Category: 71195-85-2

Shamout, Fadi; Monaco, Alessandra; Yilmaz, Gokhan; Becer, Caglar Remzi; Hartmann, Laura published the artcile< Synthesis of Brush-Like Glycopolymers with Monodisperse, Sequence-Defined Side Chains and Their Interactions with Plant and Animal Lectins>, Application In Synthesis of 71195-85-2, the main research area is glycopolymer lectin interaction; brush polymers; glycopolymers; lectins; multivalency; sequence-defined.

The synthesis of brush glycopolymers mimicking the architecture of proteoglycans is achieved by grafting sequence-defined glycooligomers derived from solid-phase polymer synthesis onto a poly(active ester) scaffold. This approach gives access to a first library of brush glycopolymers with controlled variations in the degree of branching and number of carbohydrate ligands per branch. When studying lectin binding of linear and brush glycopolymers to lectins Con A (ConA), dendritic cell-specific intercellular adhesion mol.-3-grabbing non-integrin (DC-SIGN), and mannose-binding lectin (MBL), different preferences are observed with MBL showing higher binding to linear glycopolymer and ConA and DC-SIGN favoring brush glycopolymers. This finding suggests that the architecture of polymeric glycan mimetics affects binding to lectins not only in terms of creating higher avidity but potentially also selectivity ligands.

Macromolecular Rapid Communications published new progress about Dendritic cell. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Application In Synthesis of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Xiaohui; Mutlu, Hatice; Fengler, Christian; Wilhelm, Manfred; Theato, Patrick published the artcile< Dual-faced borax mediated synthesis of self-healable hydrogels merging dynamic covalent bonding and micellization>, Quality Control of 71195-85-2, the main research area is self healing hydrogel borax thiol ene click reaction micellization; mech property.

Intrinsic self-healing hydrogels with excellent mech. properties are still difficult to achieve. Here, we presented a facile method to integrate dynamic boronate ester bonds and Pluronic F127 (PF127) micelle crosslinks into one hydrogel system via a borax catalyzed thiol-ene click reaction and borax-diol chem. The hydrogel was capable of elongating up to 340% and self-healing approx. 90% of its initial stress within 24 h. Moreover, the hydrogel could endure a compressive strain of 80% without fracture, and exhibited excellent shape recovery and fatigue resistance ability as determined by the cyclic compressive loading-unloading test at 60% strain, providing a new facile route to design multifunctional hydrogels with spontaneous self-healing ability, good stretchability and excellent compressive properties.

Polymer Chemistry published new progress about Click chemistry. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Quality Control of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

De Vrieze, Jana; Van Herck, Simon; Nuhn, Lutz; De Geest, Bruno G. published the artcile< Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent>, Formula: C9H3F5O2, the main research area is pH polymer lipid amphiphile ketal RAFT chain transfer agent; amphiphiles; degradability; ketal; lipid conjugation; reversible addition-fragmentation chain transfer.

Conjugation of small mol. drug to lipid-polymer amphiphiles is a powerful strategy to alter the pharmacokinetic profile of these mols. by promoting binding to albumin or other serum mols. Incorporation of a responsive linker between the lipid anchor and the polymer chain can be of interest to avoid indefinite binding of the conjugates to hydrophobic pockets of serum proteins or phospholipid membranes when reaching a target cell or tissue. Here, the synthesis of pH-sensitive lipid-polymer conjugates by reversible addition-fragmentation chain transfer (RAFT) polymerization using a RAFT chain transfer agent that is equipped with a pH-sensitive ketal bond between a cholesterol moiety and the trithiocarbonate RAFT chain transfer group is reported. It is demonstrated that in native form these conjugates exhibit a high affinity to albumin and cell membranes but loose this ability in response to a mild acidic trigger in aqueous medium.

Macromolecular Rapid Communications published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Formula: C9H3F5O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Asadi, H.; Khoee, S.; Deckers, R. published the artcile< Polymer-grafted superparamagnetic iron oxide nanoparticles as a potential stable system for magnetic resonance imaging and doxorubicin delivery>, Name: Perfluorophenyl acrylate, the main research area is superparamagnetic iron oxide nanoparticle doxorubicin MRI polymer grafting.

Currently, there is high interest in developing multifunctional theranostic platforms with both imaging and therapeutic functions. Herein, we report a facile approach to develop polymer-grafted superparamagnetic iron oxide nanoparticles (SPIONs) as a promising system for imaging and drug delivery. A random copolymer composed of pendant-activated ester moieties, i.e., pentafluorophenyl acrylate (PFPA) and polyethylene glycol monomethyl ether methacrylate (PEGMA), were synthesized and grafted on SPION surfaces using the click reaction. The resultant multifunctional SPIONs were characterized using FT-IR, XRD, XPS, TGA and TEM, proving the presence of polymers on their surfaces. The formed polymer-grafted SPIONs are water-dispersible, stable, and biocompatible as confirmed by a cell viability assay. Relaxivity measurements show that they have a [Formula Omitted] relativity ([Formula Omitted]) of 134.40 mM-1 S-1, which is higher than the value obtained from the com. FDA approved MRI contrast agent Ferumoxytol (85 mM-1 S-1). Furthermore, doxorubicin (DOX) was loaded onto the polymeric shell of modified SPIONs and exhibited fast drug release in response to acidic conditions (pH 5.4). These results clearly indicate that the prepared modified SPIONs have great potential to serve as a multifunctional nanosystem for T2-weighted MR imaging and therapy.

RSC Advances published new progress about Cytotoxicity. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shen, Jinghui; Feng, Shiyu; Ling, Yao; Chang, Chia-Chih; Huang, Chongyu; Wu, Xiaosong; Chen, Shuo; Liu, Jie; Wu, Yonggang; Huang, Weiguo published the artcile< Responsive Zwitterionic Polymers with Humidity and Voltage Dual-Switching for Multilevel Date Encryption and Anticounterfeiting>, Synthetic Route of 71195-85-2, the main research area is responsive zwitterionic polymer humidity voltage switching encryption anticounterfeiting.

Data encryption, protection, and anticounterfeiting are crucial in the modern information society. Though a number of technologies were developed, data security is still facing severe challenges. Herein, a fundamental new approach capable of multilevel data encryption, protection, and anticounterfeiting is developed based on the responsive zwitterionic polymers named as poly(pentafluorophenyl acrylate)-co-poly[(3-((3-acrylamidopropyl)dimethylammonio)propane-1-sulfonate)] (pPFPA-co-pADPS). Detailed studies reveal that zwitterionic polymers exhibit drastic elec. property changes to humidity variation. By reliance of this feature, highly secure touchless palm-based biometric authentication is realized; further, field-effect transistors (FETs) using zwitterionic polymers as dielecs. show nonvolatile memory behaviors with good reliability and rewrite-ability. Remarkably, not only appropriate voltages but also specific humidity range are required to safely decrypt the stored message. In addition, the memory gains the ability to destroy the stored data under counterfeiting/hacking condition, thus preventing the data from being stolen by repeated trials. Therefore, a high level of data security is realized. This work provides new insights into zwitterionic copolymer dielec. based OFETs, demonstrates the first example of double-stage data encryption and protection by OFET memory, and opens up new opportunities for data-securing by responsive materials.

Chemistry of Materials published new progress about Coded information. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Synthetic Route of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molle, Edgar; Frech, Stefan; Grueger, Tilman; Theato, Patrick published the artcile< Electrochemically-initiated polymerization of reactive monomers via 4-fluorobenzenediazonium salts>, Safety of Perfluorophenyl acrylate, the main research area is electrochem polymerization reactive monomer fluorobenzenediazonium salt.

The straightforward electrochem.-initiated radical polymerization of three reactive monomers, i.e. 2,6-difluorophenyl acrylate (DFPA), pentafluorophenyl acrylate (PFPA), and glycidyl methacrylate (GMA), using a simple com. available electrochem. setup for the generation of initiating radical species from 4-fluorobenzenediazonium tetrafluoroborate upon electrochem. cathodic reduction is reported. The use of a fluorine-labeled initiator allowed for the determination of number-average molar masses Mn of fluorine-containing polymers by 19F NMR spectroscopy in addition to size-exclusion chromatog. The obtained polymers were thereafter successfully subjected to post-polymerization modifications in order to emphasize the applicability of this polymerization method in regard to highly reactive monomers.

Polymer Chemistry published new progress about Acrylic polymers, fluorine-containing Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Safety of Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Obata, Makoto; Yamai, Kouta; Takahashi, Masaki; Ueno, Shintaro; Ogura, Hiroya; Egami, Yasuhiro published the artcile< Synthesis of an oxygen-permeable block copolymer with catechol groups and its application in polymer-ceramic pressure-sensitive paint>, Computed Properties of 71195-85-2, the main research area is oxygen permeable fluoropolymer block catechol ceramic pressure sensitive paint; trifluoroethylisobutyl methacrylate acryloyldopamine block copolymer coating thermal.

An oxygen-permeable block poly(2,2,2-trifluoroethyl-co-iso-Bu methacrylate)-b-poly (N-acryloyldopamine) (FEM-b-PDOPA), in which the PDOPA segment acts as an adhesive section to attach TiO2 nanoparticles, was successfully synthesized via RAFT polymerization followed by a post-polymerization modification with dopamine. Conjugates of FEM-b-PDOPA with TiO2 nanoparticles were prepared by mixing them in chloroform and methanol. IR and solid-state CP-MAS 13C NMR spectroscopies clearly indicated the presence of FEM on the TiO2 nanoparticles. Thermogravimetric anal. of the resulting nanoparticles indicated that FEM-b-PDOPA, rather than FEM alone, was tightly bound to the TiO2 nanoparticles, and that the weight fraction was 2.5 wt%. Polymer-ceramic pressure-sensitive paint was prepared by mixing a luminescent dye, FEM, and TiO2 treated with either FEM-b-PDOPA or native TiO2. In comparison with the coating prepared using native TiO2, the pretreatment of TiO2 with FEM-b-PDOPA effectively reduced the photodegradation of the luminescent dye without deterioration in pressure and temperature sensitivity or dynamic response performance.

Polymer published new progress about Coating materials. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Computed Properties of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Son, Hyunjoo; Jang, Yeongseon; Koo, Jaseung; Lee, Jeong-Soo; Theato, Patrick; Char, Kookheon published the artcile< Penetration and exchange kinetics of primary alkyl amines applied to reactive poly(pentafluorophenyl acrylate) thin films>, SDS of cas: 71195-85-2, the main research area is alkyl amine polypentafluorophenyl acrylate exchange kinetics.

We investigated the mechanism of primary amine-induced post-polymerization modification of active ester polymer thin films composed of pentafluorophenyl acrylate (PFPA) polymers. The most important phys. parameters in the post-polymerization modification are the mol. weight of the PFPA polymers and the aliphatic chain length of the primary amines. The effects of these two parameters on the penetration depth, as well as the exchange kinetics were systematically studied by neutron reflectivity and quartz crystal microbalance with dissipation, accompanied by the measurement of surface morphol. changes by an at.-force microscopy and optical microscopy. The spin-cast PFPA polymer thin films showed distinctive differences in the exchange kinetics, as well as the penetration depth of amines as a function of the PFPA polymer mol. weight The aliphatic chain length of primary alkyl amines markedly influenced the penetration kinetics into low-mol. weight poly(PFPA) films, whereas there was no significant penetration effect on the high-mol. weight films. The high-mol. weight of the poly(PFPA) films led to the deceleration of the dissolution of amine-functionalized polymer chains in a good solvent. The results of this study may provide a good phys. background for developing reactive poly(PFPA) thin film platforms based on simple and quant. post-modification with amine-containing mols.

Polymer Journal (Tokyo, Japan) published new progress about Diffusion. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, SDS of cas: 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bachler, Patricia R.; Forry, Kaitlyn E.; Sparks, Chelsea A.; Schulz, Michael D.; Wagener, Kenneth B.; Sumerlin, Brent S. published the artcile< Modular segmented hyperbranched copolymers>, Formula: C9H3F5O2, the main research area is RAFT polymerization hyperbranched copolymer.

Modular segmented hyperbranched polymers, amenable to facile post-polymerization functionalization, were created via two distinct approaches. Self-condensing vinyl polymerization via reversible addition-fragmentation chain transfer (RAFT) polymerization and RAFT polymerization with a divinyl comonomer were employed to create well-defined highly branched materials containing activated esters amenable to highly efficient functionalization in a modular manner.

Polymer Chemistry published new progress about Branched polymers, hyperbranched dendritic polymers Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Formula: C9H3F5O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lin, Shaojian; Huang, Xia; Guo, Ronghui; Chen, Sheng; Lan, Jianwu; Theato, Patrick published the artcile< UV-triggered CO2-responsive behavior of nanofibers and their controlled drug release properties>, Safety of Perfluorophenyl acrylate, the main research area is acrylic fluoropolymer radical polymerization post polymerization nanofiber electrospinning photocrosslinking; nanofiber controlled release drug delivery system wound dressing.

A novel nanofibrous mat featuring an UV-induced CO2-responsive behavior was fabricated via electrospinning and used as a controlled drug release system. First, a random copolymer for electrospinning, poly(N,N-diethylaminoethyl acrylamide-co-N-benzylacrylamide-co-N,N-dimethyl-N-(2-nitrobenzyl)-ethaneamine acrylamide-co-4-acryloyloxy benzophenone) [P(DEEA-co-BA-co-DMNOBA-co-ABP)], was prepared based on pentafluorophenyl esters via an “”active ester-amine”” chem. reaction. Subsequently, doxorubicin hydrochloride (DOX)-loaded P(DEEA-co-BA-co-DMNOBA-co-ABP) nanofibers were fabricated, yielding a new drug-loaded nanofibrous mat as a potential wound dressing. These DOX-loaded nanofibers can respond to UV irradiation and CO2 stimulation. Interestingly, without UV irradiation, the fabricated nanofibers cannot exhibit any responsiveness. Therefore, the majority of the DOX was steadily stored in the nanofibers, even in the presence of CO2. However, upon UV irradiation, the CO2-responsive behavior of the nanofibers was activated and the prepared nanofibers swelled slightly, resulting in the release of around 42% DOX from the nanofibers. Upon further purging with CO2, the release amount of DOX from the nanofibers could reach up to approx. 85%, followed by the morphol. transition from a nanofibrous mat to a porous hydrogel film. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about Controlled-release drug delivery systems. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Safety of Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics