Category: 583-04-0

Guo, Lei published the artcileSelective, Intermolecular Alkylarylation of Alkenes via Photoredox/Nickel Dual Catalysis, Recommanded Product: Allyl benzoate, the main research area is photoredox nickel catalyzed alkylarylation alkene aryl halide alkyl oxalate.

A regioselective, intermol. 1,2-alkylarylation of alkenes with aryl halides and alkyl oxalates has been developed via photoredox/nickel dual catalysis. This dual-catalytic protocol involves a radical relay process, where radical addition is followed by a nickel-assisted coupling, forging two consecutive C-C bonds in a single operation. The mild and redox-neutral conditions allow for good compatibility in the scope of olefins, (hetero)aryl halides, as well as alkyl oxalates.

Organic Letters published new progress about Aryl halides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Recommanded Product: Allyl benzoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tu, Hai-Yong published the artcileEnantioselective Three-Component Fluoroalkylarylation of Unactivated Olefins through Nickel-Catalyzed Cross-Electrophile Coupling, Quality Control of 583-04-0, the main research area is nickel catalyzed enantioselective three component fluoroalkylarylation olefin.

A nickel-catalyzed, enantioselective, three-component fluoroalkylarylation of unactivated alkenes with aryl halides and perfluoroalkyl iodides has been described. This cross-electrophile coupling protocol utilizes a chiral nickel/BiOx system as well as a pendant chelating group to facilitate the challenging three-component, asym. difunctionalization of unactivated alkenes, providing direct access to valuable chiral β-fluoroalkyl arylalkanes with high efficiency and excellent enantioselectivity. The mild conditions allow for a broad substrate scope as well as good functional group toleration. Thus, e.g., allylic ester I + 5-bromo-2-(trifluoromethyl)pyrimidine + IC4F9 → II (87%, 94:6 er).

Journal of the American Chemical Society published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Quality Control of 583-04-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yin, Li-Ming published the artcileNickel-Catalyzed anti-Markovnikov Hydrodifluoroalkylation of Unactivated Alkenes, Application In Synthesis of 583-04-0, the main research area is alkene difluoroalkyl bromide nickel catalyst regioselective anti Markovnikov hydrodifluoroalkylation; ethyldifluorooxo phenylamino alkanoate preparation.

An efficient Ni-catalyzed hydrodifluoroalkylation of unactivated alkenes with bromodifluoroacetate by using PhSiH3 as hydride source was developed. The transformation affords aliphatic difluorides with anti-Markovnikov regioselectivity. A wide range of highly remote alkenes, simple alkenes, drug mols., com. available CF2 precursors, and even nonfluorinated substrates are competent in this reaction under mild conditions, demonstrating the practicability of the strategy. Moreover, mechanistic studies indicated that the difluoroalkyl radical might be a key intermediate to this transformation.

Organic Letters published new progress about Aromatic amides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Application In Synthesis of 583-04-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhou, Minqi published the artcileNickel-Catalyzed Four-Component Carbocarbonylation of Alkenes under 1 atm of CO, Category: esters-buliding-blocks, the main research area is nickel catalyzed four component carbocarbonylation alkene.

Transition-metal-catalyzed carbonylation is one of the most straightforward strategies to prepare carbonyl compounds However, compared to well-established noble-metal-catalyzed carbonylation reactions, analog coupling via base-metal, nickel catalysis has received less attention because of the easy formation of highly toxic and unreactive Ni(CO)4 species between Ni(0) and CO. To date, the use of inexpensive and widely available carbon monoxide (CO) gas for nickel-catalyzed carbonylation reaction remains challenging, and nickel-catalyzed four-component carbonylative reaction has not been reported yet. Here, we report a highly selective nickel-catalyzed four-component carbocarbonylation of alkenes under 1 atm (1 atm) of CO gas to efficiently achieve an array of complex carbonyl compounds, including fluorinated amino acids and oligopeptides of great interest in medicinal chem. and chem. biol. This reaction relies on a nickel-catalyzed one-pot cascade process to assemble CO, arylboronic acids, and difluoroalkyl electrophiles across the carbon-carbon double bond of alkenes, paving a new way for base-metal-catalyzed carbonylative cascade reaction.

Journal of the American Chemical Society published new progress about Amino acids, protected Role: SPN (Synthetic Preparation), PREP (Preparation). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nie, Xingliang published the artcileRadical Fluorosulfonylation: Accessing Alkenyl Sulfonyl Fluorides from Alkenes, Safety of Allyl benzoate, the main research area is alkenyl sulfonyl fluoride synthesis radical fluorosulfonylation alkene; SuFEx; alkenes; radical reactions; sulfonyl fluorides; visible light.

Sulfonyl fluorides have widespread applications in many fields. In particular, their unique biol. activity has drawn considerable research interest in the context of chem. biol. and drug discovery in the past years. Therefore, new and efficient methods for the synthesis of sulfonyl fluorides are highly in demand. In contrast to extensive studies on FSO2+-type reagents, a radical fluorosulfonylation reaction with a fluorosulfonyl radical (FSO2.) remains elusive so far, probably owing to its instability and difficulty in generation. Herein, the development of the first radical fluorosulfonylation of alkenes based on FSO2 radicals generated under photoredox conditions is reported. This radical approach provides a new and general access to alkenyl sulfonyl fluorides, including structures that would otherwise be challenging to synthesize with previously established cross-coupling methods. Moreover, extension to the late-stage fluorosulfonylation of natural products is also demonstrated.

Angewandte Chemie, International Edition published new progress about Alkylation, homolytic. 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Safety of Allyl benzoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Peng-Wei published the artcileCobalt-Catalyzed Intermolecular Hydroamination of Unactivated Alkenes Using NFSI as Nitrogen Source, Related Products of esters-buliding-blocks, the main research area is diphenylsulfonimide preparation chemoselective regioselective; alkene fluorobenzenesulfonimide cobalt hydroamination.

Comprehensive Summary : Cheap metal (Fe, Mn, and Co)-catalyzed hydroamination of alkenes has been an attractive method for synthesis of amines because of biocompatibility of metal, excellent Markovnikov selectivity and chemoselectivity. However, most reports are limited to unsaturated nitrogen sources (nitric oxide, azos, azides, cyano, etc.), for which aminated products are very limited. Notably, while used widely for fluorinating reaction, N-fluorobenzenesulfonimide (NFSI) as amine source for hydroamination has seldom been reported. Here authors developed a cobalt-catalyzed intermol. hydroamination of unactivated alkenes using NFSI as nitrogen source under mild conditions. The reaction exhibits excellent chemo- and regio-selectivity with no hydrofluorination or linear-selectivity products. Notably, the reaction proceeded with excellent yield even though the amount of Co(salen) catalyst was reduced to 0.2 mol%. Recently, a similar work was also reported by Zhang and coworkers (reference 19).

Chinese Journal of Chemistry published new progress about Benzenesulfonamides Role: SPN (Synthetic Preparation), PREP (Preparation). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Peng published the artcileAuto-Tandem Cooperative Catalysis Using Phosphine/Palladium: Reaction of Morita-Baylis-Hillman Carbonates and Allylic Alcohols, Name: Allyl benzoate, the main research area is spirooxindole preparation chemoselective regioselective diastereoselective; carbonate allylic alc tandem phosphine palladium catalyst; Lewis base; allylic compounds; annulations; cooperative catalysis; palladium.

Auto-tandem catalysis (ATC), in which a single catalyst promotes two or more mechanistically different reactions in a cascade pattern, provides a powerful strategy to prepare complex products from simple starting materials. An unprecedented auto-tandem cooperative catalysis (ATCC) for Morita-Baylis-Hillman carbonates from isatins I [X = CH, N; R = H, 5-OCH3, 5,7-(CH3)2, etc.; R1 = CH3, C6H5CH2; R2 = OC(CH3)3, CH3, OCH2CH3] and allylic carbonates R4CH=CHCH(R3)OC(O)OC(CH3)3 [R3 = R4 = H; R3 = CH2=CH, 4-H3CC6H4, pyridin-3-yl, cyclohexyl, etc.; R4 = CH3] using a simple Pd(PPh3)4 precursor has been reported. Dissociated phosphine generates phosphorus ylides and the Pd leads to π-allylpalladium complexes, and they undergo a γ-regioselective allylic-allylic alkylation reaction. Importantly, a cascade intramol. Heck-type coupling proceeds to finally furnish spirooxindoles II incorporating a 4-methylene-2-cyclopentene motif. Exptl. results indicate that both Pd and phosphine play crucial roles in the catalytic Heck reaction. In addition, the asym. versions with either a chiral phosphine e.g., III or chiral auxiliary are explored, and moderate results are obtained.

Angewandte Chemie, International Edition published new progress about Carbonates Role: RCT (Reactant), RACT (Reactant or Reagent) (Morita-Baylis-Hillman). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Name: Allyl benzoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Huiqing published the artcileSynthesis and catalysis of a Z-stereoretentive ruthenium carbene catalyst chelated by 2,4,5,7-tetrachloro-1,8-dimercaptonaphthalene for olefin metathesis, COA of Formula: C10H10O2, the main research area is alkenyl alc diastereoselective preparation; terminal alkene butenediol ruthenium heterocyclic carbene catalyst cross metathesis.

An 2,4,5,7-tetrachloro-1,8-dimercaptonaphthalene ligand-chelated ruthenium-based carbene olefin metathesis catalyst was synthesized. The synthesized catalyst catalyzed the ring-opening cross-metathesis reactions of norbornene/exo,exo-5-norbornene-2,3-dimethanol with styrene/4-fluorostyrene to obtain high Z-products (97:3-99:1 Z/E). The cross-metathesis reactions of (Z)-2-butene-1,4-diol with terminal alkenes using the synthesized catalyst gave high Z-stereoretentive products (91:9-98:2 Z/E). Compared to the previously reported Ru catalysts with naphthalene-1,8-dithiolate and 1,2-dicarbadodecaborane (12)-1,2-dithiolate, the prepared Ru complex exhibited higher catalytic activity under similar catalytic conditions. In addition, the new catalyst tolerated various olefin substrates containing different functional groups.

New Journal of Chemistry published new progress about Carbene complexes, N-heterocyclic, transition metal complexes Role: CAT (Catalyst Use), USES (Uses). 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, COA of Formula: C10H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rodriguez, Jessica published the artcileAu(I)/Au(III) Catalytic Allylation Involving π-Allyl Au(III) Complexes, Formula: C10H10O2, the main research area is branched allylated indole preparation; allyl compound indole cross coupling gold catalyst.

A (MeDalphos)AuCl complex was found to efficiently catalyze the cross-coupling of indoles and allyl acetates/alcs. The reaction tolerated many functional groups and selectively affords the branched C3-allylated products from both α- and γ-substituted allyl substrates. It took the advantage of the hemilabile character of the PN ligand. The C(sp2)-C(sp3) coupling operated via a Au(I)/Au(III) redox cycle and involves a dicationic π-allyl Au(III) complex as a key intermediate. In this case, the allyl moiety adopted an asym. σ + π-coordination mode, as substantiated by NMR spectroscopy and d. functional theory (DFT) calculations

ACS Catalysis published new progress about Cross-coupling reaction. 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Formula: C10H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ano, Yusuke published the artcilePalladium-catalyzed 1,1-alkynylbromination of alkenes with alkynyl bromides, Product Details of C10H10O2, the main research area is propargylic bromide preparation regioselective; alkynyl bromide terminal alkene alkynylbromination palladium catalyst.

The palladium-catalyzed 1,1-alkynylbromination of terminal alkenes RC=CH2 (R = Ph, naphthalen-2-yl, 1-benzofuran-2-yl, etc.) with a (bromoethynyl)triisopropylsilane is reported. The method tolerates a diverse range of alkenes to afford propargylic bromides RCH2CH(Br)CCSi(CH(CH3)2)3 regioselectively. Mechanistic studies and DFT calculations indicate that the 1,1-alkynylbromination reaction proceeds via the migration of the Pd center followed by the formation of a π-allenyl Pd intermediate, leading to the stereoselective reductive elimination of the C(sp3)-Br bond at the propargylic position.

Chemical Science published new progress about Bromination catalysts. 583-04-0 belongs to class esters-buliding-blocks, name is Allyl benzoate, and the molecular formula is C10H10O2, Product Details of C10H10O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics