Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 76308-28-6, name is Ethyl 2-(trans-4-aminocyclohexyl)acetate, A new synthetic method of this compound is introduced below., Recommanded Product: 76308-28-6
Take 5.0 g (0.032 mol) of the compound ethyl 2- (4-aminocyclohexyl) acetate,Add 50ml of dichloromethane, 8.5g (2eq) of 30% sodium hydroxide solution,Added under stirring N, N- dimethylformamide chloride 6.9g (0.064mol),The reaction was stirred at 30 C for 5h.Point the plate to control, and the reaction is over. Add 50ml of water to the reaction system.Stir for 5 minutes and separate the layers, separate the organic phase, dry and spin dry to obtain 5.2 g of the compound of formula I;
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Shangyu Jing Xin Pharmaceutical Co., Ltd.; Zhejiang Jingxin Pharmaceutical Co., Ltd.; Shanghai Jingxin Bio-pharmaceutical Co., Ltd.; Zhang Min; Zheng Fei; (11 pag.)CN110317182; (2019); A;,
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