Tag: 200-300

Retro-inverso tripeptide renin inhibitors was written by Patel, Dinesh V.;Ryono, Denis E.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1992.Synthetic Route of C11H20O4 This article mentions the following:

Retro-inverso tripeptide renin inhibitors I and II were prepared as backbone modifications of tripeptide alc. renin inhibitor Boc-Phe-His-Leu-ol (III) (I₅₀ = 16 μM). While the diastereomeric mixture of partial retro analog II was substantially less active (I₅₀ = 1,200 μM), the complete retro-inverso modification was well tolerated as evidenced by the equipotency of a diastereomer of I (I₅₀ = 20 μM) to parent compound III. In the experiment, the researchers used many compounds, for example, Diethyl isobutylmalonate (cas: 10203-58-4Synthetic Route of C11H20O4).

Diethyl isobutylmalonate (cas: 10203-58-4) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Synthetic Route of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Introducing Catalytic Lossen Rearrangements: Sustainable Access to Carbamates and Amines was written by Kreye, Oliver;Wald, Sarah;Meier, Michael A. R.. And the article was included in Advanced Synthesis & Catalysis in 2013.Synthetic Route of C12H22O4 This article mentions the following:

A new, highly efficient and environmentally benign catalytic variant of the Lossen rearrangement is described. Di-Me carbonate (DMC) as green activation reagent of hydroxamic acids in presence of catalytic amounts of tertiary amine bases {1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), 1,8-diazabicyclo 5.4.0 undec-7-ene (DBU), 1,4-diazabicyclo[2.2.2]octane (DABCO), and triethylamine} and small quantities of methanol initiate the rearrangement. Me carbamates were obtained in good to moderate yields when aliphatic hydroxamic acids were employed in this catalytic Lossen rearrangement; under the same conditions aromatic hydroxamic acids yielded anilines. Notably, the mixture of DMC/methanol was recycled several times without observing decreased yields, thus minimizing the produced waste. Moreover, several other organic carbonates were successfully employed in the catalytic Lossen rearrangement procedure. In the experiment, the researchers used many compounds, for example, Dimethyl decanedioate (cas: 106-79-6Synthetic Route of C12H22O4).

Dimethyl decanedioate (cas: 106-79-6) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C12H22O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preservation of the Conformational Structures of Single-Polymer Crystals in Solution was written by Itoh, Takahito;Suzuki, Tatsuya;Kondo, Fumiaki;Suzuki, Takumi;Uno, Takahiro;Kubo, Masataka;Tohnai, Norimitsu;Sanda, Fumio;Miyata, Mikiji. And the article was included in Macromolecules (Washington, DC, United States) in 2022.Computed Properties of C11H20O4 This article mentions the following:

We have found that the cis-conformational structures in single-polymer crystals obtained by solid-state polymerization are retained in solution A soluble alternating copolymer was accidentally obtained during our research employing a series of 7,7,8,8-tetrakis(alkoxycarbonyl)-p-quinodimethanes (1) with alkoxy groups such as methoxy(1a(Me)), ethoxy(1b(Et)), propoxy(1c(Pr)), isopropoxy(1d(iPr)), butoxy(1e(Bu)), isobutoxy(1f(iBu)), pentyloxy(1g(Pen)), hexyloxy(1h(Hex)), and dodecyloxy(1i(Dod)). Thus, 1a(Me), 1b(Et), 1c(Pr), 1e(Bu), and 1g(Pen) with linear alkoxy groups afforded 1:1 charge-transfer complex crystals with 7,7,8,8-tetracyanoquinodimethane (3), while 1d(iPr), 1f(iBu), 1h(Hex), and 1i(Dod) with branching or linear long-chain alkoxy groups did not. The former crystals topochem. underwent photochem. and thermal copolymerizations via a radical mechanism to yield cis-conformational alternating copolymer crystals according to X-ray crystallog. Attractively, the rates of thermal copolymerization were found to increase roughly with an increase in the chain length of the linear alkoxy groups and/or a decrease in the reacting exomethylene carbon distances between 1 and 3. This finding led us to carry out a spontaneous copolymerization of 1g(Pen) with 3 in solution, resulting in the first synthesis of a soluble alternating copolymer during our research. Spectral analyses of the soluble copolymer of 1g(Pen) with 3, together with geometry optimization and spectroscopic simulations, proved that the cis-conformational structure was retained in solution as well as in the solid state. This provides the first spectral observation of a cis-conformational structure in solution with respect to the alternating copolymers of the p-quinodimethane derivatives In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Computed Properties of C11H20O4).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C11H20O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gas chromatographic analysis of different homologous series of acids esterified in aqueous solutions with butyl and propyl alcohols was written by Molnar-Perl, I.;Pinter-Szakacs, M.;Morvai, M.;Fabian-Vonsik, V.. And the article was included in Journal of Chromatography in 1988.Recommanded Product: 1190-39-2 This article mentions the following:

Fatty acids and aliphatic and aromatic di- and polycarboxylic acids were esterified with aliphatic alcs. in the presence of water and a mineral acid as catalyst. The efficiency of derivatization as well as the detector responses obtained with two alcs. are compared with each other to establish the optimum conditions for various series of acids. The molar ratios of water/alc. which yielded quant. esterifications are given, as is the maximum water content of the esterifying mixture permitted in order for esterification to proceed to completion. The optimum conditions for a reasonable ester yield in the presence of anhydrous Na₂SO₄ are also presented. In the experiment, the researchers used many compounds, for example, malonic acid dibutyl ester (cas: 1190-39-2Recommanded Product: 1190-39-2).

malonic acid dibutyl ester (cas: 1190-39-2) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 1190-39-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reactions of vanillin and vanillal esters with 6-quinolylamine and phenidone was written by Gusak, K. N.;Kozlov, N. G.. And the article was included in Russian Journal of General Chemistry in 2005.Name: 4-Formyl-2-methoxyphenyl isobutyrate This article mentions the following:

2-Alkoxy-4-(11-oxo-9-phenyl-7,8,9,10,11,12-hexahydrobenzo[b][4,7]phenanthrolin-12-yl)phenyl esters, e.g., I, were prepared by condensation of vanillin or vanillal alkanoates with 6-quinolylamine and Phenidone. According to the ¹H NMR spectra, the target products were formed as mixtures of diastereomers. In the experiment, the researchers used many compounds, for example, 4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4Name: 4-Formyl-2-methoxyphenyl isobutyrate).

4-Formyl-2-methoxyphenyl isobutyrate (cas: 20665-85-4) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: 4-Formyl-2-methoxyphenyl isobutyrate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Copper-Catalyzed Methyl Esterification Reactions via C-C Bond Cleavage was written by Zhu, Yan;Yan, Hong;Lu, Linhua;Liu, Defu;Rong, Guangwei;Mao, Jincheng. And the article was included in Journal of Organic Chemistry in 2013.Recommanded Product: 2327-45-9 This article mentions the following:

The highly effective synthesis of Me esters from benzylic alcs., aldehydes, or acids via copper-catalyzed C-C cleavage from tert-Bu hydroperoxide is reported in this paper for the first time. Our protocol is easily accessible and practical, making it a possible supplement for the traditional way. In the experiment, the researchers used many compounds, for example, Methyl 5-methoxy-2-nitrobenzoate (cas: 2327-45-9Recommanded Product: 2327-45-9).

Methyl 5-methoxy-2-nitrobenzoate (cas: 2327-45-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 2327-45-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gelation kinetics of RAFT radical copolymerization of methacrylate and dimethacrylate was written by Yu, Qiang;Gan, Qian;Zhang, Hongwen;Zhu, Shiping. And the article was included in ACS Symposium Series in 2009.Name: Benzyl benzodithioate This article mentions the following:

The gelation kinetics and network development in the RAFT copolymerization of oligo(ethylene glycol) Me ether methacrylate (OEGMEMA) and oligo(ethylene glycol) dimethacrylates (OEGDMA) were investigated using differential scanning calorimetry, solvent extraction/swelling technique, and dynamic mech. anal. A significant autoacceleration was observed in the RAFT copolymerization processes. For the RAFT systems with 2.56, 5.26, 8.11, and 11.11 mol% OEGDMA, the vinyl conversions at the onset of autoacceleration were ∼26, 21, 17, and 15%, resp., very close to the corresponding microgel points. This suggested that the highly branched chains and gels restricted the mobilities of propagating radicals and RAFT-capped chains, resulting in the autoacceleration. The gelation behavior in the RAFT process was different from that in conventional free radical polymerization The slow chain growth in the RAFT process allowed sufficient chain relaxation and uniform distribution of reacting species, which reduced intramol. crosslinking and limited microgel formation. Increasing OEGDMA concentration level resulted in earlier gelation and faster network development, giving rise to network products with higher crosslinking densities, higher glass transition temperatures, and deteriorated structural homogeneities. In the experiment, the researchers used many compounds, for example, Benzyl benzodithioate (cas: 27249-90-7Name: Benzyl benzodithioate).

Benzyl benzodithioate (cas: 27249-90-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: Benzyl benzodithioate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Continuous-Flow Synthesis of β-Ketoesters and Successive Reactions in One-Flow using Heterogeneous Catalysis was written by Kandasamy, Mohanraj;Ishitani, Haruro;Kobayashi, Shu. And the article was included in Advanced Synthesis & Catalysis in 2022.Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

A continuous-flow procedure for the synthesis of β-keto esters R¹C(O)CH₂CO₂R² (R¹ = cyclopropyl, cyclohexyl, n-nonyl, Ph, PhCH:CH, etc., R² = Et; R¹ = PhCH₂CH₂, R² = Et, i-Pr, t-Bu, Ph, PhCH₂) has been developed through Roskamp reaction between aldehydes R¹CHO and α-diazo esters N₂:CHCO₂R² in the presence of a Sn-MCM-41 catalyst. The viability of this methodol. was confirmed with a range of aldehydes and diazo esters and provided good to excellent yields. Catalyst activity was tested over three days (84 h) of operation, and the yield of the desired β-keto ester was maintained between 73 to 89%. The prepared β-keto esters were smoothly transformed into coumarin derivatives and 5-pyrazolone through condensation reactions in a sequential flow. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oxidation of monoesters of dicarboxylic acids was written by Blanshtein, I. B.;Moskovich, Yu. L.;Proskuryakov, V. A.. And the article was included in Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation) in 1972.Recommanded Product: 12-Methoxy-12-oxododecanoic acid This article mentions the following:

HO2C(CH2)nCO2Me (n = 7 or 10) were oxidized by O in the presence of KMnO4 and Mn stearate to dicarboxylic acids and their monoesters of lower C content. The product distribution was explained by intramol. chain transfer, coupled with decarboxylation. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Recommanded Product: 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Isophthalamide bearing 1-pyrenylethynyl group as a highly fluorescent hydrogen bond motif for anion receptors was written by Kondo, Shin-ichi;Iioka, Jun. And the article was included in Tetrahedron Letters in 2021.Application of 313648-56-5 This article mentions the following:

Isophthalamide-based receptor 2 bearing 1-pyrenylethynyl group I as a fluorophore was prepared for a ratiometric fluorescence sensor for anions. Receptor I showed small hypsochromic shift by UV-vis titrations and ratiometric fluorescence changes upon the addition of anions, in particular biol. important anions such as AcO^–, H₂PO^–₄, and Cl^– with high association constants The high quantum yield of receptor 2 (Φ_F = 0.88) implies that 5-(1-pyrenyl)isophthaloyl amide spacer is a versatile component for various fluorescence receptors. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Application of 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics