Category: 623-47-2

Computed Properties of C5H6O2In 2019 ,《Regiospecific synthesis of polysubstituted furans with mono- to tricarboxylates from various sulfonium acylmethylides and acetylenic estersã€?appeared in RSC Advances. The author of the article were Dong, Jun; Du, Hongguang; Xu, Jiaxi. The article conveys some information:

Polysubstituted furans I [R1 = CO2Me, CO2Et; R2 = H, CF3, CO2Me, CO2Et; R3 = H, CO2Me, CO2Et; R4 = Me, Ph, 1-naphthyl, etc.] were prepared in moderate to good yields from sulfur ylides and acetylenic esters. The direct reactions of dimethylsulfonium acylmethylides with acetylenic esters afforded furans I through a tandem sequence of Michael addition, intramol. nucleophilic addition, 4π ring opening, intramol. Michael addition and elimination. The method was extended to synthesize furan-3-carboxylate, -2,4-dicarboxylates, and -2,3,4-tricarboxylates as well. The current method provided a direct and simple strategy in synthesis of structurally diverse polysubstituted furans with mono- to tricarboxylate groups from safe and readily available dimethylsulfonium acylmethylides and different acetylenic esters. In the experiment, the researchers used Ethyl propiolate(cas: 623-47-2Computed Properties of C5H6O2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Computed Properties of C5H6O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Luo, Xiai; Zhao, Yu; Tao, Susu; Yang, Zhong-Tao; Luo, Hui; Yang, Weiguang published their research in RSC Advances in 2021. The article was titled 《A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolinesã€?Electric Literature of C5H6O2 The article contains the following contents:

A operationally simple synthesis of (Z)-1,2-dihydro-2-iminoquinolines I (R = H, F, Cl, OMe; R1 = H, Br, Me, OMe; R2 = Me, Ph, 4-bromophenyl; R3 = n-pentyl, Ph, OEt, i-Pr, OMe, Ot-Bu; R4 = Me, n-Bu, 4-chlorophenyl, etc.) that proceeds under mild conditions is achieved by copper-catalyzed reaction of 1-(2-aminophenyl)ethan-1-ones II, sulfonyl azides R4SO2N3 and terminal ynones R3C(O)CC. In particular, the reaction goes through a base-free CuAAC/ring-opening process to obtain the Z-configured products due to hydrogen bonding. In the experiment, the researchers used many compounds, for example, Ethyl propiolate(cas: 623-47-2Electric Literature of C5H6O2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Electric Literature of C5H6O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Efficient synthesis of 1-iodoalkynes via Al2O3 mediated reaction of terminal alkynes and N-iodosuccinimideã€?was written by Yao, Ming; Zhang, Jingjing; Yang, Sen; Xiong, Hangxing; Li, Li; Liu, E.; Shi, Hong. HPLC of Formula: 623-47-2 And the article was included in RSC Advances in 2020. The article conveys some information:

Iodination of terminal alkynes using N-iodosuccinimide (NIS) in the presence of γ-Al2O3 was developed to afford 1-iodoalkynes RC≡CI [R = CH2CH2OH, Ph, 2-pyridyl, etc.] with good to excellent yields (up to 99%). This described approach featured excellent chemoselectivity, good functional group tolerance and utilization of an inexpensive catalyst. The experimental process involved the reaction of Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Phosphine-Catalyzed Remote 1,7-Addition for Synthesis of Diene Carboxylates》 was written by Feng, Jiaxu; Huang, You. Related Products of 623-47-2 And the article was included in ACS Catalysis in 2020. The article conveys some information:

A phosphine-catalyzed remote 1,7-addition of vinyl allenoates was developed, providing a series of 1,3-dienes derivatives in high yields (up to 99%) and with good chemo-, regio- and stereoselectivity. This reaction demonstrated that the introduction of vinyl in allenoates effectively extended reaction types of phosphine-catalyzed nucleophilic addition of allenoates, led to concise synthesis of diene carboxylates. Notably, the enantioselective variant of this 1,7-addition was also performed by chiral phosphine catalyst. In the part of experimental materials, we found many familiar compounds, such as Ethyl propiolate(cas: 623-47-2Related Products of 623-47-2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Related Products of 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Enantioselective Alkynylation of Unstabilized Cyclic Iminium Ions》 was written by Guan, Weiye; Santana, Samantha O.; Liao, Jennie; Henninger, Kelci; Watson, Mary P.. HPLC of Formula: 623-47-2 And the article was included in ACS Catalysis in 2020. The article conveys some information:

An enantioselective copper-catalyzed alkynylation of unstabilized cyclic iminium ions has been developed. Whereas such alkynylations typically utilize pyridinium, quinolinium, and isoquinolinium intermediates, this method enables use of cyclic iminium ions unstabilized by resonance. With the use of a Lewis acid and copper catalyst, these iminium ions are generated in situ from readily available hemiaminal Me ethers and transformed into highly enantioenriched α-alkynylated cyclic amines. A variety of terminal alkynes can be incorporated in high yields and enantiomeric excesses.Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019,Organic Letters included an article by Dai, Peng; Tan, Xin; Luo, Qian; Yu, Xiang; Zhang, Shuguang; Liu, Fang; Zhang, Wei-Hua. HPLC of Formula: 623-47-2. The article was titled 《Synthesis of 3-Acyl-isoxazoles and Δ2-Isoxazolines from Methyl Ketones, Alkynes or Alkenes, and tert-Butyl Nitrite via a Csp3-H Radical Functionalization/Cycloaddition Cascade》. The information in the text is summarized as follows:

A novel metal-free tandem Csp3-H bond functionalization of ketones and 1,3-dipolar cycloaddition was developed. An efficient approach to a variety of oxazole and isoxazoline derivatives is demonstrated using the 1,3-dipolar cycloaddition of alkynes and alkenes to nitrile oxides generated by reactions of Me ketones with tert-Bu nitrite. This new protocol provides access to a variety of isoxazolines with diverse functionalities. An isoxazole generated in this way has significant antifungal activity. In the experimental materials used by the author, we found Ethyl propiolate(cas: 623-47-2HPLC of Formula: 623-47-2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.HPLC of Formula: 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Synthesis of fused conjugated polymers containing imidazo[2,1-b]thiazole units by multicomponent one-pot polymerization》 was written by Dong, Ru; Chen, Qi; Cai, Xuediao; Zhang, Qi; Liu, Zhike. Recommanded Product: Ethyl propiolate And the article was included in Polymer Chemistry in 2020. The article conveys some information:

We herein report a facile and efficient multicomponent polymerization approach to construct fused heterocyclic polymers with imidazo[2,1-b]thiazole units in the main chain. A preliminary polymerization reaction was carried out as a model reaction with 1,4-phthalaldehyde, [6,6′-bibenzothiazole]-2,2′-diamine and 1-ethynyl-4-hexylbenzene as monomers, and different polymerization conditions, including the catalyst, catalyst amount and solvent, were optimized. Based on the optimized conditions, a series of fused heterocyclic conjugated polymers containing imidazo[2,1-b]thiazole units with high-mol. weights (Mn up to 5.7 x 104) in moderate yields (up to 54.3%) were obtained. With imidazo[2,1-b]thiazoles embedded in the main chains, the resulting polymers possess outstanding solubility, relatively good thermal stability and low energy bands. A possible mechanism was proposed for the polymerization including a 5-exo-dig cyclization and then an aromatization process. In the part of experimental materials, we found many familiar compounds, such as Ethyl propiolate(cas: 623-47-2Recommanded Product: Ethyl propiolate)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Recommanded Product: Ethyl propiolate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Dongqiu; Cheng, Fang; Tang, Yuhai; Li, Jing; Li, Yang; Jiao, Jiao; Xu, Silong published their research in Organic Letters in 2021. The article was titled 《Phosphine-Catalyzed Internal Redox [4+2] Annulation between 1,4-Enynoates and Electron-Deficient Alkenes》.SDS of cas: 623-47-2 The article contains the following contents:

Herein a phosphine-catalyzed internal redox [4+2] annulation of 1,4-enynoates with electron-deficient alkenes is described, in which the γ- and φ-C(sp3)-H of the enynoates are formally oxidized for the annulation while the alkynyl moiety is converted to an alkene. The reaction offers an efficient synthesis of highly functionalized cyclohexenes I (R1 = Ph, 4-FC6H4, 4-F3CC6H4, etc.; R2 = n-Pr, Me, Et, i-Pr) in moderate to good yields with exclusive regioselectivity and high diastereoselectivity under mild conditions.Ethyl propiolate(cas: 623-47-2SDS of cas: 623-47-2) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.SDS of cas: 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Synthesis of the GHIJKL Fragment of Gymnocin-B》 were Sakai, Takeo; Sakakibara, Hideaki; Omoto, Yumi; Tsunekawa, Marina; Hadano, Yoshinori; Kato, Shota; Mori, Yuji. And the article was published in Organic Letters in 2019. Application of 623-47-2 The author mentioned the following in the article:

The GHIJKL fragment (I) of gymnocin-B was synthesized using the oxiranyl anion strategy. The first highlight of the synthesis is the bromoketone cyclization reaction on the oxepane ring to construct the fused bisoxepane GH ring. The second key step is the introduction of the trans-4-hydroxy-3-methyloxepane J ring via addition of trimethylaluminum to a conjugated oxonium moiety, followed by diastereoselective epoxidation and regioselective reduction In the experimental materials used by the author, we found Ethyl propiolate(cas: 623-47-2Application of 623-47-2)

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Application of 623-47-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nural, Yahya; Ozdemir, Sadin; Yalcin, Mustafa Serkan; Demir, Bunyamin; Atabey, Hasan; Ece, Abdulilah; Seferoglu, Zeynel published their research in ChemistrySelect in 2021. The article was titled 《Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis-1,2,3-triazole Compounds》.Synthetic Route of C5H6O2 The article contains the following contents:

In this study, new bis-1,2,3-triazole derivatives, N,N’-(1,3-phenylene)bis(2-(4-R-1H-1,2,3-triazol-1-yl)acetamide), were synthesized by copper-catalyzed azide-alkyne cycloaddition click chem. in 84-96% yield. A wide range bioactivity screening was performed to determine DNA cleavage, antioxidant, antibacterial and antifungal activities. All of the synthesized bis-1,2,3-triazoles showed excellent DNA cleavage activity and compound I, bearing 2-bromoethyl moiety as a substituent, was almost degraded all of the plasmid DNA. Mol. docking simulations suggest that the synthesized compounds act as minor groove binders of DNA. The antioxidant activities of the bis-1,2,3-triazoles were determined based on the radical scavenging effect of the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical and iron chelating activity. The compounds exhibited effective iron chelating activity at 200 mg/L while showing a moderate ability to scavenge DPPH radical. The compounds exhibited antibacterial activity with a MIC value in the range of 4-128μg/mL. Compound II, bearing cyclohexylmethyl moiety as substituent, exhibited a broad-spectrum antimicrobial activity (both antibacterial and antifungal). Four different acid dissociation constant (pKa) values of each product were determined potentiometrically in 20% (volume/volume) DMSO-water at 25 +/= 0.1°, at an ionic background of 0.1 mol/L of NaCl using the HYPERQUAD program. In addition to this study using Ethyl propiolate, there are many other studies that have used Ethyl propiolate(cas: 623-47-2Synthetic Route of C5H6O2) was used in this study.

Ethyl propiolate(cas: 623-47-2) is a clear colorless to pale yellow liquid that is soluble in ethanol, ether and chloroform. It an important organic chemical raw material and pharmaceutical intermediate. Ethyl propargylate is obtained by oxidation of propargyl alcohol to propargylic acid followed by esterification.Synthetic Route of C5H6O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics