Category: 5003-48-5

Synthesis of benorylate, a derivative of acetylsalicylic acid was written by Zhang, Mingyu;Zhang, Peixing. And the article was included in Zhongguo Yaoxue Zazhi (Beijing, China) in 1989.Synthetic Route of C17H15NO5 The following contents are mentioned in the article:

2-AcOC₆H₄CO₂C₆H₄NHAc-4 (benorylate) was prepared from 2-acetylsalicyloyl chloride and 4-acetamidophenol in 55-65% yield. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Synthetic Route of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Synthetic Route of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

¹⁵N-NMR in the analysis of drugs. Part 4. Characterization of some analgesics-antipyretics was written by Cizmarik, J.;Lycka, A.. And the article was included in Pharmazie in 1988.Formula: C17H15NO5 The following contents are mentioned in the article:

Analgesics and antipyretics can be determined by an ¹⁵N-NMR spectroscopic method. The ¹⁵N chem. shifts of 22 drugs are listed. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A different structural example of nonsteroidal antiinflammatory agents: Benorylate was written by Iskit, Ayfer;Olgen, Sureyya;Nebioglu, Dogu. And the article was included in Ankara Universitesi Eczacilik Fakultesi Dergisi in 1998.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

A review with 56 references on the design, synthesis, pharmacol. and physicochem. properties and structure-activity relationships of Benorylate. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hepatotoxic metabolic activation of paracetamol and its derivatives, phenacetin and benorilate: oxygenation or electron transfer? was written by De Vries, J.. And the article was included in Biochemical Pharmacology in 1981.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

A review with 68 references on the hepatotoxicity of paracetamol [103-90-2], phenacetin [62-44-2], and benorilate [5003-48-5]. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation of benorylate suspension was written by Wu, Wang-Tong. And the article was included in Zhongguo Yiyao Gongye Zazhi in 1998.Related Products of 5003-48-5 The following contents are mentioned in the article:

In order to select suspending agents, the suspensions were examined by determination of their ratio of settling volume and redispersibility. The benorylate suspension prepared with tragacanth as a suspending agent was more stable than others. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Related Products of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of TO-125 (benorilate) on the central nervous system was written by Fujita, Mitsunobu;Ishii, Makoto;Shibuya, Takeshi. And the article was included in Tokyo Ika Daigaku Zasshi in 1978.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

TO-125 (I) [5003-48-5], an analgesic drug, administered orally to rabbits at 500 mg/kg slightly inhibited spontaneous elec. activity in the brain but had no significant effect on the central nervous system. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The study on the synthesis of benorilate was written by Teng, Xiao-bo;Qian, Jie. And the article was included in Shandong Huagong in 2009.Application of 5003-48-5 The following contents are mentioned in the article:

A review with 13 references Benorilate is a good non-steroidal antipyretic analgesics, product of structurally modified ester of aspirin and N-acetyl-p-aminophenol. The methods of synthesis of benorilate were reviewed. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Combination of TLC, GLC (OV 1 and OV 17) and HPLC (RP 18) for a rapid detection of drugs, intoxicants and related compounds was written by Daldrup, T.;Susanto, F.;Michalke, P.. And the article was included in Fresenius’ Zeitschrift fuer Analytische Chemie in 1981.Formula: C17H15NO5 The following contents are mentioned in the article:

Relative retention times for 570 drugs and related compounds on 8 chromatog. systems were reported. TLC employing silica gel plates, gas chromatog. employing 3% OV-1 on Chromosorb W-HP, and reversed-phase high-pressure chromatog. employing octadecylsilanized columns were described. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Determination of benorylate and its impurities by RP-HPLC was written by Chao, Ruobing;Chen, Tao;Ding, Shizhi. And the article was included in Yaoxue Xuebao in 1999.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

The contents of benorylate, and of its related substances paracetamol, acetyl paracetamol, aspirin, salicylic acid and salophen, and its impurities were determined by RP-HPLC at 240 nm on an ODS column with MeOH-H₂O (56:44, pH 3.5) as the mobile phase. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Contribution to the microscopic characterization and identification of drugs. Part 12 was written by Kuhnert-Brandstaetter, Maria;Boesch, L.;Eckstein, G.. And the article was included in Scientia Pharmaceutica in 1978.SDS of cas: 5003-48-5 The following contents are mentioned in the article:

Morpholog., crystallog., and other physicochem. properties of 50 common drugs were determined under thermomicroscope. Data in relation to m.p., eutectic temperatures with various compounds, glass powder indexes, red and Na light temperatures were tabulated. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5SDS of cas: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics