Category: 6149-41-3

The author of 《Structure-Activity Relationships of Au/Al2O3 Catalyst for the Selective Oxidative Esterification of 1,3-Propanediol and Methanol》 were Zhao, Guoming; Gao, Enyuan; Wan, Qiaoqiao; Liu, Qing; Liang, Junjie; Qiao, Yingyun; Zhao, Guangzhen; Tian, Yuanyu. And the article was published in ChemistrySelect in 2019. Application of 6149-41-3 The author mentioned the following in the article:

1.5 Weight % Au/Al2O3 catalysts were prepared using the deposition-precipitation or colloid-deposition method and calcined at different temperatures for the selective oxidative esterification reaction of 1,3-propanediol and methanol to form Me 3-hydroxypropionate (3-HPM). The catalysts were characterized by nitrogen adsorption, transmission electron microscopy (TEM), X-ray diffraction (XRD), UV-Vis diffuse reflectance spectroscopy, X-ray photoelectron spectra (XPS), CO2 temperature-programmed desorption (CO2-TPD) and NH3 temperature-programmed desorption (NH3-TPD). The effect of the calcination temperature of the catalyst prepared by the deposition-precipitation method on the catalytic performance for the selective oxidative esterification of 1,3-propanediol was studied. The results showed that the conversion of 1,3-propanediol and the selectivity of 3-HPM increased at first and then decreased with the increase of the calcination temperature of catalyst. The highest conversion of 1,3-propanediol and selectivity of 3-HPM at the optimal calcination temperature of 350°C were 92.0% and 88.5%, resp. Considering the effects of preparation method and calcination temperature, it could be concluded that the metallic Au nanoparticles with appropriate particle size in coordination with the suitable amount of weak and middle acid and base sites, were favorable to the oxidative esterification of 1,3-propanediol and methanol to 3-HPM. Moreover, we found that the 1.5 weight % Au/Al2O3 catalyst could be effectively recovered without obvious decline of the catalytic properties. In the experiment, the researchers used many compounds, for example, Methyl 3-hydroxypropanoate(cas: 6149-41-3Application of 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Evaluation of efficient and practical methods for the preparation of functionalized aliphatic trifluoromethyl ethers》 was written by Sokolenko, Taras M.; Dronkina, Maya I.; Magnier, Emmanuel; Yagupolskii, Lev M.; Yagupolskii, Yurii L.. Product Details of 6149-41-3This research focused ontrifluoromethyl ether preparation; trichloromethyl ether preparation fluorination; elemental chlorine xanthate chlorination; xanthate one pot oxidative desulfurization fluorination; antimony trifluoride; chlorination; fluorination; hydrogen fluoride; oxidative desulfurization-fluorination; trifluoromethyl ethers. The article conveys some information:

The “”chlorination/fluorination”” technique for aliphatic trifluoromethyl ethers, e.g., I synthesis was investigated and a range of products with various functional groups was prepared The results were compared with oxidative desulfurization-fluorination of xanthates with the same structure. The experimental process involved the reaction of Methyl 3-hydroxypropanoate(cas: 6149-41-3Product Details of 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2011,Wang, Xiangwei; Zhao, Guoming; Zou, Huibin; Cao, Yujin; Zhang, Yongguang; Zhang, Rubing; Zhang, Fan; Xian, Mo published 《The base-free and selective oxidative transformation of 1,3-propanediol into methyl esters by different Au/CeO2 catalysts》.Green Chemistry published the findings.Synthetic Route of C4H8O3 The information in the text is summarized as follows:

Different Au/CeO2 catalysts, prepared by depositing gold on different facets of ceria nanocubes ({100}), nanorods ({110} and {100}) and nanopolyhedra ({111} and {100}), were sep. characterized by means of x-ray diffraction, N2 sorption, TPD and TPR. It was found that certain types of Au/CeO2 could selectively catalyze the oxidative transformation of 1,3-propanediol in methanol to Me 3-hydroxypropionate, Me 3-methoxypropionate, Me acrylate or di-Me malonate by mol. oxygen in the absence of any base. The selectivities of these Au/CeO2 catalysts depended on the shapes of the supporting CeO2 and the reaction temperature The Au/CeO2 cube catalyst with less acidic and basic sites exhibited high selectivity towards Me 3-hydroxypropionate (93.1% at 21.6% conversion). Comparatively, selectivities towards Me acrylate (41.6% at 92.3% conversion) and Me 3-methoxypropionate (40.2% at 92% conversion) increased using Au/CeO2 rod and polyhedron catalysts, which contained more acidic and basic sites than the cube catalyst. Moreover, we found the Au/CeO2 cube catalyst could be recycled without losing the gold nanoparticles. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-hydroxypropanoate(cas: 6149-41-3Synthetic Route of C4H8O3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2003,Ocal, Nuket; Yano, Lovelle M.; Erden, Ihsan published 《Photooxygenation of the C:N bond. A mild new method for oxidative C-C cleavage》.Tetrahedron Letters published the findings.Electric Literature of C4H8O3 The information in the text is summarized as follows:

Upon photooxygenation in the presence of base, α-oximino carbonyl compounds undergo clean oxidative C-C cleavage giving rise to mixtures of esters and acids. The mechanism of these reactions involves some unusual peroxidic intermediates, including a 2,3,5-trioxapentanes.Methyl 3-hydroxypropanoate(cas: 6149-41-3Electric Literature of C4H8O3) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2006,Hayashi, Toshio; Inagaki, Takahiro; Itayama, Naohiko; Baba, Hideyuki published 《Selective oxidation of alcohol over supported gold catalysts: methyl glycolate formation from ethylene glycol and methanol》.Catalysis Today published the findings.Application In Synthesis of Methyl 3-hydroxypropanoate The information in the text is summarized as follows:

An one-step selective oxidation of primary alc. to carboxylic ester took place in liquid-phase over nano-gold particles, alone or with other metals, e.g., Bi, La, Pb, supported on metal oxides [Al2O3, TiO2, ZrO2] by mol. oxygen. The oxidation of a mixture of ethylene glycol and methanol produced Me glycolate selectively with a small amount of Me formate. The substrate-selectivity was observed clearly with Au catalyst, but not with a typical Pd or Ru catalyst, which is also capable of catalyzing the oxidative esterification of alc.Methyl 3-hydroxypropanoate(cas: 6149-41-3Application In Synthesis of Methyl 3-hydroxypropanoate) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2008,Taarning, Esben; Madsen, Anders Theilgaard; Marchetti, Jorge Mario; Egeblad, Kresten; Christensen, Claus Hviid published 《Oxidation of glycerol and propanediols in methanol over heterogeneous gold catalysts》.Green Chemistry published the findings.Electric Literature of C4H8O3 The information in the text is summarized as follows:

Aerobic oxidation of glycerol over metal oxide supported gold nanoparticles in methanol results in the formation of di-Me mesoxalate in selectivities up to 89% at full conversion. The oxidative esterification takes place in methanol, acting both as solvent and reactant, and in the presence of base. Thus, it constitutes a direct transformation of the glycerol byproduct phase from biodiesel production or from glycerol obtained e.g. by fermentation Au/TiO2 and Au/Fe2O3 was found to have similar catalytic activity, whereas Au/C was inactive. 1,2-Propanediol was oxidized to Me lactate with a selectivity of 72% at full conversion, while 1,3-propanediol yielded Me 3-hydroxypropionate with 90% selectivity at 94% conversion. Me 3-hydroxypropionate can be easily converted into Me acrylate, which is then a green polymer building block.Methyl 3-hydroxypropanoate(cas: 6149-41-3Electric Literature of C4H8O3) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C4H8O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Huang, Lele; Liu, Xu-Feng; Zou, Jinglin; Duan, Xinping; Chen, Zuo-Chang; Zhou, Zhe-Hui; Ye, Linmin; Liang, Xuelian; Xie, Su-Yuan; Yuan, Youzhu published an article in Journal of Catalysis. The title of the article was 《Atomic ruthenium stabilized on vacancy-rich boron nitride for selective hydrogenation of esters》.Application In Synthesis of Methyl 3-hydroxypropanoate The author mentioned the following in the article:

Constructing and taming metal-support interaction of atoms and/or clusters has emerged as a promising protocol to maximize the catalytic performance of noble metal-based materials. Here, we report at. ruthenium (Ru) with the oxidized state immobilized on defect-rich hexagonal boron nitride (d-BN) nanosheets and the essential interfacial electronic effect on Ru deduced from B- and N-vacancies for superior selective hydrogenation of esters. Exptl. results indicate that strong electronic interplay exists between vacancies and at. Ru species. Unlike defect-free com. hexagonal BN (h-BN), d-BN can highly stabilize the active Ru species in at. scale with oxidation state, and the obtained Ru/d-BN significantly increases the catalytic activity and durability. Specifically, the turnover frequency of Ru/d-BN is more than one order of magnitude higher than that of the conventional optimized Ag/SiO2 catalyst for the selective hydrogenation of di-Me oxalate to Me glycol. Systematic characterizations show that the Ru on B- and N-vacancies, and the defective BN serves as electron acceptor. The findings demonstrate the overall electronic effect on the electron-rich feature of Ru on d-BN, such that the electronic metal-support interactions cause the Ru species to favor the adsorption and selective scission of C-O bonds in esters, revealing a highly efficient hydrogenation catalysis. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-hydroxypropanoate(cas: 6149-41-3Application In Synthesis of Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application In Synthesis of Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2012,Husain, S. Shaukat; Pejo, Ervin; Ge, Rile; Raines, Douglas E. published 《Modifying Methoxycarbonyl Etomidate Inter-Ester Spacer Optimizes In Vitro Metabolic Stability and In Vivo Hypnotic Potency and Duration of Actionã€?Anesthesiology published the findings.SDS of cas: 6149-41-3 The information in the text is summarized as follows:

Background: Methoxycarbonyl etomidate is the prototypical very rapidly metabolized etomidate analog. Initial studies suggest that it may be too short acting for many clin. uses. We hypothesized that its duration of action could be lengthened and clin. utility broadened by incorporating specific aliphatic groups into the mol. to sterically protect its ester moiety from esterase-catalyzed hydrolysis. To test this hypothesis, we developed a series of methoxycarbonyl etomidate analogs (spacer-linked etomidate esters) containing various aliphatic-protecting groups and spacer lengths. Methods: Spacer-linked etomidate esters were synthesized and their hypnotic potencies and durations of action following bolus administration were measured in rats using a loss-of-righting reflexes assay. Octanol:water partition coefficients and metabolic half-lives in pooled rat blood were determined chromatog. Results: All spacer-linked etomidate esters produced hypnosis rapidly and in a dose-dependent manner. ED50s for loss of righting reflexes ranged from 0.69 ± 0.04 mg/kg for cyclopropyl-methoxycarbonyl metomidate to 11.1 ± 0.8 mg/kg for methoxycarbonyl metomidate. The slope of a plot of the duration of loss of righting reflexes vs. the logarithm of the dose ranged 12-fold among spacer-linked etomidate esters, implying widely varying brain clearance rates. The in vitro metabolic half-lives of these compounds in rat blood varied by more than two orders of magnitude and were diastereometrically selective. Conclusions: We created 13 new analogs of methoxycarbonyl etomidate and identified two that have significantly higher potency and potentially address the too-brief duration of action for methoxycarbonyl etomidate. This work may provide a blueprint for optimizing the pharmacol. properties of other soft drugs. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-hydroxypropanoate(cas: 6149-41-3SDS of cas: 6149-41-3)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 6149-41-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2006,Yu, K. M. Kerry; Hummeida, Ranya; Abutaki, Afaf; Tsang, Shik Chi published 《One-step catalytic cyclohexane oxidation to adipic acid using molecular oxygenã€?Catalysis Letters published the findings.Safety of Methyl 3-hydroxypropanoate The information in the text is summarized as follows:

Using combination of Mn-Co transition metal species with N-hydroxyphthalimide as a catalyst for one-step oxidation of cyclohexane with mol. oxygen in acetic acid at 353 °K can give more than 95% selectivity towards oxygenated products with adipic acid as a major product at a high conversion (ca. 78%). A turnover number of 74 for this partial oxidation are also recorded. In addition to this study using Methyl 3-hydroxypropanoate, there are many other studies that have used Methyl 3-hydroxypropanoate(cas: 6149-41-3Safety of Methyl 3-hydroxypropanoate) was used in this study.

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2007,Lotesta, Stephen D.; Hou, Yongquan; Williams, Lawrence J. published 《A Spirodiepoxide-Based Strategy to the A-B Ring System of Pectenotoxin 4》.Organic Letters published the findings.Quality Control of Methyl 3-hydroxypropanoate The information in the text is summarized as follows:

A synthesis of a pectenotoxin 4 C1-C15 segment is reported. Suitable C1-C7 I and C8-C15 II segments were prepared, coupled, converted to product III and the C3-hydroxy variant, and then cyclized. Key findings include the stereoselective conversion of the allene to the corresponding spirodiepoxide, oxidative cleavage of the p-methoxybenzyl ether, and cyclization of the spirodiepoxide to spiroketal IV. In the experimental materials used by the author, we found Methyl 3-hydroxypropanoate(cas: 6149-41-3Quality Control of Methyl 3-hydroxypropanoate)

Methyl 3-hydroxypropanoate(cas: 6149-41-3) belongs to esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of Methyl 3-hydroxypropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics