Category: 4492-02-8

Extended knowledge of C10H14N2O2

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4492-02-8, name is Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., name: Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 4492-02-8, name is Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., name: Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Preparation 5 Indazole-3-Carboxylic Acid A mixture of 4,5,6,7-tetrahydroindazole-3-carboxylic acid ethyl ester (21.0 g, 108 mmol), 5% palladium on carbon (7.0 g solid, 3.29 mmol of Pd), and 210 mL of cymene was heated to reflux for 38 hours. At this point complete conversion to the indazole-3-carboxylic acid ethyl ester was shown by TLC (silica gel, 3:1 ethyl acetate-heptane). The reaction was cooled to 120 C. and the 5% palladium on carbon was removed by filtration.

According to the analysis of related databases, 4492-02-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Eli Lilly and Company; US6069152; (2000); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Some tips on 4492-02-8

The synthetic route of Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate has been constantly updated, and we look forward to future research findings.

These common heterocyclic compound, 4492-02-8, name is Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Formula: C10H14N2O2

Example 1 IndazoLe-3-Carboxylic Acid A mixture of 4,5,6,7-tetrahydroindazole-3-carboxylic acid ethyl ester (21.0 g, 108 mmol), 5% palladium on carbon (7.0 g solid, 3.29 mmol of Pd), and 210 mL of cymene was heated to reflux for 38 hours. At this point complete conversion to the indazole-3-carboxylic acid ethyl ester was shown by TLC (silica gel, 3:1 ethyl acetate-heptane). The reaction was cooled to 120 C. and the 5% palladium on carbon was removed by filtration.

The synthetic route of Ethyl 4,5,6,7-tetrahydro-1H-indazole-3-carboxylate has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Eli Lilly and Company; US5914405; (1999); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics