Category: 6149-41-3

In 2013,Zheng, Jianwei; Lin, Haiqiang; Wang, Ya-nan; Zheng, Xinlei; Duan, Xinping; Yuan, Youzhu published 《Efficient low-temperature selective hydrogenation of esters on bimetallic Au-Ag/SBA-15 catalyst》.Journal of Catalysis published the findings.Product Details of 6149-41-3 The information in the text is summarized as follows:

Gold (Au)-silver (Ag) bimetallic catalyst supported on ordered mesoporous silica SBA-15 exhibits unprecedentedly high activity and superior stability for the selective hydrogenation of di-Me oxalate to Me glycolate at a low temperature of 418 K. By contrast, monometallic Au/SBA-15 and Ag/SBA-15 catalysts are almost inactive under identical conditions. A combined tuning of particle dispersion and its surface electronic structure is shown as a consequence of the changes in the size and valence band structure of Au and Ag, which leads to significantly enhanced synergy. Considerably reduced apparent activation energies indicate that special active sites with the ability to activate substrate mols. more efficiently are generated in Au-Ag alloy nanoparticles. The Au-Ag bimetallic catalyst also displays excellent activity for the selective hydrogenation of some other unsaturated or saturated esters and acetic acid. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-hydroxypropanoate(cas: 6149-41-3Product Details of 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2015,Neubert, Timothy D.; Schmidt, Yvonne; Conroy, Erica; Stamos, Dean published 《Radical Mediated C-H Functionalization of 3,6-Dichloropyridazine: Efficient Access to Novel Tetrahydropyridopyridazines》.Organic Letters published the findings.Category: esters-buliding-blocks The information in the text is summarized as follows:

A radical mediated C-H functionalization of 3,6-dichloropyridazine using primary alcs., t-BuOOH, and TiCl3 to access alkoxy pyridazines is described. This transformation is conducted open to air and on gram scale. A subsequent cyclization step can then be employed to efficiently access diversely substituted tetrahydropyridopyridazines, e.g., I (X-rays single crystal structure shown), with multiple functional handles. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Category: esters-buliding-blocks)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Continuous catalytic process for the selective dehydration of glycerol over Cu-based mixed oxide》 was published in Journal of Catalysis in 2020. These research results belong to Mazario, Jaime; Concepcion, Patricia; Ventura, Maria; Domine, Marcelo E.. Recommanded Product: 6149-41-3 The article mentions the following:

The selective dehydration of glycerol to hydroxyacetone (acetol) was studied with Cu-based mixed oxides derived from hydrotalcite as catalysts in a continuous flow fix-bed reactor. Catalysts were prepared by co-precipitation and characterized by ICP, N2 adsorption, XRD, NH3-TPD, CO2-TPD, TPR and TEM. Different parameters were investigated to develop the most appropriate material as well as to determine the function of every metallic species. The optimized Cu-Mg-AlOx offered ≈60% acetol selectivity at >90% glycerol conversion (≈80% liquid yield, up to TOS = 9 h). The catalyst could be regenerated by calcination, achieving full activity recovery after five re-cycles. “”In-situ”” FTIR and XPS measurements evidenced that the presence of Cu, specially the most active Cu1+ species, was essential to carry out the dehydration to acetol with high reaction rates, and to form the preferred intermediate (with C=O group); although a minor contribution from Cu0 and Cu2+ species could not be discarded. In addition to this study using Methyl 3-hydroxypropanoate, there are many other studies that have used Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: 6149-41-3) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cai, Chen-Yan; Wu, Zheng-Jian; Liu, Ji-Ying; Chen, Ming; Song, Jinshuai; Xu, Hai-Chao published their research in Nature Communications in 2021. The article was titled 《Tailored cobalt-salen complexes enable electrocatalytic intramolecular allylic C-H functionalizations》.Category: esters-buliding-blocks The article contains the following contents:

Oxidative allylic C-H functionalization is a powerful tool to streamline organic synthesis as it minimizes the need for functional group activation and generates alkenyl-substituted products amenable to further chem. modifications. The intramol. variants can be used to construct functionalized ring structures but remain limited in scope and by their frequent requirement for noble metal catalysts and stoichiometric chem. oxidants. Here authors report an oxidant-free, electrocatalytic approach to achieve intramol. oxidative allylic C-H amination and alkylation by employing tailored cobalt-salen complexes as catalysts. These reactions proceed through a radical mechanism and display broad tolerance of functional groups and alkene substitution patterns, allowing efficient coupling of di-, tri- and even tetrasubstituted alkenes with N- and C-nucleophiles to furnish high-value heterocyclic and carbocyclic structures.Methyl 3-hydroxypropanoate(cas: 6149-41-3Category: esters-buliding-blocks) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2012,Kotionova, Tatyana; Lee, Christopher; Miedziak, Peter J.; Dummer, Nicholas F.; Willock, David J.; Carley, Albert F.; Morgan, David J.; Knight, David W.; Taylor, Stuart H.; Hutchings, Graham J. published 《Oxidative Esterification of Homologous 1,3-Propanediols》.Catalysis Letters published the findings.Recommanded Product: Methyl 3-hydroxypropanoate The information in the text is summarized as follows:

Abstract: The oxidative esterification of a homologous series of diols (1,3-propanediol, 2-methyl-1,3-propanediol and 2,2-dimethyl-1,3-propanediol) with methanol has been investigated using titania-supported gold, palladium and gold-palladium catalysts using mol. oxygen. The gold-palladium catalysts showed the highest activity and 1,3-propanediol was the most reactive while the addnl. Me groups decreased the reactivity. However, it is possible to achieve high selectivity to Me 3-hydroxypropionate and 2-methyl-3-hydroxyisobutyrate by mono-oxidations In the experiment, the researchers used Methyl 3-hydroxypropanoate(cas: 6149-41-3Recommanded Product: Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2016,Nguyen, Thuy Linh; Ferrie, Laurent; Figadere, Bruno published 《Synthesis of 3,5-disubstituted-1,2-dioxolanes: access to analogues of mycangimycin and some rearrangement products》.Tetrahedron Letters published the findings.Name: Methyl 3-hydroxypropanoate The information in the text is summarized as follows:

Mycangimycin is a eicosa-heptenic acid containing an unprecedented 3,5-disubstituted-1,2-dioxolane ring with promising anti-fungal and antimalarial activity. Most reported methods to prepare 1,2-dioxolanes are targeting 3,3,5,5-tetrasubstituted or 3,3,5-trisubstituted 1,2-dioxolanes. Thus, some methods for synthesizing these unusual 3,5-disubstituted 1,2-dioxolanes were investigated. The most promising approach was the use of a Kulinkovich reaction followed by an oxidative ring opening of the cyclopropanol with Co(acac)2 to reach the peroxy-hemiketal structure. Successive triflic acid mediated silane reduction of the corresponding peroxy-hemiketal afforded the expected 3,5-disubstituted-1,2-dioxolane ring. Through our studies, some unprecedented rearrangements of 1,2-dioxolane rings were observed, which will be discussed in this Letter. Finally, two saturated analogs I and II of mycangimycin were synthesized. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Name: Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Name: Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nifant’ev, Ilya E.; Shlyakhtin, Andrey V.; Bagrov, Vladimir V.; Tavtorkin, Alexander N.; Ilyin, Sergey O.; Gavrilov, Dmitry E.; Ivchenko, Pavel V. published an article in 2021. The article was titled 《Cyclic ethylene phosphates with (CH2)nCOOR and CH2CONMe2 substituents: synthesis and mechanistic insights of diverse reactivity in aryloxy-Mg complex-catalyzed (co)polymerization》, and you may find the article in Polymer Chemistry.Product Details of 6149-41-3 The information in the text is summarized as follows:

A novel pathway is proposed for the formation of branched poly(ethylene phosphate)s during the coordination ring-opening polymerization (ROP) of ethylene phosphates catalyzed by a 2,6-di-tert-butyl-4-methylphenoxy (BHT) magnesium complex, [(BHT)Mg(μ-OBn)(THF)]2 (Mg1). Electron-donating fragments in the substituents at the P atom of the ethylene phosphates and the stability of chelate Mg complexes were hypothesized to drive the formation of ethylene phosphate macromonomers. This hypothesis was validated through a comparative exptl. and theor. study of the ROP reactivity of the ethylene phosphates with -O(CH2)nCOOMe (n = 1-3, 5), -CH2COOtBu, -OCHMeCOOMe, and -OCH2CONMe2 substituents (1-7). In good agreement with the results of theor. modeling, glycolate- and lactate-substituted ethylene phosphates 1, 5, and 6 formed highly branched polymers, and the participation of the BHT-Mg glycolate intermediate in ROP was confirmed by the presence of -P(O)(OCH2COOMe)2 fragments in the homopolymer of 1. Notably, the reaction of amide-substituted 7 with Mg1 quant. afforded benzyl ethylene phosphate without subsequent ROP. The copolymerization of 1 with Et ethylene phosphonate furnished branched polymers, the architectures of which were determined by spectral and rheol. studies. Consequently, new -OCH2COX substituted cyclic phosphates can be used as efficient branching (X = OR) or chain termination (X = NR2) agents. In the experiment, the researchers used Methyl 3-hydroxypropanoate(cas: 6149-41-3Product Details of 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2009,Ying, Yuzhou; Feng, Kanka; Lv, Zhiguo; Guo, Zhenmei; Gao, Jinsheng published 《Study on nano copper-based catalysts for the hydrogenation of methyl 3-hydroxypropionate to 1, 3-propanediol》.Surface Review and Letters published the findings.Formula: C4H8O3 The information in the text is summarized as follows:

Nano copper-based catalysts were prepared by co-precipitation method and the performance of catalytic hydrogenation for Me 3-hydroxypropionate (MHP) to 1, 3-propanediol (1, 3-PDO) on the nano catalysts were studied under a high-pressure microcontinuum fixed-bed reactor. The effects of structure, texture, and composition of the catalysts on the catalytic performance were investigated by characterizing the catalysts with XRD, TG-DTG, SEM, and N2 adsorption/desorption anal. technique. The results showed that addition of promoters enhanced the activity and selectivity of copper-based catalysts, which promoted the dispersion of the active components effectively and stabilized the active center of the catalysts. Especially, the copper-based catalyst of loaded P could restrain side-reaction effectively and improve selectivity obviously, the conversion of MHP and the selectivity of 1, 3-PDO could be 91.30% and reach 90.15%, resp. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-hydroxypropanoate(cas: 6149-41-3Formula: C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Formula: C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2017,Ma, Jing; Wang, Qingpeng; Huang, Zhonglv; Yang, Xiande; Nie, Quandeng; Hao, Wenpei; Wang, Peng George; Wang, Xin published 《Glycosylated Platinum(IV) Complexes as Substrates for Glucose Transporters (GLUTs) and Organic Cation Transporters (OCTs) Exhibited Cancer Targeting and Human Serum Albumin Binding Properties for Drug Delivery》.Journal of Medicinal Chemistry published the findings.Computed Properties of C4H8O3 The information in the text is summarized as follows:

Glycosylated platinum(IV) complexes were synthesized as substrates for GLUTs and OCTs for the first time, and the cytotoxicity, and detailed mechanism were determined in vitro and in vivo. Galactoside Pt(IV), glucoside Pt(IV) and mannoside Pt(IV) were highly cytotoxic and showed specific cancer-targeting properties in vitro and in vivo. Glycosylated platinum(IV) complexes 5, 6, 7 and 8 (IC50 0.24 μM-3.97 μM) had better antitumor activity of nearly 166-fold higher than the pos. controls cisplatin, oxaliplatin and satraplatin. The presence of a hexadecanoic chain allowed binding with human serum albumin (HSA) for drug delivery, which not only enhanced the stability of the inert platinum(IV) prodrugs but also decreased their reduction by reductants present in human whole blood. Their preferential accumulation in cancer cells compared to noncancerous cells (293T and 3T3 cells) suggested that they were potentially safe for clin. therapeutic use. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Computed Properties of C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Computed Properties of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Yang; Ruan, Hanying; Li, Ying; Sun, Guoliang; Liu, Xiao; He, Wenhui; Mao, Fengfeng; He, Miaomiao; Yan, Liwei; Zhong, Guocai; Yan, Huan; Li, Wenhui; Zhang, Zhiyuan published an article in 2021. The article was titled 《Potent and Specific Inhibition of NTCP-Mediated HBV/HDV Infection and Substrate Transporting by a Novel, Oral-Available Cyclosporine A Analogue》, and you may find the article in Journal of Medicinal Chemistry.Synthetic Route of C4H8O3 The information in the text is summarized as follows:

Analogs of the natural product cyclosporine A (CsA) were developed and assessed as antivirals against infection of hepatitis B virus (HBV) and its satellite hepatitis D virus (HDV). An analog termed 27A exhibits potent inhibition of HBV/HDV infection by specifically blocking viral engagement to its cellular receptor NTCP, while it lacks immunosuppressive activity found in natural CsA. I.p. injection or oral intake of 27A protects HDV-susceptible mouse model from HDV infection. 27A serves as a promising lead for the development of novel anti-HDV/HBV agents. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Synthetic Route of C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics