Tag: M.W=150-200

Yang, Tsan Hsi published the artcileReversed-phase high-performance liquid chromatography of C₅ to C₂₀ isoprenoid benzoates and naphthoates, Product Details of C12H14O2, the publication is Methods in Enzymology (1985), 111(Steroids Isoprenoids), 252-63, database is CAplus.

HPLC properties for benzoate and naphthoate esters of linear C_5-20 isoprenoid alcs. are described. All separations were on Waters Radial Pak A columns (C₁₈, 10 μm, 8 mm × 10 cm). Doubly deionized H₂O and MeCN were passed through type HA (0.45-μm) and type FA (0.5-μm) filters, resp., and degassed under vacuum just prior to use. Samples were dissolved in MeCN, and 5-25 μL portions were injected. In general, the capacity factors increased with increases in the number of double bonds, branching, and Z double bond content. The large absorptivities of the aromatic ester moieties provide high sensitivity for UV detection.

Methods in Enzymology published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C40H35N7O8, Product Details of C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yang, Tsanhsi published the artcileInvestigation of isoprenoid benzoates and naphthoates by reversed-phase liquid chromatography. Isocratic elution characteristics of benzoates and naphthoates of C₅-C₂₀ terpenoid alcohols, Application of 3-Methylbut-2-en-1-yl benzoate, the publication is Journal of Chromatography (1984), 121-32, database is CAplus and MEDLINE.

Conditions for derivatization of C₅-C₂₀ isoprenoid alcs. and the reversed-phase liquid chromatog. properties of the corresponding benzoate and naphthoate esters are described. A non-linear response of log k‘ to changes in the composition of the mobile phase was observed on a Radial-Pak C₁₈ column. In general, the capacity factors (k‘) increased with increases in C content and degree of saturation in the hydrocarbon chain, and decreased with increases in branching and Z double bond content. Replacement of a single H in the Me group at C-3 of geranyl benzoate with F had little effect on k‘, while the difluoro- and trifluoromethyl derivatives showed regular increases in k‘. The large extinction coefficients of the aromatic ester moieties, especially the 2-naphthoates, provide high sensitivity of UV detection.

Journal of Chromatography published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C65H82N2O18S2, Application of 3-Methylbut-2-en-1-yl benzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Trejbal, Jiri published the artcileDetermination of Density, Viscosity, and Saturated Vapor Pressure of Various Itaconic Acid Esters, Related Products of esters-buliding-blocks, the publication is International Journal of Thermophysics (2022), 43(4), 51, database is CAplus.

Due to the growing consumption and depletion of fossil resources, researchers are forced to find alternative bio-based resources to produce fine chems. Itaconic acid esters represent an exciting group of substances that could be potentially used in several areas of the chem. industry, such as a replacement of widely used acrylates in the dye industry. Basic properties, such as d., viscosity, and saturated vapor pressure, are crucial for producing these compounds, same as process simulations. Several properties of various itaconates with com. use were studied in this paper. The presented data were exptl. determined and compared to the previously published data. The data were subsequently fitted by a relevant model for each property in Aspen Plus simulation software, and the conformity between the exptl. and calculated data was determined by values of average absolute deviation. The basic knowledge about these phys.-chem. properties will be helpful in future process simulations and development in esters production

International Journal of Thermophysics published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C10H11ClO2S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sobhani, Sara published the artcileA new nanomagnetic Pd-Co bimetallic alloy as catalyst in the Mizoroki-Heck and Buchwald-Hartwig amination reactions in aqueous media, Application of Methyl 3-phenyl-2-propenoate, the publication is Scientific Reports (2021), 11(1), 17025, database is CAplus and MEDLINE.

A Pd-Co bimetallic alloy encapsulated in melamine-based dendrimer supported on magnetic nanoparticles denoted as γ-Fe₂O₃@MBD/Pd-Co was synthesized by a facile co-complexation-reduction method and characterized sufficiently. The catalytic evaluation of γ-Fe₂O₃@MBD/Pd-Co showed promising results in the Mizoroki-Heck and Buchwald-Hartwig amination reactions of various iodo-, bromo- and challenging chloroarenes in aqueous media. The synergetic cooperative effect of both Pd and Co and dispersion of the catalyst in water due to the encapsulation of γ-Fe₂O₃ by melamine-based dendrimer lead to high catalytic performance compared with the monometallic counterparts. The dispersion of the magnetic catalyst also facilitates the recovery and reuse of the catalyst by ten consecutive extraction and final magnetic isolation with no loss of catalytic activity, keeping its structure unaltered.

Scientific Reports published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C8H6ClNO, Application of Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Matic, Tamara published the artcileSr,Mg co-doping of calcium hydroxyapatite: Hydrothermal synthesis, processing, characterization and possible application as dentin substitutes, Product Details of C11H15NO2, the publication is Ceramics International (2022), 48(8), 11155-11165, database is CAplus.

The aim of this study was to investigate the influence of binary Sr, Mg ion-doping compared to the single-ion doping effects on the phase composition and morphol. of hydrothermally obtained calcium hydroxyapatite (HAP) powders and on the phase composition, microstructure, and mech. properties of the sintered materials. Addnl., the focus of this study was to investigate the possible utilization of the binary doped Sr,Mg-HAP compacts as dentin substitutes in restorative dentistry by evaluating their bonding ability with com. available restorative materials using the shear bond strength test (SBS). The hydrothermally obtained mono-doped Mg5 and Sr5 showed the monophasic apatite structure, while in all co-doped samples β-TCP phase was formed, resulting in biphasic calcium phosphate (BCP) powders. It was confirmed that co-doping with Sr and Mg ions led to the thermal stabilization of the β-TCP phase by suppressing the phase transition into α-TCP when sintered at 1200 βC. Moreover, the co-presence of Mg ions significantly improved the hardness of Sr-doped HAP from 3.74 to 5.02 GPa. Sr,Mg-HAP dental inserts were found to achieve sufficient bonding (13.53 MPa) through the micromech. interlocking with Z250 dental composite and Single Bond Universal dental adhesive applied with a total etch approach. The SBS values obtained for the SrMg-HAP insert were similar to the literature data on bonding ability with human dentin, indicating that binary doped Sr,Mg-HAP ceramics present a promising material for application in restorative dentistry as dentin substitutes.

Ceramics International published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C11H15NO2, Product Details of C11H15NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Lei published the artcileCatalyst-Free 1,2-Dibromination of Alkenes Using 1,3-Dibromo-5,5-dimethylhydantoin (DBDMH) as a Bromine Source, Quality Control of 103-26-4, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

A direct 1,2-dibromination method of alkenes is realized using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) as bromine source. This reaction proceeds under mild reaction conditions without the use of catalyst and external oxidant. Various sorts of alkene substrates are transformed into the corresponding 1,2-dibrominated products in good to excellent yields with broad substrate scope and exclusive diastereoselectivity. This method offers a green and practical approach to synthesize vicinal dibromide compounds

Journal of Organic Chemistry published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C6H13I, Quality Control of 103-26-4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gao, Tianfeng published the artcileTargeting dihydrofolate reductase: Design, synthesis and biological evaluation of novel 6-substituted pyrrolo[2,3-d]pyrimidines as nonclassical antifolates and as potential antitumor agents, Related Products of esters-buliding-blocks, the publication is European Journal of Medicinal Chemistry (2019), 329-340, database is CAplus and MEDLINE.

A novel series of 6-substituted pyrrolo[2,3-d]pyrimidines with reversed amide moieties from the lead compound I (R = 4-pyridyl) were designed and synthesized as nonclassical antifolates and as potential antitumor agents. Target compounds II were successfully obtained through two sequential condensation reactions from the key intermediate 2-amino-6-(2-aminoethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one. In preliminary antiproliferation assay, all compounds demonstrated submicromolar to nanomolar inhibitory effects against KB tumor cells, whereas compounds I (R = 2-, 3-, 4-pyridyl) also exhibited nanomolar antiproliferative activities toward SW620 and A549 cells. In particular, compounds I (R = 2-, 3-, 4-pyridyl) were significantly more potent than the pos. control methotrexate (MTX) and pemetrexed (PMX) to A549 cells. The growth inhibition induced cell cycle arrest at G1-phase with S-phase suppression. Along with the results of nucleoside protection assays, inhibition assays of dihydrofolate reductase (DHFR) clearly elucidated that the intracellular target of the designed compounds was DHFR. Mol. modeling studies suggested two binding modes of the target compounds with DHFR.

European Journal of Medicinal Chemistry published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Huang, Qi published the artcileSystematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis, Quality Control of 103-26-4, the publication is Biomedicine & Pharmacotherapy (2021), 111735, database is CAplus and MEDLINE.

Bark is the traditional medicinal component of Eucommia ulmoides Oliver (E. ulmoides). However, the demand for E. ulmoides medicinal materials seriously limits their sustainability. To alleviate resource constraints, the bioactivity of E. ulmoides leaves and its pharmacodynamic basis were investigated. In the present study, extracts of E. ulmoides leaves were found to display potential renal protective properties in rat glomerular mesangial (HBZY-1) cells treated with high levels of glucose, suggesting that they possess potential factors capable of treating diabetic nephropathy. Ultra-performance liquid chromatog. tandem quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS) was used to comprehensively characterize the chem. components of E. ulmoides leaves. A total of 83 possible chem. components, including 12 iridoids, 13 flavonoids, 14 lignans, 20 phenylpropanoids, 14 phenolic acids, and 10 addnl. components, were identified in E. ulmoides leaves. Network pharmacol. was used for a preliminary exploration of the potential mechanism of action of renal protection afforded by E. ulmoides leaves towards diabetic nephropathy. The network pharmacol. results were verified using a series of biol. experiments The present study provided the basis for the comprehensive development and utilization of E. ulmoides leaves and the discovery of potential drugs.

Biomedicine & Pharmacotherapy published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Quality Control of 103-26-4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ochiai, Shiho published the artcileSynthesis of Benzylidenesuccinates through Rhodium(III)-Catalyzed C-H Alkenylation with Itaconate, Quality Control of 617-52-7, the publication is Asian Journal of Organic Chemistry (2022), 11(2), e202100774, database is CAplus.

The dehydrogenative coupling of aromatic amides, e.g., (1-methyl-1H-indol-2-yl)-1-pyrrolidinylmethanone with di-Me itaconate proceeds smoothly under rhodium catalysis through ortho C-H bond cleavage directed by their amide group to produce benzylidenesuccinates, e.g., I. Aromatic carboxylic acids, e.g., 2-thiophenecarboxylic acid including benzoic and phthalic acids also couple with the itaconate to give 1 : 2 coupling products, e.g., II predominantly. Benzylidenesuccinic acid derivatives have been known to show various biol. activities. These reactions provide easy access to the important structures.

Asian Journal of Organic Chemistry published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Quality Control of 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dai, Huimin published the artcileSolvent-Controlled, Tunable β-OAc and β-H Elimination in Rh(III)-Catalyzed Allyl Acetate and Aryl Amide Coupling via C-H Activation, Name: 3-(Methoxycarbonyl)benzoic acid, the publication is Organic Letters (2016), 18(14), 3410-3413, database is CAplus and MEDLINE.

The Heck reaction between arenes and allyl acetate led to cinnamyl derivatives and allyl products depending on the regioselectivity of β-elimination. The regioselectivity can be controlled by the solvent in the Rh(III)-catalyzed arene-allyl acetate coupling via C-H activation: (1) in THF, cinnamyl derivatives via β-H elimination were generated; (2) in MeOH, allyl products via β-OAc elimination were produced. Both routes have advantages such as excellent γ-selectivity toward allyl acetate, good to excellent yields, and broad substrate scope.

Organic Letters published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Name: 3-(Methoxycarbonyl)benzoic acid.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics