Category: 61675-94-3

Pedersen, Ansgar Heim published the artcileN-Quaternary compounds. Part LV. Synthetic studies of the 2,3-dihydrothiazolo[3,2-c]pyrimidinium-8-olate system, Application of Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, the main research area is thiazolopyrimidiniumolate; oxathiinopyrimidine; pyrimidine thiazolo oxathiino.

5-Hydroxy-4-pyrimidinethiones form the novel 2,3-dihydrothiazolo[3,2-c]pyrimidinium-8-olate system (I; R = H, Me, Ph) on reaction with vicinal dibromides or with 2-bromopropenoic acid. Steric or electronic effects may change the reaction path towards the formation of a 2,3-dihydro[1,4]oxathiino[5,6-d]-pyrimidine (II) or may lead to S-vinylation.

Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry published new progress about thiazolopyrimidiniumolate; oxathiinopyrimidine; pyrimidine thiazolo oxathiino. 61675-94-3 belongs to class esters-buliding-blocks, name is Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, and the molecular formula is C9H16O4, Application of Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ta-Shma, Rachel published the artcileAn autoxidation study of C2 substituted pyrimidine amino reductones, Product Details of C9H16O4, the main research area is autoxidation pyrimidine amino reductone.

Three pyrimidine derivatives I (R = Me, H, SMe) , differing from isouramil(I; R = OH) and divicine (I; R = NH2) at C2, were synthesized and their autoxidation rates measured spectrophotometrically. The autoxidation rates of all five pyrimidines were correlated with σ p + values (rho = -1.28, r2 = 0.949).

Tetrahedron published new progress about Autoxidation. 61675-94-3 belongs to class esters-buliding-blocks, name is Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, and the molecular formula is C9H16O4, Product Details of C9H16O4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Konno, Tsutomu published the artcileSynthesis and application of α-trifluoromethylated aldehydes, Formula: C9H16O4, the main research area is trifluoromethylated aldehyde preparation; nucleophilic addition stereoselective trifluoromethylated aldehyde; Pummerer rearrangement; oxidative cleavage diol stereoselective.

Two methods for the synthesis of α-trifluoromethylated aldehydes are described. One is a synthetic method via Pummerer rearrangement followed by the hydrolysis under the weakly basic condition, giving the racemic aldehyde. The other is via the oxidative cleavage of the corresponding diol under the acidic condition, affording the optically active compound for the first time. Furthermore, both aldehydes underwent the reaction with some nucleophiles in good yields.

Tetrahedron published new progress about Nucleophilic addition reaction, stereoselective. 61675-94-3 belongs to class esters-buliding-blocks, name is Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, and the molecular formula is C9H16O4, Formula: C9H16O4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Chen published the artcileOptimization of 3-phenylpyrazolo[1,5-a]pyrimidines as potent corticotropin-releasing factor-1 antagonists with adequate lipophilicity and water solubility, Application In Synthesis of 61675-94-3, the main research area is phenylpyrazolopyrimidine preparation corticotropin releasing factor 1 antagonist lipophilicity solubility.

In an effort to identify potent CRF1 antagonists with proper physicochem. properties, a series of 3-phenylpyrazolo[1,5-a]pyrimidines bearing polar groups, such as amino, hydroxyl, methoxy, sulfoxide, were designed and synthesized. Several positions of the core structure were identified, where a polar group was tolerated with slight reduction in receptor binding. NBI 30545 (I) was found to have good binding affinity and potent antagonistic activity at the human CRF1 receptor. Moreover, this compound had proper lipophilicity (log D = 2.78) and good solubility in water (>10 mg/mL), and exhibited good plasma and brain exposure when given orally.

Bioorganic & Medicinal Chemistry Letters published new progress about Homo sapiens. 61675-94-3 belongs to class esters-buliding-blocks, name is Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate, and the molecular formula is C9H16O4, Application In Synthesis of 61675-94-3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics