Category: 6914-71-2

Related Products of 6914-71-2, The chemical industry reduces the impact on the environment during synthesis 6914-71-2, name is 1,1-Cyclopropanedicarboxylic acid dimethyl ester, I believe this compound will play a more active role in future production and life.

Reference Example 45 Production of [1-({[tert-butyl(dimethyl)silyl]oxy}methyl)cyclopropyl]methanol To a solution of lithium aluminum hydride (9.34 g, 246 mmol) in THF (150 ml) was dropwise added a solution of dimethylcyclopropane-1,1-dicarboxylate (25.95 g, 164.1 mmol) in THF (150 ml) under ice cooling. The solution was stirred at 0 °C for 2 hours, and to the solution were slowly added water (9.5 ml), 15 percent aqueous solution of NaOH (9.5 ml) and water (30 ml), successively. Insoluble matters were filtered off, and the filtrate was concentrated to give cyclopropane-1,1-dimethylmethanol as colorless oily substance.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1-Cyclopropanedicarboxylic acid dimethyl ester, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Takeda Chemical Industries, Ltd.; EP1591446; (2005); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 6914-71-2, name is 1,1-Cyclopropanedicarboxylic acid dimethyl ester, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6914-71-2, Application In Synthesis of 1,1-Cyclopropanedicarboxylic acid dimethyl ester

Synthesis of Cyclopropane-1,1-dicarboxylic acid methyl ester KOH (42 mg, 0.75 mmol) was added to a solution cyclopropane-1,1-dicarboxylic acid dimethyl ester (100 mg, 0.63 mmol) in methanol. The resulting mixture was stirred for 4 hours at ambient temperature then concentrated. The residue was diluted with water, acidified with conc. HCl and the product was extracted with dichloromethane. The organic layer was dried over sodium sulfate and concentrated under reduced pressure to afford 65 mg (71%) of cyclopropane-1,1-dicarboxylic acid methyl ester.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,1-Cyclopropanedicarboxylic acid dimethyl ester, and friends who are interested can also refer to it.

Reference:
Patent; FOREST LABORATORIES HOLDINGS LIMITED; US2009/239848; (2009); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

6914-71-2, name is 1,1-Cyclopropanedicarboxylic acid dimethyl ester, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Application In Synthesis of 1,1-Cyclopropanedicarboxylic acid dimethyl ester

Comparative Example 1; According to the same manner as that described in Example 3, the reaction did not proceed and (S)-tert-leucinol and dimethyl cyclopropanedicarboxylate, which are starting materials, were recovered except that lithium methoxide was not used in Example 3.

The synthetic route of 6914-71-2 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Sumitomo Chemical Company, Limited; EP1698617; (2006); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics