Category: 609-14-3

《Formation of trisubstituted buta-1,3-dienes and α,β-unsaturated ketones via the reaction of functionalized vinyl phosphates and vinyl phosphordiamidates with organometallic reagents》 was published in RSC Advances in 2020. These research results belong to Oeser, Petr; Koudelka, Jakub; Dvorakova, Hana; Tobrman, Tomas. Computed Properties of C7H12O3 The article mentions the following:

The reactions of vinyl phosphates and vinyl phosphordiamidates containing an ester functional group with organometallic reagents were studied. The functionalized vinyl phosphates were smoothly converted into tri- and tetrasubstituted buta-1,3-dienes via the reaction with aryllithium reagents were found. Moreover, the vinyl phosphordiamidates were converted into α,β-unsaturated ketones using Grignard reagents. Based on the performed experiments, a reaction mechanism, which was confirmed by means of the isolation of key intermediates were presented. In the experiment, the researchers used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Computed Properties of C7H12O3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Computed Properties of C7H12O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,Liu, Shuai; Zhao, Wenxuan; Li, Jin; Wu, Na; Liu, Chang; Wang, Xin; Li, Shuohao; Zhu, Yan; Liang, Yong; Cheng, Xu published an article in CCS Chemistry. The title of the article was 《Electrochemical aziridination of tetrasubstituted alkenes with ammonia》.SDS of cas: 609-14-3 The author mentioned the following in the article:

Ammonia (NH3) is an ideal nitrogen source in terms of availability, reactivity, safety, atom economy, environmental compatibility, and ease of isolation. However, its utility for amine synthesis is limited by its high bond dissociation energy, its strong coordination ability, and the difference between its reactivity and that of the product amines. Herein, authors reported the first electrochem. protocol for direct syntheses of unprotected tetrasubstituted aziridines with NH3 and alkenes in the absence of an oxidant, which are highly challenging to achieve by other methods. The combination of graphite felt as the anode material and MeOH as the solvent was the key to the success of the protocol, and the effects of these factors were investigated by means of cyclic voltammetry and d. functional theory calculations In the experimental materials used by the author, we found Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3SDS of cas: 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.SDS of cas: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2022,He, Jin-Yu; Qian, Wei-Feng; Wang, Yan-Zhao; Yao, Chaochao; Wang, Nana; Liu, Huilin; Zhong, Bing; Zhu, Cuiju; Xu, Hao published an article in Green Chemistry. The title of the article was 《Sustainable electrochemical dehydrogenative C(sp3)-H mono/di-alkylations》.Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate The author mentioned the following in the article:

Catalyst-free, direct electrooxidative phenol derivatives C(sp3)-H mono- and di-alkylation reaction were developed. In contrast to previous typical oxidative and electrochem. coupling, this electrosynthetic approach enabled selective mono- and di-alkylations through metal- and external oxidant-free mild conditions via easily available electrodes. Advances of this strategy were proven by an unparalleled broad substrate scope for efficient C-C, C-N, C-O bond formation as well as excellent site- and regioselectivity. The electrochem. selective alkylations were devoid of addnl. electrolytes, could be conducted on a gram scale, and provided the enone products by cascade electrooxidative dehydrogenation, which highlight a notable potential for further late-stage diversification. Detailed mechanistic studies allowed to delineate the exact profile of the generation of the mono- and di-alkylation events. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Application In Synthesis of Ethyl 2-methyl-3-oxobutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 609-14-3In 2022 ,《Asymmetric Coupling of β-Ketocarbonyls and Alkynes by Chiral Primary Amine/Rh Synergistic Catalysis》 was published in Organic Letters. The article was written by Zhang, Jie; Wang, Yaning; You, Chang; Shi, Mingying; Mi, Xueling; Luo, Sanzhong. The article contains the following contents:

We herein report a synergetic chiral primary amine and rhodium catalysis for asym. coupling of β-ketocarbonyls and alkynes. A series of β-ketocarbonyls could be applied to afford linear allylation products, bearing all-carbon quaternary centers in high regio- and enantioselectivities. In the experiment, the researchers used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Related Products of 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Related Products of 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kabes, Connor; Lucas, Reagan; Gunn, Jack; Gladysz, John published their research in ACS Catalysis in 2021. The article was titled 《Chiral Cobalt(III) Tris(1,2-diamine) Catalysts That Incorporate Nitrogenous Base Containing Anions for the Bifunctional Activation of Nucleophiles and Electrophiles in Enantioselective Addition Reactions》.Product Details of 609-14-3 The article contains the following contents:

Here, The lipophilic diastereomeric cobalt complexes Λ or Δ-[Co((S,S)-dpen)3]3+ 2Cl-BArf- (Λ or Δ-(S,S)-23+ 2Cl-BArf-; dpen/BArf- = 1,2-diphenylethylenediamine/B(3,5-C6H3(CF3)2)4-) ,salts of nicotinates, isonicotinates, related sulfonates, and N,N-dimethylaminobenzoate were applied addition reactions. The 6-chloronicotinate salt gaves slower rates and lower ee values, and the 6-aminonicotinate salt gave faster rates and higher ee values. The 6-Me, 2-methoxy, and unsubstituted analogs afforded intermediate results. The 6-aminonicotinate catalyst was applied to additions of di-Me malonate to aryl-substituted nitroolefins and additions of 1,3-dicarbonyl compounds to di-t-Bu azodicarboxylate, with average yields/ee values of 90%/85% and 94%/77%, resp. The authors were unaware of other ionic catalysts for which Bronsted bases was productively incorporated into the anions, which were seldom if ever purposefully functionalized in any manner. In the experimental materials used by the author, we found Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Product Details of 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Product Details of 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wu, Yinrong; Wen, Kangmei; Chen, Jiewen; Shi, Jie; Yao, Xingang; Tang, Xiaodong published an article in 2021. The article was titled 《Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds》, and you may find the article in Organic Letters.Electric Literature of C7H12O3 The information in the text is summarized as follows:

A copper-mediated decarboxylative coupling reaction between arylacetic acids and 1,3-dicarbonyl compounds was described for the synthesis of ((indolyl)methyl)-oxocycloalkyl-esters, e.g., I. Significantly, methanocycloocta[b]indoles II [R = COOEt, CONHEt, SO2Ph, etc.; R1 = H, 4-Cl, 5-Br, etc.] were also obtained by sequential intramol. dehydrocyclization process in some cases. This protocol featured a broad substrate scope, simple operations, and good yields. Moreover, the products exhibited potent antiproliferative activity against the human cancer cell lines by a MTT assay. In the experiment, the researchers used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Electric Literature of C7H12O3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.Electric Literature of C7H12O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hansen, Poul Erik; Vakili, Mohammad; Kamounah, Fadhil S.; Spanget-Larsen, Jens published their research in Molecules in 2021. The article was titled 《NH Stretching Frequencies of Intramolecularly Hydrogen-Bonded Systems: An Experimental and Theoretical Study》.Application of 609-14-3 The article contains the following contents:

The vibrational NH stretching transitions in secondary amines with intramol. NH···O hydrogen bonds were investigated by exptl. and theor. methods, considering a large number of compounds and covering a wide range of stretching wavenumbers. The assignment of the NH stretching transitions in the exptl. IR spectra was, in several instances, supported by measurement of the corresponding ND wavenumbers and by correlation with the observed NH proton chem. shifts. The observed wavenumbers were correlated with theor. wavenumbers predicted with B3LYP d. functional theory, using the basis sets 6-311++G(d,p) and 6-31G(d) and considering the harmonic as well as the anharmonic VPT2 approximation Excellent correlations were established between observed wavenumbers and calculated harmonic values. However, the correlations were non-linear, in contrast to the results of previous investigations of the corresponding OH···O systems. The anharmonic VPT2 wavenumbers were found to be linearly related to the corresponding harmonic values. The results provide correlation equations for the prediction of NH stretching bands on the basis of standard B3LYP/6-311++G(d,p) and B3LYP/6-31G(d) harmonic analyses, with standard deviations close to 38 cm-1. This is significant because the full anharmonic VPT2 anal. tends to be impractical for large mols., requiring orders of magnitude more computing time than the harmonic anal. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Application of 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Application of 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhu, Xiaoyi; Li, Ruibo; Yao, Hequan; Lin, Aijun published their research in Organic Letters in 2021. The article was titled 《Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds》.Recommanded Product: Ethyl 2-methyl-3-oxobutanoate The article contains the following contents:

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot. In the part of experimental materials, we found many familiar compounds, such as Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: Ethyl 2-methyl-3-oxobutanoate)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Recommanded Product: Ethyl 2-methyl-3-oxobutanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Chiral 1H NMR Analysis of Carbonyl Compounds Enabled by Cationic Cobalt Complex》 was published in Organic Letters in 2020. These research results belong to Jang, Sumin; Kim, Hyunwoo. Recommanded Product: 609-14-3 The article mentions the following:

The authors report a newly prepared cationic cobalt(III) complex as a general and efficient chiral solvating agent that discriminates carbonyl compounds including esters, amides, ketones, and aldehydes. This cobalt(III) complex was further utilized to directly analyze both the conversion and the enantiomeric excess at once in the asym. fluorination. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3Recommanded Product: 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. Ketones are highly reactive, although less so than aldehydes, to which they are closely related. Much of their chemical activity results from the nature of the carbonyl group. Ketones readily undergo a wide variety of chemical reactions.Recommanded Product: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Stereospecific Electrophilic Fluorocyclization of α,Β-Unsaturated Amides with Selectfluor》 was written by Fei, Haiyang; Xu, Zheyuan; Wu, Hongmiao; Zhu, Lin; Jalani, Hitesh B.; Li, Guigen; Fu, Yao; Lu, Hongjian. SDS of cas: 609-14-3 And the article was included in Organic Letters in 2020. The article conveys some information:

An efficient fluorocyclization of α,Β-unsaturated amides I (R = Ph, 4-methoxyphenyl, 4-nitrophenyl, i-Pr, n-Bu, Bn; R1 = H, Me, Et, Ph, n-Pr, cyclopropyl, 4-methylphenyl, 4-nitrophenyl; R2 = H, Me, Et, Ph, octyl, etc.; R3 = H, Me, Et, Ph, n-Pr, cyclohexyl, etc.; R4 = Me, Et, i-Pr, t-Bu) through a formal halocyclization process is developed. The reaction proceeds under transition-metal-free conditions and leads to the formation of fluorinated oxazolidine-2,4-diones II with excellent regio- and diastereoselectivity. The evaluation of the reaction mechanism based on preliminary experiments and d. functional theory calculations suggests that a synergetic syn-oxo-fluorination occurs and is followed by an anti-oxo substitution reaction. The reaction opens a new window in the field of stereospecific fluorofunctionalization. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3SDS of cas: 609-14-3)

Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.SDS of cas: 609-14-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics