Tag: M.W=300-350

Zhao, Qin published the artcileEffect of different boiling methods on flavor components of chicken skeleton soup, COA of Formula: C20H40O2, the publication is Shipin Gongye Keji (2015), 36(7), 314-319, database is CAplus.

The effect of atm. and high-pressure boiling method on amino acids of chicken skeleton soup was analyzed, and the volatile aromatic compounds were extracted by sold-phase micro-extraction (SPME) and analyzed by GC/MS. Results showed that high-pressure boiling had a significant effect on the content of amino acids and free amino acids (p < 0.05). Sixty-two and 54 kinds of volatile aromatic components were identified in high-pressure boiling and atm. boiling chicken skeleton soup resp. The varieties of volatile aromatic components in two kinds of chicken skeleton soups were similar. However, the contents of these various aromatic components were different. There was no significant difference on sensory evaluation of the two kinds of chicken skeleton soup. High-pressure boiling was a viable boiling process.

Shipin Gongye Keji published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C18H34N4O5S, COA of Formula: C20H40O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bovin, N. V. published the artcileIsomerization of (trifluoroacetamido)propyl 2-acetamido-2-deoxy-β-D-galactopyranoside into an α-anomer. A facile synthesis of artificial T-antigen, Safety of (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, the publication is Bioorganicheskaya Khimiya (1986), 12(4), 533-8, database is CAplus and MEDLINE.

β-Glycoside I [R = O(CH₂)₃NHAc, R¹ = H], prepared by glycosidation of I (R = H, R¹ = Cl) with HO(CH₂)₃NHAc in the presence of Hg(CN)₂, was isomerized by BF₃.Et₂O to give 50-60% α-anomer I [R = H, R¹ = O(CH₂)₃NHAc] (II) and oxazoline III. α-Anomer II was converted to benzylidene derivative IV (R = H) which was glycosidated by acetobromogalactose to give 50% IV (R = 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl), followed by deacetylation to give bioside V, the precursor for artificial T-antigen.

Bioorganicheskaya Khimiya published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, Safety of (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Shihai published the artcileStudy on chemical constituents of the soft coral Sinularia inexplicita. I. Elucidation of structure of hydroxyl compound, Computed Properties of 110-34-9, the publication is Jinan Daxue Xuebao, Ziran Kexue Yu Yixueban (1997), 18(5), 63-67, database is CAplus.

The soft coral Sinularia inexplicita collected from the South China Sea was studied chromatog., and 3 secondary metabolites were found. The spectral data and elemental anal. showed that the structures of the metabolites were gorgosterol, batylalc., and iso-Bu palmitate.

Jinan Daxue Xuebao, Ziran Kexue Yu Yixueban published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C6H12Br2, Computed Properties of 110-34-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ni, Zihao published the artcileReaction kinetics analysis of branched-chain alkyl esters of palmitic acid and cold flow properties, Recommanded Product: Isobutyl palmitate, the publication is Renewable Energy (2020), 147(Part_1), 719-729, database is CAplus.

Preparation of Me palmitate, iso-Pr palmitate, iso-Bu palmitate, and isoamyl palmitate was carried out using pyridine Bu bisulfate ionic liquid as catalyst in a self-designed reactor to catalyze esterification reaction of palmitic acid with methanol, isopropanol, isobutanol, and isoamyl alc., resp. According to the single-factor exptl. results, an orthogonal test of four factors and three levels was carried out for branched-chain alkyl esters of palmitic acid under different reaction time, reaction temperature, and catalyst dosage. Verification test was conducted under the optimal conditions, and the conversion in all the cases was up to 97%. Anal. of the reaction kinetics of Me palmitate, iso-Pr palmitate, iso-Bu palmitate, and isoamyl palmitate was carried out by the integral method. Reaction order, frequency factor, activation energy, and reaction kinetic model were determined Compared to Me palmitate, the kinematic viscosity of the branched-chain alkyl esters of palmitic acid was slightly higher; however, the solidifying point (SP) and cold filter plugging point (CFPP) decreased with increasing degree of branched-chain. The CFPP reduced by up to 15°C. Therefore, the use of branched-chain alc. instead of methanol ester exchange descaling method can effectively reduce the SP and CFPP of biodiesel to improve its cold flow properties.

Renewable Energy published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C20H40O2, Recommanded Product: Isobutyl palmitate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Prakash, Thazha P. published the artcileComprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes, Quality Control of 10378-06-0, the publication is Journal of Medicinal Chemistry (2016), 59(6), 2718-2733, database is CAplus and MEDLINE.

The comprehensive structure-activity relationships of triantennary GalNAc conjugated ASOs for enhancing potency via ASGR mediated delivery to hepatocytes is reported. Seventeen GalNAc clusters were assembled from six distinct scaffolds and attached to ASOs. The resulting ASO conjugates were evaluated in ASGR binding assays, in primary hepatocytes, and in mice. Five structurally distinct GalNAc clusters were chosen for more extensive evaluation using ASOs targeting SRB-1, A1AT, FXI, TTR, and ApoC III mRNAs. GalNAc-ASO conjugates exhibited excellent potencies (ED₅₀ 0.5-2 mg/kg) for reducing the targeted mRNAs and proteins. This work culminated in the identification of a simplified tris-based GalNAc cluster (THA-GN3), which can be efficiently assembled using readily available starting materials and conjugated to ASOs using a solution phase conjugation strategy. GalNAc-ASO conjugates thus represent a viable approach for enhancing potency of ASO drugs in the clinic without adding significant complexity or cost to existing protocols for manufacturing oligonucleotide drugs.

Journal of Medicinal Chemistry published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, Quality Control of 10378-06-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Saneyoshi, Hisao published the artcileConjugatable and Bio-reduction Cleavable Linker for the 5′-Functionalization of Oligonucleotides, SDS of cas: 10378-06-0, the publication is Journal of Organic Chemistry (2017), 82(3), 1796-1802, database is CAplus and MEDLINE.

An efficient conjugate and bioreduction cleavable linker was designed and synthesized for the 5′-terminal ends of oligonucleotides. A phosphoramidite reagent bearing this linker was successfully applied to solid phase synthesis and incorporated at the 5′-terminal ends of oligonucleotides. The controlled pore glass (CPG)-supported oligonucleotides were subsequently conjugated to a diverse range of functional mols. using a CuAAC reaction. The synthesized oligonucleotide conjugates were then cleaved using a nitroreductase/NADH bioreduction system to release the naked oligonucleotides.

Journal of Organic Chemistry published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, SDS of cas: 10378-06-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zou, Shuping published the artcileProduction and characterization of bio-oil from hydrothermal liquefaction of microalgae Dunaliella tertiolecta cake, Recommanded Product: Isobutyl palmitate, the publication is Energy (Oxford, United Kingdom) (2010), 35(12), 5406-5411, database is CAplus.

Renewable fuels are major alternatives to conventional fossil fuels. Biomass in the form of agricultural and industrial residues is fast becoming popular among new renewable energy sources. Hydrothermal liquefaction can thermochem. convert biomass residues into bio-oil. This work investigates the hydrothermal liquefaction of microalgae Dunaliella tertiolecta cake under various liquefaction temperatures, holding times, and catalyst dosages. A maximum bio-oil yield of 25.8% is obtained at a reaction temperature of 360 °C and a holding time of 50 min using 5% Na₂CO₃ as a catalyst. The various phys. and chem. characteristics of bio-oil obtained under the most suitable conditions are determined, and a detailed chem. compositional anal. of bio-oil is performed using an elemental analyzer, Fourier transform-IR spectroscopic anal. (FT-IR), and gas chromatog.-mass spectrometry (GC-MS). The bio-oil is composed of fatty acids, fatty acid Me esters, ketones, and aldehydes. Its empirical formula is CH_1.44O_0.29N_0.05, and its heating value is 30.74 MJ/kg. The bio-oil product is a possible eco-friendly green biofuel and chem.

Energy (Oxford, United Kingdom) published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C15H20BNO3, Recommanded Product: Isobutyl palmitate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Ping published the artcileConsumer preference of Chinese traditional fermented fava pastes, HPLC of Formula: 110-34-9, the publication is International Journal of Food Properties (2018), 21(1), 2469-2490, database is CAplus.

The present study was designed to investigate the consumer preference and the quality attributes of five brands of Chinese traditional first-grade fava pastes, following which their quality differences were evaluated in order to identify the key drivers or factors, which can be applied to explain the behavior of consumer preferences. Consumers ranked these samples based on the 9-point method. An obvious preference for sample P1 was observed with 35% of participants settling on extremely liked option, giving the said sample the highest overall preference score of 7.8 ± 0.2. Further sensory and physicochem. properties, and volatiles were conducted to identify the major drivers of the consumer behavior. Sensory evaluation showed that sample P1 also produced the highest overall sensory score (85 ± 3). Though all the samples exhibited similar physicochem. attributes, significant differences were observed in the species and the concentration of volatile compounds Accordingly, the content of free amino acids (FAAs) and low-mol.-weight (MW) fraction (≤5 kDa) represented the trend that fell in line with sensory score. PLS2 correlation anal. indicated that physicochem. indexes and volatiles could be used to explain the consumer preference, which was likely to be synergistically affected by FAAs, protein, amino nitrogen, dietary fiber, Ca, P, Fe, δ-Ε, and some volatiles, especially the pos. drivers of FAAs and low MW proportion to sample P1. The work would not only provide valuable information for grading of fava pastes in the industry but also guide actual producing toward the expectation of consumers, especially increasing those pos. drivers.

International Journal of Food Properties published new progress about 110-34-9. 110-34-9 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester, name is Isobutyl palmitate, and the molecular formula is C20H40O2, HPLC of Formula: 110-34-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nair, Jayaprakash K. published the artcileMultivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing, Application In Synthesis of 10378-06-0, the publication is Journal of the American Chemical Society (2014), 136(49), 16958-16961, database is CAplus and MEDLINE.

Conjugation of small interfering RNA (siRNA) to an asialoglycoprotein receptor ligand derived from N-acetylgalactosamine (GalNAc) facilitates targeted delivery of the siRNA to hepatocytes in vitro and in vivo. The ligands derived from GalNAc are compatible with solid-phase oligonucleotide synthesis and deprotection conditions, with synthesis yields comparable to those of standard oligonucleotides. S.c. (SC) administration of siRNA-GalNAc conjugates resulted in robust RNAi-mediated gene silencing in liver. Refinement of the siRNA chem. achieved a 5-fold improvement in efficacy over the parent design in vivo with a median ED (ED₅₀) of 1 mg/kg following a single dose. This enabled the SC administration of siRNA-GalNAc conjugates at therapeutically relevant doses and, importantly, at dose volumes of ≤1 mL. Chronic weekly dosing resulted in sustained dose-dependent gene silencing for over 9 mo with no adverse effects in rodents. The optimally chem. modified siRNA-GalNAc conjugates are hepatotropic and long-acting and have the potential to treat a wide range of diseases involving liver-expressed genes.

Journal of the American Chemical Society published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, Application In Synthesis of 10378-06-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yamazaki, Tatsumi published the artcileAmino sugars. 127. The synthesis of uridine diphosphate N-acetylhexosamines and uridine 5′-(2-acetamido-2-deoxy-α-D-mannopyranosyluronic acid diphosphate), Formula: C14H19NO8, the publication is Canadian Journal of Chemistry (1981), 59(15), 2247-52, database is CAplus.

2-Methyl-(2-acetamido-3,4,6-trio-O-acetyl-1,2-dideoxy-β-D-mannopyrano)-[2,1-d]-2-oxazoline was efficiently converted into 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-mannopyranosyl phosphate (I), by treatment with dibenzyl phosphate, followed by catalytic hydrogenolysis of the benzyl groups. Similarly, 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glucopyranosyl phosphate and -galactopyranosyl phosphate were synthesized from the resp. peracetyl oxazolines. In each case, the procedures for preparing the oxazoline, and conversion into the glycosyl phosphate, were modified to give high yields of pure products. I was coupled with 2′,3′-di-O-acetyluridine 5′-monophosphate by a modification of the mixed anhydride procedure, to give 2′,3′-di-O-acetyluridine 5′-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-mannopyranosyl diphosphate), which was readily purified by preparative TLC and O-deacetylated to give uridine diphosphate N-acetylmannosamine (II) in high yield. Similarly, uridine 5′-(2-acetamido-2-deoxy-α-D-glucopyranosyl- and -galactopyranosyl diphosphates) were synthesized by rapid, efficient procedures, not involving ion-exchange chromatog. II was converted into mannopyranosyluronic acid III, required for biosynthetic studies, without the preparation of a special Pt catalyst. All the synthetic uridine diphosphate sugars were characterized by optical rotation, ¹H NMR spectrum, and elemental anal.

Canadian Journal of Chemistry published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C25H34N4O2S, Formula: C14H19NO8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics