Category: 936-03-8

The author of 《Efficient and Practical Arene Hydrogenation by Heterogeneous Catalysts under Mild Conditions》 were Maegawa, Tomohiro; Akashi, Akira; Yaguchi, Kiichiro; Iwasaki, Yohei; Shigetsura, Masahiro; Monguchi, Yasunari; Sajiki, Hironao. And the article was published in Chemistry – A European Journal in 2009. Synthetic Route of C8H14O3 The author mentioned the following in the article:

An efficient and practical arene hydrogenation procedure based on the use of heterogeneous platinum group catalysts has been developed. Rh/C is the most effective catalyst for the hydrogenation of the aromatic ring, which can be conducted in iPrOH under neutral conditions and at ordinary to medium H2 pressures (<10 atm). A variety of arenes such as alkylbenzenes, benzoic acids, pyridines, furans, are hydrogenated to the corresponding cyclohexyl and heterocyclic compounds in good to excellent yields. The use of Ru/C, less expensive than Rh/C, affords an effective and practical method for the hydrogenation of arenes including phenols. Both catalysts can be reused several times after simple filtration without any significant loss of catalytic activity. After reading the article, we found that the author used Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Synthetic Route of C8H14O3)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Synthetic Route of C8H14O3 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 1984,Australian Journal of Chemistry included an article by Babidge, Peter J.; Massy-Westropp, Ralph A.. Computed Properties of C8H14O3. The article was titled 《New eudesmane sesquiterpenoids from Eremophila scoparia》. The information in the text is summarized as follows:

Three new eudesmane sesquiterpenoids were isolated from E. scoparia and identified as (4aR,6S,7S,8aS)-7-hydroxy-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-4a,5,6,7,8,8a-hexahydronaphthalen-2(1H)-one, (4aS,6S,7S,8aS)-7-hydroxy-6-(1-hydroxy-1-methylethyl)-4,8a-dimethyl-4a,5,6,7,8,8a-hexahydronaphthalen-2(1H)-one, and (2S,3S,4aR,8aS)-3-(1-hydroxy-1-methylethyl)-5,8a-dimethyl-7-oxo-1,2,3,4,4a,7,8,8a-octahydronaphthalen-2-yl acetate. The results came from multiple reactions, including the reaction of Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Computed Properties of C8H14O3)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Computed Properties of C8H14O3 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Intramolecular hydrogen bonds. V. Aliphatic hydroxy carboxylates》 was published in Bulletin of the Chemical Society of Japan in 1965. These research results belong to Mori, Nobuo; Omura, Satoshi; Kobayashi, Norihiko; Tsuzuki, Yojiro. Recommanded Product: Cis-methyl 2-hydroxycyclohexanecarboxylate The article mentions the following:

cf. CA 63, 17169d. The ir spectra of a number of hydroxy carboxylates in CCl4 were measured and the bands were explained on the basis of the possible rotational isomers around the Cα-O axis, as shown in I, II, IIIa, and IIIb and their mirror images. The aliphatic esters studied are of the type R1R2C(OH)(CH2)n-1CO2R (IV) (n, R1, R2, and R given): 1, H, H, Et (IVa); 1, Me, H, Me (IVb) (b46 68°); 1, Me, H, Et (IVc); 1, Me, H, iso-Pr (IVd) (b40 74°); 1, Me, Me, Et (IVe); 2, H, H, Me (IVf) (b15 74°); 2, H, H, Et (IVg); 2, Me, H, Me (IVh) (b13 67°); 2, Me, H, Et (IVi); 2, Me, Me, Me (IVj) (b15 67°); 3, Me, H, Et (IVk) (b2 85-7°); 5, H, H, Et (IVl) (b20 138°); 6, H, H, Et (b15 145°); 8, H, H, Et (b2 131-2°); 9, H, H, Et; 10, H, H, Et. The following cyclic esters (V) were studied (R and position of OH given): Me, 1 (Va) (b10 87°, n25D 1.4585); Me, cis-2 (b14 103°, n25D 1.4637); Et, cis-2; Me, trans-2 (b14 112.5°, n25D 1.4634); Et, trans-2; Me, cis-3 (Vb) (b5 113-15°, n25D 1.4658); Me, trans-3 (b6 111-12° n25D 1.4657); Me, cis-4 (Vc) (b12 128°, n25D 1.4684); Me, trans-4 (b12 125°, n25D 1.4669). The α-OH esters IVa-e and Va showed a strong band due to H bonding with carbonyl oxygen (form I) and a weak one due to H bond with ether oxygen (form II). The frequency of the latter band decreased with increasing number of Me groups attached to the α-carbon atom. The ratio of the absorbance of the weak band to that of the strong band (Dw/Ds) was substantially constant in α-esters, but decreased as the alc. alkyl portion of the ester group increased in bulk or in the number of C atoms. The relatively high ratio for Va was explained in terms of possible steric repulsion between the axial H on C-2 and C-6 and the alkoxy group. Of the β-OH esters studied, IVf and IVg showed bands corresponding to forms I, IIIa and IIIb, while IVh-j showed bands corresponding to forms I, II and a mixture of IIIa and IIIb. The Me group on the β-carbon atom sterically serve to make the OH and the ester group closer together; the non-bonded forms IIIa and IIIb decrease in proportion, and the form II comes into existence. IVk and IV1 showed 3 bands corresponding to forms I, IIIa, and a mixture of IIIa and IIIb. Higher ω-hydroxy esters formed no H-bonding. The absence of H-bonding in Vc was due to the instabilization resulting from assuming the boat or twist conformation. The orientation of the ester group in its 1,3-diaxial chair conformation is unfavorable for H-bonding in Vb. Comparison of the H-bonding frequencies of the hydroxy esters with α,ω-alkanediols and ω-methoxy alkanols of the series RO(CH2)nOH, where R = Me or H, indicated, the frequency corresponding to form I in esters was much lower, but for form II, it was higher than those of the other series, when the number of members in a ring to be formed through H bonding was equal to 5. When the ring consists of six members or more, the frequencies for forms I and II of the esters were higher than those of both the alkanol series. The experimental part of the paper was very detailed, including the reaction process of Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Recommanded Product: Cis-methyl 2-hydroxycyclohexanecarboxylate)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.Recommanded Product: Cis-methyl 2-hydroxycyclohexanecarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kitamura, M.; Tokunaga, M.; Noyori, R. published an article on January 13 ,1993. The article was titled 《Quantitative expression of dynamic kinetic resolution of chirally labile enantiomers: stereoselective hydrogenation of 2-substituted 3-oxo carboxylic esters catalyzed by BINAP-ruthenium(II) complexes》, and you may find the article in Journal of the American Chemical Society.Product Details of 936-03-8 The information in the text is summarized as follows:

Hydrogenation of chirally unstable 2-substituted 3-oxo carboxylic esters gives a mixture of four stereoisomeric hydroxy esters. Use of BINAP-Ru(II) complex catalysts allows selective production of one stereoisomer among four possible isomers. The stereoselectivity obtained by the dynamic kinetic resolution depends on facile in situ racemization of the substrates, efficient chirality recognition ability of the catalysts, and the structures of the ketonic substrates. The factors controlling the efficiency of the stereoselective hydrogenation are exptl. determined by reaction of racemic oxo esters using enantiomerically pure and racemic BINAP complexes. Quant. expression of the dynamic kinetic resolution has been made by defining the product partition coefficients (w, x, y, and z), the relative reactivities of the enantiomeric substrates (kfast/kslow), and the relative ease with which stereoinversion and hydrogenation take place (kinv/kfast). The validity of the equations has been demonstrated by the graphical exhibition of the enantioselectivity and diastereoselectivity as a function of conversion of the substrates. The experimental part of the paper was very detailed, including the reaction process of Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Product Details of 936-03-8)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Product Details of 936-03-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Photochemistry of two β,β’-epoxy ketones, 3-oxatricyclo[3.2.1.02,4]octan-8-one and 3-oxatricyclo[3.3.1.02.4]nonan-9-one. Intramolecular reactions of α,β-unsaturated aldehydo ketenes》 was published in Journal of Organic Chemistry in 1978. These research results belong to Ayral-Kaloustian, Semiramis; Wolff, Steven; Agosta, William C.. COA of Formula: C8H14O3 The article mentions the following:

Photolysis of epoxy ketone I in C6H6 leads to OHCCH:CHCH2CH2CH:CO (II) and β-lactone III as primary products. Subsequent addition of MeOH furnishes IV and V. Secondary photolysis of II yields the cycloaddition product VI. Photolysis of I in C6H6 containing 3% MeOH gives IV directly, along with VII. Similar irradiation of epoxy ketone VIII leads to OHCCH:CH(CH2)3CH:CO, which reacts with MeOH to give the aldehydo esters IX and X. The results came from multiple reactions, including the reaction of Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8COA of Formula: C8H14O3)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.COA of Formula: C8H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Carbon-13 NMR spectra of some methyl cyclohexanecarboxylates》 was written by Senda, Yasuhisa; Ishiyama, Junichi; Imaizumi, Shin. Application of 936-03-8 And the article was included in Bulletin of the Chemical Society of Japan in 1976. The article conveys some information:

13C NMR spectra of a series of 18 stereoisomeric substituted Me cyclohexanecarboxylates were determined The resonances for ring C atoms of the isomers in which both the methoxycarbonyl and the other groups had equatorial orientations usually appeared at a field lower than those of the isomers in which 1 of the 2 substituents had axial orientation. No appreciable difference in shift due to configurational change was observed in the resonances for the substituents. Observed chem. shifts were compared with predicted values. In the experimental materials used by the author, we found Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Application of 936-03-8)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.Application of 936-03-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Stereochemical studies, XXVII. Studies on 2-hydroxycycloalkanoates, VI》 were Bernath, Gabor; Sohar, Pal; Lang, Kornelia L.; Gondos, Gyorgy; Gera, Lajos; Pal, A.. And the article was published in Acta Chimica Academiae Scientiarum Hungaricae in 1977. Reference of Cis-methyl 2-hydroxycyclohexanecarboxylate The author mentioned the following in the article:

The saponification kinetics of I (R = Et, n = 1, 2, 3, 4) and II (R = Et, R1 = OH, n = 1, 2, 3, 4) in 70% aqueous dioxane are accelerated by a factor of 10-21 by the neighboring OH group with respect to II [R = Et, R1 = H (III), n = 1, 2, 3, 4]; the ratio of reaction rates occurring with or without OH participation is ester concentration dependent. There is no difference between the cis and trans isomers in the cyclopentane or cycloheptane series; I (R = Et, n = 4) reacts faster than II (R = Et, R1 = OH, n = 4) while I (R = Et, n = 2) reacts slower then II (R = Et, R1 = OH, n = 2). The isokinetic temperatures for the saponification of I and II (R1 = OH) is 151 ± 12 K. The slope with III in steeper than that with I (R = Et) or II (R = Et, R1 = OH) indicating that the 2 reactions occur by different mechanisms. The rate enhancing effect of the neighboring OH group is due to mostly to solvent sorting by the OH group. H-bonding in I and II (R1 = OH) and the IR and NMR of I (R = Et, Me) and II (R = Me, Et; R1 = OH) are discussed. After reading the article, we found that the author used Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Reference of Cis-methyl 2-hydroxycyclohexanecarboxylate)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Reference of Cis-methyl 2-hydroxycyclohexanecarboxylate Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solladie-Cavallo, A.; Baram, A.; Choucair, E.; Norouzi-Arasi, H.; Schmitt, M.; Garin, F. published their research in Journal of Molecular Catalysis A: Chemical on August 1 ,2007. The article was titled 《Heterogeneous hydrogenation of substituted phenols over Al2O3 supported ruthenium》.HPLC of Formula: 936-03-8 The article contains the following contents:

Catalytic heterogeneous hydrogenation over Ru/Al2O3 of mono- and di-substituted phenols works and provides mixtures of the two or four possible isomers. Although cis and all-cis isomers (corresponding to all-syn H2 additions) are less stable, they are always major. Also large alkyl substituents and carbomethoxy groups have a tendency to increase the diastereoselectivity and formation of larger amounts of the trans isomers is related to the presence of an OH group thus supporting intermediate formation of the corresponding ketone as already suggested. After reading the article, we found that the author used Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8HPLC of Formula: 936-03-8)

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.HPLC of Formula: 936-03-8 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vasickova, Sona; Tichy, Milos published an article on February 28 ,1979. The article was titled 《Stereochemical studies. LXXXVIII. Infrared spectra and conformation of substituted methyl cyclohexanecarboxylates and 2-hydroxycyclohexanecarboxylates》, and you may find the article in Collection of Czechoslovak Chemical Communications.Synthetic Route of C8H14O3 The information in the text is summarized as follows:

The IR of the C:O and OH groups in thirty-two Me alkylcyclohexane- and alkyl-trans-decalin-2-carboxylates and their vicinal OH derivatives were computer assigned to the appropriate conformers. The conformational equilibrium thermodn. and attractive interaction between equatorial OH and equatorial CO2Me groups were calculated in Me trans-2-hydroxy-cis-4-isopropylcyclohexanecarboxylate.Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8Synthetic Route of C8H14O3) was used in this study.

Cis-methyl 2-hydroxycyclohexanecarboxylate(cas: 936-03-8) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Synthetic Route of C8H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics