Category: 84-61-7

Comprehensive insights into the interactions of dicyclohexyl phthalate and its metabolite to human serum albumin was written by Lv, Xiaolan;Jiang, Zheng;Zeng, Guofang;Zhao, Sujuan;Li, Na;Chen, Fengping;Huang, Xiaojian;Yao, Jia;Tuo, Xun. And the article was included in Food and Chemical Toxicology in 2021.Application In Synthesis of Dicyclohexyl phthalate This article mentions the following:

Phthalate esters (PAEs) are a type of persistent organic pollutants and have received widespread concerns due to their adverse effects on human health. Dicyclohexyl phthalate (DCHP) and its metabolite monocyclohexyl phthalate (MCHP) were selected to explore the mechanism for interaction of PAEs with human serum albumin (HSA) through mol. docking and several spectroscopic techniques. The results showed that DCHP/MCHP can spontaneously occupy site I to form a binary complex with HSA, and DCHP exhibited higher binding affinity to HSA than MCHP. At 298 K, the binding constants (K_b) of DCHP and MCHP to HSA were 24.82 x 10⁴ and 1.04 x 10⁴ M^-1, resp. Hydrogen bonds and van der Waals forces were the major driving forces in DCHP/MCHP-HSA complex. The presence of DCHP/MCHP induced the secondary structure changes in HSA, and the pi electrons of the benzene ring skeleton of DCHP/MCHP played a key role in this binding processes. Exposure of DCHP/MCHP to TM4 cells revealed that interactions between PAEs and serum albumin can affect their cytotoxicity; DCHP showed higher toxicity than MCHP. The binding affinity of PAEs with HSA may be a valuable parameter for rapid assessment of their toxicity to organisms. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Application In Synthesis of Dicyclohexyl phthalate).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of Dicyclohexyl phthalate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Role of pretreatment and evidence for the enhanced biodegradation and mineralization of low-density polyethylene films by greater waxworm was written by Kundungal, Harsha;Gangarapu, Manjari;Sarangapani, Saran;Patchaiyappan, Arunkumar;Devipriya, Suja Purushothaman. And the article was included in Environmental Technology in 2021.Recommanded Product: 84-61-7 This article mentions the following:

The present study reports the role of pretreatment for the enhanced biodegradation of low-d. polyethylene (LDPE) with Galleria mellonella (Greater waxworm). The pretreatment of the LDPE film was carried out under solar radiation. The pretreated LDPE (PTLDPE) and untreated LDPE (UTLDPE) were characterized with AFM, FTIR and ¹H NMR techniques. The qual. anal. for the biodegradation of pretreated and untreated LDPE was examined by analyzing the Excreta residue (ER) of Galleria mellonella fed with LDPE. The mineralization of the ER of waxworm fed on Waxcomb (WC), UTLDPE and PTLDPE were studied by analyzing the changes in physiochem. properties through FTIR, ¹H NMR and GC-MS techniques in addition to weight loss percentage of PTLDPE and survival rates of the tested greater waxworms. Solar pretreatment of LDPE led to increased surface roughness which favored the waxworms to feed voraciously on PTLDPE. The post degradation studies of Waxcomb (WC), PTLDPE and UTLDPE showed 92.03 ± 2.1%, 18.57 ± 1.8% and 55.8 ± 1.2% weight loss, resp. The FTIR, ¹H NMR and GC-MS results confirm that the ER of waxworm fed on WC, UTLDPE and PTLDPE showed the presence of new carbonyl and alc. groups with increase in unsaturated hydrocarbon indicating enhanced mineralization of LDPE. The efficient mineralization of PTLDPE by waxworm was observed without affecting its survivability. A plausible mechanism of LDPE degradation has also been proposed. The rapid and cost effective biodegradation of PTLDPE through waxworm paves a new and facile route for hazardous plastic waste treatment. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Recommanded Product: 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phthalates in skin wipes: Distribution, sources, and exposure via dermal absorption was written by Zhao, Anqi;Wang, Lixin;Pang, Xueying;Liu, Fang. And the article was included in Environmental Research in 2022.Product Details of 84-61-7 This article mentions the following:

Phthalates, which are widely used in industrial products, can be dermally absorbed into the human body and harm human health. In this study, we measured the levels of phthalates in skin wipes collected from 30 undergraduate volunteers. The body surfaces wiped include the forehead, forearms, hands, back, calves, and insteps. We analyzed the characteristics and possible sources of phthalates on the skin surface and used Monte Carlo simulations to estimate dermal exposure. The mean total dermal exposure was in the range of 0.129-8.25μg/(kg·day). Seven phthalates were detected, with a detection frequency of 57-100%. Phthalate levels were not significantly different between sym. locations, but differed significantly at the same sampling location. The mean dinonyl phthalate (DNP) contribution was the highest on the forehead, back, and forearm. The mean DNP and di (2-n-butoxyethyl) phthalate (DBEP) contributions on hands were the highest and second-highest, resp. The mean DBEP contribution was the highest on calf and instep. Phthalates level was the maximum on the forehead and instep. Habit and activities can lead to significant differences in phthalate concentrations on the skin surfaces of male and female students. The sum of dermal exposure on the torso, head, and feet perhaps best approximates the total body exposure. To date, information on the dermal exposure and related species of phthalates are limited; therefore, further study is needed. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Product Details of 84-61-7).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 84-61-7

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rapid analysis of 13 phthalates in textiles by Py-GC-MS method was written by Bao, Haifeng;Zhao, Hailang;Tan, Yujing. And the article was included in Yinran in 2021.Category: esters-buliding-blocks This article mentions the following:

A method for rapid determination of 13 phthalates in textiles by pyrolysis gas chromatog. mass spectrometry (Py GC-MS) was established. The optimized anal. conditions of the pyrolyzer were the initial temperature of 200 °C, heating to 350 °C at 50 °C/min, holding for 2 min. The linear correlation coefficient was R²>0.99, the detection limit was 0.08-6.17 mg/kg, the recovery was 89.2-97.1%, and the relative standard deviation was 1.2-4.4% (n = 6). The method is simple, rapid, accurate and reliable, which can meet the daily detection requirements of 13 phthalates in textiles. In the experiment, the researchers used many compounds, for example, Dicyclohexyl phthalate (cas: 84-61-7Category: esters-buliding-blocks).

Dicyclohexyl phthalate (cas: 84-61-7) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics