Category: 623-50-7

Yu, Haiyan published the artcileComprehensive two-dimensional gas chromatography mass spectrometry-based untargeted metabolomics to clarify the dynamic variations in the volatile composition of Huangjiu of different ages, Related Products of esters-buliding-blocks, the main research area is metabolome gas chromatog mass spectrometry dynamic variation volatile; Huangjiu aging; aroma attributes; comprehensive two-dimensional gas chromatography mass spectrometry; untargeted metabolomics; volatile compounds.

Aging plays an important role in the formation of aroma characteristics of Huangjiu, a traditional Chinese alc. beverage. Comprehensive two-dimensional gas chromatog. mass spectrometry (GCxGC-qMS)-based untargeted metabolomics combined with a multivariate anal. was used to investigate the dynamic variations in the aroma profile of Huangjiu during aging process and to establish the relationship between the changing volatile metabolite profiles and the age-dependent sensory attributes. A total of 144 volatile metabolites were identified by GCxGC-qMS and 63 were selected as critical metabolites based on variable importance in projection values and p-values. Based on the results of principal component anal., orthogonal partial least-squares discriminant anal., and hierarchical clustering anal., the samples of six different ages were divided into three groups: 1Y and 3Y samples, 5Y and 8Y samples, and 10Y and 15Y samples. The partial least-squares anal. results further revealed the relationship between the aromas attributes and variations of these volatile compounds The high esters, aldehydes, and lactones contents contributed to the high intensities of the sweet and ester aroma attributes of the aged Huangjiu, while the high alcs. and Et esters contents contributed to the alc. and fruity aroma attributes of the newly brewed Huangjiu. These results improve our understanding of the chem. nature of the aroma characteristics of aged Huangjiu. Huangjiu is often labeled with its age as a measure of quality, which influences consumers’ choice. Dynamic variations in volatile compounds of Huangjiu during aging and its contribution to the aroma characteristics of Huangjiu were figured out, which will assist the industry to produce better quality aged Huangjiu for consumers.

Journal of Food Science published new progress about Alcoholic beverages. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Aiyao published the artcileSelectfluor-promoted twofold sulfination of alcohols for synthesis of sulfinic ester from diaryldisulfides, Name: Ethyl 2-hydroxyacetate, the main research area is diaryl disulfide alc Selectfluor oxidative sulfination; alkyl arylsulfinate preparation.

An oxidative two-fold sulfination of alc. with Selectfluor as an efficient oxidant was developed. This reaction proceeded smoothly achieving the unprecedented sulfination transformation of varieties of diaryldisulfides and alcs. under simple conditions, affording the corresponding sulfinic esters in excellent yields. The current reaction provided a new and convenient strategy for the preparation of sulfinic esters.

Youji Huaxue published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Name: Ethyl 2-hydroxyacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Osminski, Wynter E. G. published the artcileProbing Catalyst Function – Electronic Modulation of Chiral Polyborate Anionic Catalysts, Formula: C4H8O3, the main research area is aziridine synthesis aziridiation electronic modulation chiral polyborate catalyst.

Boroxinate complexes of VAPOL and VANOL are a chiral anionic platform that can serve as a versatile staging arena for asym. catalysis. The structural underpinning of the platform is a chiral polyborate core that covalently links together alcs. (or phenols) and vaulted biaryl ligands. The polyborate platform is assembled in situ by the substrate of the reaction, and thus a multiplex of chiral catalysts can be rapidly assembled from various alcs. (or phenols) and bis-phenol ligands for screening of catalyst activity. In the present study, variations in the steric and electronic properties of the phenol/alc. component of the boroxinate catalyst are probed to reveal their effects on the asym. induction in the catalytic asym. aziridination reaction. A Hammett study is consistent with a mechanism in which the two substrates are hydrogen-bonded to the boroxinate core in the enantiogenic step. The results of the Hammett study are supported by a computational study in which it is found that the H-O distance of the protonated imine hydrogen bonded to the anionic boroxinate core decreases with an increase in the electron releasing ability of the phenol unit incorporated into the boroxinate. The results are not consistent with a mechanism in which the boroxinate catalyst functions as a Lewis acid and activates the imine by a Lewis acid/Lewis base interaction.

Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Formula: C4H8O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Bin-Shi published the artcileRh(III)-Catalyzed three-component C-H functionalization reaction with vinylene carbonate: Late-stage C-H esterification of indole derivatives, Application In Synthesis of 623-50-7, the main research area is azaarenylindole vinylene carbonate alc rhodium tandem three component esterification; indolyl acetate preparation regioselective.

An efficient and robust Rh(III)-catalyzed three-component C-H esterification reaction of indole derivatives with vinylene carbonate to access indolyl acetates was developed. This protocol exhibited high efficiency, good yields and excellent functional group tolerance. Significantly, this method provided a powerful approach for the late-stage modification of indole-based substrates and natural alcs.

Tetrahedron Letters published new progress about Acetates Role: SPN (Synthetic Preparation), PREP (Preparation). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Application In Synthesis of 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Lei published the artcileSynthesis and antibacterial evaluation of novel 1,3,4-oxadiazole derivatives containing sulfonate/carboxylate moiety, Synthetic Route of 623-50-7, the main research area is sulfonate carboxylate oxadiazole preparation agrochem antibacterial activity; 1,3,4-oxadiazole derivatives; antibacterial activity; scanning electron microscopy; xanthomonas axonopodis pv. Citri; xanthomonas oryzae pv. oryzae.

Novel sulfonate/carboxylate functionalized 1,3,4-oxadiazole derivatives I (R1 = Me, Et, 2-fluoroethyl; R2 = Ph, 2-fluorophenyl, 4-chlorophenyl, etc.) and II [R1 = Me; R3 = Ph, 4-bromophenyl, N(CH3)2, etc.] were synthesized and evaluated for their antibacterial activities. Antibacterial activity against two phytopathogens, Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac), was assayed in vitro. The preliminary results indicated that ten compounds including I [R1 = Ph, R2 = Me (A); R1 = 4-fluorophenyl, R2 = Me (B); R1 = 4-chlorophenyl, R2 = Me (C); R1 = 4-bromophenyl, R2 = Me (D); R1 = 4-fluorophenyl, R2 = Et; R1 = 4-chlorophenyl, R2 = Et; R1 = 4-bromophenyl, R2 = Et; R1 = 4-fluorophenyl, R2 = 2-fluoroethyl; R1 = 4-chlorophenyl, R2 = 2-fluoroethyl; R1 = 4-bromophenyl, R2 = 2-fluoroethyl] had good antibacterial activity against Xoo, with EC50 values ranging from 50.1-112.5μM, which was better than those of Bismerthiazol (253.5μM) and thiadiazole copper (467.4μM). Meanwhile, compounds(A), (B), (C), (D) demonstrated good inhibitory effect against Xanthomonas axonopodis pv. citri with EC50 values around 95.8-155.2μM which were better than those of bismerthiazol (274.3μM) and thiadiazole copper (406.3μM). In addition, in vivo protection activity of compounds (B), (C) against rice bacterial leaf blight was 68.6% and 62.3%, resp., which were better than bismerthiazol (49.6%) and thiadiazole copper (42.2%). Curative activity of compounds (B), (C) against rice bacterial leaf blight was 62.3% and 56.0%, which were better than bismerthiazol (42.9%) and thiadiazole copper (36.1%). Through SEM (SEM) anal., it was observed that compound (B) caused the cell membrane of Xanthomonas oryzae pv. oryzae ruptured or deformed. The present results indicated novel derivatives of 4-Ph sulfonate Me 1,3,4-oxadiazole I might be potential antibacterial agents.

Molecules published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Synthetic Route of 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jiang, Haiwei published the artcileHydrothermal liquefaction of Cd-enriched Amaranthus hypochondriacus L. in ethanol-water co-solvent: Focus on low-N bio-oil and heavy metal/metal-like distribution, HPLC of Formula: 623-50-7, the main research area is hydrothermal liquefaction cadmium amaranthus hypochondriacus; ethanol water nitrogen bio oil heavy metal.

The high nitrogen content in bio-oil from protein-rich biomass will cause the possible pollution problems by NOX emissions during combustion. In this study, Cd-enriched Amaranthus hypochondriacus L. (AHL) was treated by hydrothermal liquefaction (HTL) in ethanol-water co-solvent aiming to reduce the nitrogen content of the bio-oil. Besides, aqueous phase recycling (APR) was applied to achieve a higher bio-oil yield. HTL in ethanol-water co-solvent with APR three times resulted in the maximum bio-oil yield (47.26%) and greatly reduced the nitrogenous compounds content of bio-oil. During the APR process, the increase of total nitrogen (TN) content in the aqueous phase indicated that organic-N in the organic phase transformed into NH+4 to the aqueous phase. Acetic acid (13.87-22.37 mg/mL) was dominated in the aqueous phase, leading to a low pH value (6.27-5.29), which could serve as the possible catalyst for the HTL process during APR that can be the reason for the higher bio-oil yield. After the HTL process, Cr, Cu, Cd and Pb remained mostly in bio-char while As was present largely in the aqueous phase. Thus, this study demonstrated that the APR for HTL process in ethanol-water co-solvent can be a hopeful method to dispose the high-protein biomass for improved bio-oil yield and quality.

Fuel published new progress about Alcohols Role: TEM (Technical or Engineered Material Use), USES (Uses). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, HPLC of Formula: 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vyviurska, Olga published the artcileEnhanced multi-stir bar sorptive extraction for wine analysis: Alteration in headspace mode, Related Products of esters-buliding-blocks, the main research area is wine multi stir bar sorptive extraction; Botrytized wines; Comprehensive two-dimensional gas chromatography; Multi-SBSE; Tokaj wine region.

Multi-stir bar sorptive extraction (multi-SBSE) represents a viable alternative for recent trends in sample preparation based on a combination of extraction techniques. In this case, increased amount of sorbent and its extended polarity range could advance quality of exptl. data obtained in foodomics or metabolomics investigations. With this in mind, it was developed multi-SBSE procedure suitable for authentication of botrytized wine produced in different countries of Tokaj wine region. A design of headspace mode of multi-SBSE was modified to provide addnl. agitation of a stir bar. An expanded profile of wine samples was obtained with the application of EG-Silicone and PDMS coated stir bars in headspace and direction immersion mode, resp. Multivariate optimization based on central composite design was selected to determine the influence of various exptl. parameters, including extraction temperature enhancing headspace extraction In our case, proper description of the optimization results required application of a third-order polynomial model, which highlighted dominant influence of salt addition for extraction in both modes. Due to a large number of extracted compounds, comprehensive two-dimensional gas chromatog. (GC x GC) was used for assessment of wine samples. Such approach allows reveleaing the presence of sulfur containing compounds, diols, ketone derivatives and methoxybenzenes linking a specific geog. origin. At the same time, the results obtained for compounds common for all the samples were processed with principal component anal. (PCA). Considerable progress for discrimination of the botrytized wines was mainly achieved with combined data from EG-Silicone and PDMS extraction

Food Research International published new progress about Acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kurkiewicz, S. published the artcileContemporary analytical techniques reveal the secret composition of a 19th century Jerusalem Balsam, Formula: C4H8O3, the main research area is vanillic acid Impatiens volatile compound.

In 1719, Antonio Menzani di Cuna from the Saint Savior monastery published an alc. extract formula made from plant and herb resins under the name Jerusalem Balsam. The Balsam gained high popularity due to its remedial benefits. At the end of the 19th century, Jerusalem Balsam produced by the hermit Johannes Treutler was found to be particularly popular. We analyzed a sample of a valuable find coming from the last decade of the 19th century, making it probably the oldest surviving Jerusalem Balsam in the world. The purpose of this work was to investigate the composition of the historical sample and to try to determine the origin of its components. This was achieved by comparing the profile of volatile compounds extracted from the balsam using HS-SPME technique with the profile characteristic for plant resins as classic ingredients of the Johannes Treutler formula. The use of two chromatog. columns of different polarity, as well as the transformation of the polar components of the sample into TMS derivatives, allowed to obtain new information on the historical composition of the Balsam. Also, it can be stated with high probability that plant resins were indeed used in the production of the Balsam as referred to in the original recipe of Johannes Treutler. We also discuss challenges in determining the original composition of the Balsam.

Pharmazie published new progress about Impatiens. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Formula: C4H8O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Picado, Alfredo published the artcileA chemical probe for dark kinase STK17B derives its potency and high selectivity through a unique P-loop conformation, Quality Control of 623-50-7, the main research area is human dark kinase STK17B probe selectivity P loop structure.

STK17B is a member of the death-associated protein kinase family and has been genetically linked to the development of diverse diseases. However, the role of STK17B in normal and disease pathol. is poorly defined. Here, we present the discovery of thieno[3,2-d] pyrimidine SGC-STK17B-1 (11s), a high-quality chem. probe for this understudied “”dark”” kinase. 11S is an ATP-competitive inhibitor that showed remarkable selectivity over other kinases including the closely related STK17A. X-ray crystallog. of 11s and related thieno[3,2-d]pyrimidines bound to STK17B revealed a unique P-loop conformation characterized by a salt bridge between R41 and the carboxylic acid of the inhibitor. Mol. dynamic simulations of STK17B revealed the flexibility of the P-loop and a wide range of R41 conformations available to the apo-protein. The isomeric thieno[2,3-d]pyrimidine SGC-STK17B-1N (19g) was identified as a neg. control compound The >100-fold lower activity of 19g on STK17B was attributed to the reduced basicity of its pyrimidine N1.

Journal of Medicinal Chemistry published new progress about Apoptosis. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Quality Control of 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Colmenar, Inmaculada published the artcileTropospheric reactivity of 2-ethoxyethanol with OH and NO3 radicals and Cl atoms. Kinetic and mechanistic study, SDS of cas: 623-50-7, the main research area is ethoxyethanol hydroxyl radical chlorine tropospheric reactivity.

Recent studies reveal that 2-ethoxyethanol (2EE) (CH3CH2OCH2CH2OH) is emitted from diesel/biodiesel blends used in vehicles. This compound has also been investigated in blends with diesel fuel for the reduction of CO emissions, hydrocarbons and particulate matter. In the work described here, rate coefficients for the reactions of OH and NO3 radicals and Cl atoms with 2EE have been determined at (298 ± 2) K and a total pressure of ∼700 torr using a relative rate method with SPME/GC-MSTOF (Solid Phase Microextraction/Gas Chromatog.-Mass Spectrometry Time of Flight Detection) and FTIR (Fourier Transform IR Spectroscopy) as detection techniques. The following rate coefficients (in cm3 mol.-1 s-1) have been obtained: (2.02 ± 0.19)× 10-10, (2.17 ± 0.11) ×10-11 and (4.80 ± 0.48) × 10-15 for Cl, ·OH and ·NO3 reactions, resp. The product formation has also been investigated. Ethylene glycol monoacetate, ethylene glycol monoformate, formaldehyde, Et glycolate and Et formate have been identified as major products for ·OH and Cl reactions. The formation of nitrated compounds has also been observed for the reactions with ·NO3 and with Cl in the presence of NO. The products are explained by a mechanism involving initial attack of the oxidant at the methylene groups followed by subsequent reactions of the resulting alkyl and alkoxy radicals. The atm. lifetimes calculated for 2EE reveal that the dominant loss process for this compound is clearly the daytime reaction with the OH radical.

Atmospheric Environment published new progress about Absorption. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, SDS of cas: 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics