Category: 50670-76-3

Hattori, Hideshi published the artcileSynthesis and properties of photochromic liquid-crystalline polyacrylates containing a spirooxazine group, SDS of cas: 50670-76-3, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (1999), 37(17), 3513-3522, database is CAplus.

The novel photochromic liquid-crystalline polyacrylates containing a spirooxazine group were synthesized. The photochromic polymer containing (4-pentamethyleneoxy)biphenylene moiety at the 5-position of spironaphthoxazine showed nematic phase from 122.9 to 133.8°C. The photochromic polymer containing undecamethylene instead of pentamethylene showed smectic phase from 93.1 to 169.7°. On the other hand, the photochromic polymer containing both undecamethylene as a spacer and spironaphthoxazine-bound biphenylene moiety at 9′-position did not show any liquid crystallinity. All spirooxazine-containing liquid-crystalline polymers showed photochromism in the solid state at room temperature Because the shape of the absorption spectra of the photochromic quenched liquid-crystalline polymer films was almost the same as those of the photochromic amorphous polymer films, the photochromic properties did not depend on the mesophase in the polymers examined

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, SDS of cas: 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sahlen, F. published the artcileSynthesis and Characterization of Bifunctional Liquid-Crystalline Monomers Showing Smectic C Phase. Photopolymerization and Crosslinking, SDS of cas: 50670-76-3, the publication is Chemistry of Materials (1996), 8(2), 382-8, database is CAplus.

Novel syntheses of bifunctional liquid-crystalline acrylate and methacrylate monomers are described. Thermal and microstructural characterization of the monomers using small-angle X-ray scattering, differential scanning calorimetry, and optical microscopy revealed the presence of smectic A, smectic C, and smectic E phases. Photopolymerization of the bifunctional monomers conducted at different temperatures preserved the monomeric liquid-crystalline structure in the crosslinked polymers. The densely crosslinked polymers showed thermal reversibility. Mixtures of these monomers and chiral monofunctional liquid-crystalline monomers exhibited chiral smectic C mesomorphism that was made permanent by photopolymerization and subsequent crosslinking.

Chemistry of Materials published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, SDS of cas: 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tsukamoto, Takamasa published the artcileHighly Accurate Synthesis of Quasi-sub-nanoparticles by Dendron-assembled Supramolecular Templates, Formula: C15H14O3, the publication is Angewandte Chemie, International Edition (2022), 61(8), e202114353, database is CAplus and MEDLINE.

Quasi-sub-nanomaterials (1-3 nm) have been predicted to exhibit unique properties originating from the gray structures considered both bulk solids and mols., while their synthesis is extremely difficult. The present study describes a new template synthesis method for quasi-sub-nanosized materials using a combination of coordination chem. and polymer chem. Utilizing self-assembly of guest basic phenylazomethine dendron units onto host acidic core units with six tritylium cations, the dendron-assembled supramols. were constructed easily and quant. without costly techniques. This huge supramol. capsule accumulating multiple acidic rhodium salts in its basic ligands enabled a precise synthesis of rhodium particles via formation of multinuclear complexes. The obtained particles (Rh₈₄, â‰?.5 nm) have particle sizes within 1-3 nm range and were larger than conventional sub-nanoparticles (Rh₁₄, âˆ?.85 nm), therefore the precise template synthesis of quasi-sub-nanoparticles was successfully demonstrated.

Angewandte Chemie, International Edition published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C12H6NNaO4, Formula: C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Jeong, Hyeon Su published the artcileSpontaneous chirality induction and enantiomer separation in liquid crystals composed of achiral rod-shaped 4-arylbenzoate esters, Recommanded Product: Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, the publication is Journal of the American Chemical Society (2009), 131(41), 15055-15060, database is CAplus and MEDLINE.

The discovery of spontaneously induced chirality and enantiomeric separation in liquid crystal and soft crystal systems composed of achiral rod-shaped 4-arylbenzoate esters is described. Negligibly small CD signals are produced in the smectic A phases of these substances, and the signals were found to increase with increasing smectic order. Since the advent of chirality occurs in freely suspended films, it is not a consequence of surface effects. Both pos. and neg. CD signals are observed with equal probability at different positions in these films. Vibrational CD spectroscopy and theor. calculations are used to analyze the conformational changes that are associated with the induced chirality of the rod-shaped mols. The results show that the phenomenon is caused by the twisting of biphenyl bond associated with the ester moiety in 4-arylbenzoate esters.

Journal of the American Chemical Society published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Recommanded Product: Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Lei published the artcileUnusual microporous polycatenane-like metal-organic frameworks for the luminescent sensing of Ln³⁺ cations and rapid adsorption of iodine, Product Details of C15H14O3, the publication is Chemical Communications (Cambridge, United Kingdom) (2012), 48(47), 5919-5921, database is CAplus and MEDLINE.

Two isostructural 2-dimensional 2-dimensional parallel 3-dimensional inclined interpenetrating polycatenane-like metal-organic frameworks, [Zn₂L¹(H₂O)](NO₃)·DMF (IFMC-10) and [Zn₂L²(H₂O)](NO₃)·0.2DMF (IFMC-11) (H₃L¹ = 4′,4”,4”’-(2,4,6-trimethylbenzene-1,3,5-triyl)tris(methyleneoxy)tribiphenyl-4-carboxylic acid, I) and (H₃L² = 4′,4”,4”’-(2,4,6-trimethylbenzene-1,3,5-triyl) II) were successfully constructed based on length-adjusted tricarboxylate ligands. With the merit of being microporous, IFMC-10 can serve as host for encapsulating lanthanide cations (Eu³⁺, Sm³⁺ and/or Tb³⁺) to exhibit luminescent sensing and rapid adsorption of iodine.

Chemical Communications (Cambridge, United Kingdom) published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Product Details of C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kihara, Hideyuki published the artcileIn situ photochemical conversion from cinnamoyl-functionalized liquid-crystalline monomers to liquid-crystalline dimers, Related Products of esters-buliding-blocks, the publication is Liquid Crystals (2007), 34(11), 1337-1347, database is CAplus.

Liquid-crystalline (LC) monomers, which were functionalized with a cinnamoyl group on their extremity, were synthesized and irradiated with UV light in their LC phases. In the presence of a triplet sensitizer, most LC monomers were converted into the corresponding dimers, which were produced by the cycloaddition reaction of the cinnamoyl group. The photodimerization reaction could proceed while the LC phases were maintained, because the dimers showed LC phases whose temperature ranges were wider than those of the corresponding monomers. A ¹H NMR study of the LC dimers indicated that the cyclobutane unit dominantly had an anti-head-to-head configuration, i.e., δ-truxinate. As the LC monomers, which had a Ph biphenyl-4-carboxylate moiety as a mesogen, showed smectic A phases and the corresponding dimers also exhibited smectic A phases, the authors estimated the smectic layer distances by x-ray diffraction anal. and found that the dimers adopted the structure in which the two mesogens aligned laterally and existed in the same smectic layer in the LC phases.

Liquid Crystals published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kishikawa, Keiki published the artcileSimple and Efficient Chiral Dopants to Induce Blue Phases and Their Optical Purity Effects on the Physical Properties of Blue Phases, Safety of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, the publication is Journal of Physical Chemistry B (2014), 118(34), 10319-10332, database is CAplus and MEDLINE.

Blue phases (BPs) have received considerable attention as light shutters in the next generation of liquid crystal (LC) displays. However, no simple and efficient chiral dopant for induction of BPs of com. available rodlike LC compounds has been reported. In this study, both (R) and (S) forms of novel chiral dopants were synthesized, showed extremely high helical twisting power values in nematic LC compounds, and induced stable BPs with a small amount of our chiral dopants (3-5 mol %). In enantiomeric excess controlled experiments, we found novel phenomena in their phys. properties, such as generation of a metastable chiral nematic phase between an isotropic state and a BP.

Journal of Physical Chemistry B published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Safety of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wilds, A. L. published the artcileSteroid analogs lacking ring C. II. Some analogs of progesterone and desoxycorticosterone, Safety of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, the publication is Journal of the American Chemical Society (1950), 2388-95, database is CAplus.

cf. C.A. 44, 1086c; 45, 140g. Procedures were developed for the synthesis of some analogs of progesterone (I) and desoxycorticosterone lacking ring C and with a 6-membered ring D. The method involved the Robinson-Mannich base procedure for synthesizing α,β-unsaturated cyclic ketones, modified for application to hydroxymethylene ketones. The I analogs were physiologically inactive. p-MeOC₆H₄Ph, obtained in 95-7% yield from p-HOC₆H₄Ph and Me₂SO₄, was converted to p-(p-MeOC₆H₄)C₆H₄COMe (II), m. 155-6°, in 56% yield (cf. C.A. 40, 7172.1). Oxidation of 174 g. II with NaOBr and demethylation of the resulting 176 g. crude MeO acid with 460 ml. 48% HBr and 2200 ml. AcOH by refluxing 14 hrs. with exclusion of air gave 95% 4′-hydroxy-4-biphenylcarboxylic acid (III), m. 292-4° after sublimation and recrystallization from AcOH. The Me ester of III, colorless cubes, m. 227-8° (from Me₂CO), was obtained in 92-5% yield by refluxing III 2 hrs. with MeOH saturated at 50° with HCl gas. The Et ester, m. 142-3° (from Me₂CO-CCl₄), was similarly prepared in 87% yield after refluxing 24 hrs. A suspension of 40 g. Me ester in 85 ml. absolute MeOH was hydrogenated 12 hrs. with 10 g. W-6 Raney Ni at 85° and an initial H pressure of 4500 lb./sq. in., the catalyst filtered off, and washed with MeOH (500 ml. total MeOH), 50 ml. 45% KOH added, the solution refluxed 2 hrs., diluted with 2 l. H₂O, extracted with 3 portions of CHCl₃, and the extract evaporated, giving 8.5 g. semisolid neutral material. The alk. solution was acidified, extracted with 3 portions of CHCl₃, the extract dried over Na₂SO₄, and the solvent removed, leaving 28.0 g. (70%) of a mixture of acids. Recrystallization from Me₂CO gave 1 of the stereoisomers of 4-(4-carboxycyclohexyl)cyclohexanol (IV), colorless prisms, m. 194-5°. Attempts to sep. the mixture of acids by fractional acidification of their Na₂CO₃ solution failed, yielding a mixture m. 115-205°. When the reduced ester mixture was not hydrolyzed but crystallized from Et₂O-petr. ether, recrystallization from CCl₄ of the solid (18%, m. 90-5°) gave 1 of the isomeric Me esters of IV, m. 98-100°, hydrolyzed by alkali to the same stereoisomer, m. 194-5°, of IV as above. The crude mixture of isomers of IV (28 g.) was dissolved in 500 ml. AcOH, cooled to 16°, stirred with 23 g. Cr₂O₃ in 20 ml. H₂O, 50 ml. AcOH slowly added over 1 hr., the mixture kept at 16-20° 1 addnl. hr., then treated with 25 ml. MeOH, poured into 2 l. H₂O containing 50 ml. HCl, the mixture extracted several times with CHCl₃, the extract washed with dilute HCl and H₂O, dried over Na₂SO₄, the solvent removed, and the residue recrystallized from Me₂CO, giving in 2 crops 8.7 g. (31%) of a crude isomer A of 4-(4-carboxycyclohexyl)cyclohexanone (V), m. 174-5°. From the filtrate, by crystallization from petr. ether-Et₂O, was obtained 14.1 g. (50%) of a mixture (m. 84-90°), largely a 2nd isomer B of V. The Me ester of isomer A, obtained in 99% yield with CH₂N₂ in Et₂O, from petr. ether, colorless prisms, m. 39-40° (2,4-dinitrophenylhydrazone, prepared in 57% yield in MeOH containing a trace of HCl, from AcOMe, orange prisms, m. 197-8°). Partial purification of the crude isomer B of V by fractional acidification of its solution in Na₂CO₃ or adsorption of the Me ester on alumina and fractional elution, resulting in each case in concentration of isomer B in the 1st fraction. The best method was to remove as much of isomer A as possible, then seed a solution in C₆H₆ with pure isomer B, and cool, giving a product m. 96-6.5° (from C₆H₆ and Et₂O-petr. ether). The solid isomer m. 194-5°, of IV, oxidized with Cr₂O₃, gave isomer B, m. 96-6.5°, of V. The Me ester was an oil, yielding 55% 2,4-dinitrophenylhydrazone, orange needles, m. 107-9° (from MeOH), resolidifying, and m. 131-2°. A suspension of 5 g. Et ester of III was hydrogenated 30 min. with 2 g. W-6 Raney Ni at a pressure of 2400 lb./sq.in. and 110°, the catalyst and solvent removed, and the residue dissolved in Et₂O and extracted with 3 portions of cold 5% KOH; from the Et₂O was obtained 3.80 g. oil which partially solidified, and on recrystallization from Et₂O-petr. ether gave one isomer of the Et ester of 4-(p-carboxyphenyl)cyclohexanol (VI), fine colorless needles, m. 134-5°. The remainder of the neutral product was hydrolyzed by refluxing 2 hrs. with 60 ml. MeOH and 10 ml. 45% KOH, diluted, and extracted with CHCl₃, yielding 0.17 g. neutral material. The alk. layer, acidified and extracted with warm CHCl₃ yielded 3.20 g. mixture of acids, m. 195-217°. Recrystallization from Me₂CO gave one isomer of VI, stout prisms, m. 236-7°; conversion of this acid to the Et ester with alc. HCl gave the same isomer, m. 134-5°, as above. Me ester, prepared by addition of CH₂N₂ in Et₂O to the acid in CHCl₃, colorless needles from CCl₄, m. 137-8°. From the KOH washings of the crude hydrogenation mixture was obtained 1.0 g. oily acidic material which was converted into the Me ester with MeOH and H₂SO₄; from this was isolated some unreduced Me ester of III, m. 224-6°, and a small amount of the Me ester, m. 137-38°, of IV. None of the compound with only the ring containing the carbomethoxy group reduced was isolated. The crude acid (m. 195-217°) above was oxidized in 80 ml. AcOH with 2.00 g. Cr₂O₄ in 2 ml. H₂O and 10 ml. AcOH at 15-18°; a portion of the solid keto acid from the CHCl₃ extracts recrystallized from Me₂CO as stout prisms, m. 228-30°. The remaining crude acid treated in CHCl₃ with excess CH₂N₂ in Et₂O yielded the Me ester of 4-(4-carboxyphenyl)cyclohexanone (VII), colorless platelets from Et₂O, m. 93-4.5°; 2,4-dinitrophenylhydrazone of the Me ester (92% from AcOMe), orange prisms, m. 223-4°.

Journal of the American Chemical Society published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C12H14IN, Safety of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Schultz, T. Wayne published the artcileEffect of substituent size and dimensionality on potency of phenolic xenoestrogens evaluated with a recombinant yeast assay, Application In Synthesis of 50670-76-3, the publication is Environmental Toxicology and Chemistry (2000), 19(11), 2637-2642, database is CAplus.

Estrogenicity was assessed using the Saccharomyces cerevisiae-based Lac-Z reporter assay and was reported as the logarithm of the inverse of the 50% molar β-galactosidase activity (log[EC₅₀^-1]). Previous studies indicated that the position, size, and shape of the nonphenolic moiety of xenoestrogens affects potency. In an effort to quantify the relationship between the size and shape of the nonphenolic moiety and estrogenic potency, a series of primarily hydrocarbon, para-substituted phenols were evaluated. There is a general trend of increase in estrogenicity with increased substituent size. Attempts were made to correlate estrogenic activity with a variety of mol. parameters. These parameters included two-dimensional mol. connectivity and other topol. indexes, MO properties and other assorted steric properties, as well as hydrophobicity. Regression anal. revealed that hydrophobicity, because of its colinearity with size, was moderately correlated with estrogenic activity (r_adj² = 0.431). Among the parameters describing the bulk and/or shape of the mol., the second-order path mol. connectivity for the substituent (²χ_p(sub)) was the single best parameter correlated with estrogenicity. It modeled activity by the relationship log(EC₅₀^-1) = 0.925(²χ_p(sub)) + 3.47;, s = 0.37, r_adj² = 0.868, f = 179,. In this model, the active chem. domain is defined by the presence of the para-phenolic ring, while the potency is quantified by the values of the substituent connectivity index. A comparison of 3-, 5-, and 7-d estrogenicity and potency ratio, as compared with 17-β-estradiol, showed some compounds that were not active after the third day but that were active on the fifth and seventh days of exposure. Potency varied with length of exposure, but the potency ratio did not change. These results suggest that activity with this assay should be reported after 5 d of exposure.

Environmental Toxicology and Chemistry published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C7H10BNO3, Application In Synthesis of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bialecka-Florjanczyk, Ewa published the artcileThe influence of structural changes of symmetrical dimers containing two phenyl groups on liquid crystalline behaviour, Product Details of C15H14O3, the publication is Liquid Crystals (2012), 39(10), 1216-1221, database is CAplus.

Some sym. dimeric compounds containing biphenyl, biphenylcarboxylic acid or benzoiloxyphenyl moieties and polymethylene spacers were synthesized. The mesogenic properties of the synthesized compounds were studied by optical microscopy, calorimetric and x-ray methods. The location and direction of the ester bonds has a crucial significance in mesophase formation.

Liquid Crystals published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Product Details of C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics