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Al-Matarneh, Cristina M.’s team published research in Journal of the Serbian Chemical Society in 2021 | CAS: 623-47-2

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Product Details of 623-47-2

Product Details of 623-47-2In 2021 ,《Synthesis and properties of new fused pyrrolo-1,10-phenanthroline type derivatives》 appeared in Journal of the Serbian Chemical Society. The author of the article were Al-Matarneh, Cristina M.; Rosca, Irina; Shova, Sergiu; Danac, Ramona. The article conveys some information:

New fused pyrrolo-phenanthroline type derivatives were synthesized, in two steps, from 1,10-phenanthroline and evaluated for antimicrobial activity and fluorescence properties. Synthetic approach involved a 3 + 2 dipolar-cycloaddition of some selected N-substituted 1,10-phenanthrolin-1-ium ylides, (m)ethoxycarbonyl and cyano (1,2-di)substituted acetylenes and alkenes, resp. The structures of compounds were supported by anal. and spectroscopic data. The mol. structures of four selected compounds was determined by monocrystal XRD analyses. All synthesized compounds were then evaluated for their potential antimicrobial activity against Staphylococcus aureus ATCC25923, Escherichia coli ATCC25922 and Candida albicans ATCC10231. Two of the compounds demonstrated significant activity against the above tested strains. In the experimental materials used by the author, we found Ethyl propiolate(cas: 623-47-2Product Details of 623-47-2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fritzemeier, Russell G.’s team published research in Angewandte Chemie, International Edition in 2020 | CAS: 623-47-2

《Organocatalytic trans Phosphinoboration of Internal Alkynes》 was written by Fritzemeier, Russell G.; Nekvinda, Jan; Vogels, Christopher M.; Rosenblum, Carol Ann; Slebodnick, Carla; Westcott, Stephen A.; Santos, Webster L.. Recommanded Product: 623-47-2 And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

We report the first trans phosphinoboration of internal alkynes. With an organophosphine catalyst, alkynoate esters and the phosphinoboronate Ph2P-Bpin are efficiently converted into the corresponding trans-α-phosphino-β-boryl acrylate products in moderate to good yield with high regio- and Z-selectivity. This reaction operates under mild conditions and demonstrates good atom economy, requiring only a modest excess of the phosphinoboronate. X-ray crystallog. experiments allowed structural assignment of the unprecedented and densely functionalized (Z)-α-phosphino-β-boryl acrylate products. After reading the article, we found that the author used Ethyl propiolate(cas: 623-47-2Recommanded Product: 623-47-2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Teng’s team published research in Chemical Engineering Journal (Amsterdam, Netherlands) in 2019 | CAS: 872-36-6

Vinylene carbonate(cas: 872-36-6) belongs to esters. Alkyl carbonates find applications as solvents for lithium ion battery electrolytes and the use of high quality battery grade electrolytes having extremely low water (<10 ppm) and acid (<10 ppm) contents are critical for achieving high electrochemical performance.Quality Control of Vinylene carbonate

Quality Control of Vinylene carbonateIn 2019 ,《One-step preparation of poly(ionic liquid)-based flexible electrolytes by in-situ polymerization for dendrite-free lithium ion batteries》 appeared in Chemical Engineering Journal (Amsterdam, Netherlands). The author of the article were Huang, Teng; Long, Man-Cheng; Wang, Xiu-Li; Wu, Gang; Wang, Yu-Zhong. The article conveys some information:

Solid-state battery (SSB) has a new application prospect in the fields of safe energy storage, but the solid electrolyte usually fails to maintain excellent ionic conductivity, good mech. properties and close interfacial contact with the electrode materials simultaneously. A newly-designed poly(ionic liquid)-based quasi solid electrolyte (PIL-QSE) is prepared via 1-step in-situ cross-linked polymerizing 1-vinyl-3-dodecylimidazolium bis(trifluoromethanesulfonyl) imide (VDIM-TFSI), which is filled in poly(vinylidene fluoride-hexafluoropropylene) (PVdF-HFP) porous membrane prepared via phase inversion. The leakage-free PIL-QSE containing a compact cross-linked network structure exhibits optimal performances with outstanding flexibility, favorable thermal stability and improved electrochem. performances including a high room-temperature ionic conductivity of 0.70 mS cm-1, a superior electrochem. window up to 5.0 V as well as a high Li ion transference of 0.52. Also, the PIL-QSE can suppress dendrite formation leading to a good battery performance. The LiFePO4|PIL-QSE|Li cells can maintain a discharge capacity 140.7 mA-h g-1 at 0.05 C with 99.8% coulomb efficiency after 200 cycles and 125.9 mA-h g-1 at 0.1 C with 98.9% capacity contention after 100 cycles at 25°. Because of the flexibility of PIL-QSE, the pouch-type battery based on PIL-QSE cannot only light the red LED lamp in a normal state, but also in a bended/cut state. Both of the excellent performance and easy fabrication of PIL-QSE make it potentially as one of the most promising electrolyte materials for SSPB. In addition to this study using Vinylene carbonate, there are many other studies that have used Vinylene carbonate(cas: 872-36-6Quality Control of Vinylene carbonate) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Devarahosahalli Veeranna, Kirana’s team published research in Organic & Biomolecular Chemistry in 2021 | CAS: 623-47-2

Devarahosahalli Veeranna, Kirana; Kanti Das, Kanak; Baskaran, Sundarababu published their research in Organic & Biomolecular Chemistry in 2021. The article was titled 《Reversal of polarity by catalytic SET oxidation: synthesis of azabicyclo[m.n.0]alkanes via chemoselective reduction of amidines》.HPLC of Formula: 623-47-2 The article contains the following contents:

A one-pot catalytic method has been developed for the stereoselective synthesis of cyclopropane-fused cyclic amidines using CuBr2/K2S2O8 as an efficient single electron transfer (SET) oxidative system. The generality of this mild method is demonstrated with a wide variety of substrates to furnish pharmaceutically important amidines containing aza-bicyclic and novel aza-tricyclic frameworks in very good yields. A chemoselective reduction of cyclic amidines to 2-/3-azabicyclo[m.n.0]alkanes and octahydroindoles has been developed using a NaBH4/I2 reagent system. The synthetic scope of the chemoselective reduction of the amidine functionality has been exemplified in the stereoselective synthesis of an iminosugar based (±)-epiquinamide analog. In the experiment, the researchers used Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chiu, Po-Hao’s team published research in Journal of the Taiwan Institute of Chemical Engineers in 2021 | CAS: 623-47-2

Chiu, Po-Hao; Yang, Yan-Lin; Tsao, Heng-Kwong; Sheng, Yu-Jane published an article in 2021. The article was titled 《Deep learning for predictions of hydrolysis rates and conditional molecular design of esters》, and you may find the article in Journal of the Taiwan Institute of Chemical Engineers.COA of Formula: C5H6O2 The information in the text is summarized as follows:

The hydrolysis rate of an ester is essential for the choice of materials in sustainable and eco-friendly applications. In this work, the autoencoder (AE) model has been constructed to predict the hydrolysis rate by inputting SMILES and partial charges. Moreover, the conditional autoencoder (CAE) model has been developed to design chem. structures of esters that possess hydrolysis rates close to the desired value. By implementing the SMILES enumeration technique and the attention mechanism, our AE model exhibits significantly better performance than SPARC based on the root mean square error. For six biodegradable esters that have no exptl. rate constants, the predictions of our AE model are in agreement with those based on the activation energies calculated from Dmol3. To design an ester satisfying the desired conditions, our CAE model demonstrates its capability of providing the best candidates of esters and their rate constants based on structural similarity and the least difference of hydrolysis rates. The derived structures are similar to the desired structure and their rate constants are close to the targeted value. The results came from multiple reactions, including the reaction of Ethyl propiolate(cas: 623-47-2COA of Formula: C5H6O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pham, Hieu Quang’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2019 | CAS: 872-36-6

The author of 《Approaching the maximum capacity of nickel-rich LiNi0.8Co0.1Mn0.1O2 cathodes by charging to high-voltage in a non-flammable electrolyte of propylene carbonate and fluorinated linear carbonates》 were Pham, Hieu Quang; Hwang, Eui-Hyung; Kwon, Young-Gil; Song, Seung-Wan. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Quality Control of Vinylene carbonate The author mentioned the following in the article:

We report a promising approach to achieve the maximum capacity (>230 mA h g-1) and high capacity retention (95% during 100 cycles) of a nickel-rich cathode of LiNi0.8Co0.1Mn0.1O2 (NCM811) by charging to 4.5 V in a non-flammable electrolyte of propylene carbonate and fluorinated linear carbonates. Our electrolyte permits the stabilization of the cathode-electrolyte interface and cathode structure at high-voltage, enabling stable and safe operation of the Ni-rich cathode for high-energy d. and high-safety lithium-ion and lithium metal batteries. The experimental part of the paper was very detailed, including the reaction process of Vinylene carbonate(cas: 872-36-6Quality Control of Vinylene carbonate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sacarescu, Liviu’s team published research in Journal of Photochemistry and Photobiology, A: Chemistry in 2022 | CAS: 623-47-2

《Synthesis, structural characterization, photophysical study and investigation as fluorescent sensor towards metal ions of 1,2,3-triazole-azaindene hybrids》 was written by Sacarescu, Liviu; Dascalu, Mihaela; Chibac-Scutaru, Andreea-Laura; Roman, Gheorghe. Product Details of 623-47-2This research focused ontriazole azaindene metal ion detection optical structural property. The article conveys some information:

The effect of conjugation between 1,2,3-triazole ring system and azaindene scaffolds (either indolizine or imidazo[1,2-a]pyridine) on fluorescence has been examd Three novel 1,2,3-triazole-indolizine hybrids have been prepared either through the Chichibabin indolizine formation or using 1,3-dipolar cycloaddition of activated alkynes to a pyridinium N-ylide, while a structurally related 1,2,3-triazole-substituted imidazo[1,2-a]pyridine was obtained via the Chichibabin reaction. The structures of two of the 1,2,3-triazole-indolizine hybrids have been established by single crystal X-ray diffraction. All novel compounds were investigated using UV-vis spectroscopy. Comparison between the fluorescence of 1,2,3-triazole-azaindenes and the fluorescence of analogous azaindenes that lack the 1,2,3-triazole moiety has shown a twofold amplification of fluorescence as a result of incorporation of the 1,2,3-triazole ring system in the structure of the novel hybrids. The 1,2,3-triazole-susbstituted imidazo[1,2-a]pyridine exhibited a stronger fluorescence emission than related 1,2,3-triazole-indolizine hybrids, therefore the former compd sensing ability against metal ions was evaluated. The 1,2,3-triazole-substituted imidazo[1,2-a]pyridine showed selective detection towards Hg2+ and UO2+2 with similar detection limits of approx. 4.5 x 10-5 M. In the experiment, the researchers used Ethyl propiolate(cas: 623-47-2Product Details of 623-47-2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kunkalkar, Rupesh A.’s team published research in Chemical Communications (Cambridge, United Kingdom) in 2019 | CAS: 623-47-2

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Kunkalkar, Rupesh A.; Fernandes, Rodney A.. Electric Literature of C5H6O2. The article was titled 《Lewis acid-catalyzed annulative partial dimerization of 3-aryloxyacrylates to 4-arylchroman-2-ones: synthesis of analogues of tolterodine, RORγ inhibitors and a GPR40 agonist》. The information in the text is summarized as follows:

A beguiling annulative partial dimerization of 3-aryloxyacrylates to 4-arylchroman-2-ones e.g. I catalyzed by Lewis acid (BF3·OEt2) has been developed. The reaction involves two mols. of 3-aryloxyacrylate, resulting in the loss of one propiolate mol. to furnish 4-arylchroman-2-one, an important structural motif found in many natural products. This methodol. has been elaborated to synthesize analogs of tolterodine, RORγ inhibitors and a GPR40 agonist.Ethyl propiolate(cas: 623-47-2Electric Literature of C5H6O2) was used in this study.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zou, Miancheng’s team published research in Journal of Polymer Science (Hoboken, NJ, United States) in 2022 | CAS: 623-47-2

In 2022,Zou, Miancheng; Zhao, Pengkun; Fan, Jilin; Gostl, Robert; Herrmann, Andreas published an article in Journal of Polymer Science (Hoboken, NJ, United States). The title of the article was 《Microgels as drug carriers for sonopharmacology》.Computed Properties of C5H6O2 The author mentioned the following in the article:

The ultrasound-induced cleavage of covalent and non-covalent bonds to activate drugs (sonopharmacol.) is a promising concept to gain control over the action of active pharmaceutical ingredients by an external trigger. Previously, linear polymer architectures bearing drug payloads were exploited for drug release by using the principles of polymer mechanochem. In this work, the carrier design is altered by the polymer topol. to improve the ultrasound-triggered release of covalently anchored drugs from polymer scaffolds. We use microgels crosslinked by mechanoresponsive disulfides and copolymerized with Diels-Alder adducts of furylated payload mols. and acetylenedicarboxylate. Force-induced thiol formation induces a Michael-type addition liberating the payload from the microgels. The use of microgels significantly reduces sonication times compared to linear polymer chains and shields the cargo efficiently from non-triggered activation using ultrasound that produces inertial cavitation at a frequency of 20 kHz as model condition. After reading the article, we found that the author used Ethyl propiolate(cas: 623-47-2Computed Properties of C5H6O2)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pimentel, Luiz Claudio Ferreira’s team published research in Beilstein Journal of Organic Chemistry in 2021 | CAS: 623-47-2

Pimentel, Luiz Claudio Ferreira; Hoelz, Lucas Villas Boas; Canzian, Henayle Fernandes; Branco, Frederico Silva Castelo; Paula de Oliveira, Andressa; Campos, Vinicius Rangel; Silva, Floriano Paes Jr.; Dantas, Rafael Ferreira; Resende, Jackson Antonio Lamounier Camargos; Cunha, Anna Claudia; Boechat, Nubia; Bastos, Monica Macedo published their research in Beilstein Journal of Organic Chemistry in 2021. The article was titled 《The (Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia》.Recommanded Product: Ethyl propiolate The article contains the following contents:

The enzyme tyrosine kinase BCR-Abl-1 is the main mol. target in the treatment of chronic myeloid leukemia and can be competitively inhibited by tyrosine kinase inhibitors such as imatinib. New potential competitive inhibitors were synthesized using the (phenylamino)pyrimidine-pyridine (PAPP) group as a pharmacophoric fragment, and these compounds were biol. evaluated. The synthesis of twelve new compounds was performed in three steps and assisted by microwave irradiation in a 1,3-dipolar cycloaddition to obtain 1,2,3-triazole derivatives substituted on carbon C-4 of the triazole nucleus. All compounds were evaluated for their inhibitory activities against a chronic myeloid leukemia cell line (K562) that expresses the enzyme tyrosine kinase BCR-Abl-1 and against healthy cells (WSS-1) to observe their selectivity. Three compounds showed promising results, with IC50 values between 1.0 and 7.3 μM, and were subjected to mol. docking studies. The results suggest that such compounds can interact at the same binding site as imatinib, probably sharing a competitive inhibition mechanism. One compound showed the greatest interaction affinity for BCR-Abl-1 in the docking studies. The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2Recommanded Product: Ethyl propiolate)

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics