Category: 85-91-6

On December 31, 2018, Farag, Mohamed A.; Elmassry, Moamen M.; El-Ahmady, Sherweit H. published an article.Application In Synthesis of Methyl N-Methylanthranilate The title of the article was The characterization of flavored hookahs aroma profile and in response to heating as analyzed via headspace solid-phase microextraction (SPME) and chemometrics. And the article contained the following:

Flavors profiling in flavored hookah tobacco is an issue of increasing scrutiny for the health sector owing to its adverse effects on humans, especially being heated to produce smoke. This study aims at tackling the components involved in the flavored hookah tobacco from a chem. and biol. point of view. Detecting individual flavor compounds, within a complex hookah tobacco matrix was accomplished using headspace solid phase microextraction (SPME). A total of 114 volatiles were identified in 13 flavored hookah tobacco products, with esters amounting for the major component up to 40%. Whereas oxygenated monoterpenes presented another major volatile class, contributing up to 23%, including (E)-anethole. Superheating flavored hookah tobacco at 190°C resulted in the release of a mixture of phenol derivatives and polycyclic aromatic compounds that are indicative of coal tar, a major component produced during hookah tobacco usage with potential health hazards. This study provides the first comprehensive volatile profile of hookah tobacco products from different origins identifying chem. components involved in flavors. It is expected to serve as informative grounds for the better understanding of hookah tobacco production and usage. The information presented is also expected to raise awareness on the health risks of hookah tobacco smoking. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Application In Synthesis of Methyl N-Methylanthranilate

The Article related to flavored hookah heating aroma profile spme chemometrics, Toxicology: Other and other aspects.Application In Synthesis of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yan, Xiao-Tong; Su, Yong-Mei; Wang, Jian published an article in 2021, the title of the article was A mini-review on the biomarkers in essential oils from peels of Citrus Reticulata blanco and their antioxidant activities.COA of Formula: C9H11NO2 And the article contains the following content:

A review. Citrus reticulata Blanco belonging to Citrus of Rutaceare is an important economical fruit plants planted all over the world. Usually, its peels were discarded as waste while they are rich in bioactive compounds like essential oils (EOs). Up to now, more than 1000 compounds have been identified in EOs from peels, flowers, leaves of Citrus species. Among these compounds, fourteen biomarkers like Limonene, γ-Terpinene, p-Cymene, Linalool, Decanal, Thymol, α-Farnesene, Me methanthranilate, Tricosane, α-Terpineol, Terpinene-4-ol, Spathulenol, α-Sinensal, and n-Hexadecanoic acid were selected from hundreds of compounds identified in essential oils from peels of Citrus reticulata Blanco by us. The antioxidant activities is an important biol. activities of these EOs, and more and more attention were focused on them these years. At the same time, the antioxidant activities of these EOs and those biomarkers were summarized in this paper. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).COA of Formula: C9H11NO2

The Article related to review citrus reticulata peel essential oil biomarker antioxidant activity, Pharmaceuticals: Reviews and other aspects.COA of Formula: C9H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mancuso, Monique; Catalfamo, Maurizio; Lagana, Pasqualina; Rappazzo, Alessandro Ciro; Raymo, Vilfredo; Zampino, Daniela; Zaccone, Renata published an article in 2019, the title of the article was Screening of antimicrobial activity of citrus essential oils against pathogenic bacteria and Candida strains.Recommanded Product: 85-91-6 And the article contains the following content:

Several studies have indicated that plants are good sources of antimicrobial agents and pharmaceuticals. The present study is focused to evaluate the antimicrobial potential of 11 citrus essential oils (EOs) and terpenes (T), against 18 bacterial pathogenic strains and 4 Candida sp. strains. Volatile compounds present in the citrus EOs were determined by a gas chromatog. anal., allowing the identification of 79 components. Results highlights that lemon, bergamot oil and terpene were effective against more than 54.5% of tested bacteria. Candida spp. strains resulted very sensitive to all terpenes and EOs. Gram neg. bacteria showed lower sensitivity than Gram pos. ones. Among Gram neg., fish pathogens were sensitive to oils, so we suggested their use as possible alternatives in aquaculture farms to prevent bacterial fish diseases. Moreover, results suggested that citrus oils could be a useful tool in the food industry to prolong the shelf-life. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Recommanded Product: 85-91-6

The Article related to citrus candida staphylococcus escherichia essential oil antimicrobial octanal myrcene, Food and Feed Chemistry: Other and other aspects.Recommanded Product: 85-91-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 31, 2021, Farag, Mohamed A.; Fathi, Doaa; Shamma, Samir; Shawkat, Mohamed Sherif A.; Shalabi, Sohir M.; El Seedi, Hesham R.; Afifi, Sherif M. published an article.Reference of Methyl N-Methylanthranilate The title of the article was Comparative metabolome classification of desert truffles Terfezia claveryi and Terfezia boudieri via its aroma and nutrients profile. And the article contained the following:

Desert truffles are popular ectomycorrhizal fungi valued worldwide for their nutritional and traditional health benefits. Herein, two chief desert truffles viz., Terfezia claveryi and T. boudieri were assessed for their metabolites heterogeneity in context of their volatile sensory and nutrients profile as analyzed via GC-MS. Primary metabolites accounting for nutritive indexes in T. claveryi and T. boudieri were investigated with 61 peaks belonging to sugars, sugar alcs. and amino acids. After headspace solid-phase microextraction (HS-SPME), a total of 106 volatiles were annotated belonging to alcs., ketones, aldehydes, esters, ethers and furans. The abundance of oxygenated monoterpenes as antimicrobials rationalizes for the folk use of desert truffles against trachoma. Benzyl isothiocyanate was detected as the sulfur containing volatile component in desert truffle and absent from truffles. Multivariate data analyses (MVA) revealed that 1-octen-3-ol and 3-octanone were the most significantly contributors in the discrimination of T. claveryi and T. boudieri specimens. Being more enriched in essential amino acids, T. claveryi provided a better sugar diet composition concurrent with lower sugars and higher sugar alcs. compared to T. boudieri. This study provides the first insight into desert truffles metabolites and sensory composition, and to account for its culinary and medicinal uses. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Reference of Methyl N-Methylanthranilate

The Article related to terfezia claveryi boudieri metabolome classification aroma nutrient profile, Food and Feed Chemistry: Other and other aspects.Reference of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2020, Seto, Yoshiki; Ohtake, Hiroto; Sato, Hideyuki; Onoue, Satomi published an article.Application of 85-91-6 The title of the article was Phototoxic risk assessment of dermally-applied chemicals with structural variety based on photoreactivity and skin deposition. And the article contained the following:

This study aimed to verify the feasibility of the screening system for phototoxic risk assessment on dermally-applied chems. with wide structural diversity, as a first attempt. Photochem. properties of test chems., 2-acetonaphthalene, 4′-methylbenzylidene camphor, 6-methylcoumarin, Me N-methylanthranilate, and sulisobenzone, were evaluated in terms of UV absorption and reactive oxygen species (ROS) generation, and PK profiles of the test chems. in rat skin were characterized after dermal co-application. All test chems. showed strong UVA/B absorption with molar extinction coefficients of over 3000 M-1·cm-1, and irradiated 2-acetonaphthalene, 6-methylcoumarin, and Me N-methylanthranilate exhibited significant ROS generation. Dermally-applied 2-acetonaphthalene and 4′-methylbenzylidene camphor indicated high and long-lasting skin deposition compared with the other test chems. Based on the photochem. and PK data, 2-acetonaphthalene was predicted to have potent phototoxic risk. The predicted phototoxic risk of the test chems. by integration of obtained data was mostly consistent with their in vivo phototoxicity observed in rat skin. The screening strategy employing photochem. and PK data would have high prediction capacity and wide applicability for photosafety evaluation of chems. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Application of 85-91-6

The Article related to uv a acetonaphthalene sulisobenzone phototoxicity skin, cassette-dosing pharmacokinetics, photosafety, phototoxicity, reactive oxygen species, structural diversity, Radiation Biochemistry: Other and other aspects.Application of 85-91-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Jianwu; Hang, Yuanxin; Yan, Tingting; Liang, Jiahui; Huang, Zhiqiang; Xu, Huilan published an article in 2018, the title of the article was Qualitative analysis of flavors and fragrances added to tea by using GC-MS.Electric Literature of 85-91-6 And the article contains the following content:

A precise identification method was developed to identify the flavors and fragrances added to tea matrix artificially using gas chromatog. with mass spectrometry and gas chromatog. with quadrupole time-of-flight mass spectrometry. The proposed method was based on the corresponding “three-column retention indexes, two exact mass numbers, one mass spectrum matching degree” database of 40 kinds of common flavors and fragrances. The intraday and the interday relative standard deviation of the retention indexes were less than 0.048 and 0.093%, resp. The accuracy of exact mass was between 0.15 and 6.22 ppm. And the validation of the created database was performed by analyzing the tea samples. Thus, the proposed method is suitable for the precise identification of the flavors and fragrances added to tea matrix artificially without standard substances as a reference The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Electric Literature of 85-91-6

The Article related to flavoring fragrance additive tea gc ms, accurate mass, flavors and fragrances, retention index, standard mass spectrum, tea, Food and Feed Chemistry: Analysis and other aspects.Electric Literature of 85-91-6

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 15, 2019, Zhou, Han-Chen; Hou, Zhi-Wei; Wang, De-Xing; Ning, Jing-Ming; Wei, Shu published an article.Formula: C9H11NO2 The title of the article was Large scale preparation, stress analysis, and storage of headspace volatile condensates from Jasminum sambac flowers. And the article contained the following:

In this study, a large-scale preparation of jasmine floral volatile condensate (FVC) was conducted using fresh flowers without any extraction solvent involvement. Condensate volatile profiles were compared to those of fresh flowers for their scent characteristics and ability to withstand manufacturing and storage. The FVC possessed a typical jasmine flower scent, a similar odor polygon shape and greatly enhanced odor intensity and character odorants linalool, indole, and Me anthranilate. In late August and Sept. in Fuzhou, China, the ratio of odor activity values for indole/linalool in FVCs was close to that of fresh flowers, indicating that these were suitable local harvest times for FVC preparation Room temperature storage for 30 mo dramatically reduced the abundance of potent odorants and FVC scent intensity, while cold temperature (4 °C) storage was able to maintain FVC clarity and scent intensity. Our findings should be helpful at improving FVC quantity, quality, and storage. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Formula: C9H11NO2

The Article related to jasminum volatile, floral volatile condensates, jasminum sambac, odor activity value: spme, storage, volatile compounds, Food and Feed Chemistry: Analysis and other aspects.Formula: C9H11NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On May 31, 2021, Kostopoulou, Ioanna; Diassakou, Antonia; Kavetsou, Eleni; Kritsi, Eftichia; Zoumpoulakis, Panagiotis; Pontiki, Eleni; Hadjipavlou-Litina, Dimitra; Detsi, Anastasia published an article.Quality Control of Methyl N-Methylanthranilate The title of the article was Novel quinolinone-pyrazoline hybrids: synthesis and evaluation of antioxidant and lipoxygenase inhibitory activity. And the article contained the following:

The present project deals with the investigation of structure-activity relationship of several quinolinone-chalcone and quinolinone-pyrazoline hybrids, in an effort to discover promising antioxidant and anti-inflammatory agents. In order to accomplish this goal, four bioactive hybrid quinolinone-chalcone compounds (8a-8d) were synthesized via an aldol condensation reaction, which were then chem. modified, forming fifteen new pyrazoline analogs (9a-9o). All the synthesized analogs were in vitro evaluated in terms of their antioxidant and soybean lipoxygenase (LOX) inhibitory activity. Among all the pyrazoline derivatives, compounds 9b and 9m were found to possess the best combined activity, whereas 9b analog exhibited the most potent LOX inhibitory activity, with IC50 value 10μM. The in silico docking results revealed that the synthetic pyrazoline analog 9b showed high AutoDock Vina score (- 10.3 kcal/mol), while all the tested derivatives presented allosteric interactions with the enzyme. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Quality Control of Methyl N-Methylanthranilate

The Article related to pyrazoline quinolinone antioxidant lipoxygenase inhibitor lipid peroxidation, antioxidant activity, chalcones, lox inhibition, lipoxygenase, pyrazolines, quinolinones, Pharmacology: Structure-Activity and other aspects.Quality Control of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 1, 2019, Czyzyk, D. J.; Valhondo, M.; Deiana, L.; Tirado-Rives, J.; Jorgensen, W. L.; Anderson, K. S. published an article.Application In Synthesis of Methyl N-Methylanthranilate The title of the article was Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors. And the article contained the following:

Cryptosporidiosis is a human gastrointestinal disease caused by protozoans of the genus Cryptosporidium, which can be fatal in immunocompromised individuals. The essential enzyme, thymidylate synthase (TS), is responsible for de novo synthesis of deoxythymidine monophosphate. The TS active site is relatively conserved between Cryptosporidium and human enzymes. In previous work, we identified compound 1, (2-amino-4-oxo-4,7-dihydro-pyrrolo[2,3-d]pyrimidin-methyl-phenyl-L-glutamic acid), as a promising selective Cryptosporidium hominis TS (ChTS) inhibitor. In the present study, we explore the structure-activity relationship around 1 glutamate moiety by synthesizing and biochem. evaluating the inhibitory activity of analogs against ChTS and human TS (hTS). X-Ray crystal structures were obtained for compounds bound to both ChTS and hTS. We establish the importance of the 2-phenylacetic acid moiety methylene linker in optimally positioning compounds 23, 24, and 25 within the active site. Moreover, through the comparison of structural data for 5, 14, 15, and 23 bound in both ChTS and hTS identified that active site rigidity is a driving force in determining inhibitor selectivity. The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Application In Synthesis of Methyl N-Methylanthranilate

The Article related to structure preparation thymidylate synthase inhibitor cryptosporidiosis, antifolate, cryptosporidium hominis, sar study, thymidylate synthase, x-ray crystallography, Pharmacology: Structure-Activity and other aspects.Application In Synthesis of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qi, Heting; Ding, Shenghua; Pan, Zhaoping; Li, Xiang; Fu, Fuhua published an article in 2020, the title of the article was Characteristic volatile fingerprints and odor activity values in different citrus-tea by HS-GC-IMS and HS-SPME-GC-MS.Reference of Methyl N-Methylanthranilate And the article contains the following content:

Citrus tea is an emerging tea drink produced from tea and the pericarp of citrus, which consumers have increasingly favored due to its potential health effects and unique flavor. This study aimed to simultaneously combine the characteristic volatile fingerprints with the odor activity values (OAVs) of different citrus teas for the first time by headspace gas chromatog.-ion mobility spectrometry (HS-GC-IMS) and headspace solid-phase microextraction-gas chromatog.-mass spectrometry (HS-SPME-GC-MS). Results showed that the establishment of a citrus tea flavor fingerprint based on HS-GC-IMS data can provide an effective means for the rapid identification and traceability of different citrus varieties. Moreover, 68 volatile compounds (OAV > 1) were identified by HS-SPME-GC-MS, which reflected the contribution of aroma compounds to the characteristic flavor of samples. Amongst them, the contribution of linalool with sweet flower fragrance was the highest. Odorants such as decanal, β-lonone, β-ionone, β-myrcene and D-limonene also contributed significantly to all samples. According to principal component anal., the samples from different citrus teas were significantly separated Visualization anal. based on Pearson correlation coefficients suggested that the correlation between key compounds was clarified. A comprehensive evaluation of the aroma of citrus tea will guide citrus tea flavor quality control and mass production The experimental process involved the reaction of Methyl N-Methylanthranilate(cas: 85-91-6).Reference of Methyl N-Methylanthranilate

The Article related to odorant odor citrus tea hs gc ims spme ms, hs-gc-ims, hs-spme-gc-ms, oav, citrus-tea, orthogonal partial least squares discrimination analysis, volatile components, Food and Feed Chemistry: Analysis and other aspects.Reference of Methyl N-Methylanthranilate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics