Tag: M.W=200-250

Otsu, Takayuki published the artcileA model for living radical polymerization, Synthetic Route of 3052-61-7, the publication is Makromolekulare Chemie, Rapid Communications (1982), 3(2), 133-40, database is CAplus.

The polymerization of Me methacrylate  [80-62-6] takes place by living radical homogeneous solution polymerization in the presence of PhN:NCPh₃  [981-18-0] (thermal iniferter) or Et₂NCS₂CH₂Ph [3052-61-7] (photoiniferter). The functionally terminated poly(Me methacrylate) obtained with these iniferters was capable of further polymerization with added monomer.

Makromolekulare Chemie, Rapid Communications published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Synthetic Route of 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nagasawa, Kinzo published the artcileSeparation and detection of carbamates and related compounds on polyamide layers, HPLC of Formula: 3052-61-7, the publication is Journal of Chromatography (1970), 52(3), 453-9, database is CAplus and MEDLINE.

The separation and detection of 22 carbamates and related compounds including insecticidal or herbicidal materials in current use, were investigated on polyamide layers. Suitable solvent systems and the Rf data are reported. A new spray reagent, pinacryptol yellow, was examined for the detection of these compounds and its usability was acertained. A comparison was also made between detection limits by uv absorption on polyamide and silica gel layers, and the superiority of the polyamide layers was confirmed.

Journal of Chromatography published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, HPLC of Formula: 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hu, Jin published the artcileRobust, transparent, and self-healable polyurethane elastomer via dynamic crosslinking of phenol-carbamate bonds, Safety of Propyl 3,4,5-trihydroxybenzoate, the publication is Polymer (2021), 123674, database is CAplus.

Intrinsic self-healing materials designed through the incorporation of noncovalent interactions or dynamic covalent bonds are prized for their ability to recover from mech. damages. However, they often suffer from deteriorated mech. property due to the increased chain mobility. In this work, we reported a high-strength, colorless transparent self-healing polyurethane elastomer through dynamic crosslinking of reversible phenol-carbamate bonds. Tetrabromobisphenol A (TBBPA) and Pr gallate (PG) were used as the dynamic chain extender and dynamic crosslinking agent, resp. They both can be effectively deblocked at mild temperatures ensuring that the self-healing efficiency is not affected by the material formulation. The mech. properties can be tailored in a wide range by varying the crosslink d. and hard segment content, and their combination uniquely determines the material formulation. The phenol-carbamate based polyurethane (PPU) with a hard segment of 60% and a crosslink d. ν of 0.5 mmol cm^-3 exhibited a tensile strength up to 46.4 MPa at the break strain of 615% and displayed high elastic resilience. In the meantime, it could be fully healed (ησ = 93%) with 2 h of heating at 100°C after completely cut off. After recycled three times, it still maintained 80% of its original tensile strength. The structural rigidity of the crosslinker PG and the highly reversible phenol-carbamate bond play a crucial role in strengthening the mech. strength while maintaining the self-healing efficiencies at elevated temperatures This work provides a feasible strategy to prepare mech. robust crosslinked polyurethane elastomer with high self-healing efficiency in a cost-effective manner.

Polymer published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Safety of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Entin-Meer, Michal published the artcileIn vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas, Safety of (Pivaloyloxy)methyl butyrate, the publication is Neuro-Oncology (Durham, NC, United States) (2007), 9(2), 82-88, database is CAplus and MEDLINE.

Histone modification has emerged as a promising approach to cancer therapy. We explored the in vivo efficacy of a butyric acid derivative, pivaloyloxymethyl butyrate (AN-9), for the treatment of gliomas. Relative to control and single-modality treatments, the combination of AN-9 and radiation significantly inhibited tumor growth and prolonged time to failure in mice bearing glioma xenografts. The enhanced response to radiation was accompanied by inhibition of cellular proliferation and by increased phosphorylation of H2AX, implicating DNA double-strand breaks in the antineoplastic effects of AN-9 and radiation. The data suggest that AN-9 in combination with radiation may be an effective therapy for malignant gliomas.

Neuro-Oncology (Durham, NC, United States) published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Safety of (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yang, Gesheng published the artcileInfluences of stabilizers on lyocell spinning dope and fiber properties, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate, the publication is Polymer Testing (2021), 107228, database is CAplus.

To inhibit some side reactions in the production of lyocell fiber, it is usually necessary to add a stabilizer into the spinning dope. In this report, the effects of several stabilizers on the spinning dope are investigated using rheometry, viscometry, and UV spectroscopy, and the resulting lyocell fibers are thoroughly analyzed. The results indicate that 2,4,5,7,8-pentamethyl-4-hydro-1,3-benzodioxin-6-ol (PBD) has the best comprehensive effect among stabilizers used individually, but that butylated hydroxytoluene (BHT) has the least impact on the color of spinning dope and resulting fibers. Overall, compound stabilizers are more effective than individual stabilizers. The compound stabilizer comprising BHT:PBD = 1:1 influenced the color of spinning dope the least, so the obtained fibers had the highest whiteness. The compound stabilizer comprising PG:PBD = 9:1 (PG = Pr gallate) had the most significant stabilizing effect on spinning dope, and the obtained fibers had the greatest breaking strength.

Polymer Testing published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C18H22O4, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhou, Ting published the artcileSynthesis of 4′-alkoxy[1,1′-biphenyl]-4-carboxylic acid lipotripeptides, Application In Synthesis of 50670-76-3, the publication is Yaoxue Shijian Zazhi (2011), 29(1), 17-20, database is CAplus.

4′-Alkoxy[1,1′-biphenyl]-4-carboxylic acid lipotripeptide derivatives were designed as intermediates for the total synthesis of caspofungin-like cyclic lipopeptide antifungal agents. The synthesis of the target compounds was achieved (67.4-80.0%. overall yield) by a five-step sequence using as reactants N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-N⁵-[(phenylmethoxy)carbonyl]-L-ornithyl-O-(1,1-dimethylethyl)-L-seryl-L-proline 1,1-dimethylethyl ester and N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-N⁵-[(phenylmethoxy)carbonyl]-L-ornithyl-O-(1,1-dimethylethyl)-L-threonyl-L-proline 1,1-dimethylethyl ester and 4′-(alkoxy)[1,1′-biphenyl]-4-carboxylic acid 1H-benzotriazolyl esters and the products thus obtained were confirmed by ESI-MS and elemental anal.

Yaoxue Shijian Zazhi published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C7H6O3, Application In Synthesis of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Asano, Akiko published the artcileAscidiacyclamides containing oxazoline and thiazole motifs assume square conformations and show high cytotoxicity, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, the publication is Journal of Peptide Science (2018), 24(10), n/a, database is CAplus and MEDLINE.

Four cyclic octapeptides were designed from ascidiacyclamide [cyclo(-Ile-Oxz-D-Val- Thz-)₂] (ASC, 1) to investigate the effects of oxazoline (Oxz) and thiazole (Thz) rings on the structures and cytotoxicities of the peptides. Cyclo(-Ile-Thz-D-Val-Oxz-)₂ (2) had the same number of Oxz and Thz rings as ASC, but the ring positions were switched. Cyclo(-Ile-Oxz-D-Val-Thz-Ile-Thz-D-Val-Thz-) (3) and cyclo(-Ile-Thz-D-Val-Oxz-Ile-Thz-D-Val-Thz-) (4) contained one Oxz and three Thz rings within the mol. All Oxz rings were substituted with Thz in cyclo(-Ile-Thz-D-Val-Thz-)₂ (5). These analogs had new Oxz and Thz blocks forming the 24-membered ring. Based on CD spectra and X-ray diffraction analyses, the structures of all four analogs were classified as square ASC forms. But the structures of 2 and 5 differed from the original square form of 1, and they showed no cytotoxicity. The structure of 3 was very similar to that of 1, and 3 showed 10 times greater cytotoxicity than 1. Although no definite structure of 4 was obtained, it showed three times greater cytotoxicity than 1. It appears that the position and number of Oxz residues are essential determinants in the structure-cytotoxicity relationship of ASC analogs.

Journal of Peptide Science published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C10H19NO3, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kutsumizu, Shoichi published the artcileSystematic exploitation of thermotropic bicontinuous cubic phase families from 1,2-bis(aryloyl)hydrazine-based molecules, Application In Synthesis of 50670-76-3, the publication is Physical Chemistry Chemical Physics (2018), 20(12), 7953-7961, database is CAplus and MEDLINE.

Rational design of mols. that exhibit a thermotropic bicontinuous cubic (Cub) phase has been earnestly desired. In this work, we describe the suitable selection of a mol. motif that has enabled the systematic exploitation of eight new series of Cub-phase mols. with sym. mol. cores, N-n (1), PB-n (2), S-n (3), and PEB-n (4), and unsym. cores, B-N-n (5), B-PB-n (6), B-S-n (7), and B-PEB-n (8). These eight series all originate from achiral chain-core-chain type rod-like mols. that exhibit two types of Cub phases, an achiral Ia3d phase, and a chiral phase. All the Ia3d phases formed were found to be isomorphous structures, with their cell dimensions being proportional to the core size, and the same was true for the latter chiral phase. We demonstrated that the formation is mainly governed by the segregation between core and alkyl moieties of the mols., and thus, by the weight fraction of the core portion f_core. This work also demonstrates that the central dicarbonylhydrazine linkage bearing intermol. hydrogen bonding ability exhibits a pinning effect that prevents slippage of π-stacks of mols., which is critical for the formation of the two Cub phases that are composed of chiral networks with twisted mol. arrangements. In each series, the emergence of spontaneous chirality formation that occurred in the chiral phase was limited to between 0.36 and 0.50 in the range of f_core. An interesting insight was that the introduced unsymmetry of the mol. core strongly influenced the phase behavior, which lowered the temperature range of Cub phases to around that of the smallest core series B-n, while the high temperature limit (T_c) was roughly proportional to the core size, as determined by the strength of intermol. π-π interactions.

Physical Chemistry Chemical Physics published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Application In Synthesis of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Wanyi published the artcileAnalysis, occurrence, toxicity and environmental health risks of synthetic phenolic antioxidants: A review, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate, the publication is Environmental Research (2021), 111531, database is CAplus and MEDLINE.

A review. The continuous improvement of living standards is related to higher requirements for the freshness and taste of food. For example, synthetic phenolic antioxidants (SPAs) are added to fats and fried foods as food additives to minimize the oxidative rancidity of oils and fats. Hence, the global use of SPAs is increasing year by year. Di-Bu hydroxytoluene is one of the widely used SPAs, often in combination with Bu hydroxyanisole or gallate SPAs. The extensive use of these compounds makes them and their transformation products to be widespread in various environmental matrixes, including indoor dust, wastewater, river water, sewage sludge, and sediment, as well as human samples, such as nails and urine, at concentrations varying from nanogram per g (ng/g) to microgram per g (μg/g). Animal experiments have shown that high-dose SPA exposure is toxic, which may lead to DNA damage and mismatches and the development of cancerous tumors. Since the biosphere shares the same set of genetic codes, humans and animals have many identical or similar feedback mechanisms and information pathways. Therefore, the damage of SPAs to animals may also threaten human health. This review discusses the properties, occurrence, anal., and environmental health risks of typical SPAs, including Bu hydroxyanisole, di-Bu hydroxytoluene, tert-butylhydroquinone, Pr gallate, octyl gallate, and lauryl gallate, used as food additives. In addition, AO2246, which is used in food packaging bags, is also considered. Future research directions on SPAs and their transformation products (TPs) are identified and discussed.

Environmental Research published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C24H12, Recommanded Product: Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ye, Cui published the artcileCu₃(PO4)₂/BiVO₄ photoelectrochemical sensor for sensitive and selective determination of synthetic antioxidant propyl gallate, COA of Formula: C10H12O5, the publication is Analytical and Bioanalytical Chemistry (2022), 414(14), 4139-4147, database is CAplus and MEDLINE.

Abstract: Pr gallate (PG) as one of the most important additives has been widely used to prevent or slow the oxidation of foods in the food industry. In this work, Cu₃(PO₄)₂/BiVO₄ composite is synthesized through two hydrothermal processes. With visible light irradiation, the Cu₃(PO₄)₂/BiVO₄ composites modified PEC platform displays a superior anode photocurrent signal. The PEC sensor showed a wide linear range from 1 x 10^-10 to 1 x 10^-3 mol L^-1 with a detection limit as low as 0.05 x 10^-10 mol L^-1. The Cu₃(PO₄)₂/BiVO₄ photoelectrochem. (PEC) sensor is designed and characterized by electrochem. impedance. Compared with GCE/BiVO₄ and GCE/Cu₃(PO₄)₂, the GCE/Cu₃(PO₄)₂/BiVO₄ has a higher photocurrent response. In addition, the sensor is highly selective for samples containing other antioxidants. Furthermore, the sensor can be used to detect PG in edible oil samples with satisfactory results. The recoveries of Pr gallate in edible oil ranged from 95.5 to 101.8%. The results show that Cu₃(PO₄)₂/BiVO₄ composites can be used to analyze PG in different edible oil samples, which are beneficial for food quality monitoring and reduce the risk of PG overuse in food. Graphical abstract: [graphic not available: see fulltext]

Analytical and Bioanalytical Chemistry published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C11H21BO2Si, COA of Formula: C10H12O5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics