Category: 763-69-9

Interior air pollution in automotive cabins by volatile organic compounds diffusing from interior materials: I. Survey of 101 types of Japanese domestically produced cars for private use was written by Yoshida, Toshiaki;Matsunaga, Ichiro;Tomioka, Kimiko;Kumagai, Shinji. And the article was included in Indoor and Built Environment in 2006.Electric Literature of C7H14O3 The following contents are mentioned in the article:

The types and concentrations of organic compounds in the interior air of 101 different types of Japanese domestically produced private-use cars were examined All the vehicles had been registered in the summer season as new cars and were <3 years old. The airborne compounds in the cabins were collected for 24 h under static condition with the engine stopped and the windows, doors, and vents closed. A total of 275 organic compounds, including many aliphatic hydrocarbons and aromatic hydrocarbons, were identified, and 242 of them could be quantitated for each cabin. The sum of the concentrations of 241 compounds excluding formaldehyde was approx. 600 μg/m^-3 as a median, ranging 136-3968 μg/m^-3 for the tested cars. The findings demonstrated that the air in the cabin of these cars was contaminated by high concentrations of a large variety of organic compound diffusing from the interior materials. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Electric Literature of C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Electric Literature of C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1 was written by van der Vlag, Ramon;Guo, Hao;Hapko, Uladzislau;Eleftheriadis, Nikolaos;Monjas, Leticia;Dekker, Frank J.;Hirsch, Anna K. H.. And the article was included in European Journal of Medicinal Chemistry in 2019.Application of 763-69-9 The following contents are mentioned in the article:

Human 15-lipoxygenase-1 (15-LOX-1) is a mammalian lipoxygenase which plays an important regulatory role in several CNS and inflammatory lung diseases. To further explore the role of this enzyme in drug discovery, novel potent inhibitors with favorable physicochem. properties are required. In order to identify such new inhibitors, we established a combinatorial screening method based on acylhydrazone chem. This represents a novel application of combinatorial chem. focusing on the improvement of physicochem. properties, rather than on potency. This strategy allowed us to efficiently screen 44 reaction mixtures of different hydrazides and our previously reported indole aldehyde core structure, without the need for individual synthesis of all possible combinations of building blocks. Our approach afforded three new inhibitors with IC₅₀ values in the nanomolar range and improved lipophilic ligand efficiency. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Application of 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Estimation of Maximum Transdermal Flux of Nonionized Xenobiotics from Basic Physicochemical Determinants was written by Milewski, Mikolaj;Stinchcomb, Audra L.. And the article was included in Molecular Pharmaceutics in 2012.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

An ability to estimate the maximum flux of a xenobiotic across skin is desirable from the perspective of both drug delivery and toxicol. While there is an abundance of math. models describing the estimation of drug permeability coefficients, there are relatively few that focus on the maximum flux. This article reports and evaluates a simple and easy-to-use predictive model for the estimation of maximum transdermal flux of xenobiotics based on three common mol. descriptors: logarithm of octanol-water partition coefficient, mol. weight and m.p. The use of all three can be justified on the theor. basis of their influence on the solute aqueous solubility and the partitioning into the stratum corneum lipid domain. The model explains 81% of the variability in the permeation data set composed of 208 entries and can be used to obtain a quick estimate of maximum transdermal flux when exptl. data is not readily available. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Regional features of northern Italian sparkling wines, identified using solid-phase micro extraction and comprehensive two-dimensional gas chromatography coupled with time-of-flight mass spectrometry was written by Carlin, Silvia;Vrhovsek, Urska;Franceschi, Pietro;Lotti, Cesare;Bontempo, Luana;Camin, Federica;Toubiana, David;Zottele, Fabio;Toller, Giambattista;Fait, Aaron;Mattivi, Fulvio. And the article was included in Food Chemistry in 2016.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

We carried out comprehensive mapping of volatile compounds in 70 wines, from 48 wineries and 6 vintages, representative of the two main production areas for Italian sparkling wines, by HS-SPME-GCxGC-TOF-MS and multivariate anal. The final scope was to describe the metabolomics space of these wines, and to verify whether the grape cultivar signature, the pedoclimatic influence of the production area, and the complex technol. were measurable in the final product. The wine chromatograms provided a wealth of information, with 1695 compounds being found. A large number of putative markers influenced by the cultivation area was observed A subset of 196 biomarkers fully discriminated between the two types of sparkling wines investigated. Among the new compounds, safranal and α-isophorone were observed We showed how correlation-based network anal. could be used as a tool to detect the differences in compound behavior based on external/environmental influences. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The development of a high-throughput/combinatorial workflow for the study of porous polymer networks was written by Majumdar, Partha;Bahr, James;Crowley, Elizabeth;Kallam, Alekhya;Gubbins, Nathan;Schiele, Kris;Weisz, Michael;Dirk, Shawn M.;Lenhart, Joseph L.;Chisholm, Bret J.. And the article was included in International Journal of High Throughput Screening in 2012.COA of Formula: C7H14O3 The following contents are mentioned in the article:

A high-throughput workflow was developed for the study of porous polymers generated using the process of chem. induced phase separation The workflow includes automated, parallel preparation of liquid blends containing reactive, polymer network-forming precursors and a poragen, as well as a high-throughput poragen extraction process using supercritical CO₂. A structure-process-property relationship study was conducted using epoxy-amine cross-linked networks. The exptl. design involved variations in polymer network cross-link d., poragen composition, poragen level, and cure temperature A total of 216 unique compositions were prepared Changes in opacity of the blends as they cured were monitored visually. Morphol. was characterized using a scanning electron microscope on a subset of the 216 samples. The results obtained allowed for the identification of compositional variables and process variables that enabled the production of porous networks. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9COA of Formula: C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gene expression programming strategy for estimation of flash point temperature of non-electrolyte organic compounds was written by Gharagheizi, Farhad;Ilani-Kashkouli, Poorandokht;Farahani, Nasrin;Mohammadi, Amir H.. And the article was included in Fluid Phase Equilibria in 2012.Safety of Ethyl 3-ethoxypropanoate The following contents are mentioned in the article:

The accuracy and predictability of correlations and models to determine the flammability characteristics of chem. compounds are of drastic significance in various chem. industries. In the present study, the main focus is on introducing and applying the gene expression programming (GEP) math. strategy to develop a comprehensive empirical method for this purpose. This work deals with presenting an empirical correlation to predict the flash point temperature of 1471 (non-electrolyte) organic compounds from 77 different chem. families. The parameters of the correlation include the mol. weight, critical temperature, critical pressure, acentric factor, and normal b.p. of the compounds The obtained statistical parameters including root mean square of error of the results from DIPPR 801 data (8.8, 8.9, 8.9 K for training, optimization and prediction sets, resp.) demonstrate improved accuracy of the results of the presented correlation with respect to previously-proposed methods available in open literature. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Safety of Ethyl 3-ethoxypropanoate).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of Ethyl 3-ethoxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liquefaction of giant fennel (Ferula orientalis L.) in supercritical organic solvents: Effects of liquefaction parameters on product yields and character was written by Aysu, Tevfik;Kucuk, Mehmet Masuk. And the article was included in Journal of Supercritical Fluids in 2013.Synthetic Route of C7H14O3 The following contents are mentioned in the article:

Ferula orientalis L. stalks were liquefied in an autoclave in supercritical organic solvents (methanol, ethanol, 2-propanol, acetone and 2-butanol) with (NaOH, Na₂CO₃, ZnCl₂) and without catalyst at five different temperatures ranging from 240°C to 320°C. The amounts of solid (unconverted raw material), liquid (bio-oil) and gas produced, as well as the composition of the resulting liquid phase, were determined The effects of various parameters such as temperature, solvent, catalyst and ratio of catalyst on product yields were investigated. The results showed that conversion highly depends on the temperature and catalyst. The highest bio-oil yield (53.97%) was obtained using acetone with 10% zinc chloride at 300°C. The liquid products were extracted with benzene and di-Et ether. Some of selected liquid products (bio-oils) were analyzed by elemental, FT-IR and GC-MS. 126 different compounds were identified by GC-MS in the liquid products obtained in ethanol at 300°C. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Synthetic Route of C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Synthetic Route of C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Machine learning-based prediction of toxicity of organic compounds towards fathead minnow was written by Chen, Xingmei;Dang, Limin;Yang, Hai;Huang, Xianwei;Yu, Xinliang. And the article was included in RSC Advances in 2020.Product Details of 763-69-9 The following contents are mentioned in the article:

Predicting the acute toxicity of a large dataset of diverse chems. against fathead minnows (Pimephales promelas) is challenging. In this paper, 963 organic compounds with acute toxicity towards fathead minnows were split into a training set (482 compounds) and a test set (481 compounds) with an approx. ratio of 1 : 1. Only six mol. descriptors were used to establish the quant. structure-activity/toxicity relationship (QSAR/QSTR) model for 96 h pLC₅₀ through a support vector machine (SVM) along with genetic algorithm. The optimal SVM model (R² = 0.756) was verified using both internal (leave-one-out cross-validation) and external validations. The validation results (q_int² = 0.699 and q_ext² = 0.744) were satisfactory in predicting acute toxicity in fathead minnows compared with other models reported in the literature, although our SVM model has only six mol. descriptors and a large data set for the test set consisting of 481 compounds This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Product Details of 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Discovery of a Potent and Selective Inhibitor of Cyclin-Dependent Kinase 4/6 was written by Toogood, Peter L.;Harvey, Patricia J.;Repine, Joseph T.;Sheehan, Derek J.;VanderWel, Scott N.;Zhou, Hairong;Keller, Paul R.;McNamara, Dennis J.;Sherry, Debra;Zhu, Tong;Brodfuehrer, Joanne;Choi, Chung;Barvian, Mark R.;Fry, David W.. And the article was included in Journal of Medicinal Chemistry in 2005.Recommanded Product: 763-69-9 The following contents are mentioned in the article:

A pharmacol. approach to inhibition of cyclin-dependent kinases 4 and 6 (Cdk4/6) using highly selective small mol. inhibitors has the potential to provide novel cancer therapies for clin. use. Achieving high levels of selectivity for Cdk4/6, vs. other ATP-dependent kinases, presents a significant challenge. The pyrido[2,3-d]pyrimidin-7-one template provides an effective platform for the inhibition of a broad cross-section of kinases, including Cdks. It is now demonstrated that the modification of pyrido[2,3-d]pyrimidin-7-ones to include a 2-aminopyridine side chain at the C2-position provides inhibitors with exquisite selectivity for Cdk4/6 in vitro. This selectivity profile is recapitulated in cells where the most selective inhibitors create a G₁ block at concentrations up to 100-fold the IC₅₀ for cell proliferation. On the basis of its selectivity profile and pharmacokinetic profile, compound I (PD 0332991) was identified as a drug candidate for the treatment of cancer. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Recommanded Product: 763-69-9).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 763-69-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A novel QSPR model for prediction of lower flammability limits of organic compounds based on support vector machine was written by Pan, Yong;Jiang, Juncheng;Wang, Rui;Cao, Hongyin;Cui, Yi. And the article was included in Journal of Hazardous Materials in 2009.Synthetic Route of C7H14O3 The following contents are mentioned in the article:

A quant. structure-property relationship (QSPR) study is suggested for the prediction of lower flammability limits (LFLs) of organic compounds Various kinds of mol. descriptors were calculated to represent the mol. structures of compounds, such as topol., charge, and geometric descriptors. Genetic algorithm was employed to select optimal subset of descriptors that have significant contribution to the overall LFL property. The novel chemometrics method of support vector machine was employed to model the possible quant. relationship between these selected descriptors and LFL. The resulted model showed high prediction ability that the obtained root mean square error and average absolute error for the whole dataset were 0.069 and 0.051 volume%, resp. The results were also compared with those of previously published models. The comparison results indicate the superiority of the presented model and reveal that it can be effectively used to predict the LFL of organic compounds from the mol. structures alone. This study involved multiple reactions and reactants, such as Ethyl 3-ethoxypropanoate (cas: 763-69-9Synthetic Route of C7H14O3).

Ethyl 3-ethoxypropanoate (cas: 763-69-9) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Synthetic Route of C7H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics