Tang, Shi’s team published research in Organic Letters in 2018 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Product Details of 59410-82-1

《Pd-Catalyzed Divergent C(sp2)-H Activation/Cycloimidoylation of 2-Isocyano-2,3-diarylpropanoates》 was written by Tang, Shi; Yang, Sheng-Wen; Sun, Hongwei; Zhou, Yali; Li, Juan; Zhu, Qiang. Product Details of 59410-82-1 And the article was included in Organic Letters on April 6 ,2018. The article conveys some information:

A Pd-catalyzed site-selective C(sp2)-H activation/cycloimidoylation of 2-isocyano-2,3-diarylpropanoates to construct diverse cyclic imine products has been developed. Six-membered 3,4-dihydroisoquinolines containing a C3 quaternary carbon center were generated dominantly by using bulky Ad2Pn-Bu as a ligand, while five-membered 1,1-disubstituted 1H-isoindoles were formed preferentially in the presence of bidentate phosphine ligand DPPB. The selectivity for 1H-isoindole formation was enhanced by using steric hindered aryl iodides. DFT calculations suggested that the exptl. observed ligand-controlled selectivity was a result of trans effect. The results came from multiple reactions, including the reaction of H-Phg-OEt.HCl(cas: 59410-82-1Product Details of 59410-82-1)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Product Details of 59410-82-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Okada, Etsuji’s team published research in Heterocycles in 2000 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Recommanded Product: 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Okada, Etsuji; Tsukushi, Norikado published an article in Heterocycles. The title of the article was 《A facile and convenient synthetic method for fluorine-containing 1H-pyrrolo[3,2-h]quinolines》.Recommanded Product: 59410-82-1 The author mentioned the following in the article:

Aromatic nucleophilic N-N exchange reaction of N,N-dimethyl-5,7-bis(trifluoroacetyl)-8-quinolylamine with some amino acid derivatives gave the corresponding N-[5,7-bis(trifluoroacetyl)-8-quinolyl]amino acid derivatives in excellent yields. Subsequent base-catalyzed cyclization afforded fluorine-containing 1H-pyrrolo[3,2-h]quinolines in high yields. After reading the article, we found that the author used H-Phg-OEt.HCl(cas: 59410-82-1Recommanded Product: 59410-82-1)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Recommanded Product: 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Feenstra, R. W.’s team published research in Tetrahedron in 1990 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters.Synthetic Route of C10H14ClNO2 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

In 1990,Tetrahedron included an article by Feenstra, R. W.; Stokkingreef, E. H. M.; Reichwein, A. M.; Lousberg, W. B. H.; Ottenheijm, H. C. J.; Kamphuis, J.; Boesten, W. H. J.; Schoemaker, H. E.; Meijer, E. M.. Synthetic Route of C10H14ClNO2. The article was titled 《Oxidative preparation of optically active N-hydroxy-α-amino acid amides》. The information in the text is summarized as follows:

Two routes are presented for the conversion of optically active α-amino acid amides into the title compounds One route (route A) features the formation of the Schiff bases 4-MeOC6H4CH:NCHRCONH2 (R = CHMe2, CH2CHMe2, Ph, CH2Ph, CH2CH2Ph), which are subsequently oxidized to the corresponding oxaziridines I. Route B is characterized by the formation of imidazolines II (R1 = Me, CH2CHMe2, Ph, CH2Ph; R2 = H), which are hydroxylated to hydroxy derivatives II (R2 = OH). Alcoholysis of I and II in the presence of H2NOH.HCl yields the title compounds in overall yields of 65-85% (route A) and 14-21% (route B).H-Phg-OEt.HCl(cas: 59410-82-1Synthetic Route of C10H14ClNO2) was used in this study.

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters.Synthetic Route of C10H14ClNO2 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Santhosh, L.’s team published research in ChemistrySelect in 2017 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.SDS of cas: 59410-82-1 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

《Synthesis of 1,5-Disubstituted Tetrazole via Ugi Azide Reaction: An Asymmetric Induction Approach》 was published in ChemistrySelect in 2017. These research results belong to Santhosh, L.; Nagamangala, Sagar R.; Thimmalapura, Vishwanatha M.; Vommina, Sureshbabu V.. SDS of cas: 59410-82-1 The article mentions the following:

The Ugi-azide reaction of an enantiopure amino acid derived N-terminal (α-isocyanoesters) (S)-CNCH(R1)CO2R2 (R1 = CH2C6H5, Ph; R2 = Me, Et) and C-terminal isocyanides Cbz-protected amino alkyl isocyanides (S)-CNCH2CH(R3)NHCO2CH2C6H5 (R3 = i-Pr, Ph, CH2C6H5), amino acid esters NH2C(R4)CO2Me (R4 = i-Bu, Me, Ph, etc.), aldehydes such as iso-Pr aldehyde, benzaldehyde and TMS-N3 in MeOH:THF solvent system at 50 °C yielded peptidomimetics e.g., I, comprising tetrazole as amide bond isostere. Ugi-azide reaction is an isocyanide based multi-component reaction (IMCR), as a result, change in amino acid derived isocyanides had given structurally diverse products of biol. interest. Good yields of products were obtained after column purification and found to be stable for shelf storage. The present method offers several advantages such as one-pot simple procedure, high yields and easy purification of products. The experimental part of the paper was very detailed, including the reaction process of H-Phg-OEt.HCl(cas: 59410-82-1SDS of cas: 59410-82-1)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.SDS of cas: 59410-82-1 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Duhamel, Lucette’s team published research in Tetrahedron in 1988 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Recommanded Product: H-Phg-OEt.HCl

The author of 《Enantioselective electrophilic bond construction to the α-carbon of α-amino acids》 were Duhamel, Lucette; Duhamel, Pierre; Fouquay, Stephane; Eddine, Jamal Jamal; Peschard, Olivier; Plaquevent, Jean Christophe; Ravard, Alain; Solliard, Roland; Valnot, Jean Yves; Vincens, Helene. And the article was published in Tetrahedron in 1988. Recommanded Product: H-Phg-OEt.HCl The author mentioned the following in the article:

In this report, three possibilities are described for amino acid synthesis using an enantioselective electrophilic process. Thus, enantioselective carboxylation, alkylation, and protonation of Schiff bases yield optically active amino acids with an enantiomeric excess up to 76%. In the part of experimental materials, we found many familiar compounds, such as H-Phg-OEt.HCl(cas: 59410-82-1Recommanded Product: H-Phg-OEt.HCl)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Recommanded Product: H-Phg-OEt.HCl

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Brisdon, Brian J.’s team published research in Tetrahedron in 1993 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Product Details of 59410-82-1

Brisdon, Brian J.; England, Richard; Reza, Khalid; Sainsbury, Malcolm published an article on January 29 ,1993. The article was titled 《Monofunctional chiral crowns. Part 1》, and you may find the article in Tetrahedron.Product Details of 59410-82-1 The information in the text is summarized as follows:

A siloxane oligomer bearing a chiral crown with high affinity for α-amino acids has been synthesized. The host is a modified form of a coronand first prepared by Cram, in which two 1,1′-binaphthol systems are linked through the oxygen atoms at the 2,2′-positions to form a 22-membered ring system containing six ether oxygen atoms attached to each other by four ethylene units. This was selectively mono-alkenylated to form an undec-10-en-1-yl derivative, which was bonded to linear siloxanes [HSiMe2O(SiMe2O)nSiMe2H] and [Me3SiO(Me2SiO)x(MeHSiO)ySiMe3] with total chain lengths of ca. 4 and 200 Si atoms resp., via a Pt catalyzed hydrosilylation reaction. The results came from multiple reactions, including the reaction of H-Phg-OEt.HCl(cas: 59410-82-1Product Details of 59410-82-1)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Product Details of 59410-82-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rossi, Elisabetta’s team published research in Heterocycles in 1999 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Related Products of 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Related Products of 59410-82-1On June 1, 1999, Rossi, Elisabetta; Abbiati, Giorgio; Nava, Donatella published an article in Heterocycles. The article was 《1,2-Dihydro-1,3,5-triazines from 1,3-diaza-1,3-butadienes》. The article mentions the following:

4-Aryl-1-(4-methylphenyl)-2-phenyl- and 1-benzyl-2,4-diphenyl-1,3-diaza-1,3-butadienes are nearly quant. transformed into the corresponding 1,3,5-triazines when allowed to stand at room temperature in benzene solution The mechanism of the reaction is discussed. The experimental process involved the reaction of H-Phg-OEt.HCl(cas: 59410-82-1Related Products of 59410-82-1)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Related Products of 59410-82-1 They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dong, Yue’s team published research in Bioorganic Chemistry in 2020 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Electric Literature of C10H14ClNO2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Dong, Yue; Liu, Xinyong; An, Yunfei; Liu, Min; Han, Jun; Sun, Bin published an article in Bioorganic Chemistry. The title of the article was 《Potent arylamide derivatives as dual-target antifungal agents: Design, synthesis, biological evaluation, and molecular docking studies》.Electric Literature of C10H14ClNO2 The author mentioned the following in the article:

Fungal infections have become a serious medical problem due to the high infection rate and the frequent emergence of drug resistance. Ergosterol is an important structural component of the fungal cell membrane, its synthetases (squalene epoxidase (SE) and 14α-demethylase (CYP51)) are considered as the key points to block the ergosterol synthesis. In this study, we designed a series of dual-target arylamides derivatives based on the anal. of active sites (SE, CYP51). Subsequently, these target compounds were synthesized, and their antifungal activity was evaluated. Most of compounds demonstrate the potent antifungal activity against multiple Candida spp. and A. fum. In particular, the antifungal activities of compounds 10b (I) and 11c(II) are not only superior to pos. control drugs, but also have significant inhibitory effects on drug-resistant fungi (C.alb. Strain100, C.alb. Strain103). Therefore, their action mechanism was further studied. Cellular uptake and electron microscopy observation showed that target compounds were able to enter fungal cytoplasmic region through free diffusion, and destroyed cell membrane structure. At the same time, preliminary mechanisms have demonstrated that they can affect the synthesis of ergosterol by inhibiting the activity of dual targets. It is worth noting that they also can exhibit excellent antifungal activity and low toxic side effects in vivo. Their ADMET properties and binding models were established will be useful for further lead optimization. The experimental process involved the reaction of H-Phg-OEt.HCl(cas: 59410-82-1Electric Literature of C10H14ClNO2)

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Electric Literature of C10H14ClNO2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Salome, Christophe’s team published research in Tetrahedron in 2009 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Recommanded Product: 59410-82-1

Salome, Christophe; Kohn, Harold published an article on January 10 ,2009. The article was titled 《Triphenylphosphine dibromide: a simple one-pot esterification reagent》, and you may find the article in Tetrahedron.Recommanded Product: 59410-82-1 The information in the text is summarized as follows:

We report a one-pot, expedient protocol for the conversion of carboxylic acids to their esters using excess triphenylphosphine dibromide, base, and the alc. The reaction gave the esterified product in moderate-to-high yields (30-95%). For chiral acids, the reaction proceeded with little or no racemization. Use of a chiral alc. in this transformation gave the ester with retention of configuration of the stereogenic center. Information is presented indicating that esterification proceeds through the intermediate generation of an acyloxyalkoxyphosphorane and where steric interactions play an important role in the energetics of the reaction.H-Phg-OEt.HCl(cas: 59410-82-1Recommanded Product: 59410-82-1) was used in this study.

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Recommanded Product: 59410-82-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Foschi, Francesca’s team published research in Organic Letters in 2013 | CAS: 59410-82-1

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Synthetic Route of C10H14ClNO2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Foschi, Francesca; Tagliabue, Aaron; Mihali, Voichita; Pilati, Tullio; Pecnikaj, Ilir; Penso, Michele published an article in Organic Letters. The title of the article was 《Memory of Chirality Approach to the Enantiodivergent Synthesis of Chiral Benzo[d]sultams》.Synthetic Route of C10H14ClNO2 The author mentioned the following in the article:

Nonracemic polyfluorobenzo[d]sultams (polyfluorodioxobenzoisothiazolecarboxylates) such as I (R = MeO2C, Ph; R1 = Ph, MeO2C; R2 = H, EtCH2, H2C:CHCH2) were prepared using either stereoselective cyclization of nonracemic (polyfluoroarylsulfonyl)phenylglycines such as II or by phase-transfer alkylation of polyfluorobenzosultams I (R = MeO2C, Ph; R1 = Ph, t-BuO2C; R2 = H) followed by preferential crystallization of one enantiomer of the product. Starting from (polyfluoroarylsulfonyl)phenylglycines, both enantiomers of the corresponding polyfluorobenzo[d]sultams were prepared in most cases; when DBU and N,N,N’,N’-tetramethyl-N”-tert-butylguanidine (BTMG) were used as bases in 1,2-dimethoxyethane, sultams were obtained mainly with retention of the phenylglycine stereochem. (6-94% ee), while when BTMG alone in DME was used, the sultams were obtained mainly with inversion of the phenylglycine stereochem. (8-96% ee). The structures of I (R = MeO2C; R1 = Ph; R2 = EtCH2, H2C:CHCH2) and of I (R = Ph; R1 = t-BuO2C; R2 = Me) were determined by X-ray crystallog. In addition to this study using H-Phg-OEt.HCl, there are many other studies that have used H-Phg-OEt.HCl(cas: 59410-82-1Synthetic Route of C10H14ClNO2) was used in this study.

H-Phg-OEt.HCl(cas: 59410-82-1) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Synthetic Route of C10H14ClNO2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics