Category: 6642-30-4

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 6642-30-4, name is Methyl methylcarbamate, This compound has unique chemical properties. The synthetic route is as follows., Formula: C3H7NO2

EXAMPLE 10 2-SEC BUTYLPHENYL N-METHYLCARBAMATE To a mixture of methyl N-methylcarbamate (0.89 g, 0.01 mole) and 2-sec butylphenol (1.5 g, 0.01 mole) in dichloroethane (10 ml), a solution of phosphorus tribromide (2.7 g, 0.01 mole) in dichloro-ethane (6 ml) was added and the mixture was refluxed for eight hours. It was then worked up and purified as described earlier to give 2-sec butylphenyl N-methylcarbamate.

According to the analysis of related databases, 6642-30-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Council of Scientific and, Industrial Research; EP446514; (1991); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of 6642-30-4, A common heterocyclic compound, 6642-30-4, name is Methyl methylcarbamate, molecular formula is C3H7NO2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

EXAMPLE 10 2-SEC BUTYLPHENYL N-METHYLCARBAMATE To a mixture of methyl N-methylcarbamate (0.89 g, 0.01 mole) and 2-sec butylphenol (1.5 g, 0.01 mole) in dichloroethane (10 ml), a solution of phosphorus tribromide (2.7 g, 0.01 mole) in dichloro-ethane (6 ml) was added and the mixture was refluxed for eight hours. It was then worked up and purified as described earlier to give 2-sec butylphenyl N-methylcarbamate of the formula (III).

The synthetic route of 6642-30-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Council of Scientific & Industrial Research; US5066819; (1991); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 6642-30-4, name is Methyl methylcarbamate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. name: Methyl methylcarbamate

Step A 6-Cyanoindazole A solution of sodium nitrite (218 mg, 3.16 mmol) in water (1 mL) was added dropwise over 2 min to a stirred suspension of 3-amino-6-cyanoindazole (250 mg, 1.58 mmol) in water (1 mL) and acetic acid (2 mL) at 0 C. The resulting thick suspension was warmed to rt. After 16 h the mixture was cooled to 0 C. and the solids were collected by filtration, washing with cold water. The solids were suspended in 0.1 M HCl (4 mL), DME (3 mL) was added and the resulting mixture was stirred and heated to 80 C. for 1.5 h. The reaction was cooled and concentrated to 1/3 the volume. The residue was neutralised with sodium bicarbonate and extracted with ethyl acetate. The ethyl acetate layer was washed with water and brine, dried (Na2SO4) and evaporated in vacuo. The residue was purified by chromatography on silica (5:1 chloroform/ethyl acetate) to give the title compound as a yellow solid: LRMS=143.1 (M)+; 1H NMR (CDCl3) delta 7.39 (dd, J=1.1 and 8.3 Hz, 1H), 7.87 (dd, J=0.9 and 8.3 Hz, 1H), 7.94 (dd, J=0.9 and 2.1 Hz, 1H), 8.21 (d, J=0.9 Hz, 1H).

The synthetic route of Methyl methylcarbamate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Merck & Co., Inc.; US6376499; (2002); B1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics