Application of 52449-43-1, The chemical industry reduces the impact on the environment during synthesis 52449-43-1, name is Methyl 4-chlorophenylacetate, I believe this compound will play a more active role in future production and life.
Example 1 Preparation of Methyl 2-bromo-(4-Chlorophenyl)acetate 116 g (0.585 mol) of 1,3-dibromo-5,5-dimethylhyntantoin [sic] and 1 g of AIBN were added portionwise to the solution of 215.3 g (1.17 mol) of methyl 4-chlorophenylacetate in 500 ml of tetrachloromethane, and the mixture was refluxed for 24 hours. This was followed by washing with water and 1 N sodium hydroxide solution, the aqueous phases were extracted with methylene chloride, and the organic phases were dried and concentrated. This gave 260 g of the title compound. 1H NMR [delta, (CDCl3)]: 3.8 (s, 3H); 5.3 (s, 1H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 4-chlorophenylacetate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Grammenos, Wassilios; Sauter, Hubert; Cullmann, Oliver; Gewehr, Markus; Muller, Bernd; Blasco, Jordi Tormo i; Gotz, Norbert; Volk, Thorsten; Lorenz, Gisela; Ammermann, Eberhard; Stierl, Reinhard; Strathman, Siegfried; US2003/191190; (2003); A1;,
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