Category: 555-43-1

555-43-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 555-43-1, name is Propane-1,2,3-triyl tristearate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Into a single-necked reaction flask, 1 equivalent of myristin (0.27 g, 0.37 mmol) and 3 equivalents of 11-(hexadecylthio)undecan-1-ol (0.48 g, 1.12 mmol) were added. After the addition of the catalyst (0.030 g, 15 mmol%), the mixture was heated with stirring in glycerin bath at 110 C (bath temperature) for 6 h, at the end of which the reaction mixture was cooled and sufficient amount of MeOH was added. The resulting solid product was filtered under vacuum and washed successfully with MeOH. The yield of 11-(hexadecylthio)undecyl tetradecanoate was 0.67 g, 93%. The productis of sufficient purity for further spectroscopic analysis.

The synthetic route of Propane-1,2,3-triyl tristearate has been constantly updated, and we look forward to future research findings.

Reference:
Article; Y?ld?r?m, Ayhan; K?raylar, Kaan; Oeztuerk, Serkan; Research on Chemical Intermediates; vol. 46; 1; (2020); p. 215 – 230;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthetic Route of 555-43-1, A common heterocyclic compound, 555-43-1, name is Propane-1,2,3-triyl tristearate, molecular formula is C57H110O6, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: An assay mixture consisting of 1 ml of liquid ester or 1 g of solid ester, 3 ml of isopropanol, 5 ml of phosphate buffer (pH=8.0), and 1 ml of the lipase solution was incubated for 15 min at 30C with stirring at 180 rpm. The reaction was terminated by the addition of 95% ethanol, and the amount of liberated fatty acids after incubation was determined by titrating with 50 mM NaOH in the presence of two drops of phenolphthalein solution as the indicator. The control experiment was performed under the same conditions with the addition of 95% ethanol prior to the reaction. One unit of lipase activity was defined as the amount of enzyme required to liberate 1 mumol of free fatty acid per minute under the experimental conditions.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Li, Xiao-Lu; Zhang, Wen-Hui; Wang, Ying-Dong; Dai, Yu-Jie; Zhang, Hui-Tu; Wang, Yue; Wang, Hai-Kuan; Lu, Fu-Ping; Journal of Molecular Catalysis B: Enzymatic; vol. 102; (2014); p. 16 – 24;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of 555-43-1, A common heterocyclic compound, 555-43-1, name is Propane-1,2,3-triyl tristearate, molecular formula is C57H110O6, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Into a single-necked reaction flask, 1 equivalent of myristin (0.27 g, 0.37 mmol) and 3 equivalents of 11-(hexadecylthio)undecan-1-ol (0.48 g, 1.12 mmol) were added. After the addition of the catalyst (0.030 g, 15 mmol%), the mixture was heated with stirring in glycerin bath at 110 C (bath temperature) for 6 h, at the end of which the reaction mixture was cooled and sufficient amount of MeOH was added. The resulting solid product was filtered under vacuum and washed successfully with MeOH. The yield of 11-(hexadecylthio)undecyl tetradecanoate was 0.67 g, 93%. The productis of sufficient purity for further spectroscopic analysis.

The synthetic route of 555-43-1 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Y?ld?r?m, Ayhan; K?raylar, Kaan; Oeztuerk, Serkan; Research on Chemical Intermediates; vol. 46; 1; (2020); p. 215 – 230;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application of 555-43-1,Some common heterocyclic compound, 555-43-1, name is Propane-1,2,3-triyl tristearate, molecular formula is C57H110O6, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Alcoholysis of triglycerides Alcoholysis of pure triglycerides (TGs), including trilaurin, tripalmitin and tristearin, was carried out. Most diglyceride (DG) obtained from alcoholysis reaction were 1,2-DG. A high amount OF uNREACTED TG remained in the reaction mixture. Acyl migration was observed during the reaction, especially in hydrolysis reaction, as illustrated in Figure 18. Figure 18 shows data from alcoholysis reaction showing the 1,3- DS/1, 2-DS ratio during alcoholysis and hydrolysis of tristearin. DEP = D-EP100, RM = Lipozyme RM IM, Hx = n-hexane, HYD = hydrolysis, ALC = alcoholysis. The reaction catalyzed by Lipozyme RM IMTM, though gave lower yield, showed higher acyl migration than the reaction catalyzed by D-EP100. Low acyl migration was observed in alcoholysis using CAL-B after 6h. This could be because 1,2- DG and 1,3-DG were produced at the same time according to the non-specificity of CAL- B. D-EP 100 showed higher activity than CAL-B and Lipozyme RM, respectively, in alcoholysis of tripalmitin and tristearin. Effect OF AW : HIGHER yield and less MG was obtained from alcoholysis at aW 0.11 than 0.43. It was found that MG was increased with increasing aw. Effect of solvents (on yield and acyl migration): Highest yield was obtained with MTBE. Alcoholysis in n-hexane and isooctane gave moderate yield, while acetone was a poor solvent for Lipozyme RM. The reaction performed in n- hexane showed faster acyl migration than in MTBE, as illustrated in Figures 18 and 19. Figure 19 illustrates data from the hydrolysis of trilaurin at 60C by Lipozyme RM IM (DG = dilaurin).

The synthetic route of 555-43-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; DIVERSA CORPORATION; WO2005/32496; (2005); A2;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

555-43-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 555-43-1, name is Propane-1,2,3-triyl tristearate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Into a single-necked reaction flask, 1 equivalent of myristin (0.27 g, 0.37 mmol) and 3 equivalents of 11-(hexadecylthio)undecan-1-ol (0.48 g, 1.12 mmol) were added. After the addition of the catalyst (0.030 g, 15 mmol%), the mixture was heated with stirring in glycerin bath at 110 C (bath temperature) for 6 h, at the end of which the reaction mixture was cooled and sufficient amount of MeOH was added. The resulting solid product was filtered under vacuum and washed successfully with MeOH. The yield of 11-(hexadecylthio)undecyl tetradecanoate was 0.67 g, 93%. The productis of sufficient purity for further spectroscopic analysis.

The synthetic route of Propane-1,2,3-triyl tristearate has been constantly updated, and we look forward to future research findings.

Reference:
Article; Y?ld?r?m, Ayhan; K?raylar, Kaan; Oeztuerk, Serkan; Research on Chemical Intermediates; vol. 46; 1; (2020); p. 215 – 230;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics