Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. 99769-19-4, formula is C8H9BO4, Name is 3-(Methoxycarbonyl)phenylboronic acid. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Computed Properties of 99769-19-4.
Luo, Na;Fang, Xiaoyu;Su, Mingbo;Zhang, Xinwen;Li, Dan;Li, Honglin;Li, Shiliang;Zhao, Zhenjiang research published 《 Design, Synthesis and SAR Studies of Novel and Potent Dipeptidyl Peptidase 4 Inhibitors》, the research content is summarized as follows. To discover novel and potent DPP-4 inhibitors, three series of compounds I [R = H, Br, MeO(O)C, etc.] , II, III [R1 = Br, Ph, 2,4-difluorophenyl, etc.] and IV [R2 = H, Br, MeO; R3 = H, Br, CN, HO(O)C] were designed and synthesized in this study based on previously identified novel scaffold of 2-phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine. Among the designed compounds, IV [R2 = H, R3 = CN] was the most potent one with an IC50 value of 16.00 nM. Besides, IV [R2 = H, R3 = CN] (5 mg/kg) displayed a moderate glucose tolerance capability in ICR mice. Structure-activity-relationship (SAR) studies were discussed in detail, which was constructive for further optimization.
Computed Properties of 99769-19-4, 3-Methoxycarbonylphenylboronic acid is a useful research compound. Its molecular formula is C8H9BO4 and its molecular weight is 179.97 g/mol. The purity is usually 95%.
3-Methoxycarbonylphenylboronic acid is a reactanct that has been involved in a variety of applications. For instance, it has been used in Suzuki-Miyaura cross-coupling, Iterative cross-coupling of boronate building blocks, cross-coupling with aryl/ alkenyl sulfonates, synthesis of symmetrical biaryls via CuCl catalyzed homocoupling, trifluoromethylation, and cyanation just to name a few of its many uses.
3-Methoxycarbonylphenylboronic acid is a boronate ligand that has been shown to have an interaction with the nitrogen atoms in amines. This compound is used for the Suzuki coupling reaction, which is a chemical reaction between an organoboron compound and an organic electrophile. 3-Methoxycarbonylphenylboronic acid has a helical structure that can be seen by FTIR spectroscopy and it has potent inhibitory activity., 99769-19-4.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics