In 2001,European Journal of Mass Spectrometry included an article by Sawada, Masami; Takai, Yoshio; Imamura, Hiroyuki; Yamada, Hitoshi; Takahashi, Shigetoshi; Yamaoka, Hiroshi; Hirose, Keiji; Tobe, Yoshito; Tanaka, Jyuichi. HPLC of Formula: 59410-82-1. The article was titled 《Chiral recognizable host-guest interactions detected by fast-atom bombardment mass spectrometry: application to the enantiomeric excess determination of primary amines》. The information in the text is summarized as follows:
The enantiomeric excess (ee) of organic amine compounds was determined using fast-atom bombardment (FAB) mass spectrometry based on the chiral host-guest complexation systems. The method uses a 1:1 mixture of the given chiral crown ether hosts (HRRRR and HSSSS-do), one of whose enantiomers is isotopically labeled, for the ee-determination of a given amine salt guest (G+). The peak intensity ratio {I[(HRRRR+G)+]/I[(HSSSS-do+G)+] = IRIS} of the two diastereomeric host-guest complex ions clearly changes with the change in the ee of the guest. The intensity excess (Ie) of the two complex ion peaks is newly defined as Ie = (IRIS-1)/(IRIS+1). The two sets of mass spectrometrically obtained Ie values vs. a set of ee values of phenylalanine Me ester and leucine Me ester hydrochlorides show excellent linear relations through the zero point (R2 = 0.9989 and R2 = 0.9970, resp.). This indicates the potential utility of the present ee-determination method to within ± 3% ee. Also, based on the solution equilibrium distributions of the complex ions, the linearity is math. justified. Therefore, the ee-determination can be simplified as ee (%)=(|Ie|/|Ie(100)|)|100: here, Ie(100) is the corresponding Ie value obtained using an enantiomerically pure (100% ee) guest as a reference The present chiral dimethoxyphenyl crown ether host pairs employed are effective (IRIS ≃ 1.5) for the ee-determination of most α-amino acid esters, but not effective (IRIS ≃ 1.0) for most simple alkylamines. In the experimental materials used by the author, we found H-Phg-OEt.HCl(cas: 59410-82-1HPLC of Formula: 59410-82-1)
H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.HPLC of Formula: 59410-82-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics