Category: 4522-93-4

Miller, A. O.; Furin, G. G. published an article on February 28 ,1989. The article was titled 《Reaction of polyfluoro aromatic compounds with sodium nitrite》, and you may find the article in Zhurnal Organicheskoi Khimii.Category: esters-buliding-blocks The information in the text is summarized as follows:

Reaction of C6F5R (R = O2N, cyano, EtO2C) with NaNO2 in DMSO afforded p-RC6F4OH in 80, 90, and 80% yields, resp.; i.e., exclusively products of O substitution. C6HF5 afforded 2,3,5,6-tetrafluorophenol and 2,4,5-trifluoro-6-nitrophenol in a 3:1 ratio. O-substitution products are formed with electron-accepting R. In addition to this study using Ethyl 2,3,4,5,6-pentafluorobenzoate, there are many other studies that have used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Category: esters-buliding-blocks) was used in this study.

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Aromatic nucleophilic substitution. XIII. Reaction of pentafluoro benzenes with sodium ethylate and with methyl- and dimethylamines》 were Kobrina, L. S.; Furin, G. G.; Yakobson, G. G.. And the article was published in Zhurnal Organicheskoi Khimii in 1970. Electric Literature of C9H5F5O2 The author mentioned the following in the article:

The substitution reactions of C6F5X with EtONa, MeNH2 or Me2NH give either ο-YC6F5X (I) or p-YC6F5X (II) (Y is OEt, MeNH, or Me2N, X is NO2, SO2Me, CO2Et, CO2H, or Ac) depending on solvent polarity. However, C6F5CF3 or C6F5CN gave only II in polar or nonpolar solvents. A cyclic intermediate is proposed in the case of I formation; it involves the interaction between O of X and the nucleophilic attacking agent. E.g. the reaction of MeNH2 with C6F5X gave the following product distributions (X, I-II ratio in C6H6 and in MeNO2 given): NO2, 77:23, 15:85; SO2Me, 58:42, 5:95; CO2H, 45:55, 0-98; CO2Et, 35:65, 5:95; Ac, 36:64, 0:98; CN, 6:94, 0:98; CF3, 0:98, 0:98. After reading the article, we found that the author used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Electric Literature of C9H5F5O2)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Electric Literature of C9H5F5O2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《Catalytic C-F Bond Activation of Perfluoroarenes by Tricoordinated Gold(I) Complexes》 was published in Advanced Synthesis & Catalysis in 2012. These research results belong to Zhan, Jin-Hui; Lv, Hongbin; Yu, Yi; Zhang, Jun-Long. Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate The article mentions the following:

The authors report the first example of gold catalyzing C-F bond activation for perfluoroarenes in the presence of silanes. Tricoordinated gold(I) complexes supported by Xantphos-type ligands, such as Xantphos and tBuXantphos ligands, exhibit efficacy in the hydrodefluorination (HDF) of various types of perfluoroarenes. For [tBuXantphosAu(AuCl2)], the highest turnover number is up to 1000 in the HDF of pentafluoronitrobenzene with diphenylsilane. An examination of functional group tolerance shows the orthogonality of this gold(I) catalytic protocol to ketone, ester, carboxylate, alkynyl, alkenyl and amide groups, suggesting its potential application in chemoselective C-F activations. Mechanistic studies show that the equilibrium between tetracoordinated [L2Au]+ and [LAu]+ is important for the reactivity of gold catalysts, which is dependent on the sterically bulky group of Xantphos-type ligands. Also, computational studies for the possible reaction pathways suggest that direct oxidative addition of C-F bonds by gold(I) cation might be the key step during these catalytic reactions. In the experiment, the researchers used many compounds, for example, Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

《challenges of fast sampling of volatiles for thermal desorption gas chromatog. – mass spectrometry》 was written by Marcillo, Andrea; Weiss, Brigitte M.; Widdig, Anja; Birkemeyer, Claudia. Category: esters-buliding-blocks And the article was included in Journal of Chromatography A on April 26 ,2020. The article conveys some information:

Fast active sampling of volatile organic compounds (VOCs) under field conditions still is a great challenge especially when the exposure time to the source of emissions is a restricting factor. Hence, to identify ideal conditions for such applications, we systematically compared fast active sampling of VOCs collected on two common adsorbents under two regimes: first, very low gas volumes (from 300 mL) sampled at nominal flow rate and, second, sampling at the maximal applicable flow rate (0.5 L/min) before loss of sorbent material was experienced. For XAD-2 and Tenax TA, efficient sorbents for on-site VOC-sampling followed by thermal desorption GC-MS, significant differences in the signal response of volatile compounds were related not only to the varied exptl. factors alone, but also to their interactions and to compound volatility. In the first regime, volatiles (∼0.004-3.13 mM) from Tenax TA gave the highest signal response only above 800 mL sampled gas volume while at low concentrations (∼0.004-0.12 mM), satisfactory recovery from XAD-2 required longer analyte-sorbent interaction. For the second regime, the relative recovery was severely impaired down to 73 ± 23%, n = 56 for Tenax TA and 72 ± 17%, n = 56 for XAD-2 at intermediate concentration, and 79 ± 11%, n = 84 for Tenax TA at high concentration compared to the relative recovery at standard flow rate. Neither Tenax TA nor XAD-2 provided a 100% total recovery (calculated using breakthrough values) for any of the evaluated compounds Finally, two-way and three-way interactions identified in a multi-variable model, explained not only the dependence of the signal response on different exptl. variables, but also their complex interplay affecting the recovery of the VOCs. In conclusion, we show for the first time that XAD-2, a material only recently introduced for the adsorption of volatiles from the gas phase, competes well with the standard material Tenax TA under conditions of fast sampling. Due to the similar absolute recovery with Tenax TA even at low concentration and with regard to the better detection limits, we consider XAD-2 the better choice for fast sampling of VOCs, particularly with low sample volumes at regular flow. For fast sampling with high flow rate, however, both sorbents might be selected only if the corresponding recovery loss can be accepted for the study. In the experiment, the researchers used many compounds, for example, Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Category: esters-buliding-blocks)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Category: esters-buliding-blocks Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthetic Route of C9H5F5O2On September 8, 2017 ,《XAD-2-A useful alternative to Tenax TA for analysis of biogenic volatiles employing thermal desorption coupled with gas chromatography-mass spectrometry》 was published in Journal of Chromatography A. The article was written by Marcillo, Andrea; Jakimovska, Viktorija; Widdig, Anja; Birkemeyer, Claudia. The article contains the following contents:

Volatile organic compounds (VOCs) are commonly collected from gaseous samples by adsorption to materials such as the porous polymer Tenax TA. Adsorbed compounds are subsequently released from these materials by thermal desorption (TD) and separated then by gas chromatog. (GC) with flame ionization (FID) or mass spectrometry (MS) detection. Tenax TA is known to be particularly suitable for nonpolar to semipolar volatiles, however, many volatiles from environmental and biol. samples possess a rather polar character. Therefore, the authors tested if the polymer XAD-2, which so far is widely used to adsorb organic compounds from aqueous and organic solvents, could provide a broader coverage for (semi)polar VOCs during gas-phase sampling. Mixtures of volatile compounds covering a wide range of volatility (b.p. 20-256°) and different chem. classes were introduced by liquid spiking into sorbent tubes with one of the two porous polymers, Tenax TA or XAD-2, and analyzed by TD/GC-MS. At 1st, an internal standard mixture composed of 17 authentic standards was used to optimize desorption temperature with respect to sorbent degradation and loading time for calibration. Secondly, the authors tested the detectability of a complex standard mixture composed of 57 volatiles, most of them common constituents of the body odor of mammals. Also, the performance of XAD-2 compared with Tenax TA was assessed as limit of quantitation and linearity for the internal standard mixture and 33 compounds from the complex standard mixture Volatiles were analyzed in a range between 0.01-∼250 ng/tube depending on the compound and material. Lower limits of quantitation were 0.01-3 ng ± <25% relative standard deviation (R2 > 0.9). The authors found different kinetics for compound adsorption with XAD-2, and a partially better sensitivity in comparison with Tenax TA. For these analytes, XAD-2 might be recommended as an alternative of Tenax TA for TD/GC-MS anal. The experimental process involved the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Synthetic Route of C9H5F5O2)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Synthetic Route of C9H5F5O2 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Adonin, N. Yu.; Starichenko, V. F. published an article on January 31 ,2000. The article was titled 《Regioselective ortho-hydrodefluorination of pentafluorobenzoic acid by low-valent nickel complexes》, and you may find the article in Journal of Fluorine Chemistry.Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate The information in the text is summarized as follows:

2,3,4,5-Tetrafluorobenzoic and 3,4,5-trifluorobenzoic acids were prepared in high yields by reaction of C6F5COOH with zinc in the presence of NiCl2-2′-bipyridine (or 1,10-phenanthroline) complexes. In the experimental materials used by the author, we found Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. Quality Control of Ethyl 2,3,4,5,6-pentafluorobenzoate They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Fluorine-19 NMR spectra of substituted pentafluorobenzenes》 were Pushkina, L. N.; Stepanov, A. P.; Zhukov, V. S.; Naumov, A. D.. And the article was published in Zhurnal Organicheskoi Khimii in 1972. Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate The author mentioned the following in the article:

The value and sign of the meta spin-spin interaction constants in the 19F NMR spectra of 65 C6F5R correlated with the chem. shifts of the resp. F atoms. The experimental part of the paper was very detailed, including the reaction process of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. Reference of Ethyl 2,3,4,5,6-pentafluorobenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The author of 《Polyfluorinated aromatic esters. Preparation and carbonyl stretching frequencies》 were Filler, Robert; White, James F.; Kacmarek, Andrew J.; Solomon, Irvine J.. And the article was published in Canadian Journal of Chemistry in 1966. SDS of cas: 4522-93-4 The author mentioned the following in the article:

RCO2R’ (R, R’ = Ph, C6F5, Et, CF3, or CF3CH2) are prepared and the ir spectra are discussed in terms of inductive and mesomeric effects. The 4 canonical structures I-IV are considered. The experimental process involved the reaction of Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4SDS of cas: 4522-93-4)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.SDS of cas: 4522-93-4 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Jingjing; Zhao, Xiao; Yang, Jin-Dong; Cheng, Jin-Pei published an article on January 7 ,2022. The article was titled 《Diazaphospholene-Catalyzed Hydrodefluorination of Polyfluoroarenes with Phenylsilane via Concerted Nucleophilic Aromatic Substitution》, and you may find the article in Journal of Organic Chemistry.Recommanded Product: 4522-93-4 The information in the text is summarized as follows:

The metal-free catalytic C-F bond activation of polyfluoroarenes was achieved with diazaphospholene as the catalyst and phenylsilane as the terminal reductant. D. functional theory calculations suggested a concerted nucleophilic aromatic substitution mechanism. In the experiment, the researchers used Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Recommanded Product: 4522-93-4)

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters. They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Recommanded Product: 4522-93-4 They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoateOn November 30, 1981 ,《Fluoro ketones. V. Reactions of alkyl and aryllithium compounds with perfluoroalkyl ether esters》 appeared in Journal of Fluorine Chemistry. The author of the article were Chen, Loomis S.; Tamborski, Christ. The article conveys some information:

BuLi and aryllithium compounds reacted with a perfluoroalkyl ether ester at -78° to produce perfluoroalkyl ether ketones. Steric hindrance adjacent to the carbonyl group has an important effect on rates of reactions. Low reaction temperature is an important factor when secondary esters are used. At >-30° the decreased yields of ketone was due to the instability of the intermediate Li salt of the hemiketal which decomposed to an aryl ester and a perfluorinated olefin.Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate) was used in this study.

Ethyl 2,3,4,5,6-pentafluorobenzoate(cas: 4522-93-4) belongs to esters.Application In Synthesis of Ethyl 2,3,4,5,6-pentafluorobenzoate They are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils.Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics