Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Kim, Kun-Pyo, once mentioned the application of 762-42-5, Name is Dimethyl but-2-ynedioate, molecular formula is C6H6O4, molecular weight is 142.1094, MDL number is MFCD00008456, category is esters-buliding-blocks. Now introduce a scientific discovery about this category, Safety of Dimethyl but-2-ynedioate.
Borage Oil Enhances Lamellar Body Content and Alters Fatty Acid Composition of Epidermal Ceramides in Essential Fatty Acid-Deficient Guinea Pigs
Borage oil [BO: 40.9% linoleic acid (LNA) and 24.0% gamma-linolenic acid (GLA)] reverses disrupted epidermal lipid barrier in essential fatty acid deficiency (EFAD). We determined the effects of BO on lamellar body (LB) content and LNA and GLA incorporation into epidermal ceramide 1 (CER1) and epidermal ceramide 2 (CER2), major barrier lipids. EFAD was induced in guinea pigs by a diet of 6% hydrogenated coconut oil (HCO) for 10 weeks (group HCO) or 8 weeks followed by 6% BO for 2 weeks (group HCO + BO). LB content and LNA and GLA incorporation into CER1 were higher in group HCO + BO than in group HCO. Small but significant levels of LNA, GLA, and their C20-metabolized fatty acids [dihomo-gamma-linolenic acid (DGLA) and arachidonic acid (ARA)] were incorporated into CER2, where ARA was detected at a level lower than LNA, but DGLA incorporation exceeded that for GLA in group HCO + BO. Dietary BO enhanced LB content and differential incorporation of GLA into CER1 and DGLA into CER2.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 762-42-5, Safety of Dimethyl but-2-ynedioate.