Category: 6149-41-3

Zhu, Jian; Zhao, Guofeng; Meng, Chao; Chen, Pengjing; Shi, Xue-Rong; Lu, Yong published an article in 2021. The article was titled 《Superb Ni-foam-structured nano-intermetallic InNi3C0.5 catalyst for hydrogenation of dimethyl oxalate to ethylene glycol》, and you may find the article in Chemical Engineering Journal (Amsterdam, Netherlands).Recommanded Product: 6149-41-3 The information in the text is summarized as follows:

A high-performance Ni-foam-structured nano-intermetallic InNi3C0.5 catalyst is developed for the gas-phase hydrogenation of di-Me oxalate (DMO) to ethylene glycol (EG). The InNi3C0.5/Ni-foam catalyst is obtainable by hydrothermal growth of NiC2O4 onto the Ni-foam, impregnation with In2O3 precursor, subsequent calcination and carburization in a syngas. Despite DMO cascade hydrogenation to MG, then to EG, and finally to EtOH, such catalyst hydrogenates DMO dexterously until to EG with a high turnover frequency of 636 h-1, because the 3Ni-In and 3Ni-C sites on InNi3C0.5(1 1 1) effectively activate DMO but hinder EG over-hydrogenation to EtOH. Favorable reaction pathway on the InNi3C0.5(1 1 1) surface predicted theor. is DMO* → CH3OCOCO* → CH3OCOCHO* → CH3OCOCHOH* → MG* → CH3OCHOCH2OH* → CHOCH2OH* → HOCHCH2OH* → EG*. Moreover, the neutral Ni-foam diminishes the formation of ethers and diols. The catalyst achieves full DMO conversion with 96-98% EG selectivity and is stable for at least 2500 h under industrial-relevant conditions, and can also hydrogenate a broad scope of carbonyl compounds to corresponding alcs. with high yields. In the experiment, the researchers used Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2012,Zhang, Ye; Zhou, Haijun; Xie, Xianmei; Chen, Xiaoping published 《Synthesis of methyl 3-hydroxypropanoate by hydroesterification of ethylene oxide over dicobalt octacarbonyl catalyst》.China Petroleum Processing and Petrochemical Technology published the findings.Recommanded Product: 6149-41-3 The information in the text is summarized as follows:

Me 3-hydroxypropanoate was synthesized via hydroseterification of ethylene oxide with CO in the presence of dicobalt octacarbonyl catalyst and methanol solvent. The catalyst exhibited high catalytic activity. The effect of reaction temperature, CO pressure, methanol dosage, catalyst dosage and reaction time on catalytic reaction was investigated. The test results revealed that this reaction was greatly affected by reaction temperature, but it was not significantly affected by the CO pressure, the methanol dosage, the catalyst dosage and the reaction time. Under the optimal conditions, the conversion of ethylene oxide was equal to 92.24%, while the selectivity and yield of Me 3-hydroxypropanoate reached 88.99% and 84.35%, resp. The results came from multiple reactions, including the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Methyl 3-hydroxypropanoateIn 2009 ,《Theoretical study on the thermolysis of methyl 3-hydroxypropanoate in m-xylene solution》 was published in Journal of Molecular Structure: THEOCHEM. The article was written by Rodriguez-Linares, Diana; Codorniu-Hernandez, Edelsys; Velez-Ortiz, Ederley; Murillo-Lopez, Juliana-Andrea; Villegas-Bolanos, Paola-Andrea; Quijano-Tobon, Jairo. The article contains the following contents:

Solvent effects on the thermolysis of Me 3-hydroxypropanoate in m-xylene were studied through the SCIPCM model (MP2/6-31G(d)) and the Multiple Min. Hypersurfaces Procedure (MMH). Important information about the kinetic and thermodn. behavior of the reaction is provided by the combination of explicit and implicit models. Quantum mech. optimizations and statistical thermodn. of MMH allow to obtain thermodn. magnitudes of the reaction in solution The optimum configurations for solute-solvent associations with the explicit addition of m-xylene mols. are provided. MMH could be used as a fast and reliable way for the prediction of a reaction in certain media and addnl. information about the solute-solvent intermol. association can be obtained. After reading the article, we found that the author used Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2005,Ooka, Hirohito; Inoue, Tsutomu; Itsuno, Shinichi; Tanaka, Masato published 《Highly active and selective palladium catalyst for hydroesterification of styrene and vinyl acetate promoted by polymeric sulfonic acids》.Chemical Communications (Cambridge, United Kingdom) published the findings.COA of Formula: C4H8O3 The information in the text is summarized as follows:

Highly efficient, selective and recyclable palladium catalyst systems for hydroesterification of styrene and vinyl acetate were realized by using [1,2-phenylenebis(methylene)]bis[bis(1,1-dimethylethyl)phosphine] as ligand and polymeric sulfonic acids of limited SO3H loadings as promoter. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3COA of Formula: C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. COA of Formula: C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2014,Nicolussi, Simon; Chicca, Andrea; Rau, Mark; Rihs, Sabine; Soeberdt, Michael; Abels, Christoph; Gertsch, Jurg published 《Correlating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: From ultrapotent to hyperpotent》.Biochemical Pharmacology (Amsterdam, Netherlands) published the findings.Category: esters-buliding-blocks The information in the text is summarized as follows:

Besides the suggested role of a putative endocannabinoid membrane transporter mediating the cellular uptake of the endocannabinoid anandamide (AEA), this process is intrinsically coupled to AEA degradation by the fatty acid amide hydrolase (FAAH). Differential blockage of each mechanism is possible using specific small-mol. inhibitors. Starting from the natural product-derived 2E,4E-dodecadiene scaffold previously shown to interact with the endocannabinoid system (ECS), a series of diverse N-alkylcarbamates were prepared with the aim of generating novel ECS modulators. While being inactive at cannabinoid receptors and monoacylglycerol lipase, these N-alkylcarbamates showed potent to ultrapotent picomolar FAAH inhibition in U937 cells. Overall, a highly significant correlation (Spearman’s rho = 0.91) was found between the inhibition of FAAH and AEA cellular uptake among 54 compounds Accordingly, in HMC-1 cells lacking FAAH expression the effect on AEA cellular uptake was dramatically reduced. Unexpectedly, 3-(4,5-dihydrothiazol-2-yl)phenyl carbamates and the 3-(1,2,3-thiadiazol-4-yl)phenyl carbamates WOBE490, WOBE491 and WOBE492 showed a potentiation of cellular AEA uptake inhibition in U937 cells, resulting in unprecedented femtomolar (hyperpotent) IC50 values. Potential methodol. issues and the role of cellular accumulation of selected probes were investigated. It is shown that albumin impacts the potency of specific N-alkylcarbamates and, more importantly, that accumulation of FAAH inhibitors can significantly increase their effect on cellular AEA uptake. Taken together, this series of N-alkylcarbamates shows a FAAH-dependent inhibition of cellular AEA uptake, which can be strongly potentiated using specific head group modifications. These findings provide a rational basis for the development of hyperpotent AEA uptake inhibitors mediated by ultrapotent FAAH inhibition. In addition to this study using Methyl 3-hydroxypropanoate, there are many other studies that have used Methyl 3-hydroxypropanoate(cas: 6149-41-3Category: esters-buliding-blocks) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2013,Schofield, Joseph; Brasseur, Denis; Bruin, Beatrice; Vassal, Thierry; Klieber, Sylvie; Arabeyre, Catherine; Bourrie, Martine; Sadoun, Freddy; Fabre, Gerard published 《Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds-synthesis and in vitro metabolism of deuterated derivatives of dronedarone》.Journal of Labelled Compounds and Radiopharmaceuticals published the findings.Recommanded Product: 6149-41-3 The information in the text is summarized as follows:

The synthesis and in vitro metabolism studies of a family of specifically deuterated derivatives of dronedarone (I) are described. Metabolic stability and clearance of the parent compound are not sensitive to deuterium substitution, irresp. of the position of the heavy label. The results came from multiple reactions, including the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2016,Patra, Gopal C.; Pal, Sutanuka; Bhunia, Sankar C.; Hazra, Nirmal K.; Pal, Sudhir C. published 《A multi-component synthesis of functionalized O,S-dialkyldithiocarbonates》.Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published the findings.Computed Properties of C4H8O3 The information in the text is summarized as follows:

A multi-component synthesis of dithiocarbamates (xanthates) in a single pot was accomplished under very mild conditions. The S-alkyl part in the products contained functional groups. An alc. and an activated vinyl compound was capable of acting as Michael acceptor were mixed together in carbon disulfide in the presence of a tertiary amine at room temperature The method was successful with primary and secondary alcs. in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) as catalyst. The yields were excellent. The Morita-Baylis-Hillman reaction derived allylic alcs. however behaved a little differently, and the method was utilized to prepare trisubstituted alkenes possessing thioether moiety and some biol. important thiochromenes. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Computed Properties of C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics