Category: 6217-68-1

Chen, Yunle published the artcileResponse of the Aerodyne Aerosol Mass Spectrometer to Inorganic Sulfates and Organosulfur Compounds: Applications in Field and Laboratory Measurements, COA of Formula: C6H4KNO6S, the publication is Environmental Science & Technology (2019), 53(9), 5176-5186, database is CAplus and MEDLINE.

Organosulfur compounds are important components of secondary organic aerosols (SOA). While Aerodyne high-resolution time-of-flight aerosol mass spectrometers (AMS) have been extensively used in aerosol studies, the AMS response to organosulfur compounds is not well understood. This work assessed fragmentation patterns of organosulfur and inorganic sulfate compounds in the AMS, developed a method to deconvolve total sulfates into components of inorganic and organic origins, and applied this method in laboratory and field measurements. Apportionment results from laboratory isoprene photooxidation experiments showed that with an inorganic sulfate seed, sulfate functionality of organic origins can contribute ∼7% of SOA mass at peak growth. Results from southeastern US measurements showed 4% of measured sulfate is from organosulfur compounds Methanesulfonic acid was estimated for coastal and remote marine boundary layer measurements. Application of this method was assessed for unit mass-resolution data, where it performed less well due to interferences. Apportionment results demonstrated organosulfur compounds could be a non-negligible source of sulfate fragments in AMS laboratory and field datasets. A re-evaluation of previous AMS measurements over the full range of atm. conditions using this method could provide a global estimate/constraint on the contribution of organosulfur compounds

Environmental Science & Technology published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, COA of Formula: C6H4KNO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Burkhardt, George N. published the artcileNitroarylsulfuric acids and their reduction products, Product Details of C6H4KNO6S, the publication is Journal of the Chemical Society (1929), 141-52, database is CAplus.

ClSO₃H (1.4 mols.) was added to 3.7 mols. PhNMe₂ in 500 cc. CS₂ kept below 16°; to the mixture, heated to 35°, O₂NC₆H₄OH or O₂NC₁₀H₆OH (1 mol.) was added all at once; after stirring at 35° for 1 hrs., the product was poured into dilute KOH; details for the separation of the K salts are given. K o-nitrophenyl sulfate, solubility in H₂O at 17°6”; the p-isomer has the same solubility; K 1-nitro-2-naphthyl sulfate, pale yellow needles; the 4-nitro-1-naphthyl derivative forms fine, pale yellow needles. These are all rapidly hydrolyzed by very dilute HCl at 70° and slowly at 100° by 10% Ba(OH)₂, or dilute AcOH containing AcONa. Reduction with FeSO₄ in a suspension of CaCO₃ or BaCO₃ gives the corresponding NH₂ derivatives, which give Ac and benzylidene derivatives without loss of the SO₄ group. K o-aminophenyl sulfate, gives with Br a faint violet color; the p-isomer crystallines with 1 H₂O, gives a violet color with Br and with HCl or AcOH and H derivative; the K benzylidene derivative crystallines with 0.5 H₂O. K 1-amino-2-naphthyl sulfate, crystallines with 0.5 H₂O; solubility in H₂O at 17° 1.1%; Br gives a dirty green precipitate, changing to yellow with excess of Br; FeCl₃ gives an opalescence and then a blue precipitate, which changes to brown; HCl or AcOH precipitates the H derivative, needles. p-H₂NC₅H₄SO₄H yields a diazo compound, which couples with m-C₆H₄(OH)₂, giving K dihydroxybenzeneazophenyl sulfate, orange plates with 1.5 H₂O; boiling with dilute HCl splits off the HSO₄ group; the 2-hydroxynaphthalene derivative, dark red, crystallines with 0.5 H₂O; precipitates are formed with BaCl₂, CaCl₂, HgNO₃ and MgSO₄. Results of dye tests with wool are given. The SO₄H group is removed when it is o- to the NH₄ group, but the diazo oxide results. Alk. reduction of o-O₂NC₆H₄SO₄K gives a mixture of azo and hydrazo derivatives K azobenzene 2,2′-disulfate, orange plates with 0.5 H₂O, rapidly hydrolyzed at 70° by HCl. K hydrazobenzene 2,2′-disulfate, needles; solubility in H₂O at 19° 3.2%, at 32° 5.4%; a saturated solution at 20° with concentrated HCl deposits 4,4′-diaminodiphenylene di-H 3,3′-disulfate, needles with 2.5 H₂O; the K salt crysts, with 1 H₂O; characteristic reactions with Br and FeCl₃ are given. Diacetyldihydroxybenzidine, m. 292° (decomposition); heating at 300-20° for 0.75 hr. gives the dianhydro derivative, m. 164-5°; the same compound was prepared from the sulfate.

Journal of the Chemical Society published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Product Details of C6H4KNO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bojarova, Pavla published the artcileAryl sulfamates are broad spectrum inactivators of sulfatases: Effects on sulfatases from various sources, Recommanded Product: Potassium 4-nitrophenyl sulfate, the publication is Bioorganic & Medicinal Chemistry Letters (2009), 19(2), 477-480, database is CAplus and MEDLINE.

Aryl sulfamates were originally developed as inhibitors of steroid sulfatase, and have recently been shown to be powerful inactivators of a bacterial sulfatase, PaAtsA from Pseudomonas aeruginosa. We demonstrate that a simple aryl sulfamate, 3-nitrophenyl sulfamate, can inactivate sulfatases from various sources including snail, limpet and abalone. In each case inactivation was time-dependent and active-site directed, as demonstrated by protection against inactivation by substrate. These results suggest that such easily acquired aryl sulfamates can be used as reliable biochem. reagents for the study of sulfatases from a diverse array of sources.

Bioorganic & Medicinal Chemistry Letters published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Recommanded Product: Potassium 4-nitrophenyl sulfate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Denehy, Emma published the artcileGround state structures of sulfate monoesters and sulfamates reveal similar reaction coordinates for sulfuryl and sulfamyl transfer, Synthetic Route of 6217-68-1, the publication is Chemical Communications (Cambridge, United Kingdom) (2006), 314-316, database is CAplus and MEDLINE.

Structure/reactivity and structure/structure correlations of 5 sulfate monoesters and 11 sulfamate esters determined by low temperature X-ray crystallog. reveal similar ground state deformations that suggest similar reaction coordinates for sulfuryl and sulfamyl group transfer.

Chemical Communications (Cambridge, United Kingdom) published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Synthetic Route of 6217-68-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileMetabolic fate of the ester sulfate group of potassium p- nitrophenylsulfate-S³⁵, Application In Synthesis of 6217-68-1, the publication is Biochemical Journal (1960), 154-9, database is CAplus and MEDLINE.

After intraperitoneal injection of K p-nitrophenyl sulfate-S³⁵ (I) to male and female rats, the bulk of the S³⁵ appears in the urine within 24 hrs. Up to 30% of the S³⁵ of the original dose appears in the urine as inorganic sulfate-S³⁵, most of the remainder appearing as ester sulfate-S³⁵. Chromatographic examination of the urines shows the presence of at least 10 radioactive sulfate esters in addition to I. The chromatographic pattern is very similar to that obtained with the urines of rats receiving Na₂S³⁵O₄ by intraperitoneal injection. After 48 hrs. the S³⁵ is still present in the tissues. Incorporation of S³⁵ into chondroitinsulfate of skin and cartilage and into liver taurine has been demonstrated.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Application In Synthesis of 6217-68-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Khanal, Durga D. published the artcileEnhancing the selectivity of polar hydrophilic analytes with a low concentration of barium ions in the mobile phase using geopolymers and silica supports, Category: esters-buliding-blocks, the publication is Talanta (2020), 120339, database is CAplus and MEDLINE.

Charged analytes such as organic sulfonic acids, sulfates, carboxylates, and phosphates are often analyzed by hydrophilic interaction liquid chromatog. (HILIC). In many cases, these analytes do not show any selectivity and elute near the dead time using the conventional acetonitrile-ammonium acetate buffers. In this work, we introduce a powerful selectivity enhancing technique by using a trace amount of Ba²⁺ ion in the mobile phase as a general approach for HILIC with UV-Vis detection. Silica and a newly developed material called geopolymers are used as stationary phases. Geopolymers are X-ray amorphous aluminosilicate inorganic polymers with cation exchange properties. Barium exchanged geopolymers (Ba-NM-GP) are synthesized from metakaolin based geopolymer. Thorough characterization of Ba-NM-GP is reported using SEM (SEM), energy dispersive spectroscopy (EDS), Brunauer-Emmett-Teller (BET) surface area analyzer and laser diffraction particle size distribution analyzer for the determination of their shape, size, porosity, surface area and particle size distribution resp. It is demonstrated that in the absence of Ba²⁺, baseline separations of sulfonates, carboxylates, and phosphates is not possible, whereas, in the presence of Ba²⁺ in the mobile phase, these analytes are easily separated Barium perchlorate is suggested as an additive for it is UV transparent, and it has practically an unlimited solubility in acetonitrile.

Talanta published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Suzuki, Sakaru published the artcileEnzymic transsulfation from a phenol to carbohydrates, Quality Control of 6217-68-1, the publication is Biochimica et Biophysica Acta (1957), 444-5, database is CAplus and MEDLINE.

cf. C.A. 51, 2184c. Although charoninsulfuric acid (I) (a glucan polysulfate present in the mucous gland of Charonia lampas) did not incorporate S³⁵O₄^— in the presence of an Me₂CO powder of mucous gland alone, sulfation of I occurred in the presence of this Me₂CO powder when p-nitrophenylsulfuric acid was present as sulfate donor in a suitable incubation mixture From this and other results it was concluded that S³⁵O₄^— was incorporated into carbohydrate from p-nitrophenylsulfate by enzymic transsulfation, and no incorporation took place from inorganic S³⁵O₄^—.

Biochimica et Biophysica Acta published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C19H34ClN, Quality Control of 6217-68-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatases. XV. The arylsulfatases of human serum and urine, Category: esters-buliding-blocks, the publication is Biochemical Journal (1957), 668-73, database is CAplus and MEDLINE.

cf. C.A. 51, 5895e. Human serum and urine exhibit little arylsulfatase (I) activity towards K p-acetylphenyl and p-nitrophenyl sulfates. In certain circumstances urine does show activity towards these substrates, but the activity resides in sedimentable material such as cellular debris and bacteria. Both serum and urine exhibit appreciable I activity towards nitrocatechol sulfate. The activity in urine is a feature of the urine per se and probably arises only in part from cellular debris. Two enzymes, corresponding to I A and I B of human tissues, are responsible for the bulk of the I activity of urine. Some observations on the nonenzymic catalysis by serum of the alk. hydrolysis of p-nitrophenyl sulfate are reported.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatases. IX. The arylsulfatases of mammalian livers, Related Products of esters-buliding-blocks, the publication is Biochemical Journal (1955), 29-37, database is CAplus and MEDLINE.

cf. C.A. 49, 1228a. The presence of 2 arylsulfatases in the livers of rat, ox, rabbit, and mouse has been shown. The enzymes can be distinguished by the ready solubility of one of them (“soluble”) after disruption of the mitochondria by acetone-drying, incubation in hyper- and hypo-tonic solutions, or alternate freezing and thawing. In the rat the “insoluble” enzyme is localized in the microsomes of the liver cell and the soluble enzyme is found mainly in the mitochondria. The insoluble enzyme has a high affinity for p-nitrophenyl and p-acetylphenyl sulfates, while the soluble enzyme has a low affinity for these substrates but a high activity towards nitrocatechol sulfate. The soluble enzyme of rat liver has been further separated into 2 enzymes which are comparable to sulfatases A and B of ox liver.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dodgson, K. S. published the artcileSulfatase. XI. The purification and properties of the arylsulfatase of Alcaligenes met-alcaligenes, Formula: C6H4KNO6S, the publication is Biochemical Journal (1955), 374-80, database is CAplus and MEDLINE.

cf. C.A. 49, 13305c. The arylsulfatase of A. met-alcaligenes was concentrated and partially separated from nucleic acid and from other enzymes by paper electrophoresis. The enzyme concentrate gave pH-activity and substrate concentration-activity curves which were very similar to those obtained previously with the stage B enzyme (loc. cit.). The ratio of the activities towards the 3 substrates under the resp. optimum conditions was 5.2 p-acetylphenyl (APS), 5.0 p-nitrophenyl (NPS), and 1.0 nitrocatechol (NCS) sulfates, calculated on a molar basis. When account was taken of the inhibition by excess of substrate and the true V_maximum calculated the ratio became 15.1:14.4:1.0. The Michaelis constants, K_m, for the 3 substrates were 9.0, 4.75, and 2.2 × 10^-4M, resp. The heat of activation with NPS was 11 kcal./mol. Inhibition was obtained with the following substances at 0.025M: NaHSO₃ 17%, NaCN 82, NaHSO₃ 34, BaCl₂ 100, glucose 6-sulfate 17, K Et sulfate 12, Na benzenesulfonate 22, phenylhydrazine (0.0001 M) 87, hydrazine 43, semicarbazide 21, thiosemicarbazide 33, dimedone (0.05%, weight/volume) 27, Girards’ reagent P (2.5% weight/volume) 25, NH₂OH 97. Inhibition by p-chloromercuribenzoic acid could not be reversed by cysteine or glutathione. 2,4-Dinitrofluorobenzene at 0.005M gave 100% inhibition. The curves obtained by plotting pK_m against pH have shown the presence in the enzyme of 2 different substrate-binding groups: pK 8.2 and 9.4.

Biochemical Journal published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Formula: C6H4KNO6S.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics