Category: 5340-78-3

Oehme, Guenther published the artcileTheory of α-keto acids. XVI. Infrared and dipole moment measurements for study of the steric effect of alkyl radicals in the β-position on the conformation of ethyl α-bromo-carboxylates and ethyl α-ketocarboxylates, Name: Ethyltert-butylacetate, the publication is Chemische Berichte (1968), 101(4), 1499-509, database is CAplus.

The dipole moments and ir spectra of the title compounds, RCHBrCO2Et (I) and RCOCO2Et (II), were dependent on the size of the alkyl R group. In the series R = Me, Et, iso-Pr, tert-Bu, a discontinuity, attributed to conformational differences between halo and ester or α-carbonyl and ester groups, was observed in going from iso-Pr to tert-Bu. Among the I, only I (R = tert-Bu) was present in rotational isomer form, while for the II, coexisting conformational isomers were generally detected.

Chemische Berichte published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Name: Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pike, Ryan A. S. published the artcileK₂CO₃-Catalyzed Synthesis of 2,5-Dialkyl-4,6,7-tricyano-Decorated Indoles via Carbon-Carbon Bond Cleavage, SDS of cas: 5340-78-3, the publication is Organic Letters (2020), 22(8), 3268-3272, database is CAplus and MEDLINE.

A novel method to synthesize 2,5-dialkyl-4,6,7-tricyanoindole derivatives from a base-catalyzed reaction of 1,3-diketones with fumaronitrile was described. The reaction proceeded by the condensation of two mols. of fumaronitrile and one mol. of 1,3-diketone in a remarkable process that involved the cleavage of one C(sp³)-C(sp²) bond in 1,3-diketones and the formation of one carbon-nitrogen bond and four carbon-carbon bonds to construct both the aryl and pyrrole rings of the indole in one step.

Organic Letters published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, SDS of cas: 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Julia, Marc published the artcileOxidation of carbanions with lithium tert-butyl peroxide, Name: Ethyltert-butylacetate, the publication is Synlett (1993), 233-4, database is CAplus.

Lithium tert-Bu peroxide reacts with several carbanions, leading to the corresponding alcs. via oxygen transfer. Lithiated arenes can be converted into phenols. An easy and convenient preparation of ynolates opening the way to ketenes, esters or silyl ynol ethers from acetylides is reported. Lithiated hydroperoxides display an electrophilic behavior at oxygen that can be compared with the electrophilic properties of carbenoids.

Synlett published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Name: Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guo, Qihang published the artcileControllable Intramolecular Unactivated C(sp3)-H Amination and Oxygenation of Carbamates, Category: esters-buliding-blocks, the publication is Organic Letters (2019), 21(4), 880-884, database is CAplus and MEDLINE.

Dual catalyst-controlled intramol. unactivated C(sp³)-H amination and oxygenation of carbamates merging visible-light photocatalysis and earth-abundant transition metal catalysis have been reported. Useful amino alc. and diol derivatives could be selectively obtained from readily available tertiary alc. derivatives The possible mechanisms have been proposed via a 1,5-HAT process followed by Lewis acid-controlled cyclization. The nickel and zinc catalysts inhibit the formation of oxygenation and amination products, resp. An interesting phenomenon of chirality transfer is also observed

Organic Letters published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Galamb, V. published the artcileAlkylcobalt tetracarbonyls. V. Reaction of α-substituted α-haloacetic acid esters with sodium tetracarbonylcobaltate, Category: esters-buliding-blocks, the publication is Acta Chimica Academiae Scientiarum Hungaricae (1982), 111(2), 131-9, database is CAplus.

Treating Na[Co(CO)₄] with halo esters BrCHRCO₂R¹ (R = Me, Me₃C, Ph; R¹ = Me, Et) gave alkylcobalt tetracarbonyls RCH(CO₂R¹)Co(CO)₄, some of which were isolated. In the case of PhCHBrCO₂Et, the π-benzyl cobalt complex I was also obtained. Decomposition of the reaction mixtures yielded hydrogenated and carbonylated derivatives, along with coupling products of the starting compounds The decomposition involves radical reaction pathways. Treating Na[Co(CO)₄] with di-Et bromomalonate gave, after the usual workup, mainly the hydrogenolysis product di-Et malonate.

Acta Chimica Academiae Scientiarum Hungaricae published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Fuentes, M. Angeles published the artcileCatalytic Functionalization of Methane and Light Alkanes in Supercritical Carbon Dioxide, Application of Ethyltert-butylacetate, the publication is Chemistry – A European Journal (2014), 20(35), 11013-11018, database is CAplus and MEDLINE.

The development of catalytic methods for the effective functionalization of methane yet remains a challenge. The best system known to date is the so-called Catalytica Process based on the use of platinum catalysts to convert methane into Me bisulfate with a TOF rate of 10^-3 s. In this contribution, the authors report a series of silver complexes containing perfluorinated tris(indazolyl)borate ligands that catalyze the functionalization of methane into Et propionate upon reaction with Et diazoacetate (EDA) by using supercritical carbon dioxide (scCO₂) as the reaction medium. The employment of this reaction medium has also allowed the functionalization of ethane, propane, butane and isobutane. The synthesis of the target compounds was achieved using silver-boron-indazole derivatives as catalysts, such as [hydrotris[4,5,6,7-tetrafluoro-3-(trifluoromethyl)-1H-indazolato-κN¹]borato(1-)-κN²,κN^2′,κN^2”](2-propanone)silver, [hydrotris[4,5,6,7-tetrafluoro-3-(1,1,2,2,2-pentafluoroethyl)-1H-indazolato-κN¹]borato(1-)-κN²,κN^2′,κN^2”](tetrahydrofuran)silver. The tilte compounds thus formed included propanoic acid Et ester, butanoic acid Et ester, 3-ethylpentanoic acid Et ester, 3-methylhexanoic acid Et ester, heptanoic acid Et ester, pentanoic acid Et ester, 3-methylbutanoic acid Et ester, 4-methylpentanoic acid Et ester, hexanoic acid Et ester, 3-methylpentanoic acid Et ester.

Chemistry – A European Journal published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Application of Ethyltert-butylacetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Takeuchi, Seiji published the artcileEnantioselective protonation of samarium enolates by a C₂-symmetric chiral diol, HPLC of Formula: 5340-78-3, the publication is Tetrahedron: Asymmetry (1994), 5(9), 1763-80, database is CAplus.

High enantioselectivity (up to 97% ee) has been achieved in the protonation of samarium enolates which were generated by SmI₂-mediated cross-coupling reaction between unsym. dialkylketenes and allyl iodide, using C₂-sym. chiral diol (S,S)-o-C₆H₄(CH₂OCH₂CHPhOH)₂ as a proton source. The stereochem. of enolate formation and of the enantioselective protonation is discussed.

Tetrahedron: Asymmetry published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C12H9N3O4, HPLC of Formula: 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Eberson, Lennart published the artcileElectron transfer reactions in organic chemistry. XXIII. Products, kinetics and inverted spin trapping in the reaction between carboxylates and hexachloroosmate(V) ion, Application In Synthesis of 5340-78-3, the publication is Acta Chemica Scandinavica (1993), 47(11), 1129-37, database is CAplus.

The reaction between carboxylates and hexachloroosmate(V) has been investigated. For carboxylates, RCOO^–, corresponding to radicals R^• which are difficult to oxidize (with E_i larger than ∼9 eV), the reaction gave one-electron oxidation products, as typified by the formation of C-to-N coupling products in good yield from tert-butylcyanoacetate ion. The kinetics of the reaction between the hydrogendiacetate ion and OsCl₆^– in acetonitrile was studied in more detail and found to conform to a kinetic model involving a second-order electron-transfer step between acetate ion (existing in equilibrium with acetic acid and hydrogen-diacetate ion) and OsCl₆^–. Attempts to trap R^• from the carboxylate/hexachloroosmate reaction by α-phenyl-N-tert-butylnitrone (PBN) led only to the formation of acyloxyl spin adducts, presumably via the reaction between PBN^•+ (formed by one-electron oxidation of PBN by the osmate) and the carboxylate ion. Other nucleophiles underwent the same type of reaction, previously denoted inverted spin trapping, and also the more oxidation-resistant spin trap 4-NO₂BPN was shown to possess this type of reactivity.

Acta Chemica Scandinavica published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Application In Synthesis of 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lazewska, Dorota published the artcileAlkyl derivatives of 1,3,5-triazine as histamine H₄ receptor ligands, Category: esters-buliding-blocks, the publication is Bioorganic & Medicinal Chemistry (2019), 27(7), 1254-1262, database is CAplus and MEDLINE.

This study focuses on the design, synthesis, mol. modeling and biol. evaluation of a novel group of alkyl-1,3,5-triazinyl-methylpiperazines. New compounds were synthesized and their affinities for human histamine H₄ receptor (hH₄R) were evaluated. Among them, 4-(cyclohexylmethyl)-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine (14) exhibited hH₄R affinity with a K_i of 160 nM and behaved as antagonist in functional assays: the cellular aequorin-based assay (IC₅₀ = 32 nM) and [³⁵S]GTPγS binding assay (pK_b = 6.67). In addition, antinociceptive activity of 14 in vivo was observed in Formalin test (in mice) and in Carrageenan-induced acute inflammation test (in rats).

Bioorganic & Medicinal Chemistry published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Roberts, David C. published the artcileAcetoacetic ester condensation. XI. The extent of the condensation of certain monosubstituted acetic esters, HPLC of Formula: 5340-78-3, the publication is Journal of the American Chemical Society (1937), 2007-8, database is CAplus.

cf. C. A. 29, 6212.5. With 0.4 mol. EtONa and 2.4 mols. of ester, the following yields of RCH₂COCHRCO₂Et were obtained (at 95° except for R = H (78°)): R = H, 75-6% (based on EtONa); Me, 46-7; Et, 40-2; Pr, 34-35; Me₂CH and Me₃C, 0; Ph 53-5. Thus, the substitution of a normal alkyl group for one of the Me-H atoms of AcOEt progressively lowered the extent of the condensation as the size of the alkyl group increased. Sec. and tert substituents completely prevented the condensation, even under conditions that would allow the reaction to proceed to completion. PhCH₂CO₂Et condensed to a less extent than did AcOEt but to a considerably greater extent than did any of alkyl-substituted esters.

Journal of the American Chemical Society published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, HPLC of Formula: 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics