Category: 52273-79-7

Adding a certain compound to certain chemical reactions, such as: 52273-79-7, name is Ethyl 2-(3-aminophenyl)acetate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 52273-79-7, COA of Formula: C10H13NO2

Ethyl 3-{3-[N-(3-methoxyphenyl)-N-(N-methyl-N-phenylcarbamoylmethyl)carbamoylmethyl]ureido}phenylacetate may be prepared in a manner similar to that described in Example 26 for the preparation of ethyl 3-{3-[N-(3-methoxyphenyl)-N-(N-methyl-N-phenylcarbamoylmethyl)carbamoylmethyl]ureido}benzoate, but starting with 2-[N-(3-methoxyphenyl)isocyanatoacetamido]-N-methyl-N-phenylacetamide (2.4 g) and ethyl 3-aminophenylacetate (1.1 g). The crude product is purified by chromatography on silica (0.063-0.2 mm) (60 g) contained in a column 2.0 cm in diameter [eluent: dichloromethane/ethyl acetate (20:80 by volume)], collecting 20-cc fractions.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 2-(3-aminophenyl)acetate, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Rhone-Poulenc Rorer S.A.; US5475106; (1995); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Related Products of 52273-79-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 52273-79-7, name is Ethyl 2-(3-aminophenyl)acetate belongs to esters-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

EXAMPLE 6 N-(3-Ethoxycarbonylmethylphenyl)-L-glutamine: Compound (6) Following the procedure described in (a) of Example 1, 11.14 g (0.03 mole) of N-carbobenzoxy-L-glutamic acid alpha-benzyl ester was reacted with 4.96 g (0.03 mole) of ethyl m-aminophenylacetate to give 12.95 g (81% yield) of an intermediate. The intermediate was dissolved in 500 ml of tetrahydrofuran, 200 ml of ethanol and 100 ml of water. To the solution was added 0.3 g of palladium black and the mixture was subjected to hydrogenation at atmospheric pressure to give 6.58 g (89% yield) of N-(3-ethoxycarbonylmethylphenyl)-L-glutamine, m.p. 175.5-176.2 C. [alpha]D25 =+26.4 (c=1 2 N HCl)

The synthetic route of Ethyl 2-(3-aminophenyl)acetate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Mitsubishi Chemical Industries Ltd.; Nippon Shinyaku Co., Ltd.; US4439448; (1984); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 52273-79-7, name is Ethyl 2-(3-aminophenyl)acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Recommanded Product: Ethyl 2-(3-aminophenyl)acetate

General procedure: 4-bromobenzenesulfonyl chloride (3 g) and 3-aminobenzylalcohol (3 g) were stirred in dichloromethane (50 mL) containing pyridine (3 mL) for 3 h at room temperature. The mixture was poured into acidified water (HCl), and extracted with ethyl acetate (250 mL). The organic was washed with water and saturated NaCl solution, dried (Na2SO4), the solvent was evaporated and the desired product obtained as a white solid, washed with ether and recrystallised from ethyl acetate / petrol to give 4-bromo-N-(3-(hydroxymethyl)phenyl)benzenesulfonamide as white crystals.

The synthetic route of Ethyl 2-(3-aminophenyl)acetate has been constantly updated, and we look forward to future research findings.

Reference:
Article; Greig, Iain R.; Coste, Emmanuel; Ralston, Stuart H.; Van ‘T Hof, Robert J.; Bioorganic and Medicinal Chemistry Letters; vol. 23; 3; (2013); p. 816 – 820;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

These common heterocyclic compound, 52273-79-7, name is Ethyl 2-(3-aminophenyl)acetate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Formula: C10H13NO2

(3-Amino-phenyl)-acetic acid ethyl ester (0.895 g, 5.0 mmol) and acetyl chloride (0.26 mL, 5.0 mmol) are added to a round bottomed flask containing THF (20 mL), pyridine (0.60 mL) and DMAP (10 mg). The mixture is stirred at room temperature overnight. The clear solution is diluted with EtOAc (200 mL), washed with 1N HCl (3¡Á100 mL) and brine (100 mL), and dried with MgSO4. Solvent is evaporated in vacuo to afford intermediate 14-B as a white solid that is used without further purification

The synthetic route of Ethyl 2-(3-aminophenyl)acetate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; IRM LLC; US2007/276002; (2007); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics