Category: 59524-07-1

Nakamura, Rikako; Sumida, Yuto; Ohmiya, Hirohisa published an article in 2022, the title of the article was Direct Photoexcitable Iodomethylborate Enabling Cyclopropanation of Reactive Alkenes.COA of Formula: C18H17NO4 And the article contains the following content:

A radical-mediated cyclopropanation tool for reactive alkenes, including dehydroamino acids (DHAAs), e.g., benzyl 2-[bis(tert-butoxycarbonyl)amino]acrylate, has been developed based on directly photoexcitable borate generating an iodomethyl radical under visible light irradiation The borate at the excited state serves as a strong single electron reductant. Therefore, this photoexcitable borate offers a simple protocol for cyclopropanation of DHAAs to forge medicinally important cyclopropane amino acids, e.g., I. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).COA of Formula: C18H17NO4

The Article related to cyclopropane amino acid preparation photoexcitation, alkene iodomethylborate cyclopropanation, Alicyclic Compounds: Cyclopropanes and other aspects.COA of Formula: C18H17NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yang, Yong-Qing; Ji, Meng-Chen; Lu, Zheng; Jiang, Mao; Huang, Wei-Wei; He, Xue-Zhi published an article in 2016, the title of the article was Facile access to α,β-dehydroalanine and α,β-dehydroamino butyric acid derivatives from DL-serines and threonines.Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate And the article contains the following content:

Not only α,β-dehydroamino acids are important constituents for a number of bioactive peptides in nature, but also they are important building blocks for a variety of synthetic amino acids in organic synthesis. Methods to prepare dehydroamino acids have been reported extensively in the literature; however, efficient and convenient protocols are still required. Here, the authors report a convenient method to prepare dehydroalanine (ΔAla) and dehydroamino butyric acid (ΔAbu) derivatives derived from DL-serines and DL-threonines, resp. 4-Toluenesulfonyl chloride (TsCl) and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) were employed in this procedure, which carried out activation of hydroxyl group and β-elimination in one pot. Because it is convenient and easy to handle, this method will attract the attention of synthetic chemists. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

The Article related to dehydroamino acid preparation beta elimination racemic serine threonine, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Recommanded Product: Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 25, 1983, Somekh, Lila; Shanzer, Abraham published an article.Application of 59524-07-1 The title of the article was Stereospecific synthesis of α,β-dehydroamino acids from β-hydroxy α-amino acid derivatives. And the article contained the following:

β-Amino acids I (R, R1 = H, H; Me, H; H, Me; CHMe2, H; H, CHMe2; R2 = CH2Ph, R3 = CO2CH2Ph; R, R1 = Me, H; H, Me; R2 = Et, R3 = CO2CMe3) underwent stereospecific dehydration by treatment with (diethylamino)sulfur trifluoride and pyridine in CH2Cl2 to give the corresponding unsaturated amino acids II. Threo isomers of I gave (Z)-II, whereas erythro isomers of I gave (E)-II. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Application of 59524-07-1

The Article related to hydroxy amino acid dehydration stereospecific, unsaturated amino acid stereospecific synthesis, dehydroamino acid stereospecific synthesis, Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Application of 59524-07-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Weinstein, Boris; Watrin, Kerry G.; Loie, H. Jeff; Martin, Joseph C. published an article in 1976, the title of the article was Amino acids and peptides. 44. Synthesis of DL-γ-carboxyglutamic acid, new amino acid.Application of 59524-07-1 And the article contains the following content:

Benzyl Nα-benzyloxycarbonyl-L-serinate was converted into the corresponding chloralaninate derivative and alkylation with dibenzyl malonate gave racemic tribenzyl Nα-benzyloxycarbonyl-1,1,2-ethanetricarboxylate via benzyl Nα-benzyloxycarbonyl-2-methyleneglycinate. Hydrogenolysis of the triester gave the desired amino acid. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Application of 59524-07-1

The Article related to carboxyglutamic acid, glutamic acid carboxy, Synthesis of Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Application of 59524-07-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shimomura, Hiromi; Sanada, Kazuo published an article in 1980, the title of the article was Synthesis of DL-γ-carboxyglutamic acid.Computed Properties of 59524-07-1 And the article contains the following content:

DL-γ-Carboxyglutamic acid (I) was prepared from Z-DL-Ser(OTos)OBzl (II; Tos = 4-MeC6H4SO2) and Z-NH-C(=CH2)-CO2Bzl (III; Z = PhCH2O2C) through Z-NH-C[CH2(CO2Bzl)]2-CO2Bzl (IV). A reaction mixture of Z-DL-Ser-OBzl with Tos-Cl in absolute pyridine, was adsorbed on silica gel column and eluted with C6H6 to sep. 36% III and 34% II. II was added to a mixture of 50% NaH and CH2(CO2Bzl)2 in DMF under N2 to give 94% IV, which was also similarly prepared from III. IV in MeOH was hydrogenated in the presence of 10% Pd-C to give 62% I. I showed two peaks in amino acid anal., when it was eluted with buffer solutions of pH 1-3. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Computed Properties of 59524-07-1

The Article related to carboxyglutamic acid, serinate aminoacrylate reaction, Synthesis of Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Computed Properties of 59524-07-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bajusz, S.; Juhasz, A. published an article in 1976, the title of the article was Synthesis of the new amino acid γ-carboxyglutamic acid and its derivatives.Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate And the article contains the following content:

Treatment of N-tert-butoxycarbonyl- or N-benzyloxycarbonyldehydroalanine benzyl ester with di-tert-butyl malonate gave 68 and 82% of the corresponding blocked DL-γ-carboxyglutamic acid α-benzyl ester γ-tert-butyl ester, which could be deblocked with F3CCO2H. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

The Article related to carboxyglutamic acid, dehydroalanine malonate condensation, glutamic acid carboxy, Synthesis of Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.Application In Synthesis of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 18, 1980, Miller, Marvin J. published an article.COA of Formula: C18H17NO4 The title of the article was Isourea-mediated preparation of dehydro amino acids. And the article contained the following:

Z-NHCH(CHROH)CO2R1 (I; Z = PhCH2O2C; R = H, R1 = Me, CH2Ph; R, = Me, R1 = CH2Ph) were dehydrated by carbodiimides R2N:C:NR3 (R2 = R3 = CHMe2, cyclohexyl; R2 = cyclohexyl, R3 = 2-morpholinoethyl) in the presence of CuCl catalyst to give 65-96.5% Z-NHCH(:CHR)CO2R1. Ac-Cys-OCH2Ph was treated with Me2CHN:C:NCHMe2 in the presence of CuCl to give AcNHC(:CH2)CO2CH2Ph, whereas this reaction in the absence of CuCl gave [AcNHCH(CO2CH2Ph)CH2]2S. I were prepared by treating Z-NHCH(CHROH)CO2H with O-alkylisourea derivatives The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).COA of Formula: C18H17NO4

The Article related to dehydro amino acid, hydroxy amino acid dehydration carbodiimide, isourea reaction amino acid, Synthesis of Amino Acids, Peptides, and Proteins: Amino Acids and other aspects.COA of Formula: C18H17NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 1996, Molina, Pedro; Conesa, Carlota; Desamparados Velasco, M. published an article.COA of Formula: C18H17NO4 The title of the article was Iminophosphorane-mediated synthesis of 2-aminoimidazole derivatives. And the article contained the following:

A 1-pot synthesis of 4-substituted 2-aminoimidazoles based on the aza-Wittig reaction of 2-amino-3-azidoacrylates with isocyanates is described. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).COA of Formula: C18H17NO4

The Article related to aminoimidazole preparation, imidazole amino preparation, aminoazidoacrylate isocyanate aza wittig, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.COA of Formula: C18H17NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 23, 2008, Abdo, Mohannad; Knapp, Spencer published an article.Reference of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate The title of the article was Biomimetic Seleninates and Selenonates. And the article contained the following:

The synthesis of a variety of pyranose-, nucleoside-, (amino acid)-, and polyhydric-based seleninic and selenonic acids by DMDO oxidation of the corresponding selenoesters is reported, as well as some unusual coupling reactions of the seleninate and selenonate functionality with biol. nucleophilic groups (sulfhydryl, indole, phenol, imidazole, carboxamide) that are found in proteins and enzyme active sites. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Reference of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

The Article related to glycoside seleninic selenonic acid preparation, amino acid seleninic selenonic acid preparation, nucleoside seleninic selenonic acid preparation, Carbohydrates: Nucleosides and Nucleotides, Cobalamins, Riboflavin and other aspects.Reference of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On September 3, 1990, Paquet, Alenka published an article.Application of 59524-07-1 The title of the article was Preparation of dehydroalanine peptides from bis(2,2,2-trichloroethyl) and diphenyl phosphonoserine derivatives. And the article contained the following:

Preparation of dehydroalanine peptides from the corresponding bis(2,2,2-trichloroethyl) and di-Ph phosphonoserine derivatives by treatment with various organic bases is described. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Application of 59524-07-1

The Article related to phosphonoserine peptide elimination base, dehydroalanine peptide, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Application of 59524-07-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics