Category: 4522-93-4

Korhonen, Ilpo O. O.; Lind, Maija A. published an article in Journal of Chromatography. The title of the article was 《Gas-liquid chromatographic analyses. XLII. Retention behavior of C1-C12 n-alkyl esters of benzoic and pentafluorobenzoic acids on SE-30 and OV-351 capillary columns》.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate The author mentioned the following in the article:

The gas chromatog. separation of a mixture of C1-12 n-alkyl esters of benzoic and pentafluorobenzoic acids on low-polarity (SE-30) and highly polar (OV-351) capillary columns is described. The Kovats’ retention indexes for the fluorinated isomers are given. The results are compared with those reported by K. and L. (1985) for the corresponding n-alkyl benzoates by showing the retention index increments owing to the perfluoro substitution in the acyl chain at a variety of temperatures The results came from multiple reactions, including the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Petrachenko, N. E.; Vovna, V. I.; Furin, G. G. published an article in Zhurnal Organicheskoi Khimii. The title of the article was 《He(I) photoelectron spectra of fluorinated benzoic acid derivatives》.Name: Ethyl 2,3,4,5,6-pentafluorobenzoate The author mentioned the following in the article:

Photoelectron spectra of RC6H4CONH2 (R = 3-F, 2-F), 2,6-F2C6H3CONH2, 4-RC6X4CONHOH (R = F, X = H; R = H, X = F), C6F5CONHX (X = H, OH), and C6F5COR1 (R1 = OEt, C6F5) were obtained and interpreted with the aid of MNDO calculations Increasing the extent of fluorination leads to approx. equal stabilization of π MO and orbitals localized on the heteroatoms of the substituents.Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Name: Ethyl 2,3,4,5,6-pentafluorobenzoate) was used in this study.

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Name: Ethyl 2,3,4,5,6-pentafluorobenzoate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Electrochemical reduction of fluorinated aromatic carboxylic acids》 was published in Journal of the Chemical Society in 1972. These research results belong to Drakesmith, F. G.. Application of 4522-93-4 The article mentions the following:

Pentafluorobenzoic acid was electrochem. reduced in HClO4 to give 60% pentafluorobenzyl alc., and in aqueous Et4NBF4 to give, e.g., 40% 2,3,5,6-tetrafluorobenzoic acid (I) and 55% 2,3,5,6-tetrafluorobenzyl alc. Similar reduction of 4-chloro-, 4-amino-, and 4-methoxytetrafluorobenzoic acids, I, pentafluorobenzaldehyde, Et pentafluorobenzoate, and pentafluorobenzamide gave products dependent on the potential of the cathode, the acidity, and the type of ions in the base electrolyte. In the experiment, the researchers used many compounds, for example, Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application of 4522-93-4)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters.Application of 4522-93-4 They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Reactions of sodium pentafluorophenolate with substituted pentafluorobenzenes》 was published in Journal of Organic Chemistry in 1967. These research results belong to De Pasquale, Ralph J.; Tamborski, Christ. Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate The article mentions the following:

NaOC6F5 was prepared by proton exchange using NaOMeMeOH. This salt was freed from residual MeOH and treated with a series of substituted pentafluorobenzenes (C6F5R, R = CF3, CO2Et, C6F5, Br, Cl, F, H) using HCONMe2 as solvent. The major product arising from displacement of F para to the substituent was a fluorinated diphenyl ether. For some substituents (Cl, Br, H), displacement of o-F was competitive but minor. Mixtures of triphenyl ethers were occasionally observed. The relative reaction rates of these pentafluorobenzenes with NaOC6F5 were measured in HCONMe2 at 106°. These values when plotted against Hammett’s substituent constant σρ gave a reasonably straight line. From the slope, the σρ of a pentafluorophenyl group can be estimated as 0.4. The halide ion mobilities were qual. measured as F > Cl or Br which is consistent with a 2-step addition-elimination mechanism where the first step is ratedetg. 15 references. In the experimental materials used by the author, we found Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Ethyl 2,3,4,5,6-pentafluorobenzoateOn October 3, 2012 ,《π-π Interaction Assisted Hydrodefluorination of Perfluoroarenes by Gold Hydride: A Case of Synergistic Effect on C-F Bond Activation》 was published in Journal of the American Chemical Society. The article was written by Lv, Hongbin; Zhan, Jin-Hui; Cai, Yuan-Bo; Yu, Yi; Wang, Bingwu; Zhang, Jun-Long. The article contains the following contents:

“”Synergistic effect”” is prevalent in natural metalloenzymes in activating small mols., and the success has inspired the development of artificial catalysts capable of unprecedented organic transformations. In this work, we found that the attractive π-π interaction between organic additives (as electron-donors) and the perfluorinated arenes (as electron acceptors) is effective in gold hydride catalyzed activation of C-F bonds, specifically hydrodefluorination (HDF) of perfluoroarenes catalyzed by the Sadighi’s gold hydrides [(NHC)AuH] (NHC = N-heterocyclic carbene). Although a weak interaction between [(NHC)AuH] and perfluoroarenes was observed from 1H NMR and UV-vis spectroscopies, low reactivity of [(NHC)AuH] toward HDF was found. In contrast, in the presence of p-N,N-dimethylaminopyridine (DMAP), the HDF of perfluoroarenes with silanes can be efficiently catalyzed by [(NHC)AuH], resulting in mainly the para-hydrodefluorinated products with up to 90% yield and 9 turnovers. The yield of the reaction increases with the more electron-withdrawing groups and degree of fluorination on the arenes, and the HDF reaction also tolerates different function groups (such as formyl, alkynyl, ketone, ester, and carboxylate groups), without reduction or hydrogenation of these function groups. To reveal the role of DMAP in the reactions, the possible π-π interaction between DMAP and perfluoroarenes was suggested by UV-vis spectral titrations, 1H NMR spectroscopic studies, and DFT calculations Moreover, 1H and 19F-NMR studies show that this π-π interaction promotes hydrogen transfer from [(NHC)AuH] to pyridyl N atom, resulting in C-F bond cleavage. The interpretation of π-π interaction assisted C-F activation is supported by the reduced activation barriers in the presence of DMAP (31.6 kcal/mol) than that in the absence of DMAP (40.8 kcal/mol) for this reaction. An anal. of the charge distribution and transition state geometries indicate that this HDF process is controlled by the π-π interaction between DMAP and perfluoroarenes, accompanied with the changes of partial at. charges. In the experimental materials used by the author, we found Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Recommanded Product: Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Recommanded Product: Ethyl 2,3,4,5,6-pentafluorobenzoate They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2013,Angewandte Chemie, International Edition included an article by Lv, Hongbin; Cai, Yuan-Bo; Zhang, Jun-Long. Category: esters-buliding-blocks. The article was titled 《Copper-Catalyzed Hydrodefluorination of Fluoroarenes by Copper Hydride Intermediates》. The information in the text is summarized as follows:

We have reported the first example of copper-catalyzed hydrodefluorination of fluoroarenes using silanes as a hydrogen source. Copper exhibited high reactivity and regioselectivity toward a broad scope of fluoroarenes. Moreover, copper hydrides were observed during catalytic process and the unprecedented reactivity toward C-F bonds has been demonstrated. Furthermore, DFT calculations suggest a mechanism for nucleophilic attack on the C-F bonds by the copper hydride. This work presents valuable insights for further studies using copper catalysts for C-F bond functionalization. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Category: esters-buliding-blocks)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Larionov, S. V.; Myachina, L. I.; Sheludyakova, L. A.; Korolkov, I. V.; Rakhmanova, M. I.; Plyusnin, P. E.; Vinogradov, A. S.; Karpov, V. M.; Platonov, V. E.; Fadeeva, V. P. published an article in Russian Journal of General Chemistry. The title of the article was 《Synthesis of Octafluorobiphenyl-4,4′-dicarboxylic acid and photoluminescent compounds based thereon》.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate The author mentioned the following in the article:

Octafluorobiphenyl-4,4′-dicarboxylic acid (H2L) and its complexes with Tb(III) and Eu(III) [Ln2(H2O)4(L)3·3H2O and Ln2(phen)2(L)3·2H2O] have been prepared; their structure has been elucidated from IR spectroscopy and X-ray diffraction anal. data. Thermal properties of the compounds have been studied. The complexes of Tb(III) and Eu(III) exhibit green and red photoluminescence, resp. The results came from multiple reactions, including the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lu, Jingzhi; Khetrapal, Navneet S.; Johnson, Jacob A.; Zeng, Xiao Cheng; Zhang, Jian published their research in Journal of the American Chemical Society on December 14 ,2016. The article was titled 《”π-Hole-π” interaction promoted photocatalytic hydrodefluorination via inner-sphere electron transfer》.Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate The article contains the following contents:

We describe a metal-free, photocatalytic hydrodefluorination (HDF) of polyfluoroarenes (FA) using pyrene-based photocatalysts (Py). The weak “”π-hole-π”” interaction between Py and FA promotes the electron transfer against unfavorable energetics (ΔGET up to 0.63 eV) and initiates the subsequent HDF. The steric hindrance of Py and FA largely dictates the HDF reaction rate, pointing to an inner-sphere electron transfer pathway. This work highlights the importance of the size and shape of the photocatalyst and the substrate in controlling the electron transfer mechanism and rates as well as the overall photocatalytic processes. The results came from multiple reactions, including the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solodukhin, Nikolai N.; Borisova, Nataliya E.; Churakov, Andrei V.; Zaitsev, Kirill V. published an article in Journal of Fluorine Chemistry. The title of the article was 《Substituted 4-(1H-1,2,3-triazol-1-yl)-tetrafluorobenzoates: Selective synthesis and structure》.Application of 4522-93-4 The author mentioned the following in the article:

Regioselective, simple and fast synthesis of a series of [2 + 3]-cycloaddition products I (R = Ph, CMe2OH, CH2OH, etc.) in reaction between Et 4-azido-2,3,5,6-tetrafluorobenzoate and a number of substituted alkynes was elaborated under conditions of copper-catalyzed click chem. reaction. The optimized conditions include application of CuBr and Et3N in dichloromethane. The mol. structure of compound I (R = Ph) in solid state was established by X-ray anal. After reading the article, we found that the author used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application of 4522-93-4)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Application of 4522-93-4 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Vinogradov, A. S.; Krasnov, V. I.; Platonov, V. E. published an article on January 31 ,2008. The article was titled 《Organozinc reagents from polyfluoroarenes: preparation and reactions with allyl halides. Synthesis of allylpolyfluoroarenes》, and you may find the article in Russian Journal of Organic Chemistry.Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate The information in the text is summarized as follows:

Organozinc compounds of the general formula ArFZnX (X = Cl, ArF) were synthesized by reactions of Zn with chloropolyfluoroarenes and of Zn/SnCl2 with polyfluoroarenes. Polyfluorinated organozinc compounds reacted with allyl chloride and allyl bromide to give the corresponding allyl-substituted polyfluoroarenes. The reactions with allyl chloride were carried out in the presence of copper(I) salts (CuCl or CuI). In the experiment, the researchers used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics