Tag: M.W=100-150

Chen, Guitang published the artcileVolatile components of white Hypsizygus marmoreus detected by electronic nose and HS-SPME-GC-MS: Influence of four drying methods, Computed Properties of 5340-78-3, the publication is International Journal of Food Properties (2017), 20(12), 2901-2910, database is CAplus.

Four drying methods, viz hot air drying (HD), vacuum drying (VD), microwave-vacuum drying (MVD), and vacuum freeze-drying (FD), were used to dry white Hypsizygus marmoreus (WHM). The volatile and taste components of the dried WHM were comparatively analyzed by electronic nose technol. (E-nose) and head-space solid-phase microextraction combined with gas chromatog.-mass spectrometry (HS-SPME-GS-MS). Principal component anal. (PCA) showed that E-nose could distinguish fresh WHM and four dried products clearly. Dominant volatile components in fresh WHM were found to be 1-octen-3-ol, 3-octanone, and (E)-2-nonenal. However, it was found that the drying methods caused damage to the 8-carbon compounds (C8), especially to 8-carbon alc. greatly. For instance, HD produced more ester materials, MVD yielded more aldehyde compounds, FD brought more hydrocarbon products, and VD produced more ketone substances.

International Journal of Food Properties published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Computed Properties of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wang, Hui published the artcileSelective Coupling of 1,2-Bis-Boronic Esters at the more Substituted Site through Visible-Light Activation of Electron Donor-Acceptor Complexes, Safety of Dimethyl fumarate, the publication is Angewandte Chemie, International Edition (2022), 61(18), e202202061, database is CAplus and MEDLINE.

1,2-Bis-boronic esters are useful synthetic intermediates particularly as the two boronic esters can be selectively functionalized. Usually, the less hindered primary boronic ester reacts, but herein, we report a coupling reaction that enables the reversal of this selectivity. This is achieved through the formation of a boronate complex with an electron-rich aryllithium which, in the presence of an electron-deficient aryl nitrile, leads to the formation of an electron donor-acceptor complex. Following visible-light photoinduced electron transfer, a primary radical is generated which isomerizes to the more stable secondary radical before radical-radical coupling with the arene radical-anion, giving β-aryl primary boronic ester products. The reactions proceed under catalyst-free conditions. This method also allows stereodivergent coupling of cyclic cis-1,2-bis-boronic esters to provide trans-substituted products, complementing the selectivity observed in the Suzuki-Miyaura reaction.

Angewandte Chemie, International Edition published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C3H6O2, Safety of Dimethyl fumarate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhou, Wei published the artcileTetrachlorophthalimides as Organocatalytic Acceptors for Electron Donor-Acceptor Complex Photoactivation, Computed Properties of 624-49-7, the publication is Journal of the American Chemical Society (2022), 144(20), 8914-8919, database is CAplus and MEDLINE.

Herein, the available electron-poor tetrachlorophthalimides I (R = Ph, 2,4,6-trimethylphenyl) can act as effective organocatalytic acceptors to trigger the formation of EDA complexes with a variety of radical precursors not amenable to previous catalytic methods. Excitation with visible light generates carbon radicals under mild conditions. The versatility of this EDA complex catalytic platform allowed to develop mechanistically distinct radical reactions, including in combination with a cobalt-based catalytic system. Quantum yield measurements established that a closed catalytic cycle is operational, which hints at the ability of tetrachlorophthalimides I to readily turn over and govern each catalytic cycle.

Journal of the American Chemical Society published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C19H34ClN, Computed Properties of 624-49-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guo, Xiao-hong published the artcileSynthesis of rufloxacin hydrochloride, Application In Synthesis of 924-99-2, the publication is Zhongguo Yaoye (2008), 17(10), 24-25, database is CAplus.

A method for the synthesis of the title compound [i.e., 9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hydrochloride] is reported here.

Zhongguo Yaoye published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Application In Synthesis of 924-99-2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Whitmore, Frank C. published the artcileAction of primary Grignard reagents on tert-butylacetyl chloride. II, Computed Properties of 5340-78-3, the publication is Journal of the American Chemical Society (1938), 2790-2, database is CAplus.

Addition of EtMgBr to tert-BuCH₂COCl gives tert-BuCH₂CO₂Et(I), 77% of neopentylethylcarbinyl tert-butylacetate, 51% of Et neopentyl ketone and some tert-BuCH₂CO₂H (II). PrMgBr gives I, II, 36.7% of Pr neopentyl ketone, 20% of neopentylpropylcarbinyl tert-butylacetate and dodecenes. BuMgBr gives I, 34% of Bu neopentyl ketone, 23% of neopentylbutylcarbinyl tert-butylacetate and some tetradecenes. AmMgBr gives I, II, 29% of Am neopentyl ketone, 21% of neopentylamylcarbinyl tert-butylacetate. In no experiment was neopentyl carbinol or its tert-butylacetate found. The above yields are nearly the same as those obtained by adding the acid chloride to an excess of the Grignard reagent. Neopentyl chloride (0.8 mol.), through the Mg derivative, gives with HCHO 0.47 mol. of neopentylcarbinol, b₇₃₉ 140-6°; this with tert-BuCH₂COCl gives 57% of neopentylcarbinyl tert-butylacetate, b₂₆ 104°. tert-BuCH₂CO₂H and EtOH with concentrated H₂SO₄ gives 77% of Et tert-butylacetate, b₇₄₀ 102°.

Journal of the American Chemical Society published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C10H10O3, Computed Properties of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lee, Koo published the artcileReaction of diethyl phosphorochloridite with enolates: a general method for synthesis of β-keto phosphonates and α-phosphono esters through carbon-phosphorus bond formation, Application In Synthesis of 5340-78-3, the publication is Journal of Organic Chemistry (1991), 56(19), 5556-60, database is CAplus.

The reaction of ketone enolates, e.g., from cyclopentanone and LDA, with di-Et phosphorochloridite, followed by air oxidation of the immediate reaction products, has proven to be a general and convenient method for preparation of β-keto phosphonates, e.g., I. Fourteen β-keto phosphonates were prepared by this method, in an average yield greater than 60%. This procedure also appears to be applicable to the preparation of both α-phosphono aldehydes and α-phosphono esters. Although special precautions may be necessary to avoid aldol condensation during formation of aldehydes enolates, in two cases the resulting enolates reacted readily with di-Et chlorophosphite. Finally, a set of five Et esters was converted to α-phosphono esters by this method. Yields of the α-phosphono esters are influenced by steric hindrance at the enolate carbon, but the average yield for this series was ca. 70%. Because this synthetic method relies upon an electrophilic phosphorus reagent for formation of the C-P bond, it is complementary to the traditional Arbuzov synthesis.

Journal of Organic Chemistry published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Application In Synthesis of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ting, Stephen I. published the artcileOxidative Addition of Aryl Halides to a Ni(I)-Bipyridine Complex, SDS of cas: 624-49-7, the publication is Journal of the American Chemical Society (2022), 144(12), 5575-5582, database is CAplus and MEDLINE.

The oxidative addition of aryl halides to bipyridine- or phenanthroline-ligated Ni(I) is a commonly proposed step in Ni catalysis. However, there is a scarcity of complexes of this type that both are well-defined and undergo oxidative addition with aryl halides, hampering organometallic studies of this process. The authors report the synthesis of a well-defined Ni(I) complex, [(^CO2Etbpy)Ni^ICl]₄ (1). Its solution-phase speciation was characterized by a significant population of monomer and a redox equilibrium that can be perturbed by π-acceptors and σ-donors. 1 reacts readily with aryl bromides, and mechanistic studies are consistent with a pathway proceeding through an initial Ni(I) → Ni(III) oxidative addition to form a Ni(III) aryl species. Such a process was demonstrated stoichiometrically for the 1st time, affording a structurally characterized Ni(III) aryl complex.

Journal of the American Chemical Society published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C10H9IO4, SDS of cas: 624-49-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Holman, Samuel D. L. published the artcileElectrochemical Synthesis of Isoxazolines: Method and Mechanism, Quality Control of 624-49-7, the publication is Chemistry – A European Journal (2022), 28(13), e202103728, database is CAplus and MEDLINE.

An electrochem. method for the green and practical synthesis of a broad range of substituted isoxazoline cores is presented. Both aryl and more challenging alkyl aldoximes are converted to the desired isoxazoline in an electrochem. enabled regio- and diastereoselective reaction with electron-deficient alkenes. Addnl., in-situ reaction monitoring methods compatible with electrochem. equipment have been developed in order to probe the reaction pathway. Supporting analyses from kinetic (time-course) modeling and d. functional theory support a stepwise, radical-mediated mechanism, and discounts hypothesised involvement of closed shell [3+2] cycloaddition pathways.

Chemistry – A European Journal published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Quality Control of 624-49-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Maczka, Wanda published the artcileBiotransformation of α-acetylbutyrolactone in Rhodotorula strains, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is International Journal of Molecular Sciences (2018), 19(7), 2106/1-2106/11, database is CAplus and MEDLINE.

Due to its structural similarity, the α-1-hydroxyethyl-γ-butyrolactone obtained by reduction of (±)-α-acetyl-γ-butyrolactone may have a similar function in the body to γ-butyrolactone (GBL). In the work presented, biotransformation of α-acetyl-γ-butyrolactone by three Rhodotorula strains was performed obtaining enantiomerically enriched alc. The process was carried out in growing and resting cultures. We studied how both media composition and organic solvent volume affected stereoselectivity and effectiveness of biotransformation. After 2 h, the enantiomerically pure (3R, 1 S)-α-1-hydroxyethyl-γ-butyrolactone was obtained using the R. marina AM77 strain in YPG (Yeast extract-Peptone-Glucose) medium enriched with 5% glycerol. To our best knowledge there is no previous information in the literature about the (±)-α-acetyl-γ-butyrolactone biotransformation performed in medium with addition of organic and deep eutectic solvents.

International Journal of Molecular Sciences published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xie, Peizhong published the artcileCalcium-catalyzed regioselective dehydrative cross-coupling of propargylic alcohols with 1,3-dicarbonyl compounds, Synthetic Route of 517-23-7, the publication is Green Chemistry (2019), 21(19), 5207-5211, database is CAplus.

A novel calcium-catalyzed in situ dehydrative cross-coupling reaction of propargylic alcs. with 1,3-dicarbonyl compounds was developed. This catalytic system can suppress the competitive Meyer-Schuster rearrangement, control regioselectivity, and enable the desired process to occur under solvent-free conditions at room temperature with water as the only byproduct. A variety of vicinal tertiary and all-carbon quaternary centers can be obtained in high yields with broad functional group tolerance.

Green Chemistry published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C11H8O3, Synthetic Route of 517-23-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics