Category: 5205-11-8

Green, Samantha A. published the artcileIron-Nickel Dual-Catalysis: A New Engine for Olefin Functionalization and the Formation of Quaternary Centers, Recommanded Product: 3-Methylbut-2-en-1-yl benzoate, the publication is Journal of the American Chemical Society (2018), 140(36), 11317-11324, database is CAplus and MEDLINE.

Alkene hydroarylation forms carbon-carbon bonds between two foundational building blocks of organic chem.: olefins and aromatic rings. In the absence of electronic bias or directing groups, only the Friedel-Crafts reaction allows arenes to engage alkenes with Markovnikov selectivity to generate quaternary carbons. However, the intermediacy of carbocations precludes the use of electron-deficient arenes, including Lewis basic heterocycles. Here we report a highly Markovnikov-selective, dual-catalytic olefin hydroarylation that tolerates arenes and heteroarenes of any electronic character. Hydrogen atom transfer controls the formation of branched products and arene halogenation specifies attachment points on the aromatic ring. Mono-, di-, tri-, and tetra-substituted alkenes yield Markovnikov products including quaternary carbons within nonstrained rings.

Journal of the American Chemical Society published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Recommanded Product: 3-Methylbut-2-en-1-yl benzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ryabchenko, Boris published the artcileInvestigation of anticancer and antiviral properties of selected aroma samples, Quality Control of 5205-11-8, the publication is Natural Product Communications (2008), 3(7), 1085-1088, database is CAplus.

Antitumor and antiviral activities of various aroma samples, including cinnamic acid, β-caryophyllene, caryophyllene oxide, nerolidol (synthetic and natural samples), trans,trans-farnesol, farnesol (isomeric mixture), longifolene, geranic acid and a farnesol-rich ylang-fraction were investigated using HeLa and Jurkat cell lines. Using a CytoTox-96-Assay we observed strong antitumor effects of natural- and synthetic nerolidol-samples at concentrations less than 5 μM. Furthermore, synthetic nerolidol reduced the number of HeLa and Jurkat cells to 50% (CC₅₀) at concentrations which were more than ten times lower compared with the EDs required to achieve 50% cytotoxicity (ED₅₀). Antiviral studies were performed to investigate inhibitory effects of the compounds on mouse polyomavirus propagation in 3T6 cells. Remarkable inhibition of viral activity was demonstrated by synthetic nerolidol at CC₅₀ 3.2±1.5 μM and natural nerolidol at CC₅₀ 1.2±0.4 μM All other compounds, however, did not show any inhibition against this virus.

Natural Product Communications published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Quality Control of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Joichi, Atsushi published the artcileSedative aroma constituents in orchid flowers II: the scent of Cattleya, Category: esters-buliding-blocks, the publication is Aroma Research (2010), 11(3), 256-264, database is CAplus.

Cattleya, an orchid, attracts many people in the world, and most of Cattleya species emit pleasant perfumes. We analyzed the volatile components of 17 kinds of Cattleya species flowers by using a head space GC-MS. We newly found 1,3-dimethoxy-5-Me benzene (DMMB) in the volatile component of C. schroderae and 1,4-dimethoxy benzene (DMB) in C. intermedia. It was already reported that DMMB and DMB showed sedative effect on a consciousness level and promoted the recovery of skin barrier function on human beings. We also found Et 4-methoxy benzoate (E4MB) in the volatile component of C. percivaliana, and E4MB showed sedative effect on human sympathetic nervous activity.

Aroma Research published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yamada, Tohru published the artcileDirect epoxidation of olefins catalyzed by nickel(II) complexes with molecular oxygen and aldehydes, Application In Synthesis of 5205-11-8, the publication is Bulletin of the Chemical Society of Japan (1991), 64(7), 2109-17, database is CAplus.

In the presence of a bis(1,3-diketonato)nickel(II) complex, various olefins are directly monooxygenated into the corresponding epoxides on treatment with atm. pressure of oxygen or air and aldehydes. Especially, it is noted that bis[1,3-bis(p-methoxyphenyl)-1,3-propanedionato]nickel(II) (I) behaves as an excellent catalyst in the present epoxidation Thus epoxidation of 2-methyl-2-decene in the presence of oxygen, isobutyraldehyde and catalyst I gave the epoxide II quant., at room temperature

Bulletin of the Chemical Society of Japan published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C14H19NO8, Application In Synthesis of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Okinczyc, Piotr published the artcileProfile of polyphenolic and essential oil composition of polish propolis, black poplar and aspens buds, Application In Synthesis of 5205-11-8, the publication is Molecules (2018), 23(6), 1262/1-1262/18, database is CAplus and MEDLINE.

In this work, we studied similarities and differences between 70% ethanol in water extract (70EE) and essential oils (EOs) obtained from propolis, black poplars (Populus nigra L.) and aspens (P. tremula L.) to ascertain which of these is a better indicator of the plant species used by bees to collect propolis precursors. Composition of 70EE was analyzed by UPLC-PDA-MS, while GC-MS was used to research the EOs. Principal component analyses (PCA) and calculations of Spearman’s coefficient rank were used for statistical anal. Statistical anal. exhibited correlation between chem. compositions of propolis and Populus buds’ 70EE. In the case of EOs, results were less clear. Compositions of black poplars, aspens EOs and propolises have shown more variability than 70EE. Different factors such as higher instability of EOs compared to 70EE, different degradation pattern of benzyl esters to benzoic acid, differences in plant metabolism and bees’ preferences may be responsible for these phenomena. Our research has therefore shown that 70EE of propolis reflected the composition of P. nigra or complex aspen-black poplar origin.

Molecules published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Application In Synthesis of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Isidorov, Valery A. published the artcileRapid GC/MS determination of botanical precursors of Eurasian propolis, Category: esters-buliding-blocks, the publication is Food Chemistry (2014), 101-106, database is CAplus and MEDLINE.

In this work, ether extracts of propolises from 11 countries of Europe and Asia together with extracts of the buds of their principal plant precursors were prepared and investigated by gas chromatog.-mass spectrometry. For the first time, chem. compositions of the exudates of aspen, white birch and silver birch buds were determined Basing on the data on the content of individual components and their groups, the method of rapid examination of plant precursors of propolis was developed. This new method is based on the use of a chromatogram for one extracted ion m/z = 219, characteristic for a group of similar substances: phenylpropenoids. The I^T retention indexes of silylated derivatives of 449 substances registered in the buds of 6 species of trees and 37 samples of propolis extracts were calculated These useful anal. parameters (majority of which are absent in the available databases) are attached in Supplementary information.

Food Chemistry published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Cui, Bin published the artcileMn(OAc)₃-Mediated Hydrotrifluoromethylation of Unactivated Alkenes Using CF₃SO₂Na as the Trifluoromethyl Source, Quality Control of 5205-11-8, the publication is Journal of Organic Chemistry (2018), 83(11), 6015-6024, database is CAplus and MEDLINE.

Unfunctionalized alkenes such as alkenyl ethers, amides, sulfonamides, and esters underwent regioselective hydrotrifluoromethylation with F₃CSO₂Na (Langlois’s reagent) mediated by Mn(OAc)₃ in AcOH at ambient temperature under Ar. TEMPO inhibited the hydrotrifluoromethylation (yielding TEMPO-CF₃), and hydrotrifluoromethylation of N,N-diallyl-p-toluenesulfonamide yielded a trifluoroethyl-substituted pyrrolidine, consistent with a radical mechanism for the hydrotrifluoromethylation reaction; deuteration experiments with O- and C-deuterated acetic acid were performed to determine the source of hydrogen atoms.

Journal of Organic Chemistry published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Quality Control of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Reddy, G. Sudhakar published the artcileNitrosyl Triflate and Nitrous Anhydride, Same Mode of Generation, but Very Different Reaction Pathways. Direct Synthesis of 1,2-Oxazetes, Nitroso or Bisoxazo Compounds from Olefins, Related Products of esters-buliding-blocks, the publication is Organic Letters (2022), 24(23), 4202-4206, database is CAplus and MEDLINE.

Nitrosyl triflate (TfONO) can be generated in situ from tetra-n-butylammonium nitrite and triflic anhydride (1:1) in CH₂Cl₂ solution at ca. -30°C. It acts as a powerful and soluble nitrosating agent with a wide range of olefinic or aromatic substrates. Nitrous anhydride (O=N-O-N=O) can be generated in the same way using tetra-n-butylammonium nitrite and triflic anhydride (2:1) in CH₂Cl₂ solution at ca. -30°C. Each reagent has been isolated and characterized. They react with olefins to give different products. Nitrosyl triflate is an excellent reagent for generating either vinylic or allylic nitroso compounds or their dimeric bisoxazo derivates. Nitrous anhydride efficiently converts many olefins to 1,2-oxazetes in a single step, making this class of compounds readily available from olefins for the first time. Authors have also discovered another route to 1,2-oxazetes involving a novel rearrangement/isomerization of allylic nitroso compounds which is catalyzed by Pd-C/H₂.

Organic Letters published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gajare, A. S. published the artcileNatural kaolinitic clay and EPZG: efficient solid catalysts for selective regeneration of carboxylic acids from their corresponding allyl or cinnamyl esters, COA of Formula: C12H14O2, the publication is Synthetic Communications (1998), 28(1), 25-33, database is CAplus.

Natural kaolinitic clay and EPZG are efficient catalysts for selective regeneration of carboxylic acids from their corresponding allyl or cinnamyl esters. E.g., BzOCH₂CH:CMe₂ gave 100% benzoic acid.

Synthetic Communications published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, COA of Formula: C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Li, Hongze published the artcileDirect Intermolecular Anti-Markovnikov Hydroazidation of Unactivated Olefins, Category: esters-buliding-blocks, the publication is Journal of the American Chemical Society, database is CAplus and MEDLINE.

We herein report a direct intermol. anti-Markovnikov hydroazidation method for unactivated olefins, which is promoted by a catalytic amount of bench-stable benziodoxole at ambient temperature This method facilitates previously difficult, direct addition of hydrazoic acid across a wide variety of unactivated olefins in both complex mols. and unfunctionalized commodity chems. It conveniently fills a synthetic chem. gap of existing olefin hydroazidation procedures, and thereby provides a valuable tool for azido-group labeling in organic synthesis and chem. biol. studies.

Journal of the American Chemical Society published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics