) with the edge-transitive alb net from 12-connected hexagonal-prismatic Zr₆ nodes and 6-connected trigonal-prismatic linkers, i.e., microporous NU-1600, mesoporous NU-1601, and mesoporous NU-1602, are reported. These Zr-MOFs exhibit remarkable activities toward the destruction of a nerve agent (soman) and a nerve agent simulant (DMNP). Crystallog. data are given.

Journal of the American Chemical Society published new progress about 1448637-05-5. 1448637-05-5 belongs to esters-buliding-blocks, auxiliary class Alkynyl,Boronic acid and ester,Benzene,Ester,Boronate Esters,Boronic Acids,Boronic acid and ester,, name is Methyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)benzoate, and the molecular formula is C22H23BO4, Product Details of C22H23BO4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zang, Minghui published the artcileStudy on the synthesis, self-assembly and responsive behavior of azobenzene triblock copolymers, COA of Formula: C23H28N2O4, the publication is Zhongguo Keji Lunwen (2014), 9(6), 648-653, database is CAplus.

A new triblock copolymer poly(ethylene oxide)monomethyl ether-b-poly(acrylic aid)-b-poly[6-(4-methoxy-azobenzene-4′-oxy)hexyl methylacrylic acid] was synthesized by the atom transfer radical polymerization (ATRP) method. The self-assembly behaviors in aqueous media, pH value and photo-sensitive properties of this copolymer were studied by the means of transmission electron microscopy (TEM), SEM (SEM), laser light scattering (LLS) and UV-Vis spectrophotometer. It was found that the copolymer could self-assemble into vesicle structure. With decreasing the pH value, the particle size of the micelles increased sharply obviously bigger when pH<3.4; however, there was not significant change for the particle size of micelles when pH>3.4. Under the irradiation of polarized light, the aggregates were elongated with increasing the irradiation time.

Zhongguo Keji Lunwen published new progress about 135529-02-1. 135529-02-1 belongs to esters-buliding-blocks, auxiliary class azo,Alkenyl,Benzene,Ester,Ether, name is 6-(4-((4-Methoxyphenyl)diazenyl)phenoxy)hexyl methacrylate, and the molecular formula is C14H28O5S, COA of Formula: C23H28N2O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Feng, Pengju published the artcileAccess to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines, SDS of cas: 1448637-05-5, the publication is Chemical Science (2016), 7(1), 424-429, database is CAplus and MEDLINE.

A scalable and operationally simple protocol for regioselective trifluoromethoxylation of a wide range of functionalized pyridines I [R = 5-Br-6-OMe, 6-(1H-Benzo[d]imidazol-1-yl), 6-(1H-pyrazol-1-yl), etc.; R¹ = OMe, Me; X = OH; Y = H] and pyrimidines II [R² = (2-(Thiazol-4-yl)-1H-benzo[d]imidazol-1-yl), 2-OMe, 4-Cl-3,5-(Me)₂-OC₆H₂, etc.; W = OH; Z = H] under mild reaction conditions is presented. The trifluoromethoxylated products I [X = H; Y = 2-OCF₃, 4-OCF₃] and II [W = H; Z = OCF₃] are useful scaffolds that can be further elaborated by amidation and palladium-catalyzed cross coupling reactions. Mechanistic studies suggest that a radical O-trifluoromethylation followed by the OCF₃ -migration reaction pathway is operable. The unique properties of the OCF₃ group and the ubiquity of pyridine and pyrimidine in biol. active mols. and functional materials, trifluoromethoxylated pyridines I [X = H; Y = 2-OCF₃, 4-OCF₃] and pyrimidines II [W = H; Z = OCF₃] could serve as valuable building blocks for the discovery and development of new drugs, agrochems., and materials.

Chemical Science published new progress about 1448637-05-5. 1448637-05-5 belongs to esters-buliding-blocks, auxiliary class Alkynyl,Boronic acid and ester,Benzene,Ester,Boronate Esters,Boronic Acids,Boronic acid and ester,, name is Methyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethynyl)benzoate, and the molecular formula is C22H23BO4, SDS of cas: 1448637-05-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics