Category: 71195-85-2

Blazejewski, Jean-Claude; Hofstraat, Johannes W.; Lequesne, Christelle; Wakselman, Claude; Wiersum, Ulfert E. published the artcile< Formation of monomeric haloaryl acrylates in the presence of hindered pyridine bases>, Quality Control of 71195-85-2, the main research area is acrylate perhalophenyl perhalopyridinyl preparation; acylation perhalophenol perhalopyridinol acryloyl chloride lutidine.

Acylation of perhalogenated phenols and pyridinols by acryloyl chloride in the presence of hindered pyridines, such as 2,6-lutidine, afforded the corresponding acrylates, which were isolated in a pure form by chromatog. on a Florisil column. This was performed without in situ polymerization of the acrylates.

Journal of Fluorine Chemistry published new progress about Acylation. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Quality Control of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Das, Anindita; Theato, Patrick published the artcile< Multifaceted Synthetic Route to Functional Polyacrylates by Transesterification of Poly(pentafluorophenyl acrylates)>, HPLC of Formula: 71195-85-2, the main research area is polyacrylate transesterification polypentafluorophenyl acrylate.

Synthesis of functional polyacrylates by 4-dimethylaminopyridine (DMAP) catalyzed trans-esterification of poly(pentafluorophenyl acrylate) (polyPFPA) is reported. High fidelity and versatility of this strategy was exemplified by near quant. conversion with diverse functional alcs. (primary, secondary as well as phenolic) featuring reactive groups like alkene, alkyne or acrylate, enabling further sequential functionalization using click chem. Co-integrating an equimolar mixture of allyl and propargyl alc. produced an orthogonally clickable copolymer by thiol-ene and 1,3-cycloaddition reaction. Base catalyzed ester exchange allowed installation of acid labile Boc-L-serine to create amino acid pendent polymer keeping both NH2- and COOH-group free, thereby providing a facile route toward zwitterionic polymers. Reaction with 2-dimethylaminoethanol conferred dual pH and CO2 responsive polymers from the same reactive precursor. The synthetic strategy was further extended to attach alcs. obtained from natural resources such as geraniol, L-lactic acid or sesamol to engineer new renewable polymers. Even a graft copolymer with very high (93%) grafting d. could be achieved utilizing PEG350-OH. The trans-esterification was found to be highly selective for primary alcs. over secondary alcs. and also to the activated PFP-ester over a normal ester such as poly(Me acrylate). Using such selectivity, fluorescently tagged polymer could be synthesized by replacing only the PFP-ester of a poly(Me acrylate-co-PFPA) with 1-pyrenemethanol. Further, PFPA was polymerized with 2.0 mol % diacrylate to produce a cross-linked gel network. The PFP-ester groups of the cross-linked gel could be quant. replaced with Boc-L-serine, which upon deprotection of the Boc group resulted in a novel zwitterionic hydrogel exhibiting pH-dependent swelling properties. Time-dependent FTIR experiment suggested fast kinetics of the reaction, making this synthetic route practically applicable for postpolymn. modification. Mechanistic investigation exposed involvement of both DMAP and the nucleophilic solvent N,N-dimethylformamide (DMF) in catalyzing the reaction. This also explains the reason as to why near quant. conversion was achieved in DMF and not in the non-nucleophilic solvent 1,4-dioxane.

Macromolecules (Washington, DC, United States) published new progress about Acrylic polymers Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, HPLC of Formula: 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Durie, Karson; Razavi, Mir Jalil; Wang, Xianqiao; Locklin, Jason published the artcile< Nanoscale Surface Creasing Induced by Post-polymerization Modification>, Computed Properties of 71195-85-2, the main research area is fluoro containing polymer brush postmodification creasing; nanoscale creasing; polymer brushes; post-polymerization modification.

Creasing in soft polymeric films is a result of substantial compressive stresses that trigger instability beyond a critical strain and have been directly related to failure mechanisms in different materials. However, it has been shown that programming these instabilities into soft materials can lead to new applications, such as particle sorting, deformable capillaries, and stimuli-responsive interfaces. In this work, we present a method for fabricating reproducible nanoscale surface instabilities using reactive microcontacting printing (μCP) on activated ester polymer brush layers of poly(pentafluorophenyl acrylate). The sizes and structures of the nanoscale creases can be modulated by varying the grafting d. of the brush substrate and pressure applied during μCP. Stress is generated in the film under confinement due to the mol. weight increase of the side chains during post-polymerization modification, which results in substantial in-plane growth in the film and leads to the observed nanoscale creases.

ACS Nano published new progress about Adhesion, physical. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Computed Properties of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molle, Edgar; Mutlu, Hatice; Theato, Patrick published the artcile< Synthesis and Post-Polymerization Modification of Poly(N-(4-Vinylphenyl)Sulfonamide)s>, Name: Perfluorophenyl acrylate, the main research area is polyvinylphenylsulfonamide post modification acrylate aza Michael reaction; free radical polymerization; post-polymerization modification; sulfonamide-based polymers; β-amino acids.

Herein, a straightforward synthesis of a novel class of polymers, i.e., poly(N-(4-vinylphenyl)sulfonamide)s, and their monomers is reported. A set of monomers with varying electron densities, fine-tuned by different substituents on the aromatic sulfonamide moiety, is polymerized by free radical polymerization featuring low molar masses (2300 ≤ Mn ≤ 3200 g mol-1) and low dispersities (1.15 ≤ Dj ≤ 1.47). Further, the post-polymerization modification of the obtained polymers via aza-Michael addition with electron-deficient alkenes is demonstrated using organic superbases as catalysts, paving the way toward the facile synthesis of novel polymeric protected β-amino acid derivatives

Macromolecular Rapid Communications published new progress about Arenesulfonamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molle, Edgar; Mutlu, Hatice; Theato, Patrick published the artcile< Synthesis and Post-Polymerization Modification of Poly(N-(4-Vinylphenyl)Sulfonamide)s>, Name: Perfluorophenyl acrylate, the main research area is polyvinylphenylsulfonamide post modification acrylate aza Michael reaction; free radical polymerization; post-polymerization modification; sulfonamide-based polymers; β-amino acids.

Herein, a straightforward synthesis of a novel class of polymers, i.e., poly(N-(4-vinylphenyl)sulfonamide)s, and their monomers is reported. A set of monomers with varying electron densities, fine-tuned by different substituents on the aromatic sulfonamide moiety, is polymerized by free radical polymerization featuring low molar masses (2300 ≤ Mn ≤ 3200 g mol-1) and low dispersities (1.15 ≤ Dj ≤ 1.47). Further, the post-polymerization modification of the obtained polymers via aza-Michael addition with electron-deficient alkenes is demonstrated using organic superbases as catalysts, paving the way toward the facile synthesis of novel polymeric protected β-amino acid derivatives

Macromolecular Rapid Communications published new progress about Arenesulfonamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Uvyn, Annemiek; De Coen, Ruben; Gruijs, Mandy; Tuk, Cees W.; De Vrieze, Jana; van Egmond, Marjolein; De Geest, Bruno G. published the artcile< Efficient Innate Immune Killing of Cancer Cells Triggered by Cell Surface Anchoring of Multivalent Antibody-Recruiting Polymers>, Category: esters-buliding-blocks, the main research area is multivalent antibody recruiting polymer cancer cytolysis macrophage phagocytosis; antibodies; cancer; immune therapy; multivalency; polymer amphiphiles.

Binding of monoclonal antibodies (mAbs) onto a cell surface triggers antibody-mediated effector killing by innate immune cells through complement activation. As an alternative to mAbs, synthetic systems that can recruit endogenous antibodies from the blood stream to a cancer cell surface could be of great relevance. Herein, we explore antibody-recruiting polymers (ARPs) as a novel class of immunotherapy. ARPs consist of a cell-binding motif linked to a polymer that contains multiple small mol. antibody-binding motifs along its backbone. As a proof of concept, we employ a lipid anchor that inserts into the phospholipid cell membrane and make use of a polymeric activated ester scaffold onto which we substitute dinitrophenol as an antibody-binding motif. We demonstrate that ARPs allow for high avidity antibody binding and drive antibody recruitment to treated cells for several days. Furthermore, we show that ARP-treated cancer cells are prone to antibody-mediated killing through phagocytosis by macrophages.

Angewandte Chemie, International Edition published new progress about Antibodies and Immunoglobulins Role: BSU (Biological Study, Unclassified), THU (Therapeutic Use), BIOL (Biological Study), USES (Uses). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Byun, Hun-Soo; Kim, Chang-Ryung; Yoon, Soon-Do published the artcile< Cloud-point measurement of binary and ternary mixtures for the P(MMA-co-PnFPA) in supercritical fluoric solvents>, Related Products of 71195-85-2, the main research area is methyl methacrylate pentafluorophenyl acrylate copolymer supercritical fluorocarbon cloud point.

In this work, the poly(Me methacrylate-co-pentafluorophenyl acrylate) [P(MMA-co-PnFPA)] copolymer by dispersion polymerization in supercritical carbon dioxide was prepared The physicochem. properties for the P(MMA-co-PnFPA) were investigated with varied mole ratios of MMA vs PnFPA (20:1, 25:1 and 30:1), and 1.0 weight%, 2.0 weight% and 4.0 weight% AIBN amounts Exptl. cloud-point data up to 453 K and 220 MPa are measured for binary and ternary mixtures of P(MMA-co-PnFPA) in supercritical CH2F2, CHF3 and CHClF2. Phase behavior of binary systems for the P(MMA-co-PnFPA) [mole ratio = 25:1, AIBN: 1.0 weight% (Mw = 173,000), 2.0 weight% (Mw = 93,600), and 4.0 weight% (Mw = 74,600)] + CH2F2 (or CHF3 and CHClF2) mixtures at temperature range from 333 K to 434 K and pressure up to 153 MPa are measured the upper critical solution temperature (UCST) type behavior with neg. slope for the P(MMA-co-PnFPA) + CH2F2, and lower critical solution temperature (LCST) type curve with pos. slope for the P(MMA-co-PnFPA) + CHF3 and P(MMA-co-PnFPA) + CHClF2 mixtures Cloud-point curves for the P(MMA-co-PnFPA) [mole ratio = 20:1 (Mw = 170,000), 25:1 (Mw = 173,000), and 30:1 (Mw = 228,000); 1.0 weight% AIBN] + supercritical (CH2F2, CHF3 and CHClF2) mixtures show a neg. slope for the P(MMA-co-PnFPA) + CH2F2, and a pos. slope for the P(MMA-co-PnFPA) + CHF3 and P(MMA-co-PnFPA) + CHClF2 mixtures at temperature to 453 K and pressure up to 160 MPa. Also, the impact of MMA (or CHClF2) on phase behavior for the P(MMA-co-PnFPA) (25:1; 1.0 weight% AIBN) + CH2F2 mixtures are measured in changes of the pressure-temperature (p, T) slope from UCST behavior to LCST behavior, and with MMA (or CHClF2) co-solvent concentrations of (0.0-28.9) weight% (or CHClF2: 0.0-97.2 weight%).

Journal of Supercritical Fluids published new progress about Cloud point. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Related Products of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jo, Hanju; Haberkorn, Niko; Pan, Jia-Ahn; Vakili, Mohammad; Nielsch, Kornelius; Theato, Patrick published the artcile< Fabrication of Chemically Tunable, Hierarchically Branched Polymeric Nanostructures by Multi-branched Anodic Aluminum Oxide Templates>, Electric Literature of 71195-85-2, the main research area is branched polymeric nanostructure multi anodic aluminum oxide template.

In this paper, a template-assisted replication method is demonstrated for the fabrication of hierarchically branched polymeric nanostructures composed of post-modifiable poly(pentafluorophenyl acrylate). Anodic aluminum oxide templates with various shapes of hierarchically branched pores are fabricated by an asym. two-step anodization process. The hierarchical polymeric nanostructures are obtained by infiltration of pentafluorophenyl acrylate with a crosslinker and photoinitiator, followed by polymerization and selective removal of the template. Furthermore, the nanostructures containing reactive pentafluorophenyl ester are modified with spiropyran amine via post-polymerization modification to fabricate UV-responsive nanostructures. This method can be readily extended to other amines and offers a generalized strategy for controlling functionality and wettability of surfaces.

Langmuir published new progress about Anodization. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Electric Literature of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Specklin, Simon; Cossy, Janine published the artcile< Chemoselective Synthesis of β-Ketophosphonates Using Lithiated α-(Trimethylsilyl)methylphosphonate>, Synthetic Route of 71195-85-2, the main research area is lithiated methylsilylmethyl phosphonate preparation coupling pentafluorophenyl ester; ketophosphonate preparation.

A highly chemoselective synthesis of β-ketophosphonates from pentafluorophenyl esters and lithiated Me α-(trimethylsilyl)methylphosphonate was developed. This mild lithiated phosphonate reagent gave functionalized β-ketophosphonates, e.g., PhC(O)CH2P(O)(OMe)2, in the presence of unactivated esters with high yields. This method was compared with the standard lithiated methylphosphonate reagent.

Journal of Organic Chemistry published new progress about Esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (pentafluorophenyl esters). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Synthetic Route of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Seo, Seok Kyoo; Lim, Jeewoo; Lee, Hyemin; Heo, Hyeonjun; Char, Kookheon published the artcile< Controlled spatial dispersion of CdSe tetrapod nanocrystals with amphiphilic block copolymer particles>, Name: Perfluorophenyl acrylate, the main research area is spatial dispersion CdSe tetrapod nanocrystal amphiphilic copolymer particle.

We report, for the first time, a nanoscale control of the spatial distribution of semiconducting tetrapod (TP) nanocrystals within block copolymer particles. Polystyrene (PS) block copolymer (BCP)/CdSe TP nanocrystal hybrid particles were prepared by the nanopptn. of TP/BCP mixtures into methanol. The BCPs consisted of short, polar terminal block bearing Me disulfide anchoring moiety which serves both to bind to CdSe TP surfaces as well as to drive self-assembly during nanopptn. into polar solvent systems. The resulting BCP/TP hybrid particles showed various spatial distribution and the number d. of TPs with respect to individual polymer particles depending on the d.p. of the block copolymer as well as the nature of the solvent in which nanopptn. was done.

Polymer published new progress about Acrylic polymers, fluorine-containing, block, diblock Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (styrene-containning). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics