Tag: 200-300

Wang, Lan; Zhang, Yuhuan; Han, Ying; Zhang, Qi; Wen, Zhenfu; Li, Hongjuan; Sun, Shiguo; Chen, Xin; Xu, Yongqian published an article in 2021. The article was titled 《Nanoscale photosensitizer with tumor-selective turn-on fluorescence and activatable photodynamic therapy treatment for COX-2 overexpressed cancer cells》, and you may find the article in Journal of Materials Chemistry B: Materials for Biology and Medicine.SDS of cas: 51857-17-1 The information in the text is summarized as follows:

Effective targeting and in situ imaging-guided treatment are particularly important for accurate clin. photodynamic therapy (PDT) of malignant tumors. Herein, we propose a single mol., named IMC-DAH-SQ, which possesses dual-targeting components, including structure-inherent targeting (SIT) and cyclooxygenase-2 (COX-2) targeting units, and controllable turn-on near IR (NIR) fluorescence. Due to its amphiphilicity, IMC-DAH-SQ assembles into a nanoprobe with low background fluorescence. After incubation with tumor cells, the SIT and COX-2 recognition characteristics of IMC-DAH-SQ endow it with preferential tumor-targeting activity. The strong binding with overexpressed COX-2 can collapse the nanoprobe to monomers after accumulation in tumor cells, leading to turn-on NIR fluorescence that is completely different from normal cells. Addnl., benefiting from the single mol. model tactic, the nanoprobe has the advantages of simple synthesis without ever considering the loading rate and separation between the photosensitizer and targeting unit. Other favorite features, including superior biocompatibility, weak dark toxicity, and mitochondria enrichment capability, are implemented. All these traits not only afford nanoprobe precision tumor cell targeting capability but also provide promising imaging-guided antitumor therapy. We believe that the single mol. protocol will establish a novel strategy for simultaneous diagnosis and anticancer medicine treatment utilizing versatile but small compounds In the experimental materials used by the author, we found N-Boc-1,6-Diaminohexane(cas: 51857-17-1SDS of cas: 51857-17-1)

N-Boc-1,6-Diaminohexane(cas: 51857-17-1) is a compound useful in organic synthesis used in the preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groupsSDS of cas: 51857-17-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Metal carbonyl chemistry. XXI. Comparison of the reactivities of dicarbonylbis(triphenylphosphine)cobaltate(1-), -iridate(1-), and -rhodate(1-) towards fluoroaromatic compounds》 were Booth, Brian L.; Haszeldine, Robert N.; Perkins, Ian. And the article was published in Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999) in 1975. Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate The author mentioned the following in the article:

Nucleophilic substitution reactions of [M(CO)2(PPh3)2]- (M = Co, Ir) with perfluoroarom. compounds, e.g. pentafluoropyridine (C5F5N), gave aromatic metal complexes, e.g. 4-RC5F4N [R = M(CO)2(PPh3)2]. The relative reactivities of the Co, Ir, and corresponding Rh anions towards C5F5N were established by kinetic studies in the order [Rh(CO)2(PPh3)2]- > [Ir(CO)2(PPh3)2]- > [Co(CO)2(PPh3)2]-.Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate) was used in this study.

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《The toxicity of some fluoroaromatic compounds》 was published in Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologo-Meditsinskikh Nauk in 1967. These research results belong to Lapik, A. S.; Zimina, L. N.. Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate The article mentions the following:

The oral LD50 of the following compounds were determined for white mice: benzaldehyde 1240, pentafluorobenzaldehyde 320, benzoic acid 2800, pentafluorobenzoic acid 2500, acetophenone 970, pentafluoroacetophenone 850, decafluorohydrobenzoin 485, dinitrodecafluorohydrobenzoin 5000, terephthalic acid 585, tetrafluoroterephthalic acid 350, di-Me tetrafluoroterephthalate 870, phthalic acid 560, tetrafluorophthalic acid (I) 320, di-Me I 780, pentafluorobromobenzene 959, ω-bromoacetophenone 690, ω-bromopentafluoroacetophenone 350, Et pentafluorobenzoate 1700, benzophenone 1250, decafluorobenzophenone 960, decafluorobenzhydrol 1350, pentafluorobenzhydrol 1750, ester of decafluorobenzhydrol and HNO3 1750, tris(pentafluorophenyl)methane 1625, benzene 400, pentafluorobenzene 710, pentafluorochlorobenzene 1250, octafluoronaphthalene 670, hexafluoro-1,4-naphthoquinone 450, pentafluoropyridine 280, fluoranil 420 mg./kg. The toxic symptoms were generally similar: decreased motor activity, loss of coordination, paralysis, and death. The benzene derives. had a narcotic effect and octafluoronaphthalene and pentafluoropyridine caused convulsions. The experimental process involved the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Safety of Ethyl 2,3,4,5,6-pentafluorobenzoate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Aromatic nucleophilic substitution. XIV. Kinetics of reactions of methyl and ethyl esters of pentafluorobenzoic acid with sodium alkoxides》 was written by Kobrina, L. S.; Furin, G. G.; Kollegov, V. F.; Chertok, V. S.; Yakobson, G. G.. COA of Formula: C9H5F5O2 And the article was included in Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Khimicheskikh Nauk in 1972. The article conveys some information:

Nucleophilic substitution of C6F5CO2R (R = Me, Et) by the corresponding NaOR in ROH-Et2O, MeOH-dioxane, and MeOH-C6H6 was 1st order in each reagent. The rate of ortho substitution decreased more sharply with increasing alc. content of the solvent than that of the para substitution; however, the rate of para substitution in MeOH-C6H6 increased with the solvent polarity. In the experimental materials used by the author, we found Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4COA of Formula: C9H5F5O2)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. COA of Formula: C9H5F5O2 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Fluorine-19 nuclear magnetic resonance studies on some polyfluoro aromatic compounds and their metal complexes》 were Bruce, M. I.. And the article was published in Journal of the Chemical Society [Section] A: Inorganic, Physical, Theoretical in 1968. COA of Formula: C9H5F5O2 The author mentioned the following in the article:

The high-resolution 19F N.M.R. spectra of several polyfluoro aromatic compounds and of derived transition-metal complexes are presented and discussed. Substituent shielding parameters are tabulated for many commonly encountered functional groups, and details of the identification of complex products from the reaction of the anion [(π-C5H5)Fe-(CO)2]- with C6F5CN, 1,2-C6F4I2 and C6F5Br are given. The nature of the complexes formed has been confirmed by use of high-resolution mass-spectrometric techniques in the latter two cases. 17 references. The results came from multiple reactions, including the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4COA of Formula: C9H5F5O2)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. COA of Formula: C9H5F5O2 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《The first tryptophan based turn-off chemosensor for Fe2+ ion detection》 was written by Nagarajan, Rajendran; Vanjare, Balasaheb D.; Hwan Lee, Ki. COA of Formula: C12H15ClN2O2This research focused ontryptophan fluorescent chemosensor iron ion detection; Chemosensor; Fe(2+) ion sensor; Fluorescence quenching; Metal ions; PET mechanism; Tryptophan. The article conveys some information:

In this research work, we have designed and synthesized a novel Tryptophan-Quinoline conjugated turn-off chemosensor 4 (I) for the selective detection of Fe2+ ion with high sensitivity (3.06μM) among 21 metal cations such as Ag+, Ca+, Cs+, Cu+, K+, Na+, NH+4, Ba2+, Ca2+, Cd2+, Co2+, Cu2+, Mn2+, Ni2+, Pb2+, Zn2+, Al3+, Au3+, Cr3+ and Fe3+ in DMF-HEPES (1 mM, pH = 7.0, 1:1, volume/volume) aqueous-organic solvent system. It showed a fluorescence quenching mechanism through the blocked PET process. The optical properties, binding mode of the metal ion with the receptor, plausible electron transfer mechanism, and its practical applications have been discussed. This work will open up a new avenue in amino acid-based Fe2+ ion sensors. The results came from multiple reactions, including the reaction of H-Trp-OMe.HCl(cas: 7524-52-9COA of Formula: C12H15ClN2O2)

H-Trp-OMe.HCl(cas:7524-52-9) is one of amino acid derivatives. Amino acid derivatives represent an important category of skin penetration promoters. These compounds possess hydrophobic chains attached to an amino acid headgroup via a biodegradable ester bond. Due to the amphiphilic nature of these derivatives, it is possible for them to enter into the SC lipid barrier and significantly disorganize skin membrane lipids.COA of Formula: C12H15ClN2O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Electronic structure and photoelectron spectra of fluoroorganic derivatives of benzoic acids》 was written by Petrachenko, N. E.. SDS of cas: 4522-93-4 And the article was included in Poverkhnost: Rentgenovskie, Sinkhrotronnye i Neitronnye Issledovaniya on August 31 ,1997. The article conveys some information:

The electronic structure of fluorinated benzamides, N-hydroxybenzamides, benzoic acid esters, benzophenones was studied by photoelectron spectroscopy and MNDO calculations in order to elucidate the role of the HOMOs in formation of chem. bonds between the substituent and the fluorinated ring.Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4SDS of cas: 4522-93-4) was used in this study.

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.SDS of cas: 4522-93-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sanchez, Ramon;Rodriguez-Nogales, Jose Manuel;Fernandez-Fernandez, Encarnacion;Gonzalez, Maria Rosa;Medina-Trujillo, Laura;Martin, Pedro published 《Volatile composition and sensory properties of wines from vineyards affected by iron chlorosis》. The research results were published in《Food Chemistry》 in 2022.SDS of cas: 124-06-1 The article conveys some information:

Recent studies have shown that mild to moderate iron chlorosis can have pos. effects on grape quality potential, including volatile profile. The main objective of this work was to investigate, for the first time, how moderate iron stress in grapevines affects the presence of volatile organic compounds (VOCs) in wines. The study was carried out during 2018-2019 seasons, in 20 Tempranillo vineyard subzones with different degree of iron deficiency, located in Ribera del Duero (North-Central Spain). The results showed that moderate iron stress increased in wines the concentrations of VOCs associated with floral notes, such as 2-phenylacetaldehyde, 2-phenylethanol and 2-phenylethyl acetate, while reducing the presence of C6-alcs., responsible for green-herbaceous aroma. A favorable reduction of pH and a betterment of parameters related to color were detected in wines from iron deficient subzones. Chlorosis incidence was associated to improvements in wine sensory attributes as layer intensity, black fruit and aroma intensity. To complete the study, the researchers used Ethyl tetradecanoate (cas: 124-06-1) .

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.SDS of cas: 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Product Details of 124-06-1In 2021, Yang, Linzi;Li, Xueli;Lu, Yunhao;Lv, Yuanping;Chi, Yuanlong;He, Qiang published 《Ester synthesis mechanism and activity by Bacillus licheniformis, Candida etchellsii, and Zygosaccharomyces rouxii isolated from Chinese horse bean chili paste》. 《Journal of the Science of Food and Agriculture》published the findings. The article contains the following contents:

Esters are indispensable aroma compounds and contribute significantly to the fruity aromas in fermented condiments. The ester synthesis activity and pathways of Bacillus licheniformis, Candida etchellsii, and Zygosaccharomyces rouxii, isolated from Chinese horse bean chili-paste (CHCP), were investigated. Chem. buffer models containing esterification and alcoholysis systems inoculated with extracellular extracts of these three strains were established. The ester synthesis activity of C. etchellsii was stronger than that of the other two strains. Zygosaccharomyces rouxii could synthesize acetate esters via esterification, whereas the biosynthesis pathways of B. licheniformis and C. etchellsii were esterification and alcoholysis. Esterification exhibited relatively high activity at pH 4, whereas alcoholysis activity improved with an increase in the pH from 4 to 8. Candida etchellsii could synthesize C₆-C₈ of acetate esters, and its activity improved with the number of alc. carbon atoms. These three strains could synthesize C₁₀-C₁₈ of Et esters. Their Et ester synthesis activity decreased with the aliphatic acid carbon number Candida etchellsii has the potential to be used in CHCP fermentation to accumulate esters and improve flavor compared with the other two strains. This research is helpful in explaining the mechanism of ester synthesis in fermented condiments. 2021 Society of Chem. Industry. To complete the study, the researchers used Ethyl tetradecanoate (cas: 124-06-1) .

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Product Details of 124-06-1Ethyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Xuzeng;Wang, Zhaogai;Feng, Tao published 《Screening of Yeast in Various Vineyard Soil and Study on Its Flavor Compounds from Brewing Grape Wine》. The research results were published in《Molecules》 in 2022.Name: Ethyl tetradecanoate The article conveys some information:

In order to screen out Saccharomyces cerevisiae suitable for table grape fermentation, and compare it with com. Saccharomyces cerevisiae in terms of fermentation performance and aroma producing substances, differences of fermentation flavor caused by different strains were discussed. In this experiment, yeast was isolated and purified from vineyard soil, 26s rDNA identification and fermentation substrate tolerance anal. were carried out, and the causes of flavor differences of wine were analyzed from three aspects: GC-MS, PCA and sensory evaluation. The results showed that strain S1 had the highest floral aroma fraction, corresponding to its high production of Et octanoate and other substances, and it had the characteristics of high sugar tolerance. The fruit sensory score of S3 wine was the highest among the six wines. Through exploration and anal., it was found that compared with com. Saccharomyces cerevisiae, the screened strains had more advantages in fermenting table grapes. The flavor of each wine was directly related to the growth characteristics and tolerance of its strains.Ethyl tetradecanoate (cas: 124-06-1) were involved in the experimental procedure.

Ethyl tetradecanoate(cas: 124-06-1) is a labeled component from essential oil of natural hawthorn perfume. Also frequently used in cosmetics, soaps, and flavorings.Name: Ethyl tetradecanoateEthyl myristate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of myristic acid with the hydroxy group of ethanol.

Reference:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics