Category: esters-buliding-blocks

Continuous-Flow Synthesis of β-Ketoesters and Successive Reactions in One-Flow using Heterogeneous Catalysis was written by Kandasamy, Mohanraj;Ishitani, Haruro;Kobayashi, Shu. And the article was included in Advanced Synthesis & Catalysis in 2022.Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:

A continuous-flow procedure for the synthesis of β-keto esters R¹C(O)CH₂CO₂R² (R¹ = cyclopropyl, cyclohexyl, n-nonyl, Ph, PhCH:CH, etc., R² = Et; R¹ = PhCH₂CH₂, R² = Et, i-Pr, t-Bu, Ph, PhCH₂) has been developed through Roskamp reaction between aldehydes R¹CHO and α-diazo esters N₂:CHCO₂R² in the presence of a Sn-MCM-41 catalyst. The viability of this methodol. was confirmed with a range of aldehydes and diazo esters and provided good to excellent yields. Catalyst activity was tested over three days (84 h) of operation, and the yield of the desired β-keto ester was maintained between 73 to 89%. The prepared β-keto esters were smoothly transformed into coumarin derivatives and 5-pyrazolone through condensation reactions in a sequential flow. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate).

Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: Ethyl 3-oxo-3-(m-tolyl)propanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of 5-Iodo-1,2,3,4-tetrahydropyridines by Rhodium-Catalyzed Tandem Nucleophilic Attacks Involving 1-Sulfonyl-1,2,3-triazoles and Iodides was written by Man, Zengming;Dai, Haican;Shi, Yinping;Yang, Dongdong;Li, Chuan-Ying. And the article was included in Organic Letters in 2016.Synthetic Route of C10H14O4 This article mentions the following:

Sodium iodide is used for the first time as a nucleophile to trap an α-imino rhodium carbene, which triggers a tandem process involving intermol. nucleophilic attack and intramol. S_N2 reaction. A series of 5-iodo-1,2,3,4-tetrahydropyridines are obtained in high yield, and the synthetic utility of the products is demonstrated in cross-coupling reactions and the construction of biorelated polycyclic compounds In the experiment, the researchers used many compounds, for example, Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9Synthetic Route of C10H14O4).

Diethyl 2-(prop-2-yn-1-yl)malonate (cas: 17920-23-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C10H14O4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Biplot investigation for essential oil yield and chemical compositions under the Deccan Plateau region of southern India in cultivars of Java citronella (Cymbopogon winterianus Jowitt) was written by Kumar, Ashish;Jnanesha, A. C.;Lal, R. K.;Chanotiya, C. S.;Srivastava, Shubham;Pant, Yatish. And the article was included in Industrial Crops and Products in 2022.Formula: C12H20O2 This article mentions the following:

The aromatic grass Java Citronella (Cymbopogon winterianus Jowitt) belongs to the Poaceae family. Citronella essential oil is used to extract the aroma chems. geraniol and citronellal, which can then be converted into citronellol, hydroxy citronellol, synthetic menthol, and geraniol esters. In the Deccan Plateau region of southern India, farmers have a tough time determining which kind would produce high-quality essential oil. As a result, the goal of this study was to evaluate five java citronella cultivars in the Deccan Plateau region of south India and choose the best variety (or varieties) for large-scale production in the Deccan Plateau region. For evaluation, scientists from CSIR-CIMAP, RC, Hyderabad, India, used a three-time replicated randomized complete block design with a plot size of 3.0 m² from 2017 to 2018 and 2018-2019. In Java citronella Java I, Jc-5 was the most stable and high-yielding genotype, though Jc-3 >Jc-2 >Jc-1 in the order performed better in Java citronella Java II type. This is due to the high stability/strong consistency across the years. Based on average performance and stability for higher-quality essential oil yield, these Java citronella genotypes are recommended for large-scale cultivation in the Deccan Plateau region of southern India. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Formula: C12H20O2).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C12H20O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oxidation of monoesters of dicarboxylic acids was written by Blanshtein, I. B.;Moskovich, Yu. L.;Proskuryakov, V. A.. And the article was included in Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation) in 1972.Recommanded Product: 12-Methoxy-12-oxododecanoic acid This article mentions the following:

HO2C(CH2)nCO2Me (n = 7 or 10) were oxidized by O in the presence of KMnO4 and Mn stearate to dicarboxylic acids and their monoesters of lower C content. The product distribution was explained by intramol. chain transfer, coupled with decarboxylation. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0Recommanded Product: 12-Methoxy-12-oxododecanoic acid).

12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Recommanded Product: 12-Methoxy-12-oxododecanoic acid

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A coordinatively saturated sulfate encapsulated in a metal-organic framework functionalized with urea hydrogen-bonding groups was written by Custelcean, Radu;Moyer, Bruce A.;Hay, Benjamin P.. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2005.Recommanded Product: 3-Cyanophenylisocyanate This article mentions the following:

A functional coordination polymer decorated with urea hydrogen-bonding donor groups was designed for optimal binding of sulfate. Self-assembly of a tripodal tris-urea linker, tris{2-(3-cyanophenylureyl)ethyl}amine (L), with Ag₂SO₄ gave a 1-dimensional metal-organic framework, {[Ag₂(L)₂(H₂O)₂](SO₄)}_n (1), that encapsulates SO₄^2- anions via twelve complementary hydrogen bonds, which represents the highest coordination number observed for sulfate in a natural or synthetic host. L and 1 were characterized by x-ray diffraction. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Recommanded Product: 3-Cyanophenylisocyanate).

3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 3-Cyanophenylisocyanate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Structure, thermal and mechanical properties of copoly(ester amide)s based on 2,5-furandicarboxylic acid was written by Zubkiewicz, Agata;Irska, Izabela;Miadlicki, Piotr;Walkowiak, Konrad;Rozwadowski, Zbigniew;Paszkiewicz, Sandra. And the article was included in Journal of Materials Science in 2021.HPLC of Formula: 6683-19-8 This article mentions the following:

In this work, new bio-based copoly(ester amide)s were synthesized by a two-step melt polycondensation process using 2,5-furanedicarboxylic acid di-Me ester (DMFDC), 1,3-propanediol (PDO), and 1,3-diaminopropane (DAP) with different DAP content. The chem. structure of the obtained poly(trimethylene 2,5-furandicarboxylate)-co-poly(propylene furanamide) (PTF-co-PPAF) copolymers was confirmed by NMR (¹H NMR) and Fourier-transform IR (FTIR) spectroscopy. Gas chromatog./mass spectrometry was used to provide more details of the polycondensation process. Thermal properties of the obtained materials were characterized by means of differential scanning calorimetry (DSC), thermogravimetric anal. (TGA), and dynamic-mech. thermal anal. (DMTA). The copolymers were amorphous and their glass transition temperature increased with the increase in the poly(propylene furanamide) (PPAF) content. The synthesized PTF-co-PPAF copolymers exhibited improved thermal and thermo-oxidative stability up to 300°C. In addition, from the performed mech. tests, it was found that along with the increase in PPAF content, Young’s modulus increased, while at the same time, the value of elongation at break decreased. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8HPLC of Formula: 6683-19-8).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 6683-19-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Oral acute toxicity, influence on the gastrointestinal microbiota and in vivo anti-salmonellosis effect of Zizyphus lotus (L.) and Ruta chalepensis (L.) essential oils was written by Bekkar, Nour El Houda;Meddah, Boumediene;Keskin, Bahadir;Sonnet, Pascal. And the article was included in Journal of Applied Biotechnology Reports in 2021.Recommanded Product: 5-Hexyldihydrofuran-2(3H)-one This article mentions the following:

The aim of this study was to evaluate the chem. composition of Zizyphus lotus and Ruta chalepensis essential oils (EOs), the oral acute toxicity, influence on the gastrointestinal microbiota and the in vivo anti-salmonellosis effect. The EOs were isolated using the steam distillation process, and bioactive components were identified by gas chromatog.-mass spectrometry (GC-MS) anal. Oral acute toxicity, influence on the gastrointestinal flora composition and the anti-salmonellosis effect were elucidated using in vivo methods on exptl. animals. The GC-MS allowed us to identify 33 and 58 components in Z. lotus and R. chalepensis, resp. Di-isooctyl phthalate (89.857%) was found to be the major compound identified in Z. lotus. The main compounds in R. chalepensis were 2-undecanone (26.528%) followed by 2-nonanone (13.404%). The LD50 of EOs was found to be greater than 5000 mg/kg. Also, no neg. influence to intestinal microbiota was detected. An important decrease in S. enterica ssp arizonae cells achieving a bactericidal effect was recorded in rats treated with the EOs of both plants at a dose of 400 mg/kg. In parallel, an important significant (P < 0.05) increase in lymphocytes number was observed for all tested animals. A decrease in alk. phosphatase (ALP), amino alanine transferase (ALT) and aspartate aminotransferase (AST) levels was observed Furthermore, a reduced blood erythrocyte sedimentation rate (ESR) was recorded in treated animals. The Z. lotus and R. chalepensis act effectively as anti-salmonellosis agents, which support the use of these plants to cure gastrointestinal infections. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Recommanded Product: 5-Hexyldihydrofuran-2(3H)-one).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 5-Hexyldihydrofuran-2(3H)-one

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Isophthalamide bearing 1-pyrenylethynyl group as a highly fluorescent hydrogen bond motif for anion receptors was written by Kondo, Shin-ichi;Iioka, Jun. And the article was included in Tetrahedron Letters in 2021.Application of 313648-56-5 This article mentions the following:

Isophthalamide-based receptor 2 bearing 1-pyrenylethynyl group I as a fluorophore was prepared for a ratiometric fluorescence sensor for anions. Receptor I showed small hypsochromic shift by UV-vis titrations and ratiometric fluorescence changes upon the addition of anions, in particular biol. important anions such as AcO^–, H₂PO^–₄, and Cl^– with high association constants The high quantum yield of receptor 2 (Φ_F = 0.88) implies that 5-(1-pyrenyl)isophthaloyl amide spacer is a versatile component for various fluorescence receptors. In the experiment, the researchers used many compounds, for example, Dimethyl 5-ethynylisophthalate (cas: 313648-56-5Application of 313648-56-5).

Dimethyl 5-ethynylisophthalate (cas: 313648-56-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 313648-56-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Establishment of Guidelines for the Control of Glycosylation Reactions and Intermediates by Quantitative Assessment of Reactivity was written by Chang, Chun-Wei;Wu, Chia-Hui;Lin, Mei-Huei;Liao, Pin-Hsuan;Chang, Chun-Chi;Chuang, Hsiao-Han;Lin, Su-Ching;Lam, Sarah;Verma, Ved Prakash;Hsu, Chao-Ping;Wang, Cheng-Chung. And the article was included in Angewandte Chemie, International Edition in 2019.Product Details of 4163-60-4 This article mentions the following:

Stereocontrolled chem. glycosylation remains a major challenge despite vast efforts reported over many decades and so far still mainly relies on trial and error. Now it is shown that the relative reactivity value (RRV) of thioglycosides is an indicator for revealing stereoselectivities according to four types of acceptors. Mechanistic studies show that the reaction is dominated by two distinct intermediates: glycosyl triflates and glycosyl halides from N-halosuccinimide (NXS)/TfOH. The formation of glycosyl halide is highly correlated with the production of α-glycoside. These findings enable glycosylation reactions to be foreseen by using RRVs as an α/β-selectivity indicator and guidelines and rules to be developed for stereocontrolled glycosylation. In the experiment, the researchers used many compounds, for example, (2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4Product Details of 4163-60-4).

(2S,3R,4S,5S,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 4163-60-4) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Product Details of 4163-60-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Valorization of Ferulic Acid from Agro-Industrial by-Products for Application in Agriculture was written by Villanueva, Maria Pilar;Gioia, Claudio;Sisti, Laura;Marti, Laura;Llorens-Chiralt, Raquel;Verstichel, Steven;Celli, Annamaria. And the article was included in Polymers (Basel, Switzerland) in 2022.Synthetic Route of C73H108O12 This article mentions the following:

The use of bioplastic mulch in agriculture has increased dramatically in the last years throughout the world. Nowadays, biodegradable materials for mulching films strive to constitute a reliable and more sustainable alternative to classical materials such as polyethylene (PE). The main challenge is to improve their durability in the soil to meet the required service length for crop farming by using benign and sustainable antioxidant systems. Here, we report the design and fabrication of biodegradable materials based on polybutylene (succinate adipate) (PBSA) for mulching applications, incorporating a fully biobased polymeric antioxidant deriving from ferulic acid, which can be extracted from an industrial byproduct. Poly-dihydro (ethylene ferulate) (PHEF) from ferulic acid was synthesized by a two-step polymerization process. It is characterized by improved thermal stability in comparison with ferulic acid monomer and therefore suitable for common industrial processing conditions. Different blends of PBSA and PHEF obtained by melt mixing or by reactive extrusion were prepared and analyzed to understand the effect of the presence of PHEF. The results demonstrate that PHEF, when processed by reactive extrusion, presents a remarkable antioxidant effect, even in comparison with com. additives, preserving a high level of the mech. properties of the PBSA matrix without affecting the biodegradable character of the blend. In the experiment, the researchers used many compounds, for example, 2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8Synthetic Route of C73H108O12).

2,2-Bis(((3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoyl)oxy)methyl)propane-1,3-diyl bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanoate) (cas: 6683-19-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C73H108O12

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics