Category: 93108-07-7

Autoxidation in the presence of alcohols and protons. III. Autoxidation of cyclenes, hydroarenes, and hydroheterocycles was written by Treibs, Wilhelm;Schoellner, Roll. And the article was included in Chemische Berichte in 1961.Computed Properties of C11H14O3 This article mentions the following:

Cyclohexene (I) and Tetralin (II) yield by autoxidation in the presence of alcs. and protons 浼?ketones and also under cleavage of the C-C bond neighboring the place of the O attack (CH₂CH₂-CHO)₂ (III) and o-HOC₆H₄(CH₂)₃CHO (IV) which are stabilized as the acetals. The autoxidation of I yielded also as the result of a Prilesehayev-type reaction o-methoxycyclohexanol (V), 2-methoxy-1,3-cyclohexanediol (VI), and 3-methoxycyclohexene (VII). 1,2,3,4,10,11-Hexahydrodiphenylene oxide (VIII) yields similarly 1,2,3,4,11,12hexahydro-12-methoxydibenzodioxane (IX) and 1,2,3,4,10,11-hexahydro-10-methoxydiphenylene oxide (X). I (200 g.), 1500 cc. absolute MeOH, and 3 cc. concentrated H₂SO₄ irradiated 120 hrs. under O at 60鎺?with ultraviolet light, neutralized with NaHCO₃, decanted, and fractionated gave 7-8 g. VII, b. 135-6鎺? n¹_D² 1.463, 14 g. distillate, b₁₆ 67-9鎺?n¹_D⁰ 1.4700, which chromatographed yielded cyclohexen-3-one, n²_D⁰ 1.4798 (2,4-dinitrophenylhydrazone, m. 164-6鎺?, and V, n¹_D⁰ 1.4612, 3-4 g. cyclic di-Me acetal of III, b₁₅ 82-4鎺? n²_D⁰ 1.432 [bis(2,4-dinitrophenylhydrazone) of III, m. 216-17鎺砞, and 29 g. distillate, b₁₅ 98-118鎺? which chromatographed gave 50-5% bis(dimethyl acetal) of III, b₁₂ 103-8鎺?26-30% MeO₂C(CH₄)₄CH(OMe)₂ (2,4-dinitrophenylhydra zone m. 101鎺?, and 18-20% VI, n²_D⁰ 1.468. II (200 g.), 1500 cc. absolute MeOH, and 2.5 cc. concentrated H₂SO₄ irradiated 240 hrs. under O at 60鎺? and the crude product (30 g.) distilled gave 11 g. 浼?tetralone, b₁₂ 130鎺?(2,4-dinitrophenylhydrazone m. 257-8鎺?, 10 g. di-Me acetal of IV (2,4-dinitrophenylhydrazone of IV m. 148鎺?, and 15-20% o-HOC₆H₄(CH₂)₃CO₂Me. Diphenylene oxide in absolute EtOH hydrogenated at 120鎺?110 atm. gave 45-50% VIII, b_0.04 51-2鎺? n²_D⁰ 1.545, and some perhydrodiphenylene oxide, b₂₀ 130-4鎺? and 0-phenylcyclohexanol, b₂0 149-53鎺? VIII (150 g.) in 1500 cc. absolute MeOH and 2.5 cc. concn H₂SO₄ autoxidized under O during 96 hrs. at 60鎺? neutralized with NH₃, concentrated, and distilled gave a crude product, b_0.3 93-6鎺? n²_D⁰ 1.541, which chromatographed on Al₂O₃ yielded X, n²_D⁰ 1.5533, and IX. X (1 g.), 10 cc. 2N HCl, and 5 cc. MeOH refluxed 6 hrs., neutralized with NH₃, concentrated, and chromatographed gave the 10-OH analog of X, m. 102鎺? IX (1 g.), 20 cc. 0.1N HCl, and 5 cc. MeOH refluxed 6 hrs., and the crude product chromatographed on Al₂O₂ yielded 0.6 g. pure IX, m. 64-8鎺? n⁸_D⁰ 1.542, and an unidentified material. Cumene (150 g.) autoxidized under the usual conditions during 360 hrs. gave 10-12 g. product containing 12-15% AcPh (2,4-dinitrophenylhydrazone m. 247鎺?. Com. cumene hydroperoxide (60%) (20 g.) added dropwise to 0.5 cc. concentrated H₂SO₄ in 250 cc. absolute MeOH, cooled, neutralized with NaHCO₃, and fractionated yielded 6.7 g. cumene and 1.4 g. AcPh. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7Computed Properties of C11H14O3).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Autoxidation in the presence of alcohols and protons. III. Autoxidation of cyclenes, hydroarenes, and hydroheterocycles was written by Treibs, Wilhelm;Schoellner, Roll. And the article was included in Chemische Berichte in 1961.Computed Properties of C11H14O3 This article mentions the following:

Cyclohexene (I) and Tetralin (II) yield by autoxidation in the presence of alcs. and protons 伪-ketones and also under cleavage of the C-C bond neighboring the place of the O attack (CH₂CH₂-CHO)₂ (III) and o-HOC₆H₄(CH₂)₃CHO (IV) which are stabilized as the acetals. The autoxidation of I yielded also as the result of a Prilesehayev-type reaction o-methoxycyclohexanol (V), 2-methoxy-1,3-cyclohexanediol (VI), and 3-methoxycyclohexene (VII). 1,2,3,4,10,11-Hexahydrodiphenylene oxide (VIII) yields similarly 1,2,3,4,11,12hexahydro-12-methoxydibenzodioxane (IX) and 1,2,3,4,10,11-hexahydro-10-methoxydiphenylene oxide (X). I (200 g.), 1500 cc. absolute MeOH, and 3 cc. concentrated H₂SO₄ irradiated 120 hrs. under O at 60掳 with ultraviolet light, neutralized with NaHCO₃, decanted, and fractionated gave 7-8 g. VII, b. 135-6掳, n¹_D² 1.463, 14 g. distillate, b₁₆ 67-9掳 n¹_D⁰ 1.4700, which chromatographed yielded cyclohexen-3-one, n²_D⁰ 1.4798 (2,4-dinitrophenylhydrazone, m. 164-6掳), and V, n¹_D⁰ 1.4612, 3-4 g. cyclic di-Me acetal of III, b₁₅ 82-4掳, n²_D⁰ 1.432 [bis(2,4-dinitrophenylhydrazone) of III, m. 216-17掳], and 29 g. distillate, b₁₅ 98-118掳, which chromatographed gave 50-5% bis(dimethyl acetal) of III, b₁₂ 103-8掳 26-30% MeO₂C(CH₄)₄CH(OMe)₂ (2,4-dinitrophenylhydra zone m. 101掳), and 18-20% VI, n²_D⁰ 1.468. II (200 g.), 1500 cc. absolute MeOH, and 2.5 cc. concentrated H₂SO₄ irradiated 240 hrs. under O at 60掳, and the crude product (30 g.) distilled gave 11 g. 伪-tetralone, b₁₂ 130掳 (2,4-dinitrophenylhydrazone m. 257-8掳), 10 g. di-Me acetal of IV (2,4-dinitrophenylhydrazone of IV m. 148掳), and 15-20% o-HOC₆H₄(CH₂)₃CO₂Me. Diphenylene oxide in absolute EtOH hydrogenated at 120掳/110 atm. gave 45-50% VIII, b_0.04 51-2掳, n²_D⁰ 1.545, and some perhydrodiphenylene oxide, b₂₀ 130-4掳, and 0-phenylcyclohexanol, b₂0 149-53掳. VIII (150 g.) in 1500 cc. absolute MeOH and 2.5 cc. concn H₂SO₄ autoxidized under O during 96 hrs. at 60掳, neutralized with NH₃, concentrated, and distilled gave a crude product, b_0.3 93-6掳, n²_D⁰ 1.541, which chromatographed on Al₂O₃ yielded X, n²_D⁰ 1.5533, and IX. X (1 g.), 10 cc. 2N HCl, and 5 cc. MeOH refluxed 6 hrs., neutralized with NH₃, concentrated, and chromatographed gave the 10-OH analog of X, m. 102掳. IX (1 g.), 20 cc. 0.1N HCl, and 5 cc. MeOH refluxed 6 hrs., and the crude product chromatographed on Al₂O₂ yielded 0.6 g. pure IX, m. 64-8掳, n⁸_D⁰ 1.542, and an unidentified material. Cumene (150 g.) autoxidized under the usual conditions during 360 hrs. gave 10-12 g. product containing 12-15% AcPh (2,4-dinitrophenylhydrazone m. 247掳). Com. cumene hydroperoxide (60%) (20 g.) added dropwise to 0.5 cc. concentrated H₂SO₄ in 250 cc. absolute MeOH, cooled, neutralized with NaHCO₃, and fractionated yielded 6.7 g. cumene and 1.4 g. AcPh. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7Computed Properties of C11H14O3).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Autoxidation in the presence of alcohols and protons. III. Autoxidation of cyclenes, hydroarenes, and hydroheterocycles was written by Treibs, Wilhelm;Schoellner, Roll. And the article was included in Chemische Berichte in 1961.Computed Properties of C11H14O3 This article mentions the following:

Cyclohexene (I) and Tetralin (II) yield by autoxidation in the presence of alcs. and protons α-ketones and also under cleavage of the C-C bond neighboring the place of the O attack (CH₂CH₂-CHO)₂ (III) and o-HOC₆H₄(CH₂)₃CHO (IV) which are stabilized as the acetals. The autoxidation of I yielded also as the result of a Prilesehayev-type reaction o-methoxycyclohexanol (V), 2-methoxy-1,3-cyclohexanediol (VI), and 3-methoxycyclohexene (VII). 1,2,3,4,10,11-Hexahydrodiphenylene oxide (VIII) yields similarly 1,2,3,4,11,12hexahydro-12-methoxydibenzodioxane (IX) and 1,2,3,4,10,11-hexahydro-10-methoxydiphenylene oxide (X). I (200 g.), 1500 cc. absolute MeOH, and 3 cc. concentrated H₂SO₄ irradiated 120 hrs. under O at 60° with ultraviolet light, neutralized with NaHCO₃, decanted, and fractionated gave 7-8 g. VII, b. 135-6°, n¹_D² 1.463, 14 g. distillate, b₁₆ 67-9° n¹_D⁰ 1.4700, which chromatographed yielded cyclohexen-3-one, n²_D⁰ 1.4798 (2,4-dinitrophenylhydrazone, m. 164-6°), and V, n¹_D⁰ 1.4612, 3-4 g. cyclic di-Me acetal of III, b₁₅ 82-4°, n²_D⁰ 1.432 [bis(2,4-dinitrophenylhydrazone) of III, m. 216-17°], and 29 g. distillate, b₁₅ 98-118°, which chromatographed gave 50-5% bis(dimethyl acetal) of III, b₁₂ 103-8° 26-30% MeO₂C(CH₄)₄CH(OMe)₂ (2,4-dinitrophenylhydra zone m. 101°), and 18-20% VI, n²_D⁰ 1.468. II (200 g.), 1500 cc. absolute MeOH, and 2.5 cc. concentrated H₂SO₄ irradiated 240 hrs. under O at 60°, and the crude product (30 g.) distilled gave 11 g. α-tetralone, b₁₂ 130° (2,4-dinitrophenylhydrazone m. 257-8°), 10 g. di-Me acetal of IV (2,4-dinitrophenylhydrazone of IV m. 148°), and 15-20% o-HOC₆H₄(CH₂)₃CO₂Me. Diphenylene oxide in absolute EtOH hydrogenated at 120°/110 atm. gave 45-50% VIII, b_0.04 51-2°, n²_D⁰ 1.545, and some perhydrodiphenylene oxide, b₂₀ 130-4°, and 0-phenylcyclohexanol, b₂0 149-53°. VIII (150 g.) in 1500 cc. absolute MeOH and 2.5 cc. concn H₂SO₄ autoxidized under O during 96 hrs. at 60°, neutralized with NH₃, concentrated, and distilled gave a crude product, b_0.3 93-6°, n²_D⁰ 1.541, which chromatographed on Al₂O₃ yielded X, n²_D⁰ 1.5533, and IX. X (1 g.), 10 cc. 2N HCl, and 5 cc. MeOH refluxed 6 hrs., neutralized with NH₃, concentrated, and chromatographed gave the 10-OH analog of X, m. 102°. IX (1 g.), 20 cc. 0.1N HCl, and 5 cc. MeOH refluxed 6 hrs., and the crude product chromatographed on Al₂O₂ yielded 0.6 g. pure IX, m. 64-8°, n⁸_D⁰ 1.542, and an unidentified material. Cumene (150 g.) autoxidized under the usual conditions during 360 hrs. gave 10-12 g. product containing 12-15% AcPh (2,4-dinitrophenylhydrazone m. 247°). Com. cumene hydroperoxide (60%) (20 g.) added dropwise to 0.5 cc. concentrated H₂SO₄ in 250 cc. absolute MeOH, cooled, neutralized with NaHCO₃, and fractionated yielded 6.7 g. cumene and 1.4 g. AcPh. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7Computed Properties of C11H14O3).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Photolactonization: a novel synthetic entry to macrolides was written by Quinkert, Gerhard;Billhardt, Uta Maria;Jakob, Harald;Fischer, Gerd;Glenneberg, Juergen;Nagler, Peter;Autze, Volker;Heim, Nana;Wacker, Manfred. And the article was included in Helvetica Chimica Acta in 1987.COA of Formula: C11H14O3 This article mentions the following:

o-Quinol acetates, hydroxyalkylated at C-6 (e.g., I), are easily accessible from simple phenols by Wessely acetoxylation (preferentially catalyzed by BF₃). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones, e.g., II. Subtle conditions were elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides was elucidated. In the experiment, the researchers used many compounds, for example, Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7COA of Formula: C11H14O3).

Methyl 4-(2-hydroxyphenyl)butanoate (cas: 93108-07-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.COA of Formula: C11H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics