Category: 539-88-8

Donabauer, Karsten published the artcilePhotocatalytic Reductive Radical-Polar Crossover for a Base-Free Corey-Seebach Reaction, Product Details of C7H12O3, the main research area is hydroxymethyl dithiane preparation; dithiane photocatalytic Corey Seebach aldehyde ketone; Corey-Seebach; HAT-catalysis; carbanion; photocatalysis; radical-polar crossover.

A photocatalytic approach to the Corey-Seebach reaction has been described. The presented method operates under mild redox-neutral and base-free conditions giving the desired product with high functional group tolerance. The reaction is enabled by the combination of photo- and hydrogen atom transfer (HAT) catalysis. This catalytic merger allows a C-H to carbanion activation by the abstraction of a hydrogen atom followed by radical reduction The generated nucleophilic intermediate is then capable of adding to carbonyl electrophiles. By this approach, dithianes I (R1 = Me, NCCH2CH2, PhCH2CH2, etc.) were reacted with various aldehydes and ketones R2C(O)R3 [R2 = Et, i-Pr, MeSCH2CH2, R3 = H; R2 = n-Pr, i-Pr, PhCH2CH2, etc., R3 = Me; R2R3 = (CH2)3, (CH2)2O(CH2)2, etc.] giving access to the valuable α-hydroxy dithianes II. The proposed reaction mechanism is supported by emission quenching, radical-radical homocoupling and deuterium labeling studies as well as by calculated redox-potentials and bond strengths.

Chemistry – A European Journal published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Product Details of C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Lixia published the artcileSelective aerobic oxidative cleavage of lignin C-C bonds over novel hierarchical Ce-Cu/MFI nanosheets, Recommanded Product: Ethyl 4-oxopentanoate, the main research area is zeolite MFI supported cerium copper catalyst preparation property; oxidative bond cleavage depolymerization lignin aromatic compound.

The catalytic depolymerization process for lignin to produce value added chems. is often challenged by the limited mass transfer over heterogeneous catalysts, the complex aromatic biopolymer structures, and the high recalcitrance of C-C bonds. Herein, a series of hierarchical MFI nanosheets (MFI-ns) supported metal oxide catalysts have been designed and used for the selectively oxidative cleavage of organosolv lignin. As expected, 81.6% conversion of lignin can be achieved over 15Ce-5Cu/MFI-ns with 294.0 mg g-1 yield of volatile products, including 180.9 mg g-1 of di-Et maleate. Quantum chem. calculation coupled with static adsorption measurements shows that the superior catalytic activities of these catalysts are ascribed to the favorable mass transport of lignin to the active sites by the unique layer structure, and the hierarchical pore sizes distribution, as well as the electronic effect between Cu and Ce components. In addition, the catalytic mechanism for the cleavage of C-C bonds in β-O-4 model probes has been studied via the controlled oxidative degree of model compounds and the isotope-labeling experiments Therefore, this work provides a new insight into the efficient utilization of lignin via the rational design of catalysts.

Applied Catalysis, B: Environmental published new progress about Aromatic compounds Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Recommanded Product: Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Guo, Xuan published the artcileThe Photocatalyst-Free Cross-Dehydrogenative Coupling Reaction Enabled by Visible-Light Direct Excitation of Substrate, HPLC of Formula: 539-88-8, the main research area is aryl tetrahydroisoquinoline ketone photochem dehydrogenation cross coupling reaction; dihydroisoquinolinyl ketone preparation green chem; phosphite aryltetrahydroisoquinolinyl photochem dehydrogenation cross coupling reaction; phosphonyldihydroisoquinoline aryl preparation green chem.

A new photocatalyst-free strategy for the cross-dehydrogenative C-C and C-P coupling reaction was described. This protocol provided a concise method to synthesize various 1-substituted tetrahydroisoquinoline (THIQ) derivatives enabled by visible-light direct excitation of substrates without using any photocatalyst. Moreover, a wide substrate scope demonstrated good synthetic versatility and practicality.

Journal of Organic Chemistry published new progress about Aromatic compounds Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, HPLC of Formula: 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tang, Bo published the artcileHierarchical FAU-Type Hafnosilicate Zeolite as a Robust Lewis Acid Catalyst for Catalytic Transfer Hydrogenation, Related Products of esters-buliding-blocks, the main research area is hafnosilicate zeolite catalyst transfer hydrogenation.

FAU-type hafnosilicate zeolite with a hierarchical structure (Hf-USY) was constructed through a post-synthesis strategy containing the controlled dealumination of the com. H-USY zeolite and the subsequent dry impregnation of the Cp2HfCl2 precursor. The incorporation of Hf ions into the zeolite framework involved the interaction between the silanol groups from framework dealumination and Cp2HfCl2 mols. Characterization results from UV-vis and XPS verified that the incorporated Hf ions mainly existed in the tetrahedrally coordinated form in the zeolite framework. The creation of Lewis acid sites associated with Hf incorporation was confirmed by Fourier transform IR spectroscopy with pyridine and deuterated acetonitrile adsorption. The as-synthesized Hf-USY zeolite served as a highly efficient catalyst in the transfer hydrogenation of Et levulinate to γ-valerolactone, outperforming the Sn- and Zr-silicate analogs. The Hf-USY catalyst also exhibited good performance in the transfer hydrogenation of more challenging substrates such as furanic, aromatic, as well as alkene-substituted carbonyl compounds into the corresponding alcs. The influence of Lewis acid sites, preparation parameters, as well as the hydrogen donor on the catalytic activity of the Hf-USY zeolite was investigated in detail. FAU-type hafnosilicate zeolite with a hierarchical structure is developed as a robust catalyst for the transfer hydrogenation of Et levulinate to γ-valerolactone.

ACS Sustainable Chemistry & Engineering published new progress about Beta zeolites Role: CAT (Catalyst Use), USES (Uses) (dealluminated, Hf-). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Connatser, Raynella M. published the artcileApproaches to investigate the role of chelation in the corrosivity of biomass-derived oils, Synthetic Route of 539-88-8, the main research area is chelation investigate role corrosivity biomass derived oil.

The need to provide the U. S. market with a renewable liquid fuel energy source from a non-food feedstock stream has gained considerable traction due to benefits such as improved energy efficiency, reduced environmental impacts, and enhanced national security. Practical achievement of these goals via biomass and bio-waste utilization involves production of liquid intermediates containing corrosive, reactive species like carboxylic acids, ketones, aldehydes, and hydroxyaldehydes. Such mixtures challenge materials of containment, processing, and transport. It is widely recognized that the smaller organic acids, such as acetic and formic, are corrosive and can remove protective surface oxides on alloys used in bio-oil processing infrastructure, and ketones can swell sealing polymers. However, literature shows, and findings herein confirm, larger carboxylic acids and bidentate alcs. are present. This highlights the potential for synergistic, detrimental effects of constituents in bio-oil corrosion, including direct reactivity of small acids compounded with the possibility of mobilization of protective metal oxide layers via chelation by larger acids and oxygenates. The question of whether species beyond small acids can significantly contribute to corrosion requires anal. approaches previously not applied to bio-oil corrosion studies and certainly not previously applied corroboratively. This work introduces a combination of optical, mass spectral, and electrochem. impedance spectroscopies with an incubation approach to study metal mobilization, to facilitate elucidating chelation’s role in bio-oil corrosive pathways. To enable systematic study of these oxygenates’ material compatibility individually and in combination, a model matrix of bio-oil constituents was also developed based on identification of key components of real bio-oils.

Biomass and Bioenergy published new progress about Aldehydes Role: TEM (Technical or Engineered Material Use), USES (Uses). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Synthetic Route of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Onkarappa, Sharath Bandibairanahalli published the artcileEfficient and Scalable Production of Alkyl Levulinates from Cellulose-Derived Levulinic Acid Using Heteropolyacid Catalysts, Related Products of esters-buliding-blocks, the main research area is levulinic acid heteropolyacid catalyst esterification alkyl levulinate preparation.

This work reports a straightforward and scalable synthesis of a series of alkyl levulinates from cellulose-derived levulinic acid and alkyl alcs. using com. available heteropolyacid catalysts under homegenous conditions. The reaction was optimized on parameters such as temperature, molar ratio of reagents, type and loading of catalyst. The solvent-free reactions afforded alkyl levulinates in high isolated yields (>85%) using only slight excess of alcs. and 10 wt% of catalyst at 120 °C in 6 h. Further, the catalysts were successfully recycled for three consecutive cycles without significant loss in activity.

ChemistrySelect published new progress about Aliphatic esters Role: IMF (Industrial Manufacture), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kurisingal, Jintu Francis published the artcileWater-Tolerant DUT-Series Metal-Organic Frameworks: A Theoretical-Experimental Study for the Chemical Fixation of CO2 and Catalytic Transfer Hydrogenation of Ethyl Levulinate to γ-Valerolactone, HPLC of Formula: 539-88-8, the main research area is zirconium hafnium naphthalenedicarboxylate Dresden University MOF preparation catalyst; water tolerant DUT MOF preparation fixation carbon dioxide catalysis; transfer hydrogenation MOF catalyzed ethyl levulinate gamma valerolactone preparation; cycloaddition carbon dioxide epoxide zirconium hafnium naphthalenedicarboxylate MOF catalyzed; CO2; DUT; biomass; cyclic carbonate; γ-valerolactone.

A series of highly thermally and hydrolytically stable porous solids with intriguing properties of zirconium- and hafnium-based metal-organic frameworks (MOFs) [Dresden University of Technol. (DUT) series] was synthesized. The DUT MOFs were effective catalysts for both epoxide-CO2 cycloaddition reactions and the catalytic transfer hydrogenation (CTH) of Et levulinate (EL). In particular, 12-connected DUT-52(Zr) showed higher catalytic activity than eight- and six-connected catalysts in the synthesis of cyclic carbonates as well as in the production of γ-valerolactone (GVL). The secondary building unit connectivity, coexistence of a moderate number of acidic and basic sites, Brunauer-Emmett-Teller surface area, and combined effects of the pores of the MOFs seem to influence the catalytic activity. The reaction mechanism for the DUT-52(Zr)-mediated cycloaddition reaction of CO2 and the CTH reactions were investigated in detail by using periodic d. functional theory calculations To the best of authors knowledge, this is the first detailed computational study for the formation of GVL from EL by using MOF as the catalyst. In addition, grand canonical Monte Carlo simulations predicted the strong interaction of CO2 mols. with the DUT-52(Zr) framework. Remarkably, the DUT-series catalysts possess extraordinary tolerance toward water. Further, DUT-52(Zr) is recyclable and is an efficient catalyst for cycloaddition and CTH reactions for at least five uses without obvious reductions in the activity or structural integrity.

ACS Applied Materials & Interfaces published new progress about Cyclic carbonates Role: SPN (Synthetic Preparation), PREP (Preparation). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, HPLC of Formula: 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jiang, Haiwei published the artcileHydrothermal liquefaction of Cd-enriched Amaranthus hypochondriacus L. in ethanol-water co-solvent: Focus on low-N bio-oil and heavy metal/metal-like distribution, Product Details of C7H12O3, the main research area is hydrothermal liquefaction cadmium amaranthus hypochondriacus; ethanol water nitrogen bio oil heavy metal.

The high nitrogen content in bio-oil from protein-rich biomass will cause the possible pollution problems by NOX emissions during combustion. In this study, Cd-enriched Amaranthus hypochondriacus L. (AHL) was treated by hydrothermal liquefaction (HTL) in ethanol-water co-solvent aiming to reduce the nitrogen content of the bio-oil. Besides, aqueous phase recycling (APR) was applied to achieve a higher bio-oil yield. HTL in ethanol-water co-solvent with APR three times resulted in the maximum bio-oil yield (47.26%) and greatly reduced the nitrogenous compounds content of bio-oil. During the APR process, the increase of total nitrogen (TN) content in the aqueous phase indicated that organic-N in the organic phase transformed into NH+4 to the aqueous phase. Acetic acid (13.87-22.37 mg/mL) was dominated in the aqueous phase, leading to a low pH value (6.27-5.29), which could serve as the possible catalyst for the HTL process during APR that can be the reason for the higher bio-oil yield. After the HTL process, Cr, Cu, Cd and Pb remained mostly in bio-char while As was present largely in the aqueous phase. Thus, this study demonstrated that the APR for HTL process in ethanol-water co-solvent can be a hopeful method to dispose the high-protein biomass for improved bio-oil yield and quality.

Fuel published new progress about Alcohols Role: TEM (Technical or Engineered Material Use), USES (Uses). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Product Details of C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vilanculo, Castelo Bandane published the artcileH4SiW12O40-Catalyzed Levulinic Acid Esterification at Room Temperature for Production of Fuel Bioadditives, Application of Ethyl 4-oxopentanoate, the main research area is levulinic acid esterification silicotungstic acid catalyst fuel bioadditive.

In this work, a route to synthesize bioadditives through H4SiW12O40-catalyzed levulinic acid esterification reactions with alcs. of short chain at room temperature was assessed. Among the Bronsted acids assessed (i.e., sulfuric, p-toluenesulfonic, silicotungstic, phosphomolybdic and phosphotungstic acids), H4SiW12O40 was the most active and selective catalyst. High conversions (ca. 90%) and selectivity (90-97%) for alkyl levulinates with carbon chain size ranging from C6 to C10 were obtained. The effect of main reaction parameters was studied, with a special focus on the reaction temperature, stoichiometry of reactants, concentration and nature of the catalyst. Insights on reaction mechanism were done and the activity of heteropoly catalysts was discussed based on acid strength and softness of the heteropolyanions. The use of renewable raw material, the mild reaction conditions (i.e., room temperature), and a recyclable solid catalyst are the some of the pos. features of this process. The alkyl levulinates obtained are renewable origin bioadditives that can be blended either to gasoline or diesel.

Waste and Biomass Valorization published new progress about Bronsted acids Role: CAT (Catalyst Use), PRP (Properties), USES (Uses). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Application of Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hess, Stefan published the artcileApproach to the Core Structure of Streptosetin A, Computed Properties of 539-88-8, the main research area is streptosetin A core synthesis.

Streptosetin A (I) belongs to the 3-decalinoyltetramic acids. In contrast to most of other known natural products of this type, the decalin part features a β-hydroxyketone subunit, making an intramol. cycloaddition approach less suitable. We examined an approach where the decalin part would be fashioned by an intramol. aldol addition By using a Diels-Alder reaction between the Rawal diene and a substituted methacrylate, a cyclohexanone was obtained. An organocuprate addition introduced the Et substituent before, the side chain was converted to an enal. However, contrary to our expectations, the aldol reaction led to the condensation product. Other routes to reach the key cyclohexanone were also investigated.

ChemistrySelect published new progress about streptosetin A core synthesis. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Computed Properties of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics