Cas: 106-02-5 | Xue, Ruipublished an article in 2022

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.HPLC of Formula: 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Xue, Rui;Cui, Er-Liang;Hu, Guo-Quan;Zhu, Ming-Qiang published 《The composition, physicochemical properties, antimicrobial and antioxidant activity of wood vinegar prepared by pyrolysis of Eucommia ulmoides Oliver branches under different refining methods and storage conditions》. The research results were published in《Industrial Crops and Products》 in 2022.HPLC of Formula: 106-02-5 The article conveys some information:

To enhance the quality of wood vinegar (WV), the WV prepared by pyrolyzing Eucommia ulmoides Oliver (EUO) branches at the temperature of 650°C were refined by using different physicochem. methods. The crude WV was refined by ultra-low freezing and thawing (WVFT), charcoal adsorption (WVCA), and activated carbon adsorption (WVACA), resp. Meanwhile, the chem. compositions, antimicrobial and antioxidant activity of the crude WV (WVC), the WV (WVS) prepared two years ago, and the photolysis WV (WVP) were investigated. The results showed that the WVFT obtained by ultra-low freezing and thawing method possessed better quality with pH of 3.45, d. of 1.045 g/cm3 , refractive index of 26.85% and total organic acid of 11.00%. It was also found that WVFT had better inhibition rate of 83.33% against Bacterium prodigiosum, indication the excellent antibacterial activity. Moreover, WVFT had significant effect on scavenging rate (98.72%) for hydroxyl radicals. This research could offer some references for the refining methods of WV, and the WV was expected to be a potential candidate for materials of antioxidant and antimicrobial. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.HPLC of Formula: 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Learn more about cas: 106-02-5 | Journal of Materials Chemistry B: Materials for Biology and Medicine 2019

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Product Details of 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Product Details of 106-02-5In 2019, Gong, Yi-hong;Shu, Man;Xie, Jian-hua;Zhang, Chao;Cao, Zhong;Jiang, Zhao-zhong;Liu, Jie published 《Enzymatic synthesis of PEG-poly(amine-co-thioether esters) as highly efficient pH and ROS dual-responsive nanocarriers for anticancer drug delivery》. 《Journal of Materials Chemistry B: Materials for Biology and Medicine》published the findings. The article contains the following contents:

Novel multifunctional drug nanocarriers have been successfully fabricated from a new type of enzymically synthesized, biodegradable block copolymer, PEG-poly(ω-pentadecalactone-co-N-methyldiethyleneamine-co-3,3′-thiodipropionate) (PEG-PPMT), which was responsive to tumor-relevant acidic pH (5.0-6.5) and intracellular reactive oxygen species (ROS) of tumor cells. The PEG-PPMT copolymers could self-assemble to form nano-scaled particles in aqueous solutions, which are stable in physiol. solutions, but swell substantially upon reducing the pH from 7.4 to 5.0 and/or in the presence of ROS on account of the protonation of the tertiary amino groups and oxidation of the thioether groups, causing a hydrophobic to hydrophilic transition in the nanoparticle cores. Consistently, docetaxel (DTX) encapsulated in PEG-PPMT nanoparticles can be triggered in a synergistic manner by acidic pH and a high-ROS environment in tumor cells to release the hydrophobic drug at accelerated rates for efficient tumor growth inhibition. In particular, DTX encapsulated in PEG-PPMT-11% PDL and PEG-PPMT-28% PDL nanoparticles exhibit extraordinarily enhanced potency (95% and 93% tumor-inhibiting efficiency, resp.) in inhibiting the growth of ROS-rich CT-26 tumors xenografted in mice. Importantly, biosafety analyses show minimal toxicity of DTX-loaded PEG-PPMT nanoparticles toward normal organs including liver and kidneys during the in vivo antitumor treatments. These results demonstrate that the PEG-PPMT nanoparticles are promising pH and ROS dual-responsive multifunctional nanocarriers for tumor site specific, controlled release of anticancer drugs to treat ROS-rich tumors.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.Product Details of 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cas: 112-62-9 | Maidana Serpa, John Dayvan et al. made new progress in 2022

Methyl oleate(cas: 112-62-9) is an intermediate for detergents, emulsifiers, wetting agents, stabilizers, textile treatments, plasticizers for duplicating inks, rubbers, waxes etc.Formula: C19H36O2 It is also used in biochemical research as a chromatographic reference standard.

Formula: C19H36O2In 2022, Maidana Serpa, John Dayvan;Cavalieri de Alencar Guimaraes, Nelciele;Kioshi Yonekawa, Murilo Aquino;Pereira de Almeida, Aline;Ruller, Roberto;Augusto dos Santos Jaques, Jeandre;Santos, Edson dos Anjos dos;Masui, Douglas Chodi;Zanoelo, Fabiana Fonseca;Giannesi, Giovana Cristina published 《Sarocladium strictum lipase (LipSs) produced using crude glycerol as sole carbon source: A promising enzyme for biodiesel production》. 《Biocatalysis and Agricultural Biotechnology》published the findings. The article contains the following contents:

The production of biodiesel (fatty acid Me esters), an environmentally safe next-generation biofuel, using a lipase from Sarocladium strictum and glycerol (a biodiesel byproduct) as sole carbon source, was investigated. The fungus S. strictum showed maximum lipase production when grown in crude glycerol (3.13 U/mg protein) with 168 h of growth. Different concentrations of crude glycerol as carbon source were tested and concentrations ranging from 0.5 to 4% were completely consumed (100%) by the S. strictum. The lipase from S. strictum was purified (24.4-fold) with a specific activity of 73.2 U/mg protein showing a mol. weight of 52 kDa. The effects of pH and temperature in the lipase activity were evaluated showing optimal activity at pH 5.0 and 40°C, resp. Lipase hydrolyzed different substrates and exhibited better activity on p-nitrophenyl octanoate (30.68 U/mg protein). The detergents Triton X-100 and Tween 80 at concentration of 0.1% (volume/volume) increased the lipase activity by 10.45 and 8.55%, resp. The lipase maintained 80% residual activity in the presence of methanol (1:1, volume/volume) after 24 h of incubation. In concentrations ranging from 1 to 5% of methanol, showed activity above 90%, maintaining 70% activity at 10% concentration Gas chromatog. mass spectrometry (GC-MS) anal. confirmed biodiesel production with soybean and sunflower oil by lipase with a conversion rate of approx. 65 and 85%, resp. Therefore, the lipase was efficient in the conversion of low-cost plant oil to high-value biodiesel.Methyl oleate (cas: 112-62-9) were involved in the experimental procedure.

Methyl oleate(cas: 112-62-9) is an intermediate for detergents, emulsifiers, wetting agents, stabilizers, textile treatments, plasticizers for duplicating inks, rubbers, waxes etc.Formula: C19H36O2 It is also used in biochemical research as a chromatographic reference standard.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Toxicology In Vitro | Cas: 106-02-5 was involved in experiment

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.COA of Formula: C15H28O2It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Lee, Isabelle;Na, Mihwa;O’Brien, Devin;Parakhia, Rahul;Alepee, Nathalie;Westerink, Walter;Eurlings, Irene;Api, Anne Marie published 《Assessment of the skin sensitization potential of fragrance ingredients using the U-SENS assay》 in 2022. The article was appeared in 《Toxicology In Vitro》. They have made some progress in their research.COA of Formula: C15H28O2 The article mentions the following:

The U-SENS assay was developed to address the third key event of the skin sensitization adverse outcome pathway (AOP) and is described in OECD test guideline 442E, Annex II. A dataset of 68 fragrance ingredients comprised of 7 non-sensitizers and 61 sensitizers was tested in the U-SENS assay. The potential for fragrance ingredients to activate dendritic cells, measured by U-SENS, was compared to the sensitization potential determined by weight of evidence (WoE) from historical data. Of the non-sensitizers, 4 induced CD86 cell surface marker ≥1.5-fold while 3 did not. Of the sensitizers, 50 were predicted to be pos. in U-SENS, while the remaining 11 were neg. Pos. and neg. predictive values (PPV and NPV) of U-SENS were 93% and 21%, resp. No specific chem. property evaluated could account for misclassified ingredients. Assessment of parent and metabolite protein binding alerts in silico suggests that parent chem. metabolism may play a role in CD86 activation in U-SENS. Combining the U-SENS assay in a “2 out of 3” defined approach with the direct peptide reactivity assay (DPRA) and KeratinoSens predicted sensitization hazard with PPV and NPV of 97% and 24%, resp. Combining complementary in silico and in vitro methods to the U-SENS assay should be integrated to define the hazard classification of fragrance ingredients, since a single NAM cannot replace animal-based methods. The experimental procedure involved many compounds, such as Oxacyclohexadecan-2-one (cas: 106-02-5) .

Oxacyclohexadecan-2-one(cas:106-02-5) is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.COA of Formula: C15H28O2It may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of cas: 124-06-1 | Xu, Baoguo et al. published an article in 2022

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.Synthetic Route of C16H32O2Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Synthetic Route of C16H32O2《Selection of drying techniques for Pingyin rose on the basis of physicochemical properties and volatile compounds retention》 was published in 2022. The authors were Xu, Baoguo;Feng, Min;Chitrakar, Bimal;Wei, Benxi;Wang, Bo;Zhou, Cunshan;Ma, Haile;Wang, Bin;Chang, Lu;Ren, Guangyue;Duan, Xu, and the article was included in《Food Chemistry》. The author mentioned the following in the article:

Awareness of edible rose being beneficial for health has attracted researchers in exploring different rose products. The study aimed to investigate effects of vacuum freeze drying (VFD), hot air drying (HAD), heat pump drying (HPD), relative humidity drying (RHD) and catalytic IR drying (CID) on the physicochem. properties, and volatile organic compounds (VOCs) of Pingyin roses. Results showed that the VFD roses had significantly (p < 0.05) bright color, complete tissue cells, low shrinkage, and good plasma membrane permeability. CID roses showed the highest total phenols content (164.09 ± 0.88 mg/g) and the strongest antioxidant activity. Besides, the odor is the most crucial indicator for dried roses. VFD can well prevent the odor from diminishing/destroying and preserve the natural smell of rose. Thermal drying including HAD, HPD, RHD, and CID, could cause significant losses of VOCs. Consequently, the findings can provide the scientific basis for future large-scale production of dried rose products. And Ethyl tetradecanoate (cas: 124-06-1) was used in the research process.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.Synthetic Route of C16H32O2Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cas: 112-62-9 was involved in experiment | International Journal of Food Science and Technology 2022

Methyl oleate(cas: 112-62-9) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of oleic acid with methanol.Related Products of 112-62-9 Methyl oleate(cas: 112-62-9) is an intermediate for detergents, emulsifiers, wetting agents, stabilizers, textile treatments, plasticizers for duplicating inks, rubbers, waxes etc.

Tong, Huiquan;Cao, Changwei;Du, Yanli;Liu, Yong;Huang, Wei published 《Ultrasonic-assisted phosphate curing: a novel approach to improve curing rate and chicken meat quality》 in 2022. The article was appeared in 《International Journal of Food Science and Technology》. They have made some progress in their research.Related Products of 112-62-9 The article mentions the following:

The effects of ultrasound-assisted phosphate curing (UPC), phosphate curing (PC), and deionised water curing (DC) on the quality of chicken breast meat were investigated. The anal. of tissue sections, low-field NMR (LF-NMR), and headspace solid-phase microextraction gas-phase mass spectrometry (HS-SPME-GC-MS) of water distribution, myofibrillary structure, and volatile components of the meat samples were performed to reveal the mechanism. Also, the curing rate, water holding capacity (WHC), and shear force of meat were assessed. The results revealed that ultrasonic-assisted salting improved the meat salting rate, WHC, and tenderness by mech. destroying the muscle fiber structure, increasing the space between the muscle fiber bundles, promoting water migration and uniform distribution, and reducing water freedom in the treated samples. In addition, HS-SPME-GC-MS anal. revealed that PC significantly reduced the content of volatile flavor components in the chicken breast meat compared with DC (P < 0.05); however, the combination treatment with PC and ultrasonic curing could reconstruct the flavor loss caused by phosphate. Thus, our cumulative results suggest that the ultrasonic technol. may effectively assist the processing technol. in improving the quality of meat and reconstructing the flavor loss in meat products. To complete the study, the researchers used Methyl oleate (cas: 112-62-9) .

Methyl oleate(cas: 112-62-9) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of oleic acid with methanol.Related Products of 112-62-9 Methyl oleate(cas: 112-62-9) is an intermediate for detergents, emulsifiers, wetting agents, stabilizers, textile treatments, plasticizers for duplicating inks, rubbers, waxes etc.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yao, Di et al. published new progress in experiments with the help of cas: 124-06-1

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.HPLC of Formula: 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Yao, Di;Ma, Lixue;Wu, Mengna;Wang, Xiaoyu;Xu, Lei;Yu, Qiaoru;Wang, Changyuan published 《Effect of microbial communities on the quality characteristics of northeast soybean paste: Correlation between microorganisms and metabolites》 in 2022. The article was appeared in 《LWT–Food Science and Technology》. They have made some progress in their research.HPLC of Formula: 124-06-1 The article mentions the following:

To systematically explore the impact of microbial community composition on the quality characteristics of northeast soybean paste, the microbial community structure was determined by high-throughput sequencing technol. and the flavor substance, free amino acid (FAA) and biogenic amine (BA) contents were determined by HS-SPME-GC-MS and HPLC. Furthermore, the correlation between microorganisms and metabolites was investigated. The results indicated that the core bacteria mainly included Tetragenococcus, Bacillus and Lactobacillus; Candida_f__norank, Wickerhamomyces and Aspergillus were the dominant fungi. A total of 139 flavor compounds were detected in all samples, and decamethylcyclopentasiloxane, isoamyl phenylacetate and octamethylcyclotetrasiloxane accounted for the highest proportion. A total of 24 FAAs were detected in the soybean paste. Pantoea, Kroppenstedtia and Kocuria were significantly pos. correlated with most FAAs (p < 0.05). Addnl. 5 BAs were detected in the soybean paste, and the contents of BAs in Y4 were highest, which was affected by different microbes. This study provided relevant information for the microbial community composition and metabolites of northeast soybean paste, which was of great significance for understanding the characteristics and safety of soybean paste.Ethyl tetradecanoate (cas: 124-06-1) were involved in the experimental procedure.

Ethyl tetradecanoate(cas: 124-06-1) is a natural product found in Psidium guajava, Litchi chinensis, and other organisms.HPLC of Formula: 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of cas: 106-02-5 | Iwasaki, Tomoya et al. published an article in 2019

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.HPLC of Formula: 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

HPLC of Formula: 106-02-5《Synthesis of 23-, 25-, 27-, and 29-Membered (Z)-Selective Unsaturated and Saturated Macrocyclic Lactones from 16- and 17-Membered Macrocyclic Lactones and Bromoalcohols by Wittig Reaction, Yamaguchi Macrolactonization, and Photoinduced Decarboxylative Radical Macrolactonization》 was published in 2019. The authors were Iwasaki, Tomoya;Tajimi, Yuka;Kameda, Kenta;Kingwell, Callum;Wcislo, William;Osaka, Kazuyuki;Yamawaki, Mugen;Morita, Toshio;Yoshimi, Yasuharu, and the article was included in《Journal of Organic Chemistry》. The author mentioned the following in the article:

A new strategy for the synthesis of 23-, 25-, 27-, and 29-membered (Z)-selective unsaturated and saturated macrocyclic lactones from com. available 16- and 17-membered macrocyclic lactones and bromoalcs. by Wittig reaction, Yamaguchi macrolactonization, and photoinduced decarboxylative radical macrolactonization is described. The position of the unsaturated part in the macrocyclic lactones can be controlled by changing the number of carbons in the starting materials. This protocol can provide facile access to the desired large-ring (Z)-selective unsaturated and saturated macrocyclic lactones from simple starting materials.Oxacyclohexadecan-2-one (cas: 106-02-5) were involved in the experimental procedure.

Oxacyclohexadecan-2-one(cas:106-02-5) is a natural product found in Lonicera japonica and Angelica archangelica.HPLC of Formula: 106-02-5 It is a macrocyclic lactone that can be used as a flavoring agent and fragrance ingredient due to its musk flavor/odor.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of cas: 124-06-1 | Zou, Yuke et al. published an article in 2022

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Safety of Ethyl tetradecanoateEthyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Safety of Ethyl tetradecanoateIn 2022, Zou, Yuke;Zhong, Yixin;Huang, Lihui;Xu, Wei;Wu, Yanping;Gao, Jia;Zhong, Kai;Gao, Hong published 《Effects of brown sugar addition and fermentation time on metabolites and microbial communities of Yibin Yacai》. 《LWT–Food Science and Technology》published the findings. The article contains the following contents:

Yibin Yacai is one of the most popular pickled vegetables in Sichuan made from special local stem mustard via spontaneous fermentation The final quality of the Yibin Yacai product depends on every manufacturing process that affects the microbial communities during fermentation In this study, the effects of brown sugar addition and fermentation time on physicochem. quality, flavor, and microbial communities of Yibin Yacai under five different fermentation conditions were investigated. The brown sugar addition can effectively increase the activities of microorganisms such as Lactobacillus and Debaryomyces, resulting in an increase in lactic acid content, sweet amino acids and umami amino acids. Furthermore, fermentation time plays a critical role in determining their physicochem. quality and flavor. The Yibin Yacai samples fermented for 5 years present the highest content of reducing sugar, amino acid nitrogen, esters, aldehydes, and olefins, while having the lowest salinity. These results indicate that the brown sugar addition and fermentation time could significantly influence the physicochem. and flavor qualities of the Yibin Yacai by tuning microbial communities during fermentation These findings reveal the importance of controlling manufacturing processes for traditionally fermented Yibin Yacai and provide a new perspective on the technol. innovation of fermented Yibin Yacai. And Ethyl tetradecanoate (cas: 124-06-1) was used in the research process.

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Safety of Ethyl tetradecanoateEthyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of cas: 124-06-1 | Yang, Yijin et al. published an article in 2022

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Application of 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Application of 124-06-1《Flavor compounds with high odor activity values (OAV > 1) dominate the aroma of aged Chinese rice wine (Huangjiu) by molecular association》 was published in 2022. The authors were Yang, Yijin;Ai, Lianzhong;Mu, Zhiyong;Liu, Haodong;Yan, Xin;Ni, Li;Zhang, Hui;Xia, Yongjun, and the article was included in《Food Chemistry》. The author mentioned the following in the article:

Aging is an essential operation to perfect the flavor quality of Hungjiu. In this study, formation mechanism of flavor compounds responsible for the characteristic flavor of aged Huangjiu was investigated. The contents of umami and bitter free amino acids (FAA) increased with the storage period prolonged, while that of sweet FAA showed downward trend. Gas chromatograph-mass spectrometry and principal component anal. indicated that the volatile flavor compounds with OAV exceed 1, especially middle-chain fatty-acid-ethyl-esters and aromatic compounds, dominated the characteristic flavor of aged Huangjiu. Low field-NMR was firstly applied to characterize the mol. association between water and dissolved flavor compounds in aged Huangjiu. The results showed that basic amino acids contributed greatly to the flavor formation of aged Huangjiu via mol. association In addition, the mol. association significantly promoted the accumulation of flavor compounds with OAV > 1, especially Et esters.Ethyl tetradecanoate (cas: 124-06-1) were involved in the experimental procedure.

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Application of 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics