Tag: M.W=200-250

Subchev, M. published the artcileInhibitors for Autographa gamma L.(Lep., Noctuidae) sex pheromone, Category: esters-buliding-blocks, the publication is Journal of Applied Entomology (1987), 104(4), 425-9, database is CAplus.

The effect of 14 compounds related to (Z)-7-dodecenyl acetate on its attractiveness to A. gamma males was investigated in the field. The inhibitory effect of (Z)-5-decenyl acetate and (Z)-9-tetradecenyl acetate was ascertained and the inhibitory effect of (Z)-5- and (Z)-9-dodecenyl acetate was established for the first time.

Journal of Applied Entomology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C13H15NO6S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Schmidt-Busser, Daniela published the artcileIdentification of host-plant chemical stimuli for the European grape berry moth Eupoecilia ambiguella, Application In Synthesis of 16974-11-1, the publication is Physiological Entomology (2011), 36(2), 101-110, database is CAplus.

The present study aims to identify host-plant stimuli for the European grape berry moth Eupoecilia ambiguella, a major pest of vine in Europe. Headspace volatiles from Vitis vinifera L. cv. Pinot Noir, Vitis vinifera subsp. sylvestris, and 5 other host-plant species comprising 5 different families are analyzed by gas chromatog. linked to electroantennogram (EAG) recording from male E. ambiguella antennae and by gas chromatog.-mass spectrometry. This procedure identifies 32 EAG-active compounds, among them the aliphatic compounds 1-hexanol, (Z)-3-hexenol, (Z)-3-hexenyl acetate, and 1-octen-3-ol; the terpenes limonene, β-caryophyllene, and (E)-4,8-dimethyl-1,3,7-nonatriene; and the aromatic compounds benzaldehyde and Me salicylate. Male and female E. ambiguella show similar EAG response amplitudes to individual chem. stimuli and also to mixtures of plant volatiles, as represented by essential oils from 10 other plant species. This possibly indicates a common role for plant compounds in the sensory ecol. of the 2 sexes of E. ambiguella.

Physiological Entomology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Application In Synthesis of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Siu, Lillian L. published the artcileActivity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units, Recommanded Product: (Pivaloyloxy)methyl butyrate, the publication is Investigational New Drugs (1998), 16(2), 113-119, database is CAplus and MEDLINE.

The anti-proliferative effects of pivaloyloxymethyl butyrate (AN-9), a butyric acid (BA) derivative with potent tumor-differentiating properties both in vitro and in vivo, was evaluated against colorectal, breast, lung, ovarian, renal cell, bladder, and other types of tumor colony-forming units in a human tumor cloning assay. A total of 76 evaluable specimens were exposed to AN-9 continuously, 48 of these were also exposed to BA continuously for direct comparison of the two agents, and 20 specimens were exposed to AN-9 for two hours. An in vitro inhibitory response was defined as a â‰?50% decrease in tumor colony formation in treated cells compared to untreated controls. Superior anti-tumor activity was observed with the continuous exposure to AN-9 (39% in vitro response at 100 μM and 70% at 200 μM) than with the two-hour exposure (20% at 100 μM and 25% at 200 μM). At a continuous concentration of 200 μM, AN-9 demonstrated greater tumor-specific activity than BA against melanoma (100% vs. 67%), ovarian (67% vs. 40%), breast (63% vs. 0%), non-small cell lung (60% vs. 10%), and colorectal tumor colony-forming units (62% vs. 20%). AN-9 is a novel differentiating agent with activity against colony-forming units derived from a variety of primary human tumors, including those that are considered relatively chemoresistant, and may thus provide a therapeutic alternative or addition to standard cytotoxic agents, if appropriate drug concentrations can be achieved in patients.

Investigational New Drugs published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C17H14F3N3O2S, Recommanded Product: (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lebedeva, K. V. published the artcileIsolation, identification, and synthesis of pheromone components of a Tashkent population of cutworm (Mamestra suasa), Product Details of C14H26O2, the publication is Agrokhimiya (1990), 115-25, database is CAplus.

Major constituents of the volatile fraction of the M. suasa pheromone were decanal, dodedecenyl acetate, tridecanol, hexadecanol, and Z-11-hexadecenyl acetate (I) (1.66:1.00:1.34:0.01:176). I was also the main component of leachates from female glands. After the removal of the volatile fraction the electroantennog.-active fraction of the glands contained Z–11-hexadecenal, I, hexadecanyl acetate, octadecanal, Z-6,Z-11-hexadecadienal, and Z-6,Z-11-hexadecadienyl acetate (1.5:742.5:123:100:1:3). Thus, only I was common for all the 3 sources of the pheromone. It was used as the main component of attractants tested in the Asian and European USSR. I + Z-11-hexadecenal (100:10) was especially effective in the Voronezh area in summer, I + hexadecanyl acetate (200:20) and several other compounds were effective in the Tashkent area in spring. Different combinations were effective in the Issyk-Kul area in spring and in summer. None of these mixtures had an adequate selectivity.

Agrokhimiya published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Product Details of C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Greenway, A. R. published the artcileCompounds modifying the activity of two sex attractants for males of the pea moth, Cydia nigricana (F.), Quality Control of 16974-11-1, the publication is Journal of Chemical Ecology (1982), 8(2), 397-408, database is CAplus and MEDLINE.

(E)-10-Dodecen-1-yl acetate (R10-12:Ac) [112-42-5] and (E,E)-8,10-dodecadien-1-yl acetate (E,E8,10-12:Ac) [53880-51-6] are sex attractants for males of the pea moth (C. nigricana). Thirty-two structurally related compounds with chain lengths were exposed with E10-12:Ac or C_9-14 E,E8,10-12:Ac in traps in the field to investigate their influence on the activity of the attractants. Only alcs. and acetates unsaturated at C-8, -9, or -10 greatly influenced moth captures; (Z)- [40642-40-8] and (E)-8-dodecen-1-ol  [42513-42-8] were weak synergists for E10-12:Ac, but not synergists for E,E8,10-12:Ac were found. (Z)- [28079-04-1] And (E)-8-dodecen-1-yl acetate  [38363-29-0] and (E,E)-8,10-dodecadien-1-ol  [33956-49-9] inhibited both E10-12:Ac and E,E8,10-12:Ac, while (E)-10-dodecen-1-ol  [35237-63-9], 10-dodecyn-1-ol  [69221-99-4], (Z) [16974-11-1] and (E)-9-dodecen-1-yl acetate  [35148-19-7], (Z)-10-dodecen-1-yl acetate  [35148-20-0], and undecyl acetate  [1731-81-3] inhibited only the former attractant.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Quality Control of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Jenic, Darko published the artcileReversal of Tetracycline Resistance by Cepharanthine, Cinchonidine, Ellagic Acid and Propyl Gallate in a Multi-drug Resistant Escherichia coli, Application of Propyl 3,4,5-trihydroxybenzoate, the publication is Natural Products and Bioprospecting (2021), 11(3), 345-355, database is CAplus and MEDLINE.

Bacterial resistance to antibiotics is an increasing threat to global healthcare systems. We therefore sought compounds with potential to reverse antibiotic resistance in a clin. relevant multi-drug resistant isolate of Escherichia coli (NCTC 13400). 200 natural compounds with a history of either safe oral use in man, or as a component of a traditional herb or medicine, were screened. Four compounds; ellagic acid, Pr gallate, cinchonidine and cepharanthine, lowered the min. inhibitory concentrations (MICs) of tetracycline, chloramphenicol and tobramycin by up to fourfold, and when combined up to eightfold. These compounds had no impact on the MICs of ampicillin, erythromycin or trimethoprim. Mechanistic studies revealed that while cepharanthine potently suppressed efflux of the marker Nile red from bacterial cells, the other hit compounds slowed cellular accumulation of this marker, and/or slowed bacterial growth in the absence of antibiotic. Although cepharanthine showed some toxicity in a cultured HEK-293 mammalian cell-line model, the other hit compounds exhibited no toxicity at concentrations where they are active against E. coli NCTC 13400. The results suggest that phytochems. with capacity to reverse antibiotic resistance may be more common in traditional medicines than previously appreciated, and may offer useful scaffolds for the development of antibiotic-sensitizing drugs.

Natural Products and Bioprospecting published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Application of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Van Kerckhoven, Christel published the artcileDithiocarbamate telechelic polymers: synthesis and block copolymerization, Related Products of esters-buliding-blocks, the publication is Makromolekulare Chemie (1991), 192(1), 101-14, database is CAplus.

The iniferter method was studied for the synthesis of polyvinyl block copolymers of relatively low mol. weight using tetramethylthiuram disulfide (I) and benzyl diethyldithiocarbamate (II) as initiator. Considering the low quantum yield of dissociation (ϕ_d) of I (2.5·10^-3 in cyclohexane), I was used as a thermal initiator (95°) for the synthesis of dithiocarbamate-polystyrene telechelics. ¹³C-NMR anal. of these telechelics showed 2 ¹³C=S signals corresponding to 2 different end groups: Et₂NCSS₂CHPhCH₂– and Et₂NCSS₂CH₂CHPh-. Several styrene polymerizations were also carried out in the presence of AIBN as thermal initiator and I as chain-transfer agent. Depending on the AIBN-I mole ratio, mono- and difunctional telechelics were formed, as evidenced by NMR anal. These telechelics were used for the photochem. initiations of Et acrylate (III), acrylic acid, and Me methacrylate (IV). It was assumed that ϕ_d of the dithiocarbamate end group was equal to that of II (0.06). Nonfunctional polymers were also prepared, either photochem. by dissociation of II, or thermally in presence of AIBN and II as transfer agent. They were used for block copolymerization with IV. Inversely, telechelics were prepared in a first step; in this case ϕ_d = 0.026. They were then used for the polymerization of III. The block copolymers were fractionated; their composition and mol. weights were determined by ¹H NMR and gel-permeation chromatog., resp.

Makromolekulare Chemie published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C17H16O2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Loefstedt, Christer published the artcileSex pheromone components of the turnip moth, Agrotis segetum: chemical identification, electrophysiological evaluation and behavioral activity, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Journal of Chemical Ecology (1982), 8(10), 1305-21, database is CAplus and MEDLINE.

Anal. of female abdominal tips of A. segetum by gas chromatog.-mass spectrometry showed the presence of 13 aliphatic acetates and alcs. (Z)-7-Dodecenyl acetate was the main component in the extracts (� ng/female). (Z)-9-Tetradecenyl acetate and (Z)-7-dodecenol were present to the extent of 49 and 19%, resp., of the main component. Minor components were identified as decyl acetate, (Z)-5-decenyl acetate, dodecyl acetate, (Z)-9-dodecenyl acetate, tetradecyl acetate, a tetradecenyl acetate, hexadecyl acetate, a hexadecenyl acetate, (Z)-5-decenol, and (Z)-9-tetradecenol. Tested by electroantennog., (Z)-5-decenyl acetate evoked the highest response among pheromone candidates, followed by (E)-5-decenyl acetate and (Z)-7-dodecenyl acetate. Single-cell recordings from 100 male antennal sensilla trichodea revealed receptor cells highly sensitive to (Z)-5-decenyl, (Z)-7-dodecenyl, (Z)-8-dodecenyl, and (Z)-9-tetradecenyl acetates as well as (Z)-5-decenol. The (Z)-5-decenyl, (Z)-7-dodecenyl, and (Z)-9-tetradecenyl acetate receptors were activated also by female extracts When tested in a tube olfactometer, a blend of decyl, (Z)-5-decenyl, (Z)-7-dodecenyl, and (Z)-9-tetradecenyl acetates evoked the same male response as did female glands. Tested in the field, this blend was more attractive than virgin females.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Loefstedt, Christer published the artcileSex pheromone of the cone pyralid Dioryctria abietella, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Entomologia Experimentalis et Applicata (1983), 34(1), 20-6, database is CAplus.

Gas chromatog. analyses coupled with electroantennog. detection indicated that (Z,E)-9,11-tetradecadienyl acetate (I) is a pheromone component of D. abietella. Gas chromatog. and mass spectrometric analyses confirmed the presence of a tetradecadienyl acetate with mass spectrum and retention index identical to those of I. A receptor cell sensitive to both I and the female extract was identified on the male antenna. An addnl. receptor cell sensitive to (Z)-9-tetradecenyl acetate and (Z,E)-9,12-tetradecadienyl acetate was found on the male antenna but was not activated by the female extract In the field, I presented alone attracted significant numbers of male D. abietella. Addition of (Z)-9-tetradecenyl acetate inhibited the attraction of males to traps.

Entomologia Experimentalis et Applicata published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guntreddi, Tirumaleswararao published the artcileDirect conversion of methylarenes into dithiocarbamates, thioamides, and benzyl esters, Related Products of esters-buliding-blocks, the publication is Tetrahedron (2014), 70(25), 3887-3892, database is CAplus.

A new strategy for the synthesis of a variety of dithiocarbamates and thioamides was developed employing inexpensive and readily available methylarenes under metal-free and solvent-free conditions. The approach offers a one-pot procedure and was also extended to the synthesis of a diverse range of benzyl esters. The structures of the compounds were established on the basis of spectroscopic data and confirmed by single crystal x-ray diffraction anal. of 2-chlorobenzyl pyrrolidine-1-carbodithioate (I). The Crystallog. data of I were deposited at the Cambridge Crystallog. Data Center as supplementary publication number CCDC 978710.

Tetrahedron published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics