Category: 604-69-3

Fabrication of Ultrafine, Highly Ordered Nanostructures Using Carbohydrate-Inorganic Hybrid Block Copolymers was written by Nishimura, Taiki;Katsuhara, Satoshi;Lee, Chaehun;Ree, Brian J.;Borsali, Redouane;Yamamoto, Takuya;Tajima, Kenji;Satoh, Toshifumi;Isono, Takuya. And the article was included in Nanomaterials in 2022.Application of 604-69-3 The following contents are mentioned in the article:

Block copolymers (BCPs) have garnered considerable interest due to their ability to form microphase-separated structures suitable for nanofabrication. For these applications, it is critical to achieve both sufficient etch selectivity and a small domain size. To meet both requirements concurrently, we propose the use of oligosaccharide and oligodimethylsiloxane as hydrophilic and etch-resistant hydrophobic inorganic blocks, resp., to build up a novel BCP system, i.e., carbohydrate-inorganic hybrid BCP. The carbohydrate-inorganic hybrid BCPs were synthesized via a click reaction between oligodimethylsiloxane with an azido group at each chain end and propargyl-functionalized maltooligosaccharide (consisting of one, two, and three glucose units). In the bulk state, small-angle X-ray scattering revealed that these BCPs microphase separated into gyroid, asym. lamellar, and sym. lamellar structures with domain-spacing ranging from 5.0 to 5.9 nm depending on the volume fraction. Addnl., we investigated microphase-separated structures in the thin film state and discovered that the BCP with the most asym. composition formed an ultrafine and highly oriented gyroid structure as well as in the bulk state. After reactive ion etching, the gyroid thin film was transformed into a nanoporous-structured gyroid SiO₂ material, demonstrating the material’s promising potential as nanotemplates. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 纬-valerolactone.Application of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells was written by Deen, Matthew C.;Zhu, Yanping;Gros, Christina;Na, Na;Gilormini, Pierre-Andre;Shen, David L.;Bhosale, Sandeep;Anastasi, Nadia;Wang, RuiQi;Shan, Xiaoyang;Harde, Eva;Jagasia, Ravi;Lynn, Francis C.;Vocadlo, David J.. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2022.COA of Formula: C16H22O11 The following contents are mentioned in the article:

Loss of activity of the lysosomal glycosidase 尾-glucocerebrosidase (GCase) causes the lysosomal storage disease Gaucher disease (GD) and has emerged as the greatest genetic risk factor for the development of both Parkinson disease (PD) and dementia with Lewy bodies. There is significant interest into how GCase dysfunction contributes to these diseases, however, progress toward a full understanding is complicated by presence of endogenous cellular factors that influence lysosomal GCase activity. Indeed, such factors are thought to contribute to the high degree of variable penetrance of GBA mutations among patients. Robust methods to quant. measure GCase activity within lysosomes are therefore needed to advance research in this area, as well as to develop clin. assays to monitor disease progression and assess GCase-directed therapeutics. Here, we report a selective fluorescence-quenched substrate, LysoFQ-GBA, which enables measuring endogenous levels of lysosomal GCase activity within living cells. LysoFQ-GBA is a sensitive tool for studying chem. or genetic perturbations of GCase activity using either fluorescence microscopy or flow cytometry. We validate the quant. nature of measurements made with LysoFQ-GBA using various cell types and demonstrate that it accurately reports on both target engagement by GCase inhibitors and the GBA allele status of cells. Furthermore, through comparisons of GD, PD, and control patient-derived tissues, we show there is a close correlation in the lysosomal GCase activity within monocytes, neuronal progenitor cells, and neurons. Accordingly, anal. of clin. blood samples using LysoFQ-GBA may provide a surrogate marker of lysosomal GCase activity in neuronal tissue. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3COA of Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Porphyrin-Based Probe for Simultaneous Detection of Interface Acidity and Polarity during Lipid-Phase Transition of Vesicles was written by Majumder, Rini;Roy, Snigdha;Okamoto, Kentaro;Nagao, Satoshi;Matsuo, Takashi;Parui, Partha Pratim. And the article was included in Langmuir in 2020.COA of Formula: C16H22O11 The following contents are mentioned in the article:

Biochem. activities at a membrane interface are affected by local pH/polarity related to membrane lipid properties including lipid dynamics. pH and polarity at the interface are two highly interdependent parameters depending on various locations from the water-exposed outer-surface to the less-polar inner-surface. The optical response of common pH or polarity probes are affected by both the local pH and polarity; therefore, estimation of these values using two sep. probes localized at different interface depths can be erroneous. To estimate interface pH and polarity at an identical interface depth, we synthesized a glucose-pendant porphyrin (GPP) mol. for simultaneous pH and polarity detection by a single optical probe. pH-induced protonation equilibrium and polarity-dependent pi-pi stacking aggregation for GPP are exploited to measure pH and polarity changes at the 1,2-dimyristoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DMPG) membrane inter-face during DMPG phase transition. An NMR study confirmed that GPP is located at the interface Stern layer of DMPG large unilamellar vesicle (LUV). Using UV-vis absorption studies with an adapted anal. protocol, we estimated interface pH, or its deviation from the bulk phase value (螖pH), and the interface polarity simultaneously using the same spectra for sodium dodecyl sulfate (SDS) micelle and DMPG LUV. During temperature dependent gel to liquid-crystalline phase transition of DMPG, there was 鈭?.5 unit increase in 螖pH from approx. 鈭?.6 to 鈭?.1, with a small increase in interface dielec. constant from 鈭?0 to 63. A series of spectroscopic data indicate the utility of GPP for evaluation of local pH/polarity change during lipid phase transition of vesicles. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3COA of Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.COA of Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sugar based cationic magnetic core-shell silica nanoparticles for nucleic acid extraction was written by Ali, Tammar Hussein;Mandal, Amar Mousa;Heidelberg, Thorsten;Hussen, Rusnah Syahila Duali. And the article was included in RSC Advances in 2022.COA of Formula: C16H22O11 The following contents are mentioned in the article:

Nucleic acid (NA) extraction is an essential step in mol. testing for a wide range of applications. Conventional extraction protocols usually suffer from time consuming removal of non-nucleic acid impurities. In this study, a new magnetic nanoparticle (MNP) is presented to simplify the NA extraction A core-shell design, comprising of a ferromagnetic core coated with mesoporous silica, forms the basis of the functional nanoparticle. Chem. functionalization of the silica coating includes a multistep synthesis, in which an activated nanoparticle is coupled with a triethylene glycol spaced glycosyl imidazole. The mol. design aims for charge interactions between the imidazolium-based pos. nanoparticle surface and nucleic acids, with specific hydrogen bonding between the surface bonded carbohydrate and nucleic acid targets to ensure nucleic acid selectivity and avoid protein contamination. Two different carbohydrates, differing in mol. size, were selected to compare the efficiency in terms of NA extraction A triethylene glycol spacer provides sufficient flexibility to remove particle surface constraints for the interaction. The Brunauer-Emmett-Teller (BET) anal. shows a significantly larger surface area for the disaccharide-based particles NpFeSiImMalt (鈭?81 m2 g-1) compared to the monosaccharide analog NpFeSiImGlc (鈭?16 m2 g-1) at small particles sizes (range 鈭?15 nm) and sufficient magnetization (29 emu g-1) for easy isolation by an external magnetic field. The particles enabled a high DNA particle loading ratio of 30-45 wt% (MNP/DNA ratio), reflecting an efficient extraction process. A high desorption rate (7 min) with more than 86% of unchanged DNA loading was recorded, indicating low damage to the target extract This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3COA of Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.COA of Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Active site architecture of an acetyl xylan esterase indicates a novel cold adaptation strategy was written by Zhang, Yi;Ding, Hai-Tao;Jiang, Wen-Xin;Zhang, Xia;Cao, Hai-Yan;Wang, Jing-Ping;Li, Chun-Yang;Huang, Feng;Zhang, Xi-Ying;Chen, Xiu-Lan;Zhang, Yu-Zhong;Li, Ping-Yi. And the article was included in Journal of Biological Chemistry in 2021.Reference of 604-69-3 The following contents are mentioned in the article:

SGNH-type acetyl xylan esterases (AcXEs) play important roles in marine and terrestrial xylan degradation, which are necessary for removing acetyl side groups from xylan. However, only a few cold-adapted AcXEs have been reported, and the underlying mechanisms for their cold adaptation are still unknown because of the lack of structural information. Here, a cold-adapted AcXE, AlAXEase, from the Arctic marine bacterium Arcticibacterium luteifluviistationis SM1504^T was characterized. AlAXEase could deacetylate xylooligosaccharides and xylan, which, together with its homologs, indicates a novel SGNH-type carbohydrate esterase family. AlAXEase showed the highest activity at 30 掳C and retained over 70% activity at 0 掳C but had unusual thermostability with a T_m value of 56 掳C. To explain the cold adaptation mechanism of AlAXEase, we next solved its crystal structure. AlAXEase has similar noncovalent stabilizing interactions to its mesophilic counterpart at the monomer level and forms stable tetramers in solutions, which may explain its high thermostability. However, a long loop containing the catalytic residues Asp200 and His203 in AlAXEase was found to be flexible because of the reduced stabilizing hydrophobic interactions and increased destabilizing asparagine and lysine residues, leading to a highly flexible active site. Structural and enzyme kinetic analyses combined with mol. dynamics simulations at different temperatures revealed that the flexible catalytic loop contributes to the cold adaptation of AlAXEase by modulating the distance between the catalytic His203 in this loop and the nucleophilic Ser32. This study reveals a new cold adaptation strategy adopted by the thermostable AlAXEase, shedding light on the cold adaptation mechanisms of AcXEs. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Worm-like micelles and vesicles formed by alkyl-oligo(ethylene glycol)-glycoside carbohydrate surfactants: The effect of precisely tuned amphiphilicity on aggregate packing was written by Moore, Jackson E.;McCoy, Thomas M.;Sokolova, Anna V.;de Campo, Liliana;Pearson, Graeme R.;Wilkinson, Brendan L.;Tabor, Rico F.. And the article was included in Journal of Colloid and Interface Science in 2019.Electric Literature of C16H22O11 The following contents are mentioned in the article:

Carbohydrates are appealing non-ionic surfactant head-groups as they are naturally abundant, generally biocompatible and biodegradable, and readily functionalized. Recent work has produced a promising mol. candidate for the formation of viscoelastic worm-like micellar solutions: a tri(ethylene glycol)-linked oleyl-尾-D-glucoside surfactant (GlcC18:1) exhibited near ideal Maxwell behavior at low concentrations (2.9 wt%) without additives at room temperature Here, fourteen surfactants have been synthesized with structural variations based around GlcC18:1. Each contain an oligo(ethylene glycol) linker of varying length (2, 3, 4, 6 EO units) between a carbohydrate head-group (glucose, galactose, mannose, maltose, lactose, cellobiose) and a cis-unsaturated alkyl tail-group (oleyl, linoleyl, erucyl). The aqueous adsorption kinetics and self-assembly of these surfactants was explored using tensiometry and small-angle neutron scattering (SANS), resp. With SANS we observed the formation of worm-like micelles for four surfactants, and vesicles for two surfactants which exhibited behavior similar to insoluble lipids. We also observed temperature-induced micellar elongation due to dehydration of the oligo(ethylene glycol) linker, resulting in a further three surfactants forming worm-like micelles at 50 掳C. Worm-like micellar fluids were further characterized using rheol. to reveal two surfactants with vastly superior viscoelastic properties compared to GlcC18:1, with > 2 orders of magnitude increase in viscosity and > 3 orders of magnitude increase in stress relaxation time. These results provide insight into structure-function relationships for non-ionic surfactants and demonstrate a class of designed amphiphiles with a special propensity for forming viscoelastic worm-like micellar solutions at low concentrations This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Electric Literature of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rheological behaviour of thermotropic and lyotropic liquid crystalline phases of Guerbet branched chain glycolipids was written by Mislan, Azwa Amanina;Foong, J. L. Nigel;Saharin, Siti Munirah;Zahid, N. Idayu. And the article was included in Fluid Phase Equilibria in 2019.Computed Properties of C16H22O11 The following contents are mentioned in the article:

Glycolipids, being low toxicity, biodegradable and showing surface activity, are a candidate for an alternative surfactant known as biosurfactant. In this study, two Guerbet branched chain glycolipids namely 2-hexyl-decyl-尾-D-glucoside (尾-Glc-C₁₀C₆) and 2-hexyl-decyl-尾-D-maltoside (尾-Mal-C₁₀C₆) were prepared and their mesomorphic behaviors in dry and hydrated conditions were characterized and compared using rheol. These glycolipids possessed the same number of carbons in their alkyl chain but differed in headgroup size. 尾-Glc-C₁₀C₆ exhibited inverse hexagonal phase (H₂) in thermotropic but formed inverse bicontinuous cubic phase (V₂) of space group Ia3d and Pn3m upon contact with water at different concentration ranges. The self-assembly of 尾-Mal-C₁₀C₆ was dominated by the lamellar phase (L_伪) in both conditions. A shear viscosity test indicated that all mesophases formed by these Guerbet glycolipids exhibited shear thinning behavior. Oscillation measurements were obtained within the linear viscoelastic regime. In general, the viscoelastic studies on the thermotropic H₂ (尾-Glc-C₁₀C₆) and L_伪 (尾-Mal-C₁₀C₆) phases showed that the storage modulus (G鈥? and loss modulus (G鈥测€? increased with the frequency, indicating the typical viscoelastic response for non-Newtonian fluid at the selected temperatures The lyotropic inverse bicontinuous cubic of 尾-Glc-C₁₀C₆ containing different water concentrations showed the dominance of G鈥?over G” at the range of frequencies and temperatures tested. A similar finding was observed for the lyotropic L_伪 phase of 尾-Mal-C₁₀C₆ but with a lower magnitude of structural strength. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Computed Properties of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 纬-valerolactone.Computed Properties of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glucose-Sensitive Core-Cross-Linked Nanoparticles Constructed with Polyphosphoester Diblock Copolymer for Controlling Insulin Delivery was written by Li, Hongping;Zhou, Ru;He, Jinlin;Zhang, Mingzu;Liu, Jian;Sun, Xingwei;Ni, Peihong. And the article was included in Bioconjugate Chemistry in 2021.SDS of cas: 604-69-3 The following contents are mentioned in the article:

This work aims to construct biocompatible, biodegradable core-cross-linked and insulin-loaded nanoparticles which are sensitive to glucose and release insulin via cleavage of the nanoparticles in a high-concentration blood glucose environment. First, a polyphosphoester-based diblock copolymer (PBYP-g-Gluc)-b-PEEP was prepared via ring-opening copolymerization (ROP) and the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) in which PBYP and PEEP represent the polymer segments from 2-(but-3-yn-1-yloxy)-2-oxo-1,3,2-dioxaphospholane and 2-ethoxy-2-oxo-1,3,2-dioxaphospholane, resp., and Gluc comes from 2-azidoethyl-尾-D-glucopyranoside (Gluc-N3) that grafted with PBYP. The structure and mol. weight of the copolymer were characterized by ¹H NMR, ³¹P NMR, GPC, FT-IR, and UV-vis measurements. The amphiphilic copolymer could self-assemble into core-shell uncore-cross-linked nanoparticles (UCCL NPs) in aqueous solutions and form core-cross-linked nanoparticles (CCL NPs) after adding crosslinking agent adipoylamidophenylboronic acid (AAPBA). Dynamic light scattering (DLS) and transmission electron microscopy (TEM) were used to study the self-assembly behavior of the two kinds of NPs and the effect of different Gluc group contents on the size of NPs further to verify the stability and glucose sensitivity of CCL NPs. The ability of NPs to load fluorescein isothiocyanate-labeled insulin (FITC-insulin) and their glucose-triggered release behavior were detected by a fluorescence spectrophotometer. The results of Me thiazolyl tetrazolium (MTT) assay and hemolysis activity experiments showed that the CCL NPs had good biocompatibility. An in vivo hypoglycemic study has shown that FITC-insulin-loaded CCL NPs could reduce blood glucose and have a protective effect on hypoglycemia. This research provides a new method for constructing biodegradable and glucose-sensitive core-cross-linked nanomedicine carriers for controlled insulin release. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3SDS of cas: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Investigation of therapeutic effect of curcumin 伪 and 尾 glucoside anomers against Alzheimer’s disease by the nose to brain drug delivery was written by Ahmadi, Nahid;Hosseini, Mir-Jamal;Rostamizadeh, Kobra;Anoush, Mahdieh. And the article was included in Brain Research in 2021.Reference of 604-69-3 The following contents are mentioned in the article:

Alzheimer’s disease (AD) is one of the greatest geriatric medicinal challenges of our century and is the main disease leading to dementia. Despite extensive scientific research advances, available disease-modifying treatment strategies remained limited; thus, increasing demand for new drugs. In recent years, medicinal plants attracted attention due to their potential role in dementia. In the present study, 伪 and 尾 anomers of curcumin glucosides (CGs) were synthesized and evaluated for Alzheimer’s treatment. CGs were synthesized by fusion reaction as a novel and easy method with more advantages (high yield, short reaction time, and low chems.), and the products were characterized using HNMR. Wistar male rats were used to administer different treatments. They divided into control, sham, Alzheimer, and test groups (Alzheimer + 伪 anomer and Alzheimer + 尾 anomer). Animals received normal saline, Scopolamine (1 mg/kg), high dose anomers, scopolamine, and two doses (12.5 and 25 mg/kg) of anomers, resp., for 10 days. Then the Morris Water Maze (MWM) test was performed on all animals. Finally, the animals’ brains were extracted and homogenized for glutathione, acetylcholine esterase activity, protein carbonyl, and lipid peroxide level detection. The escape latency and the distance towards the hidden platform in Morris water maze in the Alzheimer group were significantly higher than both the control and test groups. Besides, there were no significant differences between sham and control groups in all tests. Both anomers led to a significant increase in glutathione, and acetylcholine levels while they caused a decrease in lipid peroxidation and protein carbonyl levels in brain tissue. It seems that intranasal administration of both anomers pos. influenced maze learning in scopolamine receiving subjects. Although both anomers resulted in similar biochem. tests, a higher dose of 尾 anomer indicated better results than 伪 anomer not only in behavioral tests but also in biochem. tests. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Surface Activity of Alkoxy Ethoxyethyl 尾-D-Glucopyranosides was written by Fan, Yulin;Fu, Fang;Chen, Langqiu;Li, Jiping;Zhang, Jing. And the article was included in Journal of Agricultural and Food Chemistry in 2020.COA of Formula: C16H22O11 The following contents are mentioned in the article:

Dioxyethene fragment (-(OCH₂CH₂)₂-) was introduced into traditional alkyl 尾-D-glucopyranosides to ameliorate the water solubility, and eight nonionic surfactants, i.e., alkoxy ethoxyethyl 尾-D-glucopyranosides with alkyl chain lengths (n = 6-16), were synthesized and characterized. Their hydrophilic and lipophilic balance number, water solubility, critical micelle concentration (cmc), 纬_cmc, 螕_max, and hygroscopic rate decreased with an increase in the alkyl chain length. Hexadecoxy ethoxyethyl 尾-D-glucopyranoside had no water solubility at 25掳C. Decoxy ethoxyethyl 尾-D-glucopyranoside had the best emulsifying property in the toluene/water and n-octane/water systems and the strongest foaming property, whereas dodecoxy ethoxyethyl 尾-D-glucopyranoside had the best emulsifying property in the rapeseed oil/water system. Such 尾-D-glucopyranosides (n = 6-12) exhibited excellent surface activity. In addition, for the binary mixture of alkoxy ethoxyethyl 尾-D-glucopyranosides (n = 8, 10, 12) and sodium dodecyl sulfate or cetyl tri-Me ammonium chloride, their cmc values were lower than the pure 尾-D-glucopyranosides, indicating that they had synergistic interactions. The fan focal conic textures of alkoxy ethoxyethyl 尾-D-glucopyranosides (n = 7-16) were observed during the cooling process under a polarizing optical microscope. Alkoxy ethoxyethyl 尾-D-glucopyranosides (n = 14, 16) had the related m.ps. and the clear points with differential scanning calorimetry. With 尾-D-glucopyranosides (n = 6-16) and n-butanol as the surfactant and cosurfactant, resp., and with cyclohexane as the oil phase, the related microemulsion areas in their pseudoternary phase diagram system were investigated with the visual observation at 25掳C. Along with the slashing requirements of petroleum consumption, environmental protection, and green and sustainable development, nonionic sugar-based alkoxy ethoxyethyl 尾-D-glucopyranosides should be expected to have their potential practical application because of their strengthened hydrophilicity, improved water solubility, and enhanced surface activity. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3COA of Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is 纬-valerolactone.COA of Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics