Category: 707-07-3

On October 14, 2019, Grell, Yvonne; Demirel, Nemrud; Harms, Klaus; Meggers, Eric published an article.SDS of cas: 707-07-3 The title of the article was Chiral Bis(oxazoline) Ligands as C2-Symmetric Chiral Auxiliaries for the Synthesis of Enantiomerically Pure Bis-Cyclometalated Rhodium(III) Complexes. And the article contained the following:

The synthesis of enantiomerically pure bis-cyclometalated rhodium(III) complexes using chiral bis(oxazoline) ligands as C2-sym. chiral auxiliaries is described. Bis(oxazolines) are versatile chiral ligands for asym. catalysis but have not been applied to the resolution of racemic mixtures of transition-metal complexes. Due to their C2 symmetry, chiral bis(oxazolines) are particularly useful for the synthesis of nonracemic transition-metal complexes with lower symmetry, and this is demonstrated with the synthesis of an enantiomerically pure rhodium(III) complex containing two different cyclometalated ligands. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).SDS of cas: 707-07-3

The Article related to bisoxazoline chiral auxiliary enantioselective cyclometalated rhodium complex preparation, crystal structure mol chiral biscyclometalated rhodium complex, Organometallic and Organometalloidal Compounds: Group Viii – Co, Ni, Ru, Rh, Pd, Os, Ir, Pt and other aspects.SDS of cas: 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 2, 2014, Suresh, Dhanusu; Kanagaraj, Kuppusamy; Pitchumani, Kasi published an article.Safety of (Trimethoxymethyl)benzene The title of the article was Microwave promoted one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazole derivatives using Al3+-K10 clay as a heterogeneous catalyst. And the article contained the following:

An efficient, inexpensive method is developed for the one-pot synthesis of 2-aryl substituted 1,3,4-oxadiazoles and 1,2,4-oxadiazoles starting from acid hydrazides and tri-Me orthoformate under solvent-free, microwave conditions using a reusable Al3+-K10 montmorillonite clay as a heterogeneous catalyst. The novelty of the present study lies in the synthesis of oxadiazole and benzimidazole moieties in a one-pot process in high yield from easily available precursors and catalysts under mild conditions. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Safety of (Trimethoxymethyl)benzene

The Article related to aryl oxadiazole derivative microwave preparation aluminum montmorillonite clay catalyst, crystal structure ethylethyloxadiazoleylbenzoimidazole, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Safety of (Trimethoxymethyl)benzene

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kotani, Shunsuke; Sakamoto, Midori; Osakama, Kazuki; Nakajima, Makoto published an article in 2015, the title of the article was A Sterically Congested α-Cyanoamine as a Cyanating Reagent: Cyanation of Acetals and Orthoesters.Product Details of 707-07-3 And the article contains the following content:

The cyanation of acetals and ortho-esters by using a sterically congested α-cyanoamine as a cyanation reagent was investigated. The α-cyanoamine effectively facilitated cyanation in the presence of trichlorosilyl triflate to produce a variety of cyanated adducts in excellent yields. Anal. of the reaction mixture by 1H NMR spectroscopy revealed that trichlorosilyl triflate produced an oxocarbenium cation species as an intermediate. Under optimized conditions the synthesis of the target compounds was achieved using 1,1,1-trifluoromethanesulfonic acid trichlorosilyl ester as a reagent and 2-(dicyclohexylamino)acetonitrile (cyanation agent amine-cyanide) and (dimethoxymethyl)benzene (benzaldehyde acetal), (3,3-dimethoxy-1-propen-1-yl)benzene, (dimethoxymethyl)cyclohexane, 1,1′-[(phenylmethylene)bis(oxymethylene)]bis[benzene], 2-phenyl-1,3-dioxolane (cyclic acetal) as starting materials. The title compounds thus formed included α-(methoxy)benzeneacetonitrile derivatives, α-(methoxy)-1-naphthaleneacetonitrile, 2-methoxy-4-phenyl-2-butenenitrile, α-(2-hydroxyethoxy)benzeneacetonitrile. Ortho-ester reactants included (trimethoxymethyl)benzene, 1,1′,1”-[methylidynetris(oxy)]tris[ethane] and 1,1,1-triethoxypentane. Products therefrom included α,α-dimethoxybenzeneacetonitrile. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Product Details of 707-07-3

The Article related to alkoxy alkanenitrile nitrile cyanation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Product Details of 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 30, 2014, Lu, Guo-ping; Lin, Ya-mei published an article.Quality Control of (Trimethoxymethyl)benzene The title of the article was A base-induced ring-opening process of 2-substituted-1,3,4-oxadiazoles for the generation of nitriles at room temperature. And the article contained the following:

A novel base-catalyzed 1,3,4-oxadiazole fragmentation for the synthesis of nitriles at room temperature was reported. This reaction was performed under transition-metal-free conditions, and provided a new ring cleavage reaction of 1,3,4-oxadiazoles in organic synthesis. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Quality Control of (Trimethoxymethyl)benzene

The Article related to oxadiazole aryl ring opening reaction, aryl nitrile preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Nitriles, Isonitriles, and Acyl Cyanides and other aspects.Quality Control of (Trimethoxymethyl)benzene

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 9, 2020, Zhu, Zixi; Glinkerman, Christopher M.; Boger, Dale L. published an article.Recommanded Product: 707-07-3 The title of the article was Selective N1/N4 1,4-Cycloaddition of 1,2,4,5-Tetrazines Enabled by Solvent Hydrogen Bonding. And the article contained the following:

An unprecedented 1,4-cycloaddition (vs 3,6-cycloaddition) of 1,2,4,5-tetrazines is described with preformed or in situ generated aryl-conjugated enamines promoted by the solvent hydrogen bonding of hexafluoroisopropanol (HFIP) that is conducted under mild reaction conditions (0.1 M HFIP, 25°C, 12 h). The reaction constitutes a formal [4 + 2] cycloaddition across the two nitrogen atoms (N1/N4) of the 1,2,4,5-tetrazine followed by a formal retro [4 + 2] cycloaddition loss of a nitrile and aromatization to generate a 1,2,4-triazine derivative The factors that impact the remarkable change in the reaction mode, optimization of reaction parameters, the scope and simplification of its implementation through in situ enamine generation from aldehydes and ketones, the reaction scope for 3,6-bis(thiomethyl)-1,2,4,5-tetrazine, a survey of participating 1,2,4,5-tetrazines, and key mechanistic insights into this reaction are detailed. Given its simplicity and breath, the study establishes a novel method for the simple and efficient one-step synthesis of 1,2,4-triazines under mild conditions from readily accessible starting materials. Whereas alternative protic solvents (e.g., MeOH vs HFIP) provide products of the conventional 3,6-cycloaddition, the enhanced hydrogen bonding capability of HFIP uniquely results in promotion of the unprecedented formal 1,4-cycloaddition As such, the studies represent an example of not just an enhancement in the rate or efficiency of a heterocyclic azadiene cycloaddition by hydrogen bonding catalysis but also the first to alter the mode (N1/N4 vs C3/C6) of cycloaddition The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Recommanded Product: 707-07-3

The Article related to tetrazine aldehyde pyrrolidine hfip cycloaddition, ketone tetrazine pyrrolidine hfip cycloaddition, triazine preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Three Or More Hetero Atoms and other aspects.Recommanded Product: 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Yadong; Haske, Wojciech; Cai, Dengke; Barlow, Stephen; Kippelen, Bernard; Marder, Seth R. published an article in 2013, the title of the article was Efficient blue-emitting electrophosphorescent organic light-emitting diodes using 2-(3,5-di(carbazol-9-yl)phenyl)-5-phenyl-1,3,4-oxadiazole as an ambipolar host.COA of Formula: C10H14O3 And the article contains the following content:

2-(3,5-Di(carbazol-9-yl)phenyl)-5-phenyl-1,3,4-oxadiazole, 1, was synthesized from the reaction of 3,5-di(carbazol-9-yl)benzohydrazide and tri-Me orthobenzoate at 185 °C. Compound 1 exhibits a glass-transition temperature of 120 °C, a reversible reduction at a half-wave potential of -2.34 V vs. ferrocenium/ferrocene, and an adiabatic triplet energy of 2.73 eV. Organic light-emitting diodes were fabricated using: solution-processed poly[6-(9H-carbazol-9-yl)-9-(4-vinylbenzyl)-9H-3,9′-bicarbazole] as the hole-transport layer; a vacuum-deposited emissive layer composed of 1 as a host and bis[(4,6-di-fluorophenyl)pyridinato-N,C2′](picolinato-N,O)iridium or fac-tris(2-phenylpyridinato-N,C2′)iridium as blue- or green-emitting phosphorescent guest mols., resp.; and vacuum-deposited 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline or 3-([1,1′-biphenyl]-4-yl)-5-(4-(tert-butyl)phenyl)-4-phenyl-4H-1,2,4-triazole as the electron-transport layer. External quantum efficiencies of up to 21 and 25% were obtained for blue- and green-emitting devices, resp. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).COA of Formula: C10H14O3

The Article related to blue emitting pholed carbazolyl phenyl oxadiazole ambipolar host, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Spectrometers and Optical Apparatus and other aspects.COA of Formula: C10H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 25, 2018, Blumel, Marcus; Nagasawa, Shota; Blackford, Katherine; Hare, Stephanie R.; Tantillo, Dean J.; Sarpong, Richmond published an article.Formula: C10H14O3 The title of the article was Rearrangement of Hydroxylated Pinene Derivatives to Fenchone-Type Frameworks: Computational Evidence for Dynamically-Controlled Selectivity. And the article contained the following:

An acid-catalyzed Prins/semipinacol rearrangement cascade reaction of hydroxylated pinene derivatives that leads to tricyclic fenchone-type scaffolds in very high yields and diastereoselectivity has been developed. Quantum chem. anal. of the selectivity-determining step provides support for the existence of an extremely flat potential energy surface around the transition state structure. This transition state structure appears to be ambimodal, i.e., the fenchone-type tricyclic scaffolds are formed in preference to the competing formation of a bornyl (camphor-type) skeleton under dynamic control via a post-transition state bifurcation (PTSB). The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Formula: C10H14O3

The Article related to diastereoselective prins semipinacol rearrangement cascade hydroxylated pinene derivative fenchone, Terpenes and Terpenoids: Monoterpenes (C10), Including Cannabinoids, Chrysanthemic Acids, and Iridoid Aglycons and other aspects.Formula: C10H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Damavandi, Saman; Sandaroos, Reza published an article in 2013, the title of the article was Novel multicomponent synthesis of 2,9-dihydro-9-methyl-2-oxo-4-aryl-1H-pyrido[2,3-b]indole-3-carbonitrile compounds.Category: esters-buliding-blocks And the article contains the following content:

A multicomponent approach for the synthesis of 2,9-dihydro-2-oxo-4-aryl-1H-pyrido[2,3-b]indole-3-carbonitrile derivatives by a one-pot cyclocondensation reaction of substituted (triethoxymethyl)arene, 1-methyl-1H-indol-2-ol and cyanoacetamide in the presence of silica supported ionic liquid [pmim]HSO4[SiO2] (silica-supported 1-methyl-3-(triethoxysilylpropyl)imidazolium hydrogen sulfate) has been reported. The title compounds thus formed included 2,9-dihydro-9-methyl-2-oxo-4-phenyl-1H-pyrido[2,3-b]indole-3-carbonitrile (I) and related substances, such as 2,9-dihydro-9-methyl-4-(1-naphthalenyl)-2-oxo-1H-pyrido[2,3-b]indole-3-carbonitrile. The synthesis of the target compounds was achieved using ortho esters, such s (triethoxymethyl)benzene, (trimethoxymethyl)benzene, etc., as starting materials. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Category: esters-buliding-blocks

The Article related to pyridoindole preparation multicomponent reaction silica ionic liquid, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aurelio, Luigi; Volpe, Rohan; Halim, Rosliana; Scammells, Peter J.; Flynn, Bernard L. published an article in 2014, the title of the article was Synthesis of thieno-fused heterocycles through reiterative iodocyclization.Application of 707-07-3 And the article contains the following content:

Iodocyclization of ethynyl Me sulfides gives 3-iodo-2-thiomethyl heterocycles, setting up the synthesis of thieno-fused systems through a subsequent iteration of alkyne coupling and iodocyclization. This approach can also be exploited in the synthesis of polyfused thiophenes. In developing this protocol it was necessary to address issues associated with unfavorable electronic bias and redox sensitivity in some substrates. The manner in which these were addressed should prove useful elsewhere in iodocyclization chem. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Application of 707-07-3

The Article related to thiomethyl alkynyl heterocycle reiterative iodocyclization, thieno fused heterocycle synthesis, Heterocyclic Compounds (More Than One Hetero Atom): Fused-Ring Systems With Two Or More Hetero Atoms, No More Than One Hetero Atom Per Ring and other aspects.Application of 707-07-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Schroeder, Sybrin P.; Kallemeijn, Wouter W.; Debets, Marjoke F.; Hansen, Thomas; Sobala, Lukasz F.; Hakki, Zalihe; Williams, Spencer J.; Beenakker, Thomas J. M.; Aerts, Johannes M. F. G.; van der Marel, Gijsbert A.; Codee, Jeroen D. C.; Davies, Gideon J.; Overkleeft, Herman S. published an article in 2018, the title of the article was Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.COA of Formula: C10H14O3 And the article contains the following content:

N-Glycans direct protein function, stability, folding and targeting, and influence immunogenicity. While most glycosidases that process N-glycans cleave a single sugar residue at a time, enzymes from glycoside hydrolase family 99 are endo-acting enzymes that cleave within complex N-glycans. Eukaryotic Golgi endo-1,2-α-mannosidase cleaves glucose-substituted mannose within immature glucosylated high-mannose N-glycans in the secretory pathway. Certain bacteria within the human gut microbiota produce endo-1,2-α-mannanase, which cleaves related structures within fungal mannan, as part of nutrient acquisition. An unconventional mechanism of catalysis was proposed for enzymes of this family, hinted at by crystal structures of imino/azasugars complexed within the active site. Based on this mechanism, we developed the synthesis of two glycosides bearing a spiro-epoxide at C-2 as electrophilic trap, to covalently bind a mechanistically important, conserved GH99 catalytic residue. The spiro-epoxyglycosides are equipped with a fluorescent tag, and following incubation with recombinant enzyme, allow concentration, time and pH dependent visualization of the bound enzyme using gel electrophoresis. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).COA of Formula: C10H14O3

The Article related to spiroepoxyglycoside covalent label fluorescent tag endomannosidase endomannanase gel electrophoresis, gh99, activity-based probes, endomannosidase, glycosidase, inhibitors and other aspects.COA of Formula: C10H14O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics