Category: 94-02-0

Xie, Caixia; Li, Songhua; Li, Yunyi; Ma, Chen published the artcile< An efficient route for the synthesis of N-(1H-benzo[d]imidazol-2-yl)benzamide derivatives promoted by CBr4 in one pot>, Synthetic Route of 94-02-0, the main research area is benzoimidazolyl benzamide preparation.

A metal-free one-pot method for the synthesis of N-(1H-benzo[d]imidazol-2-yl)benzamide derivatives such as I [R1 = Ph, 4-MeC6H4, 1-naphthyl, etc.; R2 = Me, Et, Ph] and N-(1H-imidazol-2-yl)benzamide derivatives II [R3 = 4-ClC6H4, 4-MeOC6H4, 4-CF3C6H4, etc.; R4 = Et, Me] was proposed mediated by CBr4. The reaction went through ring formation and opening processes with only two protons leaving and the thermodynamically favorable products were selectively formed in moderate to good yields. Easily accessible starting materials, simple operations and high atom economy made this strategy a potential and useful method in organic and pharmaceutical chem.

Tetrahedron published new progress about Atom economy. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Synthetic Route of 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An, Xiaoying; Gao, Lei; Wang, Mingliang; Wu, Haitao; Wang, Lanzhi published the artcile< One-pot synthesis of 1,5-benzodiazepine-2,3-dicarboxylates via three-component domino reactions in the presence of γ-Fe2O3@SiO2/Ce(OTf)3>, Name: Ethyl 3-oxo-3-phenylpropanoate, the main research area is iron oxide silica supported cerium triflate catalyst preparation; benzodiazepine dicarboxylate green preparation; phenylenediamine beta carbonyl ester ethyl glyoxylate three component domino; methyl benzodiazepine dicarboxylate green preparation; ethyl pyruvate phenylenediamine beta carbonyl ester three component domino.

Novel, efficient and environmentally friendly approaches was developed for the synthesis of 1,5-benzodiazepine-2,3-dicarboxylates I [R1 = H, Me, Cl, Br; R2 = Me, Et, Ph; R3 = Me, Et, Pr] and II by one-pot three-component domino reactions in the presence of a catalytic amount of γ-Fe2O3@SiO2/Ce(OTf)3 in EtOH at ambient temperature A total of synthesized 2,5-dihydro-1H-1,5-benzodiazepine-2,3-dicarboxylates I and 2-methyl-2,3-dihydro-1H-1,5-benzodiazepine-2,3-dicarboxylates II with enamine or imine structure of the heterocycle, resp., were obtained in good yields by reacting substituted 1,2-phenylenediamine, β-carbonyl esters and Et glyoxylate or Et pyruvate. One-pot reactions were successfully realized to form one new cycle and four new bonds (one C-C, two C-N, one C=C or two C-C, one C-N, one C=N). The salient features of this reaction included short reaction time, mild reaction conditions, moderate to excellent yields, recyclability of the catalyst, and wide substrate scope.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about Aromatic diamines Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Name: Ethyl 3-oxo-3-phenylpropanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Heravi, Majid M.; Malakooti, Reihaneh; Kafshdarzadeh, Kosar; Amiri, Zahra; Zadsirjan, Vahideh; Atashin, Hassan published the artcile< Supported palladium oxide nanoparticles in Al-SBA-15 as an efficient and reusable catalyst for the synthesis of pyranopyrazole and benzylpyrazolyl coumarin derivatives via multicomponent reactions>, Computed Properties of 94-02-0, the main research area is aluminum SBA15 supported palladium oxide nanocatalyst preparation; dihydropyranopyrazole green preparation; pyrazolyl coumarin green preparation.

An eco-friendly method for diversity-oriented synthesis of substituted dihydropyrano[2,3-c]pyrazoles such as I [R = H, Ph; R1 = Me, 4-ClC6H4, 4-O2NC6H4, etc.; R2 = H, Me; X = CN, CO2Et] and pyrazolyl-coumarins IV [R4 = H, Ph; R5 = Ph, 4-MeOC6H4, 3-O2NC6H4, 4-O2NC6H4, 4-MeC6H4] had been achieved via one-pot and multicomponent reaction in the presence of PdO/Al-SBA-15 as an efficient and recyclable catalyst in H2O/EtOH under reflux conditions. The significant merits of this method were wide scope, high yields of the desired products, short reaction times and simple workup procedure. In addition, this nanocatalyst was simply recovered and reused five times without significant loss in catalytic activity and also performance.

Research on Chemical Intermediates published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Computed Properties of 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Hua; Wang, Zheyuan; Wang, Zirui; Chu, Yunpeng; Wang, Shuncheng; Hui, Xin-Ping published the artcile< Visible-Light-Mediated Formal Carbene Insertion Reaction: Enantioselective Synthesis of 1,4-Dicarbonyl Compounds Containing All-Carbon Quaternary Stereocenter>, HPLC of Formula: 94-02-0, the main research area is dicarbonyl compound preparation enantioselective; diketone diazoester carbene insertion visible light.

Authors developed an efficient visible-light-mediated formal carbene insertion reaction of 1,3-diketones with diazoesters for the construction of enantioenriched 1,4-dicarbonyl compounds with a quaternary carbon center. Combining visible light and a Bronsted acid catalyst, chiral 1,4-dicarbonyl compounds were achieved in good yields with high enantioselectivities by a photochem. carbene transfer protocol.

ACS Catalysis published new progress about Diazo compounds, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, HPLC of Formula: 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gao, Xinyue; Shi, Xiaoqing; Yang, Dianna; Jin, Hao; Zhou, Xinghua; Meng, Tianzi; Li, Xin; Jia, Zixing; Zhang, Xuewen; Wu, Zeyu; Wang, Chunnong; Zeng, Taining; Liu, Li; Ai, Chao; Zhu, Huajie published the artcile< Highly efficient axially biscarboline ethers as catalysts used in 1,2- and 1,4-transfer hydrogenations of ketimines and β-enamino esters>, Formula: C11H12O3, the main research area is arylaminopropenoate enantioselective transfer hydrogenation axial chiral catalyst; arylaminopropanoate ethyl stereoselective preparation; ketimine axial chiral catalyst enantioselective transfer hydrogenation; phenylalkylaniline stereoselective preparation.

A series of new axial chiral biscarboline ethers were synthesized using L-tryptophan amino acid after dehydrogenation and oxidations using m-CPBA. These diastereoisomers can be obtained by column chromatog. and used as catalysts in asym. hydrogenation reactions of β-enamine esters and ketimines. Chiral catalysts (R)- and (S)-I exhibited very high enantioselectivity in the reactions. For example, a high up to 98% ee was achieved in the enantioselective hydrogenations when only 1 mol% of catalyst was used.

Journal of Molecular Structure published new progress about Amino acid esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Formula: C11H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xia, Biao; Chen, Wenjun; Zhao, Qiongli; Yu, Wenquan; Chang, Junbiao published the artcile< Synthesis of Functionalized Imidazolium Salts via Iodine-Mediated Annulations of Enamines>, SDS of cas: 94-02-0, the main research area is imidazolium salt preparation; enamine preparation annulation iodine.

A novel annulation reaction of two enamine mols. with iodine under basic conditions to form 4-functionalized imidazolium salts has been established. In this reaction, iodine acts as both an iodinating reagent and a Lewis acid catalyst. Features of this synthetic method include facilitative preparation of substrates, no use of transition metals, mild reaction conditions, simplicity of operation, and gram scale synthesis.

Organic Letters published new progress about Cyclization. 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, SDS of cas: 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asahara, Haruyasu; Kikuchi, Shuhei; Unno, Yuto; Yokoyama, Soichi; Yoshioka, Kotaro; Tani, Shinki; Umezu, Kazuto; Nishiwaki, Nagatoshi published the artcile< A Facile Synthesis of Oxiranes Possessing Three or Four Carbonyl Groups>, Quality Control of 94-02-0, the main research area is carbonylated oxirane preparation; diethyl mesoxalate bromoketone condensation.

Tri-carbonylated oxiranes I [R = H; Ar = Ph, 4-MeC6H4, 4-BrC6H4, etc.] were efficiently synthesized via condensation of vicinal tricarbonyl compound with α-bromoketones in the presence of a base. This protocol was applicable to α-bromo-β-keto esters to give tetra-carbonylated oxiranes I [R = CO2Et] from which trifunctionalized bromoalkene was competitively formed. The ratio of compounds I was influenced by the solvent and reaction temperature Synthesis of 2,3-bis-organochalcogenyl-benzo[b]chalcogenophenes promoted by oxone.

Current Organic Chemistry published new progress about Aryl ketones Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Quality Control of 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Heng; Guo, Tianyun; Wu, Mingzhong; Huo, Xing; Tang, Shouchu; Wang, Xiaolei; Liu, Jian published the artcile< 4CzIPN catalyzed photochemical oxidation of benzylic alcohols>, Reference of 94-02-0, the main research area is aldehyde ketone preparation green chem 4CzlPN catalyst; benzylic primary secondary alc photoredox oxidation.

A green photoredox oxidation of benzylic primary and secondary alcs. to aldehydes and ketones with air as an oxidant was reported. The oxidation shows broad substrate scope and excellent selectivity over benzylic alcs. to the aliphatic alcs. Further mechanistic studies revealed a quinuclidine mediated HAT process, and blue LEDs promoted 4CzlPN (1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene) photoredox cycle were involved in the oxidation

Tetrahedron Letters published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Reference of 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Hua; Wang, Zheyuan; Wang, Zirui; Chu, Yunpeng; Wang, Shuncheng; Hui, Xin-Ping published the artcile< Visible-Light-Mediated Formal Carbene Insertion Reaction: Enantioselective Synthesis of 1,4-Dicarbonyl Compounds Containing All-Carbon Quaternary Stereocenter>, HPLC of Formula: 94-02-0, the main research area is dicarbonyl compound preparation enantioselective; diketone diazoester carbene insertion visible light.

Authors developed an efficient visible-light-mediated formal carbene insertion reaction of 1,3-diketones with diazoesters for the construction of enantioenriched 1,4-dicarbonyl compounds with a quaternary carbon center. Combining visible light and a Bronsted acid catalyst, chiral 1,4-dicarbonyl compounds were achieved in good yields with high enantioselectivities by a photochem. carbene transfer protocol.

ACS Catalysis published new progress about Diazo compounds, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, HPLC of Formula: 94-02-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gao, Xinyue; Shi, Xiaoqing; Yang, Dianna; Jin, Hao; Zhou, Xinghua; Meng, Tianzi; Li, Xin; Jia, Zixing; Zhang, Xuewen; Wu, Zeyu; Wang, Chunnong; Zeng, Taining; Liu, Li; Ai, Chao; Zhu, Huajie published the artcile< Highly efficient axially biscarboline ethers as catalysts used in 1,2- and 1,4-transfer hydrogenations of ketimines and β-enamino esters>, Formula: C11H12O3, the main research area is arylaminopropenoate enantioselective transfer hydrogenation axial chiral catalyst; arylaminopropanoate ethyl stereoselective preparation; ketimine axial chiral catalyst enantioselective transfer hydrogenation; phenylalkylaniline stereoselective preparation.

A series of new axial chiral biscarboline ethers were synthesized using L-tryptophan amino acid after dehydrogenation and oxidations using m-CPBA. These diastereoisomers can be obtained by column chromatog. and used as catalysts in asym. hydrogenation reactions of β-enamine esters and ketimines. Chiral catalysts (R)- and (S)-I exhibited very high enantioselectivity in the reactions. For example, a high up to 98% ee was achieved in the enantioselective hydrogenations when only 1 mol% of catalyst was used.

Journal of Molecular Structure published new progress about Amino acid esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 94-02-0 belongs to class esters-buliding-blocks, and the molecular formula is C11H12O3, Formula: C11H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics