Category: 659-70-1

Flavor components in tobacco capsules identified through non-targeted quantitative analysis was written by Lim, Hyun-Hee;Choi, Kyeong-Yun;Shin, Ho-Sang. And the article was included in Journal of Mass Spectrometry in 2022.Related Products of 659-70-1 This article mentions the following:

Tobacco flavors increase the attractiveness of a tobacco brand and ultimately promote addiction. Information about what flavor and how much flavor is in flavor capsules can provide an effective way to regulate tobacco flavor. In this study, 128 flavor chems. were identified and quantified by gas chromatog.-mass spectrometry using libraries and authentic standards Validation of the developed method was performed for interference, detection limits, calibration curves, accuracy, and precision. Menthol was the main ingredient in all capsules, and the carcinogenic pulegone was detected. Detected menthofuran, benzyl alc., geraniol, and eugenol cause toxic or severe irritation, and detected lactones can increase nicotine addiction by inhibiting nicotine metabolism in smokers. Margin of exposures for carcinogenic pulegone and non-carcinogenic menthol were well below safety thresholds, indicating a significant risk of inhalation exposure. It is desirable to prohibit the use of flavor capsules in consideration of human risk. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Related Products of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Virtual screening of functional foods and dissecting their roles in modulating gene functions to support post COVID-19 complications was written by Afroz, Sharmin;Fairuz, Shadreen;Joty, Jahanara Alam;Uddin, Nazim Md.;Rahman, Atiar Md. And the article was included in Journal of Food Biochemistry in 2021.Application In Synthesis of Isopentyl 3-methylbutanoate This article mentions the following:

COVID-19 has become the focal point since 2019 after the outbreak of coronavirus disease. Many drugs are being tested and used to treat coronavirus infections; different kinds of vaccines are also introduced as preventive measure. Alternative therapeutics are as well incorporated into the health guidelines of some countries. This research aimed to look into the underlying mechanisms of functional foods and how they may improve the long-term post COVID-19 cardiovascular, diabetic, and respiratory complications through their bioactive compounds The potentiality of nine functional foods for post COVID-19 complications was investigated through computational approaches. A total of 266 bioactive compounds of these foods were searched via extensive literature reviewing. Three highly associated targets namely troponin I interacting kinase (TNNI3K), dipeptidyl peptidase 4 (DPP-4), and transforming growth factor beta 1 (TGF-灏?) were selected for cardiovascular, diabetes, and respiratory disorders, resp., after COVID-19 infections. Best docked compounds were further analyzed by network pharmacol. tools to explore their interactions with complication-related genes (MAPK1 and HSP90AA1 for cardiovascular, PPARG and TNF-alpha for diabetes, and AKT-1 for respiratory disorders). Seventy-one suggested compounds out of one-hundred and thirty-nine (139) docked compounds in network pharmacol. recommended 169 Gene Ontol. (GO) items and 99 Kyoto Encyclopedia of Genes and Genomes signaling pathways preferably AKT signaling pathway, MAPK signaling pathway, ACE2 receptor signaling pathway, insulin signaling pathway, and PPAR signaling pathway. Among the chosen functional foods, black cumin, fenugreek, garlic, ginger, turmeric, bitter melon, and Indian pennywort were found to modulate the actions. Results demonstrate that aforesaid functional foods have attenuating roles to manage post COVID-19 complications. Practical applications : Functional foods have been approaching a greater interest due to their medicinal uses other than gastronomic pleasure. Nine functional food resources have been used in this research for their traditional and ethnopharmacol. uses, but their directive-role in modulating the genes involved in the management of post COVID-19 complications is inadequately studied and reported. Therefore, the foods types used in this research may be prioritized to be used as functional foods for ameliorating the major post COVID-19 complications through appropriate science. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Application In Synthesis of Isopentyl 3-methylbutanoate).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of Isopentyl 3-methylbutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Near-Ambient-Temperature Dehydrogenative Synthesis of the Amide Bond: Mechanistic Insight and Applications was written by Kar, Sayan;Xie, Yinjun;Zhou, Quan Quan;Diskin-Posner, Yael;Ben-David, Yehoshoa;Milstein, David. And the article was included in ACS Catalysis in 2021.Recommanded Product: Isopentyl 3-methylbutanoate This article mentions the following:

The current existing methods for the amide bond synthesis via acceptorless dehydrogenative coupling of amines and alcs. all require high reaction temperatures for effective catalysis, typically involving reflux in toluene, limiting their potential practical applications. Herein, we report a system for this reaction that proceeds under mild conditions (reflux in di-Et ether, b.p. 34.6鎺矯) using ruthenium PNNH complexes. The low-temperature activity stems from the ability of Ru-PNNH complexes to activate alc. and hemiaminals at near-ambient temperatures through the assistance of the terminal N-H proton. Mechanistic studies reveal the presence of an unexpected aldehyde-bound ruthenium species during the reaction, which is also the catalytic resting state. We further utilize the low-temperature activity to synthesize several simple amide bond-containing com. available pharmaceutical drugs from the corresponding amines and alcs. via the dehydrogenative coupling method. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Recommanded Product: Isopentyl 3-methylbutanoate).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: Isopentyl 3-methylbutanoate

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Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of commercial starter cultures on the quality characteristics of fermented fish-chili paste was written by Hua, Qian;Gao, Pei;Xu, Yanshun;Xia, Wenshui;Sun, Yingying;Jiang, Qixing. And the article was included in LWT–Food Science and Technology in 2020.Product Details of 659-70-1 This article mentions the following:

The effects of com. starter cultures on the quality characteristics of fermented fish-chili paste were investigated. Five batches of fish-chili paste were prepared with different starter cultures, namely, SBM-52 (Staphylococcus xylosus, Staphylococcus carnosus, Pediococcus pentosaceus and Pediococcus lactis), PRO-MIX5 (Staphylococcus xylosus, Lactobacillus plantarum and Lactobacillus sakei), WBX-43 (Staphylococcus xylosus and Staphylococcus carnosus), V3 (Lactobacillus plantarum), and CO (spontaneous fermentation) as the control. The results showed that all the starter cultures accelerated the growth of lactic acid bacteria and obviously reduced the Enterobacteriaceae count compared with the CO batch. SBM-52, PRO-MIX5 and V3 quickly reduced the pH, and there was no obvious difference in the protease activities among these five batches (P > 0.05). The SBM-52 batch displayed a significantly higher level of total free amino acids than the control (P < 0.05). The accumulation of organic acids was mainly due to lactic acid in all the samples. Volatile anal. indicated that more ester compounds were detected in WBX-43 compared with the other samples. E-nose anal. showed an obvious difference in the overall odor among the different samples. In conclusion, the starter cultures of WBX-43 and SBM-52 could be used for the production of high-quality fish-chili paste with better flavor. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Product Details of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aroma profiles analysis of two populations of Salvia palaestina Benth. Collected from mediterranean and irano-turanian zones in Jordan was written by Barhoumi, Lina M.;Dabaibeh, Reem N.;Al-Jaber, Hala I.;Obeidat, Safwan M.;Abaza, Ismaeil F.;Khalaf, Nooman A.;Abu-Zarga, Musa H.;Afifi, Fatma U.. And the article was included in Journal of Oleo Science in 2021.Category: esters-buliding-blocks This article mentions the following:

The volatile principles emitted from different aerial organs of two S. palaestina Benth. populations (Mediterranean (Med) and Irano-Turanian (IrT)) growing wild in Jordan were extracted by Solid Phase Micro-Extraction (SPME) and analyzed by GC/MS technique. Sesquiterpene hydrocarbons dominated stems (59.38%, 49.67%) and leaves (93.28%, 32.39%) emissions from Med and IrT zones, resp. while monoterpene hydrocarbons had the major contribution to the aroma of pre-flowering buds (78.62%, 74.96%), opened flowers (76.12%, 59.99%) and petals (69.57%, 54.28%) and were mostly represented by sabinene (in Med zone) and ociemene isomers (Z & E) in IrT zone. Multivariate anal. classified the two populations into two different clusters based on their origin and indicated the occurrence of two ecotypes of this species. Different organs from the same collection site showed emission profiles of similar chem. composition In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Category: esters-buliding-blocks).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chemical Characterization of Five Tunisian Eucalyptus Essential Oils Species was written by Elaissi, Ameur;Moumni, Sarra;Roeleveld, Kevin;Larbi Khouja, Mohamed. And the article was included in Chemistry & Biodiversity in 2020.SDS of cas: 659-70-1 This article mentions the following:

Hydrodistillation of the dried leaves of five Eucalyptus species, E. alba REINW. ex BLUME, E. citriodora HOOK., E. paniculata SM., harvested from Choucha arboreta (region of Sejnane, northwest of Tunisia), E. pimpiniana MAIDEN from Mjez Elbab arboreta (north east of Tunisia) and E. bicolor A.CUNN ex HOOK from Sidi Smail arboreta (center of Tunisia), in March 2017, afforded essential oils in yields varying from 1.3鍗?.2 to 6.0鍗?.9% according to the species. E. citriodora provided the highest mean percentage of essential oil amongst all the species. Anal. by GC (RI) and GC/MS allowed the identification of 138 components representing 84.6-98.7% of the total oil. The content of the different samples varied according to the species. The main components were citronellol, followed by 1,8-cineole, 浼?pinene, 锜?cadinol, 7-epi-浼?eudesmol, trans-pinocarveol, spathulenol, aromadendrene, 绾?cadinene and 鏈?cadinene. The principal components and the hierarchical cluster analyses separated the five leaf essential oils into three groups, each group constituted a chemotype. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1SDS of cas: 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.SDS of cas: 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of short and long term irrigation with treated wastewater on chemical composition and herbicidal activity of Eucalyptus camaldulensis Dehn. essential oils was written by Maaloul, Aya;Verdeguer Sancho, Mercedes;Oddo, Martina;Saadaoui, Ezzeddine;Jebri, Monia;Michalet, Serge;Dijoux-Franca, Mariegenevieve;Mars, Mohamed;Romdhane, Mehrez. And the article was included in Notulae Botanicae Horti Agrobotanici Cluj-Napoca in 2019.Category: esters-buliding-blocks This article mentions the following:

Treated wastewater (TWW) appears to be an opportunity for irrigation. However, it could represent a stress factor for plants, and influence their metabolism, changing their secondary metabolites and, consequently, their biol. properties. Eucalyptus camaldulensis essential oil (EO) had been reported to possess phytotoxic activity. The main objective of this work was to compare the chem. composition and herbicidal activity of E. camaldulensis EO obtained from leaves of young plants and old trees irrigated with well water (WW) and TWW. Germination tests were performed in vitro against Amaranthus hybridus, Chenopodium album, Echinochloa crus-galli and Lolium perenne. The EOs composition was analyzed by gas chromatog. and gas chromatog./mass spectrometry. A high percentage of oxygenated monoterpenes, with 1,8-cineole as main compound, was found in the EOs from leaves of young plants irrigated with both types of water. The EO from leaves of old trees irrigated with WW contained a main fraction of monoterpene hydrocarbons (45.17%) with pcymene as principal compound The highest herbicidal potential was shown by the EO from young plants irrigated with TWW. It completely inhibited A. hybridus and L. perenne germination, and nearly blocked the others at all concentrations assayed. It also showed strong phytotoxic activity on seedling length. The results suggest the possible use of TWW to irrigate Eucalyptus crops as it enhances the EOs herbicidal potential that could be used as natural herbicides. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Category: esters-buliding-blocks).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In vitro and in silico genetic toxicity screening of flavor compounds and other ingredients in tobacco products with emphasis on ENDS was written by Hung, Pei-Hsuan;Savidge, Matthew;De, Mamata;Kang, Jueichuan;Healy, Sheila M.;Valerio, Luis G. Jr.. And the article was included in Journal of Applied Toxicology in 2020.Product Details of 659-70-1 This article mentions the following:

Electronic nicotine delivery systems (ENDS) are regulated tobacco products and often contain flavor compounds Given the concern of increased use and the appeal of ENDS by young people, evaluating the potential of flavors to induce DNA damage is important for health hazard identification. In this study, alternative methods were used as prioritization tools to study the genotoxic mode of action (MoA) of 150 flavor compounds In particular, clastogen-sensitive (绾琀2AX and p53) and aneugen-sensitive (p-H3 and polyploidy) biomarkers of DNA damage in human TK6 cells were aggregated through a supervised three-pronged ensemble machine learning prediction model to prioritize chems. based on genotoxicity. In addition, in silico quant. structure-activity relationship (QSAR) models were used to predict genotoxicity and carcinogenic potential. The in vitro assay identified 25 flavors as pos. for genotoxicity: 15 clastogenic, eight aneugenic and two with a mixed MoA (clastogenic and aneugenic). Twenty-three of these 25 flavors predicted to induce DNA damage in vitro are documented in public literature to be in e-liquid or in the aerosols produced by ENDS products with youth-appealing flavors and names. QSAR models predicted 46 (31%) of 150 compounds having at least one pos. call for mutagenicity, clastogenicity or rodent carcinogenicity, 49 (33%) compounds were predicted neg. for all three endpoints, and remaining compounds had no prediction call. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Product Details of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In vitro and in silico genetic toxicity screening of flavor compounds and other ingredients in tobacco products with emphasis on ENDS was written by Hung, Pei-Hsuan;Savidge, Matthew;De, Mamata;Kang, Jueichuan;Healy, Sheila M.;Valerio, Luis G. Jr.. And the article was included in Journal of Applied Toxicology in 2020.Product Details of 659-70-1 This article mentions the following:

Electronic nicotine delivery systems (ENDS) are regulated tobacco products and often contain flavor compounds Given the concern of increased use and the appeal of ENDS by young people, evaluating the potential of flavors to induce DNA damage is important for health hazard identification. In this study, alternative methods were used as prioritization tools to study the genotoxic mode of action (MoA) of 150 flavor compounds In particular, clastogen-sensitive (纬H2AX and p53) and aneugen-sensitive (p-H3 and polyploidy) biomarkers of DNA damage in human TK6 cells were aggregated through a supervised three-pronged ensemble machine learning prediction model to prioritize chems. based on genotoxicity. In addition, in silico quant. structure-activity relationship (QSAR) models were used to predict genotoxicity and carcinogenic potential. The in vitro assay identified 25 flavors as pos. for genotoxicity: 15 clastogenic, eight aneugenic and two with a mixed MoA (clastogenic and aneugenic). Twenty-three of these 25 flavors predicted to induce DNA damage in vitro are documented in public literature to be in e-liquid or in the aerosols produced by ENDS products with youth-appealing flavors and names. QSAR models predicted 46 (31%) of 150 compounds having at least one pos. call for mutagenicity, clastogenicity or rodent carcinogenicity, 49 (33%) compounds were predicted neg. for all three endpoints, and remaining compounds had no prediction call. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Product Details of 659-70-1).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Product Details of 659-70-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Electrophysiological and Behavioral Responses of Queensland Fruit Fly Females to Fruit Odors was written by Mas, Flore;Manning, Lee-Anne;Singlet, Morgane;Butler, Ruth;Mille, Christian;Suckling, David Maxwell. And the article was included in Journal of Chemical Ecology in 2020.Name: Isopentyl 3-methylbutanoate This article mentions the following:

Females of the Queensland fruit fly (QFF), Bactrocera tryoni, are amongst the most damaging pests of horticulture in Australia and neighboring countries. Females can lay eggs into more than a hundred species of fruits and vegetables, resulting in large crop losses. Sexually mature males can be managed sustainably with traps baited with long-lasting synthetic lures, and sexually immature males and females can be attracted and killed by short-lived protein baits applied directly on surfaces, with a low success rate (< 20%). No long-lasting attractants for virgin or mated females exist. With the aim of developing a female attractant for surveillance, we collected and analyzed the odors of four ripe host fruits: orange, cherry guava, banana and feijoa. Virgin and mated female QFF were tested with gas-chromatog. coupled with electro-antennog. detection to identify electrophysiol. (EAD)-active compounds We detected 41 EAD-active compounds, with seven found common for more than one fruit. Overall, mated females responded more often and with higher intensity than virgin females. In particular, five compounds present either in cherry guava or feijoa triggered a significantly higher EAD response from mated females than from virgins. Twenty-six EAD-active compounds were selected and tested individually in a Y-tube olfactometer to measure attraction of both virgin and mated females. Behavioral responses differed significantly amongst the compounds, but not strongly between virgin and mated females. We did not find any correlation between electrophysiol. and behavioral responses. Further field testing with behaviorally-active compounds is needed for the development of a new QFF female lure. In the experiment, the researchers used many compounds, for example, Isopentyl 3-methylbutanoate (cas: 659-70-1Name: Isopentyl 3-methylbutanoate).

Isopentyl 3-methylbutanoate (cas: 659-70-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Name: Isopentyl 3-methylbutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics